MX2022000826A - Composiciones de forma de dosificacion que comprenden un inhibidor de tirosina cinasa de bruton. - Google Patents
Composiciones de forma de dosificacion que comprenden un inhibidor de tirosina cinasa de bruton.Info
- Publication number
- MX2022000826A MX2022000826A MX2022000826A MX2022000826A MX2022000826A MX 2022000826 A MX2022000826 A MX 2022000826A MX 2022000826 A MX2022000826 A MX 2022000826A MX 2022000826 A MX2022000826 A MX 2022000826A MX 2022000826 A MX2022000826 A MX 2022000826A
- Authority
- MX
- Mexico
- Prior art keywords
- bruton
- crystalline
- inhibitor
- salts
- free base
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Abstract
La invención se refiere, en general, a composiciones farmacéuticas en comprimido que comprenden ácido fumárico y el compuesto de base libre de (S)-2-(3'-(hidroximetil)-1-metil-5-((5- (2-metil-4-(oxetan-3-il)piperazin-1-il)piridin-2-il)amino)-6-oxo- 1,6-dihidro-[3,4'-bipiridin]-2'-il)-7,7-dimetil-2,3,4,6,7,8-hexah idro-1H-ciclopenta[4,5]pirrolo[1,2-a]pirazin-1-ona que es un inhibidor de la tirosina cinasa de Bruton. La invención se refiere además a dispersiones sólidas amorfas que comprenden al menos un polímero y la base libre del compuesto inhibidor de la cinasa de Bruton. La invención se refiere además a sales cristalinas de mesilato, sales cristalinas de cloruro y sales cristalinas de sulfato de la base libre del compuesto inhibidor de la cinasa de Bruton. En algunas modalidades, las sales cristalinas son polimorfos individuales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662301373P | 2016-02-29 | 2016-02-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022000826A true MX2022000826A (es) | 2022-02-16 |
Family
ID=58162610
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018008754A MX2018008754A (es) | 2016-02-29 | 2017-02-27 | Composiciones de forma de dosificacion que comprenden un inhibidor de tirosina cinasa de bruton. |
| MX2022000826A MX2022000826A (es) | 2016-02-29 | 2018-07-16 | Composiciones de forma de dosificacion que comprenden un inhibidor de tirosina cinasa de bruton. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018008754A MX2018008754A (es) | 2016-02-29 | 2017-02-27 | Composiciones de forma de dosificacion que comprenden un inhibidor de tirosina cinasa de bruton. |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US10246461B2 (es) |
| EP (2) | EP3423059B1 (es) |
| JP (4) | JP6577143B2 (es) |
| KR (3) | KR102246124B1 (es) |
| CN (2) | CN113925833A (es) |
| AR (1) | AR107751A1 (es) |
| AU (2) | AU2017227929B2 (es) |
| BR (1) | BR112018069530B1 (es) |
| CA (1) | CA2997859A1 (es) |
| ES (1) | ES2913494T3 (es) |
| HK (1) | HK1258699A1 (es) |
| IL (2) | IL300209A (es) |
| MX (2) | MX2018008754A (es) |
| PL (1) | PL3423059T3 (es) |
| WO (1) | WO2017148837A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA111756C2 (uk) * | 2011-11-03 | 2016-06-10 | Ф. Хоффманн-Ля Рош Аг | Сполуки гетероарилпіридону та азапіридону як інгібітори тирозинкінази брутона |
| EP3423059B1 (en) | 2016-02-29 | 2022-03-23 | F. Hoffmann-La Roche AG | Dosage form compositions comprising an inhibitor of bruton's tyrosine kinase |
| TWI673271B (zh) * | 2016-12-15 | 2019-10-01 | 瑞士商赫孚孟拉羅股份公司 | 製備btk抑制劑之方法 |
| CN108186407B (zh) * | 2018-02-24 | 2019-09-20 | 珀莱雅化妆品股份有限公司 | 一种具有美白抗老功效的固体分散体的制备方法 |
