MX2022012812A - Métodos para tratar el síndrome de liberación de citocinas. - Google Patents

Métodos para tratar el síndrome de liberación de citocinas.

Info

Publication number
MX2022012812A
MX2022012812A MX2022012812A MX2022012812A MX2022012812A MX 2022012812 A MX2022012812 A MX 2022012812A MX 2022012812 A MX2022012812 A MX 2022012812A MX 2022012812 A MX2022012812 A MX 2022012812A MX 2022012812 A MX2022012812 A MX 2022012812A
Authority
MX
Mexico
Prior art keywords
cytokine release
methods
release syndrome
treating cytokine
treating
Prior art date
Application number
MX2022012812A
Other languages
English (en)
Inventor
Jacqueline M Mason
Mark R Bray
Xin Wei
Gordon Duncan
Original Assignee
Univ Health Network
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Health Network filed Critical Univ Health Network
Publication of MX2022012812A publication Critical patent/MX2022012812A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Se describe aquí un método para tratar a un sujeto con liberación aberrante de citocinas por una enfermedad o condición o con riesgo de desarrollar una liberación aberrante de citocinas por una enfermedad o condición; el método comprende administrar al sujeto una cantidad eficaz de un compuesto representado por la fórmula estructural (I): (ver fórmula) o una sal farmacéuticamente aceptable del mismo; las variables en la fórmula estructural (I) son como se describen en este documento.
MX2022012812A 2020-04-13 2021-04-12 Métodos para tratar el síndrome de liberación de citocinas. MX2022012812A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063009059P 2020-04-13 2020-04-13
US202063022956P 2020-05-11 2020-05-11
PCT/CA2021/050483 WO2021207828A1 (en) 2020-04-13 2021-04-12 Methods for treating cytokine release syndrome

Publications (1)

Publication Number Publication Date
MX2022012812A true MX2022012812A (es) 2023-01-30

Family

ID=78083464

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022012812A MX2022012812A (es) 2020-04-13 2021-04-12 Métodos para tratar el síndrome de liberación de citocinas.

Country Status (12)

Country Link
US (1) US20230144869A1 (es)
EP (1) EP4135695A1 (es)
JP (1) JP2023522618A (es)
KR (1) KR20230018365A (es)
CN (1) CN115867275A (es)
AU (1) AU2021257439A1 (es)
BR (1) BR112022020814A2 (es)
CA (1) CA3175420A1 (es)
IL (1) IL297314A (es)
MX (1) MX2022012812A (es)
TW (1) TW202203917A (es)
WO (1) WO2021207828A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
WO2021262040A1 (ru) * 2020-06-26 2021-12-30 Общество С Ограниченной Ответственностью "Валента-Интеллект" Применение производного глутаримида для терапии заболеваний, ассоциированных с аберрантной активностью интерлейкина-6
WO2023143384A1 (zh) * 2022-01-27 2023-08-03 四川海思科制药有限公司 一种抑制或降解hpk1激酶的化合物及其在医药中的用途
US20230340052A1 (en) * 2022-02-22 2023-10-26 Deka Biosciences, Inc. Method of reducing bispecific t cell engager or chimeric antigen receptor t cell mediated cytokine release syndrome using interleukins-4, -10, or a fusion protein thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008534502A (ja) * 2005-03-24 2008-08-28 アバニール・ファーマシューティカルズ マクロファージ遊走阻止因子の阻害剤としてのチエノピリジノン誘導体
CA2989684A1 (en) * 2015-06-25 2016-12-29 University Health Network Hpk1 inhibitors and methods of using same
CN109721620B (zh) * 2017-10-27 2022-05-13 药捷安康(南京)科技股份有限公司 Hpk1抑制剂及其用途
KR20210108433A (ko) * 2018-12-26 2021-09-02 얀센 파마슈티카 엔.브이. 티에노피리디논 화합물

Also Published As

Publication number Publication date
JP2023522618A (ja) 2023-05-31
IL297314A (en) 2022-12-01
KR20230018365A (ko) 2023-02-07
CN115867275A (zh) 2023-03-28
CA3175420A1 (en) 2021-10-21
AU2021257439A1 (en) 2022-12-15
BR112022020814A2 (pt) 2022-11-29
EP4135695A1 (en) 2023-02-22
WO2021207828A1 (en) 2021-10-21
US20230144869A1 (en) 2023-05-11
TW202203917A (zh) 2022-02-01

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