MX2020005563A - Compuesto de tieno[3,2-d]pirimidina que tiene actividad inhibidora para proteina cinasa. - Google Patents

Compuesto de tieno[3,2-d]pirimidina que tiene actividad inhibidora para proteina cinasa.

Info

Publication number
MX2020005563A
MX2020005563A MX2020005563A MX2020005563A MX2020005563A MX 2020005563 A MX2020005563 A MX 2020005563A MX 2020005563 A MX2020005563 A MX 2020005563A MX 2020005563 A MX2020005563 A MX 2020005563A MX 2020005563 A MX2020005563 A MX 2020005563A
Authority
MX
Mexico
Prior art keywords
thieno
inhibitory activity
protein kinase
pyrimidine compound
amino
Prior art date
Application number
MX2020005563A
Other languages
English (en)
Inventor
In Hwan Bae
Young Gil Ahn
Kwee Hyun Suh
Seung Hyun Jung
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of MX2020005563A publication Critical patent/MX2020005563A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Abstract

La presente invención se relaciona con un compuesto, 4-amino-N-(1-((3-cloro-2-fluoro-4-hidroxifenil)amino)-6-metilisoq uinolin-5-il)tieno[3,2-d]pirimidino-7-carboxamida y sales farmacéuticamente aceptables del mismo que tienen actividad inhibidora para proteína cinasas.
MX2020005563A 2017-11-30 2018-11-29 Compuesto de tieno[3,2-d]pirimidina que tiene actividad inhibidora para proteina cinasa. MX2020005563A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762592679P 2017-11-30 2017-11-30
PCT/KR2018/014997 WO2019107987A1 (en) 2017-11-30 2018-11-29 THIENO[3,2-d]PYRIMIDINE COMPOUND HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE

Publications (1)

Publication Number Publication Date
MX2020005563A true MX2020005563A (es) 2020-10-28

Family

ID=66665192

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020005563A MX2020005563A (es) 2017-11-30 2018-11-29 Compuesto de tieno[3,2-d]pirimidina que tiene actividad inhibidora para proteina cinasa.

Country Status (12)

Country Link
US (2) US11492357B2 (es)
EP (1) EP3717492B1 (es)
JP (1) JP7096333B2 (es)
KR (1) KR20200084899A (es)
CN (1) CN111542529B (es)
AU (1) AU2018375456B2 (es)
BR (1) BR112020010905A2 (es)
CA (1) CA3084074C (es)
IL (1) IL274963A (es)
MX (1) MX2020005563A (es)
TW (1) TWI803541B (es)
WO (1) WO2019107987A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117677398A (zh) 2021-07-27 2024-03-08 东丽株式会社 用于癌的治疗和/或预防的药品

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7560552B2 (en) * 2002-03-21 2009-07-14 Abbott Laboratories Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
TW200526204A (en) * 2004-02-03 2005-08-16 Pharmacia Italia Spa 1h-thieno[2,3-c]pyrazole derivatives useful as kinase inhibitors
KR101094446B1 (ko) * 2009-11-19 2011-12-15 한국과학기술연구원 단백질 키나아제 저해활성을 가지는 2,4,7-치환된 티에노［3,2-ｄ］피리미딘 화합물
KR101483215B1 (ko) 2010-01-29 2015-01-16 한미약품 주식회사 단백질 키나아제 저해활성을 갖는 비시클릭 헤테로아릴 유도체
WO2012007375A1 (en) * 2010-07-13 2012-01-19 F. Hoffmann-La Roche Ag Pyrazolo [1, 5a] pyrimidine and thieno [3, 2b] pyrimidine derivatives as irak4 modulators
EP3617213A1 (en) * 2011-12-30 2020-03-04 Hanmi Pharm. Co., Ltd. Thieno[3,2-d]pyrimidine derivatives having inhibitory activity for protein kinases
CN104159904B (zh) * 2012-01-10 2016-12-14 霍夫曼-拉罗奇有限公司 噻吩并嘧啶化合物
KR20140011780A (ko) * 2012-07-19 2014-01-29 한미약품 주식회사 단백질 키나아제 저해활성을 갖는 이소퀴놀린-5-카복스아미드 유도체

Also Published As

Publication number Publication date
CA3084074C (en) 2023-03-21
CN111542529A (zh) 2020-08-14
US20200308188A1 (en) 2020-10-01
KR20200084899A (ko) 2020-07-13
WO2019107987A1 (en) 2019-06-06
CN111542529B (zh) 2023-06-30
AU2018375456B2 (en) 2021-11-18
JP7096333B2 (ja) 2022-07-05
US11492357B2 (en) 2022-11-08
JP2021504434A (ja) 2021-02-15
EP3717492A4 (en) 2021-06-02
TWI803541B (zh) 2023-06-01
EP3717492A1 (en) 2020-10-07
US20230060973A1 (en) 2023-03-02
EP3717492B1 (en) 2023-05-24
AU2018375456A1 (en) 2020-06-25
TW201925208A (zh) 2019-07-01
CA3084074A1 (en) 2019-06-06
BR112020010905A2 (pt) 2020-11-17
IL274963A (en) 2020-07-30

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