MD3680243T2 - Compus pentaciclic - Google Patents
Compus pentaciclicInfo
- Publication number
- MD3680243T2 MD3680243T2 MDE20200725T MDE20200725T MD3680243T2 MD 3680243 T2 MD3680243 T2 MD 3680243T2 MD E20200725 T MDE20200725 T MD E20200725T MD E20200725 T MDE20200725 T MD E20200725T MD 3680243 T2 MD3680243 T2 MD 3680243T2
- Authority
- MD
- Moldova
- Prior art keywords
- pentacyclic compound
- pentacyclic
- compound
- formulas
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Prezenta invenţie oferă compuşi reprezentaţi de formulele (I)-(VI) sau săruri acceptabile din punct de vedere farmaceutic ale acestora:
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017172169 | 2017-09-07 | ||
| PCT/JP2018/032797 WO2019049869A1 (ja) | 2017-09-07 | 2018-09-05 | 五環式化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD3680243T2 true MD3680243T2 (ro) | 2022-05-31 |
Family
ID=65517037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDE20200725T MD3680243T2 (ro) | 2017-09-07 | 2018-09-05 | Compus pentaciclic |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US10239889B1 (ro) |
| EP (1) | EP3680243B1 (ro) |
| JP (1) | JP6557441B1 (ro) |
| KR (1) | KR102307738B1 (ro) |
| CN (1) | CN111051316B (ro) |
| AR (1) | AR112788A1 (ro) |
| AU (1) | AU2018330578B2 (ro) |
| BR (1) | BR112020003197A2 (ro) |
| CA (1) | CA3072740A1 (ro) |
| CL (1) | CL2020000376A1 (ro) |
| CO (1) | CO2020001471A2 (ro) |
| CY (1) | CY1125355T1 (ro) |
| DK (1) | DK3680243T3 (ro) |
| ES (1) | ES2903172T3 (ro) |
| HR (1) | HRP20220019T1 (ro) |
| HU (1) | HUE056791T2 (ro) |
| IL (1) | IL272652B (ro) |
| JO (1) | JOP20200030A1 (ro) |
| LT (1) | LT3680243T (ro) |
| MA (1) | MA50093B1 (ro) |
| MD (1) | MD3680243T2 (ro) |
| MX (1) | MX2020001786A (ro) |
| PH (1) | PH12020500341A1 (ro) |
| PL (1) | PL3680243T3 (ro) |
| PT (1) | PT3680243T (ro) |
| RS (1) | RS62796B1 (ro) |
| RU (1) | RU2754557C1 (ro) |
| SG (1) | SG11202001240XA (ro) |
| SI (1) | SI3680243T1 (ro) |
| TW (1) | TWI707859B (ro) |
| UA (1) | UA125940C2 (ro) |
| WO (1) | WO2019049869A1 (ro) |
| ZA (1) | ZA202000970B (ro) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020533317A (ja) | 2017-09-07 | 2020-11-19 | オーガスタ ユニバーシティ リサーチ インスティテュート，インコーポレーテッド | 特異的ａｋｔ３活性化剤およびその使用 |
| CN109467538A (zh) | 2017-09-07 | 2019-03-15 | 和记黄埔医药（上海）有限公司 | 环烯烃取代的杂芳环类化合物及其用途 |
| WO2020179781A1 (ja) * | 2019-03-05 | 2020-09-10 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 五環式化合物の塩およびそれらの結晶 |
| JPWO2020179780A1 (ro) | 2019-03-05 | 2020-09-10 | ||
| WO2021113492A1 (en) * | 2019-12-06 | 2021-06-10 | Schrödinger, Inc. | Cyclic compounds and methods of using same |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4187306A (en) * | 1977-07-26 | 1980-02-05 | Bayer Aktiengesellschaft | Benzodiazepine-diones, a process for their production and their use as medicaments |
| DD258234A1 (de) * | 1987-03-05 | 1988-07-13 | Univ Leipzig | Verfahren zur herstellung von pyrido/3',2':4,5/thieno/2,3-e/imidazo-/1,2-c/pyrimidinen sowie strukturanaloger -pyrimido/1,2-c/pyrimidine bzw. -1,3-diazepino/1,2-c/pyrimidine |
