MX2022008950A - Moduladores del receptor s1p para el tratamiento de esclerosis multiple. - Google Patents
Moduladores del receptor s1p para el tratamiento de esclerosis multiple.Info
- Publication number
- MX2022008950A MX2022008950A MX2022008950A MX2022008950A MX2022008950A MX 2022008950 A MX2022008950 A MX 2022008950A MX 2022008950 A MX2022008950 A MX 2022008950A MX 2022008950 A MX2022008950 A MX 2022008950A MX 2022008950 A MX2022008950 A MX 2022008950A
- Authority
- MX
- Mexico
- Prior art keywords
- multiple sclerosis
- receptor modulators
- treating multiple
- amino
- neo
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente invención se refiere a usos de un modulador del receptor S1P, tal como el 2-amino-propano-1,3-diol 2-sustituto o derivados de 2-amino-propanol, por ejemplo un compuesto que comprende un grupo de la Fórmula (X): (ver Fórmula) para el tratamiento o la prevención de neo-angiogénesis asociada con una enfermedad desmielinizante, por ejemplo esclerosis múltiple.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0612721.1A GB0612721D0 (en) | 2006-06-27 | 2006-06-27 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022008950A true MX2022008950A (es) | 2022-08-11 |
Family
ID=36888144
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008016133A MX2008016133A (es) | 2006-06-27 | 2007-06-25 | Moduladores del receptor s1p para el tratamiento de esclerosis multiple. |
MX2022008950A MX2022008950A (es) | 2006-06-27 | 2008-12-16 | Moduladores del receptor s1p para el tratamiento de esclerosis multiple. |
MX2019012750A MX2019012750A (es) | 2006-06-27 | 2008-12-16 | Moduladores del receptor s1p para el tratamiento de esclerosis multiple. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008016133A MX2008016133A (es) | 2006-06-27 | 2007-06-25 | Moduladores del receptor s1p para el tratamiento de esclerosis multiple. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019012750A MX2019012750A (es) | 2006-06-27 | 2008-12-16 | Moduladores del receptor s1p para el tratamiento de esclerosis multiple. |
Country Status (21)
Country | Link |
---|---|
US (3) | US20100168078A1 (es) |
EP (4) | EP2698154A1 (es) |
JP (7) | JP2009541386A (es) |
KR (6) | KR20090024281A (es) |
CN (2) | CN101478961B (es) |
AU (7) | AU2007264031C1 (es) |
BR (1) | BRPI0713985A2 (es) |
CA (1) | CA2653569C (es) |
DE (1) | DE15177166T1 (es) |
DK (1) | DK2959894T3 (es) |
ES (1) | ES2887042T3 (es) |
GB (1) | GB0612721D0 (es) |
HK (1) | HK1214758A1 (es) |
HU (1) | HUE059922T4 (es) |
LT (1) | LT2959894T (es) |
MX (3) | MX2008016133A (es) |
PL (1) | PL2959894T3 (es) |
PT (1) | PT2959894T (es) |
RU (1) | RU2617502C2 (es) |
SI (1) | SI2959894T1 (es) |
WO (1) | WO2008000419A1 (es) |
Families Citing this family (29)
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GB0612721D0 (en) * | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
CN101674819A (zh) * | 2007-05-04 | 2010-03-17 | 诺瓦提斯公司 | S1p受体调节剂的用途 |
CN102076335A (zh) * | 2008-06-20 | 2011-05-25 | 诺瓦提斯公司 | 用于治疗多发性硬化的儿科组合物 |
BRPI0916968A2 (pt) | 2008-08-18 | 2015-11-24 | Novartis Ag | compostos para o tratamento de neuropatias periféricas, formulações farmacêuticas compreendendo os referidos compostos, e usos dos mesmos |
EP2177521A1 (en) | 2008-10-14 | 2010-04-21 | Almirall, S.A. | New 2-Amidothiadiazole Derivatives |
KR20110096584A (ko) * | 2008-12-18 | 2011-08-30 | 노파르티스 아게 | 1-[4-[1-(4-시클로헥실-3-트리플루오로메틸-벤질옥시이미노)-에틸]-2-에틸-벤질]-아제티딘-3-카르복실산의 헤미푸마레이트 염 |
CN102256942B (zh) * | 2008-12-18 | 2013-07-24 | 诺瓦提斯公司 | 1-(4-{1-[(e)-4-环己基-3-三氟甲基-苄氧基亚氨基]-乙基}-2-乙基-苄基)-氮杂环丁烷-3-甲酸的多晶型物 |
