MX2010005397A - Anticuerpo monoclonal capaz de unirse a anexelekto, y uso del mismo. - Google Patents

Anticuerpo monoclonal capaz de unirse a anexelekto, y uso del mismo.

Info

Publication number
MX2010005397A
MX2010005397A MX2010005397A MX2010005397A MX2010005397A MX 2010005397 A MX2010005397 A MX 2010005397A MX 2010005397 A MX2010005397 A MX 2010005397A MX 2010005397 A MX2010005397 A MX 2010005397A MX 2010005397 A MX2010005397 A MX 2010005397A
Authority
MX
Mexico
Prior art keywords
anexelekto
binding
monoclonal antibody
antibody capable
activity
Prior art date
Application number
MX2010005397A
Other languages
English (en)
Inventor
Takehisa Kitazawa
Tsukasa Suzuki
Shigehisa Nagahashi
Hajime Miyamoto
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40638811&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2010005397(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of MX2010005397A publication Critical patent/MX2010005397A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0331—Animal model for proliferative diseases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Abstract

Un anticuerpo anti-AXL con una función específica puede ser obtenido con éxito. Se encuentra que el anticuerpo tiene una actividad anti-angiogénesis y una actividad antitumoral. Los anticuerpos anti-AXL son útiles como inhibidores de la angiogénesis y agentes para inducir o inhibir la actividad de fosforilación.
MX2010005397A 2007-11-15 2008-11-14 Anticuerpo monoclonal capaz de unirse a anexelekto, y uso del mismo. MX2010005397A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007297168 2007-11-15
PCT/JP2008/070739 WO2009063965A1 (ja) 2007-11-15 2008-11-14 Anexelektoに結合するモノクローナル抗体、およびその利用

Publications (1)

Publication Number Publication Date
MX2010005397A true MX2010005397A (es) 2010-10-04

Family

ID=40638811

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005397A MX2010005397A (es) 2007-11-15 2008-11-14 Anticuerpo monoclonal capaz de unirse a anexelekto, y uso del mismo.

Country Status (18)

Country Link
US (2) US9175091B2 (es)
EP (2) EP2853544A1 (es)
JP (2) JP5554993B2 (es)
KR (1) KR101568051B1 (es)
CN (1) CN101918452A (es)
AR (1) AR069333A1 (es)
AU (1) AU2008321835B2 (es)
BR (1) BRPI0820543A2 (es)
CA (1) CA2706549A1 (es)
CL (1) CL2008003416A1 (es)
IL (1) IL205545A0 (es)
MX (1) MX2010005397A (es)
PE (1) PE20091024A1 (es)
RU (1) RU2559530C2 (es)
SG (1) SG188134A1 (es)
TW (1) TW200936160A (es)
WO (1) WO2009063965A1 (es)
ZA (1) ZA201003496B (es)

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EP2275443B1 (en) 2008-04-11 2015-12-02 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
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EP2409991B1 (en) 2009-03-19 2017-05-03 Chugai Seiyaku Kabushiki Kaisha Antibody constant region variant
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GB201410826D0 (en) 2014-06-18 2014-07-30 Bergenbio As Anti-axl antibodies
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Also Published As

Publication number Publication date
AU2008321835B2 (en) 2014-11-20
JP5554993B2 (ja) 2014-07-23
IL205545A0 (en) 2010-12-30
CN101918452A (zh) 2010-12-15
JP2014224116A (ja) 2014-12-04
AR069333A1 (es) 2010-01-13
AU2008321835A1 (en) 2009-05-22
EP2228392A4 (en) 2012-05-02
CA2706549A1 (en) 2009-05-22
CL2008003416A1 (es) 2009-10-30
BRPI0820543A2 (pt) 2015-06-16
RU2559530C2 (ru) 2015-08-10
US9175091B2 (en) 2015-11-03
US20160053019A1 (en) 2016-02-25
US20110044984A1 (en) 2011-02-24
RU2010123916A (ru) 2011-12-20
WO2009063965A1 (ja) 2009-05-22
KR101568051B1 (ko) 2015-11-10
EP2853544A1 (en) 2015-04-01
JPWO2009063965A1 (ja) 2011-03-31
KR20100097688A (ko) 2010-09-03
EP2228392A1 (en) 2010-09-15
SG188134A1 (en) 2013-03-28
TW200936160A (en) 2009-09-01
PE20091024A1 (es) 2009-08-12
ZA201003496B (en) 2011-08-31

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