| RU2117670C1 (ru) * | 1988-10-31 | 1998-08-20 | Эйсай Ко., Лтд. | Производные триазоло[1,4]диазепина и способы их получения |
| TW197442B (ro) * | 1990-02-08 | 1993-01-01 | Pfizer | |
| KR100203456B1 (ko) * | 1995-06-20 | 1999-06-15 | 한승수 | 디하이드로에보디아민-에이치씨1를 유효성분으로 함유하는 알츠하이머병에 의한 치매 치료제 |
| FR2779652B1 (fr) * | 1998-06-15 | 2001-06-08 | Sod Conseils Rech Applic | Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique |
| JP4751398B2 (ja) * | 2004-10-20 | 2011-08-17 | エフ．ホフマン−ラ ロシュ アーゲー | ハロゲン置換ベンゾジアゼピン誘導体 |
| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
| US8192080B2 (en) | 2007-01-23 | 2012-06-05 | Tsi Technologies Llc | Microwire-controlled autoclave and method |
-
2018
- 2018-09-05 US US16/122,116 patent/US10239889B1/en active Active
- 2018-09-05 SG SG11202001240XA patent/SG11202001240XA/en unknown
- 2018-09-05 RU RU2020106798A patent/RU2754557C1/ru active
- 2018-09-05 ES ES18853415T patent/ES2903172T3/es active Active
- 2018-09-05 PL PL18853415T patent/PL3680243T3/pl unknown
- 2018-09-05 PT PT188534150T patent/PT3680243T/pt unknown
- 2018-09-05 MA MA50093A patent/MA50093B1/fr unknown
- 2018-09-05 BR BR112020003197-6A patent/BR112020003197A2/pt unknown
- 2018-09-05 HU HUE18853415A patent/HUE056791T2/hu unknown
- 2018-09-05 EP EP18853415.0A patent/EP3680243B1/en active Active
- 2018-09-05 MX MX2020001786A patent/MX2020001786A/es unknown
- 2018-09-05 CA CA3072740A patent/CA3072740A1/en active Pending
- 2018-09-05 HR HRP20220019TT patent/HRP20220019T1/hr unknown
- 2018-09-05 IL IL272652A patent/IL272652B/en unknown
- 2018-09-05 JO JOP/2020/0030A patent/JOP20200030A1/ar unknown
- 2018-09-05 AR ARP180102517A patent/AR112788A1/es unknown
- 2018-09-05 LT LTEPPCT/JP2018/032797T patent/LT3680243T/lt unknown
- 2018-09-05 JP JP2019516726A patent/JP6557441B1/ja active Active
- 2018-09-05 SI SI201830467T patent/SI3680243T1/sl unknown
- 2018-09-05 MD MDE20200725T patent/MD3680243T2/ro unknown
- 2018-09-05 UA UAA202000934A patent/UA125940C2/uk unknown
- 2018-09-05 CN CN201880053052.1A patent/CN111051316B/zh active Active
- 2018-09-05 RS RS20220015A patent/RS62796B1/sr unknown
- 2018-09-05 TW TW107131095A patent/TWI707859B/zh active
- 2018-09-05 DK DK18853415.0T patent/DK3680243T3/da active
- 2018-09-05 KR KR1020207004232A patent/KR102307738B1/ko active IP Right Grant
- 2018-09-05 WO PCT/JP2018/032797 patent/WO2019049869A1/ja unknown
- 2018-09-05 AU AU2018330578A patent/AU2018330578B2/en active Active
-
2020
- 2020-02-11 CO CONC2020/0001471A patent/CO2020001471A2/es unknown
- 2020-02-13 CL CL2020000376A patent/CL2020000376A1/es unknown
- 2020-02-14 PH PH12020500341A patent/PH12020500341A1/en unknown
- 2020-02-14 ZA ZA2020/00970A patent/ZA202000970B/en unknown
-
2022
- 2022-01-10 CY CY20221100025T patent/CY1125355T1/el unknown
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