MX2015013703A - Mitigacion e inversion de la fibrosis e inflamacion mediante la inhibicion de la funcion de tl1a y vias de señalizacion relacionadas. - Google Patents

Mitigacion e inversion de la fibrosis e inflamacion mediante la inhibicion de la funcion de tl1a y vias de señalizacion relacionadas.

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Publication number
MX2015013703A
MX2015013703A MX2015013703A MX2015013703A MX2015013703A MX 2015013703 A MX2015013703 A MX 2015013703A MX 2015013703 A MX2015013703 A MX 2015013703A MX 2015013703 A MX2015013703 A MX 2015013703A MX 2015013703 A MX2015013703 A MX 2015013703A
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MX
Mexico
Prior art keywords
tl1a
inflammation
treating fibrosis
inhibiting
individual
Prior art date
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MX2015013703A
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English (en)
Inventor
Q Shih David
R Targan Stephan
Li Dalin
Bilsborough Janine
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Cedars Sinai Medical Center
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51625529&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2015013703(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cedars Sinai Medical Center filed Critical Cedars Sinai Medical Center
Publication of MX2015013703A publication Critical patent/MX2015013703A/es

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Abstract

La presente invención se refiere a métodos para tratar de la fibrosis y enfermedad inflamatoria intestinal. En una modalidad, la presente invención trata la inflamación intestinal administrando una dosificación terapéuticamente efectiva de inhibidores de TL1A y/o inhibidores de DR3 a un individuo. En otra modalidad, la presente invención proporciona un método para revertir la fibrosis de tejido en un individuo inhibiendo la función de señalización de TL1A-DR3.
MX2015013703A 2013-03-27 2014-03-27 Mitigacion e inversion de la fibrosis e inflamacion mediante la inhibicion de la funcion de tl1a y vias de señalizacion relacionadas. MX2015013703A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361805806P 2013-03-27 2013-03-27
US201361872020P 2013-08-30 2013-08-30
PCT/US2014/032054 WO2014160883A1 (en) 2013-03-27 2014-03-27 Treating fibrosis and inflammation by inhibiting tl1a

Publications (1)

Publication Number Publication Date
MX2015013703A true MX2015013703A (es) 2016-08-11

Family

ID=51625529

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015013703A MX2015013703A (es) 2013-03-27 2014-03-27 Mitigacion e inversion de la fibrosis e inflamacion mediante la inhibicion de la funcion de tl1a y vias de señalizacion relacionadas.

Country Status (11)

Country Link
US (3) US10633449B2 (es)
EP (3) EP3639841B1 (es)
JP (3) JP6671276B2 (es)
KR (3) KR20230109779A (es)
CN (2) CN112870368A (es)
AU (1) AU2014241162A1 (es)
BR (1) BR112015024752A2 (es)
CA (1) CA2908553A1 (es)
CL (1) CL2015002866A1 (es)
MX (1) MX2015013703A (es)
WO (1) WO2014160883A1 (es)

Families Citing this family (11)

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WO2010062960A2 (en) 2008-11-26 2010-06-03 Cedars-Sinai Medical Center METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE
CN104114577A (zh) 2011-09-30 2014-10-22 特瓦制药澳大利亚私人有限公司 针对TL1a的抗体及其用途
EP3639841B1 (en) 2013-03-27 2023-09-06 Cedars-Sinai Medical Center Treating fibrosis by inhibiting tl1a
US10316083B2 (en) 2013-07-19 2019-06-11 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
CN104745587B (zh) * 2015-01-05 2017-07-21 西安交通大学医学院第一附属医院 用于识别***生长因子的核酸适配子及其应用
EP3294336A1 (en) * 2015-05-15 2018-03-21 Cedars-Sinai Medical Center Models, methods and compositions for treating inflammatory bowel disease
TWI703158B (zh) 2015-09-18 2020-09-01 美商希佛隆公司 特異性結合tl1a之抗體
US11186872B2 (en) 2016-03-17 2021-11-30 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2
US10093731B2 (en) 2017-02-24 2018-10-09 Kindred Biosciences, Inc. Anti-IL31 antibodies for veterinary use
JP2023530046A (ja) * 2020-04-02 2023-07-13 ラ ホヤ インスティテュート フォー イムノロジー Ｔｎｆファミリーのメンバーの二重標的化のための方法および組合せ
CA3180632A1 (en) * 2020-06-03 2021-12-09 Cedars-Sinai Medical Center Methods and systems for measuring post-operative disease recurrence

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