MX348010B - Reprogramacion de celulas somaticas. - Google Patents

Reprogramacion de celulas somaticas.

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Publication number
MX348010B
MX348010B MX2009010847A MX2009010847A MX348010B MX 348010 B MX348010 B MX 348010B MX 2009010847 A MX2009010847 A MX 2009010847A MX 2009010847 A MX2009010847 A MX 2009010847A MX 348010 B MX348010 B MX 348010B
Authority
MX
Mexico
Prior art keywords
somatic cells
reprogramming
differentiated
methods
cells
Prior art date
Application number
MX2009010847A
Other languages
English (en)
Other versions
MX2009010847A (es
Inventor
Jaenisch Rudolf
Wernig Marius
J Lengner Christopher
Meissner Alexander
Tobias Brambrink Oliver
Grant Welstead G
Foreman Ruth
Hanna Yaqub
Original Assignee
Whitehead Inst Biomedical Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whitehead Inst Biomedical Res filed Critical Whitehead Inst Biomedical Res
Publication of MX2009010847A publication Critical patent/MX2009010847A/es
Publication of MX348010B publication Critical patent/MX348010B/es

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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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Abstract

La presente invención se refiere a una preparación purificada de células de mamífero pluripotentes aisladas, caracterizadas porque las células: (a) expresan Oct4 y Nanog endógeno; (b) se diferencian en tejidos que tienen las características de endodermo, mesodermo y ectodermo cuando se inyectan a ratones SCID; (c) no expresan un ácido nucleico que codifique para un marcado seleccionable unido operablemente a un gen de pluripotencia endógeno; y (d) son células somáticas de mamífero reprogramadas que comprenden polinucléotidos introducidos de manera exógena que codifican para Oct4, SOx2 y Klf4, pero no para c-Myc.
MX2009010847A 2007-04-07 2008-04-07 Reprogramacion de celulas somaticas. MX348010B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US92212107P 2007-04-07 2007-04-07
US95934107P 2007-07-12 2007-07-12
US3606508P 2008-03-12 2008-03-12
PCT/US2008/004516 WO2008124133A1 (en) 2007-04-07 2008-04-07 Reprogramming of somatic cells

Publications (2)

Publication Number Publication Date
MX2009010847A MX2009010847A (es) 2010-04-27
MX348010B true MX348010B (es) 2017-05-23

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015009872A MX352541B (es) 2007-04-07 2008-04-07 Reprogramación de células somáticas.
MX2009010847A MX348010B (es) 2007-04-07 2008-04-07 Reprogramacion de celulas somaticas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2015009872A MX352541B (es) 2007-04-07 2008-04-07 Reprogramación de células somáticas.

Country Status (9)

Country Link
US (4) US9382515B2 (es)
EP (3) EP2626416A3 (es)
JP (8) JP2010523117A (es)
CN (2) CN101932705A (es)
AU (1) AU2008236629B2 (es)
CA (2) CA3071055A1 (es)
MX (2) MX352541B (es)
RU (1) RU2502799C2 (es)
WO (1) WO2008124133A1 (es)

Families Citing this family (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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