MA55503A - Amélioration de la chromatographie d'affinité d'immunoglobulines au moyen d'une floculation de pré-capture - Google Patents

Amélioration de la chromatographie d'affinité d'immunoglobulines au moyen d'une floculation de pré-capture

Info

Publication number
MA55503A
MA55503A MA055503A MA55503A MA55503A MA 55503 A MA55503 A MA 55503A MA 055503 A MA055503 A MA 055503A MA 55503 A MA55503 A MA 55503A MA 55503 A MA55503 A MA 55503A
Authority
MA
Morocco
Prior art keywords
flocculation
capture
improvement
affinity chromatography
immunoglobulin affinity
Prior art date
Application number
MA055503A
Other languages
English (en)
Inventor
Zsuzsanna Keszey
Zoltán Sütö
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of MA55503A publication Critical patent/MA55503A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/12—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Water Supply & Treatment (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
MA055503A 2019-04-04 2020-03-25 Amélioration de la chromatographie d'affinité d'immunoglobulines au moyen d'une floculation de pré-capture MA55503A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUP1900112A HU231498B1 (hu) 2019-04-04 2019-04-04 Immunglobulinok affinitás kromatográfiájának fejlesztése kötést megelőző flokkulálás alkalmazásával

Publications (1)

Publication Number Publication Date
MA55503A true MA55503A (fr) 2022-02-09

Family

ID=89992878

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055503A MA55503A (fr) 2019-04-04 2020-03-25 Amélioration de la chromatographie d'affinité d'immunoglobulines au moyen d'une floculation de pré-capture

Country Status (12)

Country Link
US (1) US20220194981A1 (fr)
EP (1) EP3947414A1 (fr)
JP (1) JP7333412B2 (fr)
KR (1) KR20210149089A (fr)
CN (1) CN113710685A (fr)
AU (1) AU2020252054A1 (fr)
BR (1) BR112021017206A2 (fr)
CA (1) CA3130629A1 (fr)
HU (1) HU231498B1 (fr)
MA (1) MA55503A (fr)
SA (1) SA521430291B1 (fr)
WO (1) WO2020200980A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11964998B2 (en) * 2017-08-30 2024-04-23 Fresenius Kabi Deutschland Gmbh Method for purifying anti-IL-6 receptor antibodies
TW202233644A (zh) * 2020-10-30 2022-09-01 美商建南德克公司 用於獲得水解酵素活性率降低的醫藥組成物之純化平台
CA3200462A1 (fr) * 2020-12-18 2022-06-23 Sebastian Damerow Procedes de purification de proteine repliee fusionnee avec un fc-peptide
WO2023167852A2 (fr) * 2022-03-02 2023-09-07 Regeneron Pharmaceuticals, Inc. Procédés de culture cellulaire pour la production d'anticorps
CN115430198A (zh) * 2022-09-21 2022-12-06 英脉生物医药(杭州)有限公司 一种蛋白纯化方法和蛋白纯化***

Family Cites Families (21)

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DK1097945T3 (da) 1991-03-18 2007-11-05 Univ New York Monoklonale og kimære antistoffer, der er specifikke for human tumornekrosefaktor
EP0940468A1 (fr) 1991-06-14 1999-09-08 Genentech, Inc. Domaine variable d'un anticorps humanisé
RO118524B1 (ro) 1992-11-13 2003-06-30 Idec Pharmaceuticals Corp San Metoda pentru tratarea unei tulburari legata de celulele b
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
ATE239041T1 (de) 1996-02-09 2003-05-15 Basf Ag Humane antikörper welche an humanen tnfalpha binden
EP1787999B1 (fr) 1997-04-07 2010-08-04 Genentech, Inc. Anti-VEGF anticorps
JP2001194306A (ja) 2000-01-06 2001-07-19 Advantest Corp 化学物質検出方法及び装置
SG10201603108QA (en) 2001-06-26 2016-05-30 Amgen Inc Antibodies To OPGL
BRPI0616242A2 (pt) 2005-09-15 2011-06-14 Wyeth Corp floculaÇço de proteÍna usando sais
WO2008127305A2 (fr) 2006-11-01 2008-10-23 Biogen Idec Ma Inc. Procédé d'isolement de biomacromolécules utilisant un faible ph et des cations divalents
BRPI0806367A2 (pt) 2007-01-22 2011-09-06 Genentech Inc métodos de purificação de anticorpos
EP2445925A1 (fr) 2009-06-25 2012-05-02 Bristol-Myers Squibb Company Purification de protéines par précipitation de l'acide caprylique (l'acide octanoïque)
US8691918B2 (en) 2010-05-17 2014-04-08 Emd Millipore Corporation Stimulus responsive polymers for the purification of biomolecules
AR089231A1 (es) 2011-12-15 2014-08-06 Amgen Inc Metodo de floculacion
EP2682168A1 (fr) 2012-07-02 2014-01-08 Millipore Corporation Dispositif de tirage et métier à filer
KR20150123796A (ko) 2013-02-28 2015-11-04 에이전시 포 사이언스, 테크놀로지 앤드 리서치 크로마틴 결핍 세포 배양 수확물로부터의 항체들의 크로마토그래프 정제
EP3004135A4 (fr) 2013-06-04 2016-11-23 Agency Science Tech & Res Procédé de purification de protéine
SG11201607098SA (en) 2014-02-27 2016-09-29 Agency Science Tech & Res Antibody purification process
WO2015135884A1 (fr) * 2014-03-10 2015-09-17 Richter Gedeon Nyrt. Purification d'immunoglobuline à l'aide d'étapes de pré-nettoyage
US20180105555A1 (en) 2015-03-20 2018-04-19 Bristol-Myers Squibb Company Use of dextran for protein purification
US10927145B2 (en) * 2016-06-15 2021-02-23 Agency For Science, Technology And Research Method of enhancing the performance of chromatography methods for purification of proteins

Also Published As

Publication number Publication date
AU2020252054A1 (en) 2021-09-16
SA521430291B1 (ar) 2024-03-03
KR20210149089A (ko) 2021-12-08
HU231498B1 (hu) 2024-05-28
US20220194981A1 (en) 2022-06-23
WO2020200980A1 (fr) 2020-10-08
EP3947414A1 (fr) 2022-02-09
BR112021017206A2 (pt) 2021-12-14
HUP1900112A1 (hu) 2020-10-28
JP2022526965A (ja) 2022-05-27
CN113710685A (zh) 2021-11-26
CA3130629A1 (fr) 2020-10-08
JP7333412B2 (ja) 2023-08-24

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