MX351996B - Uso de un derivado de pirazol en el tratamiento de exacerbaciones agudas de la enfermedad pulmonar obstructiva cronica. - Google Patents
Uso de un derivado de pirazol en el tratamiento de exacerbaciones agudas de la enfermedad pulmonar obstructiva cronica.Info
- Publication number
- MX351996B MX351996B MX2014011291A MX2014011291A MX351996B MX 351996 B MX351996 B MX 351996B MX 2014011291 A MX2014011291 A MX 2014011291A MX 2014011291 A MX2014011291 A MX 2014011291A MX 351996 B MX351996 B MX 351996B
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- pulmonary disease
- chronic obstructive
- obstructive pulmonary
- acute exacerbations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
El uso de la 3-[5-amino-4-(3-ciano-benzoil)-pirazol-1-il]-N-ciclop ropil-4-metil-benzamida o de un derivado farmacéuticamente aceptable de la misma, en la elaboración de un medicamento para el tratamiento de las exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica. El tratamiento puede implicar una sola dosis del ingrediente activo mediante administración oral.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261613187P | 2012-03-20 | 2012-03-20 | |
PCT/EP2013/055730 WO2013139809A1 (en) | 2012-03-20 | 2013-03-19 | Use of a pyrazole derivative in the treatment of acute exacerbations of chronic obstructive pulmonary disease |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014011291A MX2014011291A (es) | 2014-10-13 |
MX351996B true MX351996B (es) | 2017-11-06 |
Family
ID=47901996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014011291A MX351996B (es) | 2012-03-20 | 2013-03-19 | Uso de un derivado de pirazol en el tratamiento de exacerbaciones agudas de la enfermedad pulmonar obstructiva cronica. |
Country Status (30)
Country | Link |
---|---|
US (2) | US9339491B2 (es) |
EP (1) | EP2827860B1 (es) |
JP (1) | JP6091593B2 (es) |
KR (1) | KR101793777B1 (es) |
CN (1) | CN104203234B (es) |
AU (1) | AU2013237503B2 (es) |
BR (1) | BR112014023107B1 (es) |
CA (1) | CA2866108C (es) |
CL (1) | CL2014002471A1 (es) |
CY (1) | CY1118327T1 (es) |
DK (1) | DK2827860T3 (es) |
ES (1) | ES2605942T3 (es) |
HK (1) | HK1200352A1 (es) |
HR (1) | HRP20161514T1 (es) |
HU (1) | HUE032004T2 (es) |
IL (1) | IL234537A (es) |
LT (1) | LT2827860T (es) |
MA (1) | MA37455B1 (es) |
MX (1) | MX351996B (es) |
NZ (1) | NZ628392A (es) |
PH (1) | PH12014502107B1 (es) |
PL (1) | PL2827860T3 (es) |
PT (1) | PT2827860T (es) |
RU (1) | RU2625762C2 (es) |
SG (1) | SG11201404941WA (es) |
SI (1) | SI2827860T1 (es) |
TN (1) | TN2014000350A1 (es) |
TW (1) | TWI583381B (es) |
WO (1) | WO2013139809A1 (es) |
ZA (1) | ZA201405871B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2600833C1 (ru) * | 2015-09-03 | 2016-10-27 | ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ" МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ (ФГБУ "РНЦРХТ" Минздрава России) | Способ лечения хронической обструктивной болезни легких |
RU2600822C1 (ru) * | 2015-09-03 | 2016-10-27 | ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ" МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ (ФГБУ "РНЦРХТ" Минздрава России) | Способ лечения хронического обструктивного бронхита |
JP6741774B2 (ja) | 2016-03-08 | 2020-08-19 | メレオ バイオファーマ 1 リミテッド | 慢性閉塞性肺疾患の急性増悪の治療のための投与レジメン |
AU2016397046B2 (en) * | 2016-03-08 | 2022-05-12 | Mereo Biopharma 1 Limited | Dosage regimen for the treatment of acute exacerbations of inflammatory conditions |
