MX2013000733A - Composiciones de noribogaina. - Google Patents

Composiciones de noribogaina.

Info

Publication number
MX2013000733A
MX2013000733A MX2013000733A MX2013000733A MX2013000733A MX 2013000733 A MX2013000733 A MX 2013000733A MX 2013000733 A MX2013000733 A MX 2013000733A MX 2013000733 A MX2013000733 A MX 2013000733A MX 2013000733 A MX2013000733 A MX 2013000733A
Authority
MX
Mexico
Prior art keywords
noribogaine
compositions
noribogaine compositions
enantiomer
disclosed
Prior art date
Application number
MX2013000733A
Other languages
English (en)
Inventor
Robert M Moriarty
Deborah C Mash
Original Assignee
Demerx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Demerx Inc filed Critical Demerx Inc
Publication of MX2013000733A publication Critical patent/MX2013000733A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Abstract

Se dan a conocer composiciones de noribogaína que comprenden un nivel muy alto del enantiómero 2(R), 4(S), 5(S), 6(S) y 18(R) y no más de 0.5% en peso de ibogaína en relación con la cantidad total de noribogaína.
MX2013000733A 2010-07-23 2011-07-22 Composiciones de noribogaina. MX2013000733A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36731010P 2010-07-23 2010-07-23
US41976610P 2010-12-03 2010-12-03
PCT/US2011/045081 WO2012012764A1 (en) 2010-07-23 2011-07-22 Noribogaine compositions

Publications (1)

Publication Number Publication Date
MX2013000733A true MX2013000733A (es) 2013-05-30

Family

ID=44558453

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013000733A MX2013000733A (es) 2010-07-23 2011-07-22 Composiciones de noribogaina.

Country Status (9)

Country Link
US (3) US9358237B2 (es)
EP (1) EP2595632A1 (es)
JP (2) JP6049615B2 (es)
CN (1) CN103079571A (es)
CA (1) CA2806232A1 (es)
MX (1) MX2013000733A (es)
RU (1) RU2586296C2 (es)
UA (1) UA111065C2 (es)
WO (1) WO2012012764A1 (es)

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US9591978B2 (en) 2014-03-13 2017-03-14 Demerx, Inc. Methods and compositions for pre-screening patients for treatment with noribogaine
WO2015142346A1 (en) * 2014-03-20 2015-09-24 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
CA2989550C (en) 2014-06-18 2023-08-08 Demerx, Inc. Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them
US9549935B2 (en) 2014-07-14 2017-01-24 Demerx, Inc. Methods and compositions for treating migraines using noribogaine
WO2016086194A1 (en) 2014-11-26 2016-06-02 Demerx, Inc. Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids
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Also Published As

Publication number Publication date
UA111065C2 (uk) 2016-03-25
JP6267776B2 (ja) 2018-01-24
US9358237B2 (en) 2016-06-07
US20210275538A1 (en) 2021-09-09
RU2586296C2 (ru) 2016-06-10
WO2012012764A1 (en) 2012-01-26
JP2017061532A (ja) 2017-03-30
RU2013102923A (ru) 2014-08-27
US20130131046A1 (en) 2013-05-23
CN103079571A (zh) 2013-05-01
EP2595632A1 (en) 2013-05-29
JP2013532663A (ja) 2013-08-19
US20190262351A1 (en) 2019-08-29
JP6049615B2 (ja) 2016-12-21
CA2806232A1 (en) 2012-01-26

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