MX2007004215A - Proceso para la sintesis de 4-(3-metansulfonilfenil)-1-n- propilpiperidina. - Google Patents

Proceso para la sintesis de 4-(3-metansulfonilfenil)-1-n- propilpiperidina.

Info

Publication number
MX2007004215A
MX2007004215A MX2007004215A MX2007004215A MX2007004215A MX 2007004215 A MX2007004215 A MX 2007004215A MX 2007004215 A MX2007004215 A MX 2007004215A MX 2007004215 A MX2007004215 A MX 2007004215A MX 2007004215 A MX2007004215 A MX 2007004215A
Authority
MX
Mexico
Prior art keywords
methanesulfonylphenyl
piperidine
propyl
synthesis
formula
Prior art date
Application number
MX2007004215A
Other languages
English (en)
Inventor
Richard Desmond
Paul N Devine
Donald R Gauthier
Original Assignee
Neurosearch Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch Sweden Ab filed Critical Neurosearch Sweden Ab
Publication of MX2007004215A publication Critical patent/MX2007004215A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/24—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by sulfur atoms to which a second hetero atom is attached

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion se dirige al proceso para la preparacion de 4-(3-metansulfonil)-1-n-propilpiperidina (I), o una sal aceptada para uso farmaceutico de esta, el cual consiste en: oxidar un sulfuro de la formula (II), con un agente oxidante catalitico y un oxidante para obtener un compuesto de formula (III), seguido por la reduccion catalitica del compuesto de la formula (III).
MX2007004215A 2004-10-13 2005-10-13 Proceso para la sintesis de 4-(3-metansulfonilfenil)-1-n- propilpiperidina. MX2007004215A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61819604P 2004-10-13 2004-10-13
PCT/EP2005/011020 WO2006040155A1 (en) 2004-10-13 2005-10-13 Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine

Publications (1)

Publication Number Publication Date
MX2007004215A true MX2007004215A (es) 2007-12-12

Family

ID=35478927

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007004215A MX2007004215A (es) 2004-10-13 2005-10-13 Proceso para la sintesis de 4-(3-metansulfonilfenil)-1-n- propilpiperidina.

Country Status (15)

Country Link
US (1) US7923459B2 (es)
EP (1) EP1802573B1 (es)
JP (1) JP4891908B2 (es)
KR (1) KR101319235B1 (es)
CN (1) CN101056854B (es)
AU (1) AU2005293754B2 (es)
CA (1) CA2584831C (es)
DK (1) DK1802573T3 (es)
ES (1) ES2659577T3 (es)
HK (1) HK1105195A1 (es)
HU (1) HUE029790T2 (es)
MX (1) MX2007004215A (es)
NZ (1) NZ555094A (es)
PL (1) PL1802573T3 (es)
WO (1) WO2006040155A1 (es)

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EP3096759B1 (en) 2014-01-22 2022-04-06 Prilenia Neurotherapeutics Ltd. Modified release formulations of pridopidine
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WO2016106142A1 (en) * 2014-12-22 2016-06-30 Teva Pharmaceuticals International Gmbh L-tartrate salt of pridopidine
CA2977264C (en) 2015-02-25 2021-12-07 Teva Pharmaceuticals International Gmbh Use of pridopidine to improve cognitive function and for treating alzheimer's disease
US11471449B2 (en) 2015-02-25 2022-10-18 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
AR105434A1 (es) * 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina
US11738012B2 (en) 2016-02-24 2023-08-29 Prilenia Neurotherapeutics Ltd. Treatment of neurodegenerative eye disease using pridopidine
JP7278210B2 (ja) 2016-08-24 2023-05-19 プリレニア ニューロセラピューティクス リミテッド ジストニアを治療するためのプリドピジンの使用
MX2019002265A (es) 2016-08-24 2019-10-30 Prilenia Therapeutics Dev Ltd Uso de pridopidina para el tratamiento de la disminucion funcional.
DK3512506T3 (da) 2016-09-16 2022-04-19 Prilenia Neurotherapeutics Ltd Anvendelse af pridopidin til behandling af retts syndrom
CN110505902B (zh) 2017-01-20 2022-11-11 普瑞尼亚神经治疗有限公司 普利多匹定用于治疗脆性x综合征的应用
EP3357909A1 (en) 2017-02-02 2018-08-08 Sandoz AG Crystalline 4-[3-(methylsulfonyl)phenyl]-1-propyl-piperidine
FI3668509T3 (fi) 2017-08-14 2023-03-14 Prilenia Neurotherapeutics Ltd Menetelmä hoitaa amyotrofista lateraaliskleroosia pridopidiinilla
BR112020004045A2 (pt) 2017-08-30 2020-09-01 Prilenia Neurotherapeutics Ltd. formas de dosagem de elevada concentração de pridopidina
MX2020002645A (es) 2017-09-08 2021-06-10 Prilenia Neurotherapeutics Ltd Pridopidina para el tratamiento de las discinesias inducidas por fármacos.

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Also Published As

Publication number Publication date
ES2659577T3 (es) 2018-03-16
NZ555094A (en) 2009-07-31
US20070238879A1 (en) 2007-10-11
EP1802573A1 (en) 2007-07-04
KR20070065911A (ko) 2007-06-25
DK1802573T3 (en) 2016-12-19
WO2006040155A1 (en) 2006-04-20
AU2005293754B2 (en) 2011-07-21
KR101319235B1 (ko) 2013-10-16
AU2005293754A1 (en) 2006-04-20
CN101056854B (zh) 2013-06-05
JP4891908B2 (ja) 2012-03-07
EP1802573B1 (en) 2016-09-28
PL1802573T3 (pl) 2017-03-31
JP2008515951A (ja) 2008-05-15
US7923459B2 (en) 2011-04-12
HK1105195A1 (zh) 2008-02-06
HUE029790T2 (hu) 2017-04-28
CA2584831C (en) 2013-09-17
CN101056854A (zh) 2007-10-17
CA2584831A1 (en) 2006-04-20

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