US10331542B2 (en) * | 2016-06-23 | 2019-06-25 | International Business Machines Corporation | System and method for detecting and alerting unexpected behavior of software applications |
GB201612240D0 (en) | 2016-07-14 | 2016-08-31 | Mereo Biopharma 1 Ltd | Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide |
GB201612238D0 (en) | 2016-07-14 | 2016-08-31 | Mereo Biopharma 1 Ltd | Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-Yl]-n-cyclopropyl-4-methylbenzamide |
US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
LT3691620T (lt) | 2017-10-05 | 2022-09-26 | Fulcrum Therapeutics, Inc. | P38 kinazės inhibitoriai, sumažinantys dux4 ir pasrovinių genų raišką, skirti fshd gydymui |
WO2019116022A1 (en) | 2017-12-11 | 2019-06-20 | Mereo Biopharma 1 Limited | Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the prevention or reduction of acute exacerbations of chronic obstructive pulmonary disease |
PT3585382T (pt) | 2017-12-11 | 2021-08-19 | Mereo Biopharma 1 Ltd | Utilização de 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-n-ciclopropil-4-metilbenzamida no tratamento de exacerbações agudas da doença pulmonar obstrutiva crónica |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4838121B2 (ja) * | 2003-06-26 | 2011-12-14 | ノバルティス アーゲー | 5員ヘテロ環を基礎とするp38キナーゼ阻害剤 |
GB0603684D0 (en) * | 2006-02-23 | 2006-04-05 | Novartis Ag | Organic compounds |
-
2013
- 2013-03-19 HU HUE13710851A patent/HUE032004T2/en unknown
- 2013-03-19 BR BR112014023107-9A patent/BR112014023107B1/pt active IP Right Grant
- 2013-03-19 PL PL13710851T patent/PL2827860T3/pl unknown
- 2013-03-19 JP JP2015500892A patent/JP6091593B2/ja active Active
- 2013-03-19 CN CN201380015703.5A patent/CN104203234B/zh active Active
- 2013-03-19 AU AU2013237503A patent/AU2013237503B2/en active Active
- 2013-03-19 EP EP13710851.0A patent/EP2827860B1/en active Active
- 2013-03-19 KR KR1020147025904A patent/KR101793777B1/ko active IP Right Grant
- 2013-03-19 CA CA2866108A patent/CA2866108C/en active Active
- 2013-03-19 RU RU2014141893A patent/RU2625762C2/ru active
- 2013-03-19 SG SG11201404941WA patent/SG11201404941WA/en unknown
- 2013-03-19 NZ NZ628392A patent/NZ628392A/en unknown
- 2013-03-19 ES ES13710851.0T patent/ES2605942T3/es active Active
- 2013-03-19 DK DK13710851.0T patent/DK2827860T3/en active
- 2013-03-19 LT LTEP13710851.0T patent/LT2827860T/lt unknown
- 2013-03-19 MX MX2014011291A patent/MX351996B/es active IP Right Grant
- 2013-03-19 TW TW102109739A patent/TWI583381B/zh active
- 2013-03-19 PT PT137108510T patent/PT2827860T/pt unknown
- 2013-03-19 MA MA37455A patent/MA37455B1/fr unknown
- 2013-03-19 US US14/386,174 patent/US9339491B2/en active Active
- 2013-03-19 WO PCT/EP2013/055730 patent/WO2013139809A1/en active Application Filing
- 2013-03-19 SI SI201330397A patent/SI2827860T1/sl unknown
-
2014
- 2014-08-11 TN TNP2014000350A patent/TN2014000350A1/fr unknown
- 2014-08-11 ZA ZA2014/05871A patent/ZA201405871B/en unknown
- 2014-09-08 IL IL234537A patent/IL234537A/en active IP Right Grant
- 2014-09-17 CL CL2014002471A patent/CL2014002471A1/es unknown
- 2014-09-22 PH PH12014502107A patent/PH12014502107B1/en unknown
-
2015
- 2015-01-29 HK HK15101000.9A patent/HK1200352A1/zh unknown
-
2016
- 2016-04-29 US US15/143,356 patent/US20160243081A1/en not_active Abandoned
- 2016-11-16 HR HRP20161514TT patent/HRP20161514T1/hr unknown
- 2016-11-18 CY CY20161101194T patent/CY1118327T1/el unknown
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Legal Events
Date | Code | Title | Description |
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FG | Grant or registration |