MX2019001469A - Tratamiento del cáncer usando un receptor de antígeno quimérico en combinación con un inhibidor de una molécula de macrófago pro- m2. - Google Patents
Tratamiento del cáncer usando un receptor de antígeno quimérico en combinación con un inhibidor de una molécula de macrófago pro- m2.Info
- Publication number
- MX2019001469A MX2019001469A MX2019001469A MX2019001469A MX2019001469A MX 2019001469 A MX2019001469 A MX 2019001469A MX 2019001469 A MX2019001469 A MX 2019001469A MX 2019001469 A MX2019001469 A MX 2019001469A MX 2019001469 A MX2019001469 A MX 2019001469A
- Authority
- MX
- Mexico
- Prior art keywords
- pro
- inhibitor
- combination
- cancer
- treatment
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 210000004322 M2 macrophage Anatomy 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000001565 modulated differential scanning calorimetry Methods 0.000 abstract 1
- 210000004985 myeloid-derived suppressor cell Anatomy 0.000 abstract 1
Classifications
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Abstract
La invención proporciona invenciones y métodos para el tratamiento de enfermedades asociadas con la expresión de un antígeno, por ejemplo, un antígeno de tumo sólido o antígeno expresado en un tumor asociado con TAM y/o MDSC, mediante la administración de un linfocito T recombinante que comprende un CAR que se une a dicho antígeno, como se describe en el presente documento, en combinación con un inhibidor de una molécula de macrófago pro-M2, por ejemplo, descrita en el presente documento. La invención también proporciona kits y composiciones descritas en el presente documento.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662369589P | 2016-08-01 | 2016-08-01 | |
PCT/US2017/044909 WO2018026819A2 (en) | 2016-08-01 | 2017-08-01 | Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule |
Publications (1)
Publication Number | Publication Date |
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MX2019001469A true MX2019001469A (es) | 2019-10-02 |
Family
ID=59684040
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019001469A MX2019001469A (es) | 2016-08-01 | 2017-08-01 | Tratamiento del cáncer usando un receptor de antígeno quimérico en combinación con un inhibidor de una molécula de macrófago pro- m2. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20190161542A1 (es) |
EP (1) | EP3490590A2 (es) |
JP (2) | JP2019527696A (es) |
KR (1) | KR20190036551A (es) |
CN (1) | CN110267677A (es) |
AU (1) | AU2017306267A1 (es) |
BR (1) | BR112019002035A2 (es) |
CA (1) | CA3032581A1 (es) |
IL (1) | IL264588A (es) |
MX (1) | MX2019001469A (es) |
RU (1) | RU2019105693A (es) |
SG (1) | SG11201900885VA (es) |
WO (1) | WO2018026819A2 (es) |
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-
2017
- 2017-08-01 CA CA3032581A patent/CA3032581A1/en active Pending
- 2017-08-01 KR KR1020197006125A patent/KR20190036551A/ko not_active Application Discontinuation
- 2017-08-01 EP EP17755330.2A patent/EP3490590A2/en active Pending
- 2017-08-01 BR BR112019002035-7A patent/BR112019002035A2/pt not_active Application Discontinuation
- 2017-08-01 MX MX2019001469A patent/MX2019001469A/es unknown
- 2017-08-01 SG SG11201900885VA patent/SG11201900885VA/en unknown
- 2017-08-01 RU RU2019105693A patent/RU2019105693A/ru unknown
- 2017-08-01 CN CN201780057831.4A patent/CN110267677A/zh active Pending
- 2017-08-01 AU AU2017306267A patent/AU2017306267A1/en not_active Abandoned
- 2017-08-01 US US16/322,285 patent/US20190161542A1/en active Pending
- 2017-08-01 WO PCT/US2017/044909 patent/WO2018026819A2/en unknown
- 2017-08-01 JP JP2019505190A patent/JP2019527696A/ja not_active Withdrawn
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2019
- 2019-01-31 IL IL264588A patent/IL264588A/en unknown
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2022
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Also Published As
Publication number | Publication date |
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KR20190036551A (ko) | 2019-04-04 |
RU2019105693A (ru) | 2020-09-01 |
AU2017306267A1 (en) | 2019-02-14 |
CA3032581A1 (en) | 2018-02-08 |
EP3490590A2 (en) | 2019-06-05 |
RU2019105693A3 (es) | 2021-04-26 |
JP2022062040A (ja) | 2022-04-19 |
IL264588A (en) | 2019-02-28 |
SG11201900885VA (en) | 2019-02-27 |
JP2019527696A (ja) | 2019-10-03 |
CN110267677A (zh) | 2019-09-20 |
WO2018026819A2 (en) | 2018-02-08 |
WO2018026819A3 (en) | 2018-03-08 |
BR112019002035A2 (pt) | 2019-05-14 |
US20190161542A1 (en) | 2019-05-30 |
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