MX2020014237A - Metodo para la deteccion y el recuento epigenetico de celulas inmunitarias en muestras de sangre humana para inmunodiagnostico y exploracion neonatal. - Google Patents

Metodo para la deteccion y el recuento epigenetico de celulas inmunitarias en muestras de sangre humana para inmunodiagnostico y exploracion neonatal.

Info

Publication number
MX2020014237A
MX2020014237A MX2020014237A MX2020014237A MX2020014237A MX 2020014237 A MX2020014237 A MX 2020014237A MX 2020014237 A MX2020014237 A MX 2020014237A MX 2020014237 A MX2020014237 A MX 2020014237A MX 2020014237 A MX2020014237 A MX 2020014237A
Authority
MX
Mexico
Prior art keywords
counting
immune cell
immunodiagnostics
cell detection
blood samples
Prior art date
Application number
MX2020014237A
Other languages
English (en)
Inventor
Sven Olek
Original Assignee
Prec For Medicine Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prec For Medicine Gmbh filed Critical Prec For Medicine Gmbh
Publication of MX2020014237A publication Critical patent/MX2020014237A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a métodos mejorados para la detección y el recuento epigenético de células sanguíneas e inmunitarias, y sus respectivos usos y kits.
MX2020014237A 2018-07-05 2019-07-03 Metodo para la deteccion y el recuento epigenetico de celulas inmunitarias en muestras de sangre humana para inmunodiagnostico y exploracion neonatal. MX2020014237A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102018116353.3A DE102018116353B4 (de) 2018-07-05 2018-07-05 Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening
PCT/EP2019/067876 WO2020007928A1 (en) 2018-07-05 2019-07-03 Method for epigenetic immune cell detection and counting in human blood samples for immunodiagnostics and newborn screening

Publications (1)

Publication Number Publication Date
MX2020014237A true MX2020014237A (es) 2021-05-27

Family

ID=67514540

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020014237A MX2020014237A (es) 2018-07-05 2019-07-03 Metodo para la deteccion y el recuento epigenetico de celulas inmunitarias en muestras de sangre humana para inmunodiagnostico y exploracion neonatal.

Country Status (11)

Country Link
EP (1) EP3818178A1 (es)
CN (1) CN112400027A (es)
BR (1) BR112020026951A2 (es)
CA (1) CA3105679A1 (es)
CL (1) CL2021000002A1 (es)
CO (1) CO2020016598A2 (es)
DE (1) DE102018116353B4 (es)
EC (1) ECSP20084782A (es)
MX (1) MX2020014237A (es)
PE (1) PE20210631A1 (es)
WO (1) WO2020007928A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116949156B (zh) * 2023-09-19 2023-12-08 美迪西普亚医药科技(上海)有限公司 一种基于核酸变体的通用型检测人t细胞的分析方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2199411B1 (en) * 2008-12-16 2015-05-06 Epiontis GmbH Epigenetic markers for the identification of CD3 positive T-lymphocytes
US20170233807A1 (en) * 2008-12-16 2017-08-17 Epiontis Gmbh Epigenetic Markers for the Identification of Blood Sub-cells of Type 1
JP6010037B2 (ja) * 2010-10-08 2016-10-19 エピオンティス ゲーエムベーハー 腫瘍浸潤全ｔリンパ球の分析に基づいて、がん患者の生存指標を測定する方法
US20130296328A1 (en) * 2011-01-20 2013-11-07 Université Libre de Bruxelles Epigenetic portraits of human breast cancers
EP2788510B1 (en) * 2012-03-12 2016-12-14 Epiontis GmbH Epigenetic marker for the identification of cd3cd4 positive t lymphocytes
GB201221133D0 (en) * 2012-11-23 2013-01-09 Epiontis Gmbh Epigenetic method for the identification of subpopulations of CD8 and T lympocytes, in particular CD8 alpha and beta T lymphocytes
US10208346B2 (en) * 2013-04-19 2019-02-19 Epiontis Gmbh Method for identifying the quantitative cellular composition in a biological sample
GB201516972D0 (en) * 2015-09-25 2015-11-11 Epiontis Gmbh LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells
GB201516971D0 (en) * 2015-09-25 2015-11-11 Epiontis Gmbh MVD as epigenetic marker for the identification of immune cells, in particular CD56+ NK cells

Also Published As

Publication number Publication date
US20220090196A1 (en) 2022-03-24
ECSP20084782A (es) 2021-05-31
PE20210631A1 (es) 2021-03-23
DE102018116353B4 (de) 2020-06-10
EP3818178A1 (en) 2021-05-12
CL2021000002A1 (es) 2021-07-30
BR112020026951A2 (pt) 2021-04-13
WO2020007928A1 (en) 2020-01-09
DE102018116353A1 (de) 2020-01-09
CA3105679A1 (en) 2020-01-09
CO2020016598A2 (es) 2021-03-19
CN112400027A (zh) 2021-02-23

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