EP2379499B1 (en) * | 2008-12-18 | 2014-04-09 | Novartis AG | Hydrochloride salt of 1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl)-2-ethyl-benzyl)-azetidine-3-carboxylic acid |
EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
EP2210890A1 (en) | 2009-01-19 | 2010-07-28 | Almirall, S.A. | Oxadiazole derivatives as S1P1 receptor agonists |
EP2305660A1 (en) | 2009-09-25 | 2011-04-06 | Almirall, S.A. | New thiadiazole derivatives |
US20110124605A1 (en) * | 2009-11-20 | 2011-05-26 | Shreeram Aradhye | Use of an S1P Receptor Agonist |
IN2012DN05125A (es) * | 2009-11-24 | 2015-10-23 | Allergan Inc | |
EP2343287A1 (en) | 2009-12-10 | 2011-07-13 | Almirall, S.A. | New 2-aminothiadiazole derivatives |
EP2366702A1 (en) | 2010-03-18 | 2011-09-21 | Almirall, S.A. | New oxadiazole derivatives |
EP2390252A1 (en) | 2010-05-19 | 2011-11-30 | Almirall, S.A. | New pyrazole derivatives |
CN102120720B (zh) * | 2011-01-25 | 2013-05-22 | 上海华升生物科技有限公司 | 盐酸芬戈莫德的合成新方法 |
US20150218090A1 (en) * | 2011-10-21 | 2015-08-06 | Novartis Ag | Dosage regimen for an s1p receptor modulator or agonist |
WO2013140743A1 (ja) * | 2012-03-23 | 2013-09-26 | 日本電気株式会社 | 加入者サーバ、監視サーバ、移動端末、これらに関する方法、及びコンピュータ可読媒体 |
RU2506949C1 (ru) * | 2012-06-13 | 2014-02-20 | Открытое акционерное общество "Новосибхимфарм" | Фармацевтическая композиция агониста рецептора s1p для лечения демиелинизационных заболеваний |
CN102887829B (zh) * | 2012-09-05 | 2014-07-02 | 中国科学院上海药物研究所 | 芬戈莫德粘酸盐及其晶体的制备方法和用途 |
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GB612721A (en) | 1946-02-11 | 1948-11-17 | Richard William Bailey | Improvements in combustion product power plant |
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AR025068A1 (es) | 1999-08-10 | 2002-11-06 | Bayer Corp | Pirazinas sustituidas y piridazinas fusionadas, composicion farmaceutica que las comprenden, uso de dichos compuestos para la manufactura de un medicamentocon actividad inhibidora de angiogenesis |
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KR20040048231A (ko) | 2002-12-02 | 2004-06-07 | 주식회사 두산 | 신생혈관생성 억제제 및 그를 포함한 암 치료용 키트 |
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KR101367574B1 (ko) | 2003-04-08 | 2014-02-25 | 미쓰비시 타나베 파마 코퍼레이션 | S1p 수용체 아고니스트 및 당 알콜을 포함하는 고형 제약 조성물 |
MY150088A (en) | 2003-05-19 | 2013-11-29 | Irm Llc | Immunosuppressant compounds and compositions |
AR044402A1 (es) | 2003-05-19 | 2005-09-14 | Irm Llc | Compuestos heterociclicos y su uso como inmunodepresores. composiciones farmaceuticas que los contienen. |
CA2524027C (en) * | 2003-05-19 | 2013-03-19 | Irm Llc | Immunosuppressant compounds and compositions |
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JP2008521827A (ja) * | 2004-11-29 | 2008-06-26 | ノバルティス アクチエンゲゼルシャフト | S1p受容体アゴニストの投与レジメン |
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GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
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-
2006
- 2006-06-27 GB GBGB0612721.1A patent/GB0612721D0/en not_active Ceased
-
2007
- 2007-06-25 EP EP13186359.9A patent/EP2698154A1/en not_active Withdrawn
- 2007-06-25 KR KR1020097001390A patent/KR20090024281A/ko not_active Application Discontinuation
- 2007-06-25 KR KR1020157030213A patent/KR20150122812A/ko not_active Application Discontinuation
- 2007-06-25 EP EP07764828A patent/EP2037906A1/en not_active Withdrawn
- 2007-06-25 EP EP15177166.4A patent/EP2959894B1/en active Active
- 2007-06-25 PT PT151771664T patent/PT2959894T/pt unknown
- 2007-06-25 MX MX2008016133A patent/MX2008016133A/es not_active Application Discontinuation
- 2007-06-25 DK DK15177166.4T patent/DK2959894T3/da active
- 2007-06-25 PL PL15177166.4T patent/PL2959894T3/pl unknown
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