MX346524B - Diagnostico de infecciones virales mediante la deteccion de adn viral genómico e infeccioso mediante compatibilización molecular. - Google Patents

Diagnostico de infecciones virales mediante la deteccion de adn viral genómico e infeccioso mediante compatibilización molecular.

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Publication number
MX346524B
MX346524B MX2012012352A MX2012012352A MX346524B MX 346524 B MX346524 B MX 346524B MX 2012012352 A MX2012012352 A MX 2012012352A MX 2012012352 A MX2012012352 A MX 2012012352A MX 346524 B MX346524 B MX 346524B
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MX
Mexico
Prior art keywords
viral
dna
probes
detection
molecular combing
Prior art date
Application number
MX2012012352A
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English (en)
Other versions
MX2012012352A (es
Inventor
Conseiller Emmanuel
Mahiet Charlotte
Salvaire Fabrice
Barradeau Sébastien
Original Assignee
Genomic Vision
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Publication date
Application filed by Genomic Vision filed Critical Genomic Vision
Publication of MX2012012352A publication Critical patent/MX2012012352A/es
Publication of MX346524B publication Critical patent/MX346524B/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a un método para detectar in vitro la presencia de un genoma de virus de ADN o un ADN derivado viral en una célula, tejido o fluido biológico eucariótico infectado, utilizando peinado molecular u otros métodos de extensión de ácido nucleico junto con sondas, especialmente sondas de ácido nucleico, que tienen un diseño especial. Se describe un método para monitorear in vitro los efectos del tratamiento anti-viral, siguiendo la presencia de los polinucleótidos de ADN virales genómicos o derivados virales en una célula, tejido o fluido biológico infectado con virus. Detección de una forma infecciosa de un virus utilizando peinado molecular e hibridación de ADN. Un equipo que comprende sondas utilizadas para llevar a cabo estos métodos y una composición que comprende de las sondas.
MX2012012352A 2010-04-23 2011-04-19 Diagnostico de infecciones virales mediante la deteccion de adn viral genómico e infeccioso mediante compatibilización molecular. MX346524B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32739710P 2010-04-23 2010-04-23
PCT/IB2011/001048 WO2011132078A2 (en) 2010-04-23 2011-04-19 Diagnosis of viral infections by detection of genomic and infectious viral dna by molecular combing

Publications (2)

Publication Number Publication Date
MX2012012352A MX2012012352A (es) 2013-06-28
MX346524B true MX346524B (es) 2017-03-23

Family

ID=44511088

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012012352A MX346524B (es) 2010-04-23 2011-04-19 Diagnostico de infecciones virales mediante la deteccion de adn viral genómico e infeccioso mediante compatibilización molecular.

Country Status (10)

Country Link
US (4) US20110287423A1 (es)
EP (2) EP2561104B1 (es)
JP (2) JP2013524806A (es)
CN (2) CN103069010B (es)
BR (1) BR112012027151A8 (es)
CA (1) CA2796294C (es)
ES (1) ES2668802T3 (es)
IL (2) IL222545A (es)
MX (1) MX346524B (es)
WO (1) WO2011132078A2 (es)

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JP2014535050A (ja) * 2011-10-31 2014-12-25 ゲノミク ビジョン 生体試料におけるゲノム再編成を特定又は検出する方法
WO2013078302A1 (en) 2011-11-23 2013-05-30 Cornell University Methods for diagnosing human immunodeficiency virus infections
CN103074337B (zh) * 2012-12-04 2014-07-09 昆明寰基生物芯片产业有限公司 一段单纯疱疹病毒dna序列及应用
WO2015013681A1 (en) 2013-07-25 2015-01-29 Bio-Rad Laboratories, Inc. Genetic assays
CN112280792B (zh) * 2013-09-29 2022-06-24 上海泽润生物科技有限公司 人***瘤病毒基因，及载体，菌株，表达方法
CN104673796A (zh) * 2015-02-09 2015-06-03 暨南大学 靶向hsv-1病毒ul18基因的小干扰rna及应用
RU2018120004A (ru) * 2015-10-30 2019-12-02 Конинклейке Филипс Н.В. Способы, системы и процессы определения путей передачи инфекционных агентов
CN110168102A (zh) * 2016-11-15 2019-08-23 基因组影像公司 利用分子梳理监测经修饰的核酸酶诱导的基因编辑事件的方法
WO2018100431A1 (en) 2016-11-29 2018-06-07 Genomic Vision Method for designing a set of polynucleotide sequences for analysis of specific events in a genetic region of interest
WO2020109866A1 (en) 2018-11-30 2020-06-04 Genomic Vision Association between integration of viral as hpv or hiv genomes and the severity and/or clinical outcome of disorders as hpv associated cervical lesions or aids pathology
CN112877366A (zh) * 2020-03-10 2021-06-01 广州复能基因有限公司 用于检测来自dna或rna生物体的样品靶标的可掺入参照标准品
WO2021236116A1 (en) * 2020-05-20 2021-11-25 Delahoussaye Kevin Antiviral medicinal template
EP4251766A1 (en) 2020-11-25 2023-10-04 Genomic Vision Physical characterization of telomeres

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Also Published As

Publication number Publication date
WO2011132078A3 (en) 2012-01-26
US20110287423A1 (en) 2011-11-24
CN105734170A (zh) 2016-07-06
US20230127554A1 (en) 2023-04-27
EP2561104A2 (en) 2013-02-27
EP3000900B1 (en) 2018-02-28
WO2011132078A2 (en) 2011-10-27
BR112012027151A8 (pt) 2018-06-26
EP3000900A1 (en) 2016-03-30
CN103069010A (zh) 2013-04-24
JP2017184745A (ja) 2017-10-12
IL222545A0 (en) 2012-12-31
CN103069010B (zh) 2016-02-24
EP2561104B1 (en) 2015-11-04
BR112012027151A2 (pt) 2017-07-18
CA2796294C (en) 2019-03-26
MX2012012352A (es) 2013-06-28
ES2668802T3 (es) 2018-05-22
US20160047006A1 (en) 2016-02-18
US20190345570A1 (en) 2019-11-14
CA2796294A1 (en) 2011-10-27
IL250727A0 (en) 2017-04-30
IL222545A (en) 2017-03-30
JP2013524806A (ja) 2013-06-20

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