MA29067B1 - Protéines de fusion de RAGE et méthodes d'utilisation - Google Patents
Protéines de fusion de RAGE et méthodes d'utilisationInfo
- Publication number
- MA29067B1 MA29067B1 MA29650A MA29650A MA29067B1 MA 29067 B1 MA29067 B1 MA 29067B1 MA 29650 A MA29650 A MA 29650A MA 29650 A MA29650 A MA 29650A MA 29067 B1 MA29067 B1 MA 29067B1
- Authority
- MA
- Morocco
- Prior art keywords
- methods
- fusion proteins
- rage fusion
- rage
- proteins
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59855504P | 2004-08-03 | 2004-08-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA29067B1 true MA29067B1 (fr) | 2007-12-03 |
Family
ID=35149359
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA29650A MA29067B1 (fr) | 2004-08-03 | 2007-02-02 | Protéines de fusion de RAGE et méthodes d'utilisation |
Country Status (23)
Country | Link |
---|---|
US (5) | US7901688B2 (fr) |
EP (1) | EP1781700B1 (fr) |
JP (1) | JP5188804B2 (fr) |
KR (1) | KR101323411B1 (fr) |
CN (1) | CN1993378A (fr) |
AP (1) | AP2007003869A0 (fr) |
AU (1) | AU2005271452B2 (fr) |
BR (1) | BRPI0514052A (fr) |
CA (1) | CA2570324C (fr) |
CR (1) | CR20110556A (fr) |
EA (1) | EA012082B1 (fr) |
EC (1) | ECSP077221A (fr) |
ES (1) | ES2473587T3 (fr) |
GE (1) | GEP20105110B (fr) |
IL (1) | IL180554A (fr) |
MA (1) | MA29067B1 (fr) |
MX (1) | MX2007001559A (fr) |
NO (1) | NO20065949L (fr) |
NZ (1) | NZ552128A (fr) |
TN (1) | TNSN07037A1 (fr) |
UA (1) | UA93356C2 (fr) |
WO (1) | WO2006017647A1 (fr) |
ZA (2) | ZA200700643B (fr) |
Families Citing this family (53)
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US6465422B1 (en) * | 1998-04-17 | 2002-10-15 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting tumor invasion or spreading in a subject |
US6303321B1 (en) | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
US7304034B2 (en) | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
US7696169B2 (en) * | 2003-06-06 | 2010-04-13 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
EP1668035A2 (fr) * | 2003-09-11 | 2006-06-14 | Critical Therapeutics, Inc. | Anticorps monoclonaux diriges contre hmgb1 |
EA012082B1 (ru) * | 2004-08-03 | 2009-08-28 | Транстек Фарма, Инк. | Белки слияния на основе rage и способы их использования |
EA012586B1 (ru) * | 2004-08-03 | 2009-10-30 | Транстек Фарма, Инк. | Rage-слитые белки и способы их применения |
WO2006119510A2 (fr) * | 2005-05-04 | 2006-11-09 | Receptor Biologix, Inc. | Isoformes d'un recepteur pour produits de glycation avancee (rage) et methodes d'identification et d'utilisation de celles-ci |
WO2007076200A2 (fr) * | 2005-11-28 | 2007-07-05 | Medimmune, Inc. | Antagonistes de hmgb1 et/ou rage et leurs procedes d'utilisation |
US7957931B2 (en) * | 2005-12-23 | 2011-06-07 | Gcoder Systems Ab | Positioning pattern |
EP1989227A2 (fr) * | 2006-02-09 | 2008-11-12 | Transtech Pharma, Inc. | Protéines hybrides rage et leurs procédés d'utilisation |
US7981424B2 (en) * | 2006-05-05 | 2011-07-19 | Transtech Pharma, Inc. | RAGE fusion proteins, formulations, and methods of use thereof |