| KR20210119457A (ko) | 2019-01-22 | 2021-10-05 | 에프. 호프만-라 로슈 아게 | 브루톤 티로신 키나제 억제제를 이용한 류마티스 관절염, 만성 자발성 두드러기 및 전신 홍반 루푸스의 치료 방법 |
| WO2021173740A1 (en) | 2020-02-28 | 2021-09-02 | Genentech, Inc. | Methods of treating primary progressive multiple sclerosis using an inhibitor of bruton's tyrosine kinase |
| IL296990A (en) | 2020-04-03 | 2022-12-01 | Genentech Inc | Methods for the treatment of multiple sclerosis relapse using an inhibitor of proton tyrosine kinase |
| CN112577275B (zh) * | 2020-10-30 | 2022-08-12 | 广州迈普再生医学科技股份有限公司 | 一种用于干燥医用高分子材料的洁净工作台 |
| CN113603685A (zh) * | 2021-07-23 | 2021-11-05 | 都创(上海)医药开发有限公司 | Fenebrutinib化合物的晶型及其制备方法和用途 |
| CN115702898B (zh) * | 2021-08-04 | 2024-02-09 | 成都倍特药业股份有限公司 | 一种btk抑制剂固体制剂及其制备方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6287599B1 (en) | 2000-12-20 | 2001-09-11 | Shire Laboratories, Inc. | Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles |
| US7405295B2 (en) | 2003-06-04 | 2008-07-29 | Cgi Pharmaceuticals, Inc. | Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds |
| US7393848B2 (en) | 2003-06-30 | 2008-07-01 | Cgi Pharmaceuticals, Inc. | Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds |
| WO2006053121A2 (en) | 2004-11-10 | 2006-05-18 | Cgi Pharmaceuticals, Inc. | Imidazo[1 , 2-a] pyrazin-8-ylamines useful as modulators of kinase activity |
| KR101357524B1 (ko) | 2005-03-10 | 2014-02-03 | 질레드 코네티컷 인코포레이티드 | 특정 치환된 아미드, 그의 제조 방법, 및 사용 방법 |
| SI1926476T1 (sl) | 2005-08-29 | 2013-07-31 | Sanofi-Aventis U.S. Llc | Amorfne trdne disperzije 7-kloro-N,N,5-trimetil-4-okso-3-fenil-3,5- dihidro-4H-piridazino/4,5-b/indol-1-acetamida |
| EA032466B1 (ru) | 2005-10-07 | 2019-05-31 | Экселиксис, Инк. | Способы получения ингибиторов mek |
| US7838523B2 (en) | 2006-09-11 | 2010-11-23 | Cgi Pharmaceuticals, Inc. | Certain substituted amides, method of making, and method of use thereof |
| AR063946A1 (es) | 2006-09-11 | 2009-03-04 | Cgi Pharmaceuticals Inc | Determinadas pirimidinas sustituidas, el uso de las mismas para el tratamiento de enfermedades mediadas por la inhibicion de la actividad de btk y composiciones farmaceuticas que las comprenden. |
| AR063706A1 (es) | 2006-09-11 | 2009-02-11 | Cgi Pharmaceuticals Inc | Determinadas amidas sustituidas, el uso de las mismas para el tratamiento de enfermedades mediadas por la inhibicion de la actividad de btk y composiciones farmaceuticas que las comprenden. |
| CL2008002793A1 (es) | 2007-09-20 | 2009-09-04 | Cgi Pharmaceuticals Inc | Compuestos derivados de amidas sustituidas, inhibidores de la actividad de btk; composicion farmaceutica que los comprende; utiles en el tratamiento del cancer, trastornos oseos, enfermedades autoinmunes, entre otras |
| WO2009100176A2 (en) | 2008-02-07 | 2009-08-13 | Abbott Laboratories | Pharmaceutical dosage form for oral administration of tyrosine kinase inhibitor |
| ES2554615T3 (es) | 2008-05-06 | 2015-12-22 | Gilead Connecticut, Inc. | Amidas sustituidas, método de preparación y utilización como inhibidores de Btk |
| US8598174B2 (en) | 2008-11-12 | 2013-12-03 | Genetech, Inc. | Pyridazinones, method of making, and method of use thereof |
| TWI540132B (zh) | 2009-06-08 | 2016-07-01 | 亞培公司 | Ｂｃｌ-２族群抑制劑之口服醫藥劑型 |
| ES2573716T3 (es) | 2010-05-07 | 2016-06-09 | Gilead Connecticut, Inc. | Compuestos de piridona y aza-piridona y métodos de utilización |