CA3001783C (fr) | 2007-01-30 | 2020-09-08 | Epivax, Inc. | Epitopes de lymphocytes t regulateurs, compositions et utilisations de ceux-ci |
WO2008100470A2 (fr) * | 2007-02-15 | 2008-08-21 | Transtech Pharma, Inc. | Protéines de fusion de l'immunoglobuline et procédés de fabrication |
WO2008153957A1 (fr) * | 2007-06-07 | 2008-12-18 | The Trustees Of Columbia University In The City Of New York | Utilisation d'antagonistes de rage pour le traitement de l'obésité et de maladies associées |
CA2690056C (fr) * | 2007-06-14 | 2017-08-29 | Galactica Pharmaceuticals, Inc. | Proteines de fusion de page |
WO2009054435A1 (fr) * | 2007-10-24 | 2009-04-30 | Otsuka Chemical Co., Ltd. | Polypeptide à fonction effectrice améliorée |
NL2001553C2 (nl) * | 2008-05-06 | 2009-05-07 | Transtech Pharma | Rage-fusie-eiwitten, preparaten en werkwijzen voor het gebruik ervan. |
NL2001552C2 (nl) * | 2008-05-06 | 2009-05-07 | Transtech Pharma | Rage-fusie-eiwitten, preparaten en werkwijzen voor het gebruik ervan. |
NL2001554C2 (nl) * | 2008-05-06 | 2009-05-07 | Transtech Pharma | Rage-fusie-eiwitten, preparaten en werkwijzen voor het gebruik ervan. |
NL2001556C2 (nl) * | 2008-05-06 | 2009-05-07 | Transtech Pharma | Rage-fusie-eiwitten, preparaten en werkwijzen voor het gebruik ervan. |
NL2001558C2 (nl) * | 2008-05-06 | 2009-05-07 | Transtech Pharma | Rage-fusie-eiwitten, preparaten en werkwijzen voor het gebruik ervan. |
NL2001557C2 (nl) * | 2008-05-06 | 2009-05-07 | Transtech Pharma | Rage-fusie-eiwitten, preparaten en werkwijzen voor het gebruik ervan. |
NL2001551C2 (nl) * | 2008-05-06 | 2009-05-07 | Transtech Pharma | Rage-fusie-eiwitten, preparaten en werkwijzen voor het gebruik ervan. |
NL2001555C2 (nl) * | 2008-05-06 | 2009-05-07 | Transtech Pharma | Rage-fusie-eiwitten, preparaten en werkwijzen voor het gebruik ervan. |
JP2011521009A (ja) | 2008-05-23 | 2011-07-21 | シワ コーポレイション | 再生を促進させる方法、組成物及び装置 |
EP2421892A1 (fr) | 2009-04-20 | 2012-02-29 | Pfizer Inc. | Contrôle de la glycosylation de protéines, compositions et méthodes associées |
WO2011100508A2 (fr) * | 2010-02-12 | 2011-08-18 | Arizona Board Of Regents For And On Behalf Of Arizona State University | Procédés et compositions liés à des fusions glycoprotéine-immunoglobuline |
WO2011102845A1 (fr) * | 2010-02-18 | 2011-08-25 | Transtech Pharma, Inc. | Compositions de protéines de fusion rage et méthodes d'utilisation |
EP3511017A1 (fr) | 2010-09-27 | 2019-07-17 | Siwa Corporation | Élimination sélective de cellules modifiées par l'âge pour le traitement de l'athérosclérose |
US8721571B2 (en) | 2010-11-22 | 2014-05-13 | Siwa Corporation | Selective removal of cells having accumulated agents |
JP2014528913A (ja) | 2011-06-28 | 2014-10-30 | インヒブルクス リミティド ライアビリティ カンパニー | Wapドメイン融合ポリペプチド及びその使用方法 |
CN103917563A (zh) | 2011-06-28 | 2014-07-09 | 英伊布里克斯有限责任公司 | 丝氨酸蛋白酶抑制蛋白融合多肽及其使用方法 |
US10400029B2 (en) | 2011-06-28 | 2019-09-03 | Inhibrx, Lp | Serpin fusion polypeptides and methods of use thereof |
EP2892919A1 (fr) * | 2012-09-07 | 2015-07-15 | Sanofi | Protéines de fusion pour traiter un syndrome métabolique |