| CA2800913C (en) | 2010-06-03 | 2019-07-23 | Pharmacyclics, Inc. | The use of inhibitors of bruton's tyrosine kinase (btk) |
| SI2630146T1 (sl) | 2010-10-21 | 2020-12-31 | Medivation Technologies Llc | Kristalinična tosilatna sol (8S,9R)-5-fluoro-8-(4-fluorofenil)-9-(1-metil-1H-1,2,4-triazol-5-IL)- 8,9-dihidro-2H-pirido(4,3,2-DE)ftalazin-3(7H)-ON |
| UA111756C2 (uk) * | 2011-11-03 | 2016-06-10 | Ф. Хоффманн-Ля Рош Аг | Сполуки гетероарилпіридону та азапіридону як інгібітори тирозинкінази брутона |
| AU2012332368A1 (en) | 2011-11-03 | 2014-05-22 | F. Hoffmann-La Roche Ag | Alkylated piperazine compounds as inhibitors of Btk activity |
| EP3423059B1 (en) | 2016-02-29 | 2022-03-23 | F. Hoffmann-La Roche AG | Dosage form compositions comprising an inhibitor of bruton's tyrosine kinase |
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2017
- 2017-02-27 EP EP17707312.9A patent/EP3423059B1/en active Active
- 2017-02-27 KR KR1020187024719A patent/KR102246124B1/ko active IP Right Grant
- 2017-02-27 CN CN202111189630.4A patent/CN113925833A/zh active Pending
- 2017-02-27 KR KR1020207028492A patent/KR102451106B1/ko active IP Right Grant
- 2017-02-27 KR KR1020207028488A patent/KR20200118507A/ko active Application Filing
- 2017-02-27 WO PCT/EP2017/054435 patent/WO2017148837A1/en active Application Filing
- 2017-02-27 JP JP2018521961A patent/JP6577143B2/ja active Active
- 2017-02-27 ES ES17707312T patent/ES2913494T3/es active Active
- 2017-02-27 CA CA2997859A patent/CA2997859A1/en active Pending
- 2017-02-27 MX MX2018008754A patent/MX2018008754A/es unknown
- 2017-02-27 IL IL300209A patent/IL300209A/en unknown
- 2017-02-27 EP EP21217196.1A patent/EP4049660A1/en active Pending
- 2017-02-27 US US15/442,774 patent/US10246461B2/en active Active
- 2017-02-27 BR BR112018069530-0A patent/BR112018069530B1/pt active IP Right Grant
- 2017-02-27 CN CN201780003571.2A patent/CN108367005B/zh active Active
- 2017-02-27 PL PL17707312.9T patent/PL3423059T3/pl unknown
- 2017-02-27 AU AU2017227929A patent/AU2017227929B2/en active Active
- 2017-03-01 AR ARP170100492A patent/AR107751A1/es unknown
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2018
- 2018-07-16 MX MX2022000826A patent/MX2022000826A/es unknown
- 2018-08-20 IL IL261249A patent/IL261249B2/en unknown
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2019
- 2019-01-22 HK HK19101082.6A patent/HK1258699A1/zh unknown
- 2019-02-11 US US16/272,510 patent/US20190177331A1/en not_active Abandoned
- 2019-08-21 JP JP2019151180A patent/JP6876758B2/ja active Active
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2020
- 2020-06-01 US US16/889,308 patent/US11365197B2/en active Active
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2021
- 2021-02-04 JP JP2021016410A patent/JP7258924B2/ja active Active
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2022
- 2022-05-09 US US17/740,131 patent/US20220267340A1/en not_active Abandoned
- 2022-09-29 AU AU2022241561A patent/AU2022241561A1/en active Pending
- 2022-12-20 JP JP2022203410A patent/JP2023036772A/ja active Pending
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2023
- 2023-06-14 US US18/334,515 patent/US20230339957A1/en active Pending
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