WO2015023165A1 (fr) * | 2013-08-16 | 2015-02-19 | 가톨릭대학교 산학협력단 | Composite de régulation d'une inflammation et cellules souches mésenchymateuse stabilisées ayant une fonction optimisée de régulation de l'immunité par blocage de la molécule de signalisation stat3 |
RU2721568C2 (ru) * | 2014-09-19 | 2020-05-20 | Сива Корпорейшн | Анти-age антитела для лечения воспаления и аутоиммунных нарушений |
US10358502B2 (en) | 2014-12-18 | 2019-07-23 | Siwa Corporation | Product and method for treating sarcopenia |
US9993535B2 (en) | 2014-12-18 | 2018-06-12 | Siwa Corporation | Method and composition for treating sarcopenia |
EP4067386A1 (fr) | 2016-02-19 | 2022-10-05 | Siwa Corporation | Procédé et composition pour traiter le cancer, tuer des cellules du cancer métastatique et prévenir des métastases cancéreuses à l'aide d'anticorps pour produits finaux de glycosylation avancée (rage) |
WO2018191718A1 (fr) | 2017-04-13 | 2018-10-18 | Siwa Corporation | Anticorps monoclonal humanisé de produit final de glycation avancée |
EP3443007A1 (fr) | 2016-04-15 | 2019-02-20 | Siwa Corporation | Anticorps anti-age pour le traitement de troubles neurodégénératifs |
CN115304669A (zh) * | 2016-06-08 | 2022-11-08 | 上海交通大学医学院 | 增强激动型抗体活性的抗体重链恒定区序列 |
EP3475306A1 (fr) | 2016-06-23 | 2019-05-01 | Siwa Corporation | Vaccins pour l'utilisation dans le traitement de diverses maladies et troubles |
US10925937B1 (en) | 2017-01-06 | 2021-02-23 | Siwa Corporation | Vaccines for use in treating juvenile disorders associated with inflammation |
US10995151B1 (en) | 2017-01-06 | 2021-05-04 | Siwa Corporation | Methods and compositions for treating disease-related cachexia |
US10858449B1 (en) | 2017-01-06 | 2020-12-08 | Siwa Corporation | Methods and compositions for treating osteoarthritis |
US10961321B1 (en) | 2017-01-06 | 2021-03-30 | Siwa Corporation | Methods and compositions for treating pain associated with inflammation |
US10143187B2 (en) | 2017-02-17 | 2018-12-04 | Denali Therapeutics Inc. | Transferrin receptor transgenic models |
JP2020508053A (ja) * | 2017-02-17 | 2020-03-19 | デナリ セラピューティクス インコーポレイテッドDenali Therapeutics Inc. | 操作されたポリペプチド |
US10457717B2 (en) | 2017-02-17 | 2019-10-29 | Denali Therapeutics Inc. | Engineered polypeptides |
US11518801B1 (en) | 2017-12-22 | 2022-12-06 | Siwa Corporation | Methods and compositions for treating diabetes and diabetic complications |
WO2020056379A1 (fr) | 2018-09-14 | 2020-03-19 | BioAge Labs, Inc. | Protéines de fusion rage présentant une stabilité et une affinité de liaison aux ligands améliorées et leurs utilisations |
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2005
- 2005-08-03 EA EA200700404A patent/EA012082B1/ru not_active IP Right Cessation
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- 2005-08-03 EP EP05778764.0A patent/EP1781700B1/fr active Active
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- 2005-08-03 CN CNA2005800259477A patent/CN1993378A/zh active Pending
- 2005-08-03 CA CA2570324A patent/CA2570324C/fr not_active Expired - Fee Related
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- 2005-08-03 ES ES05778764.0T patent/ES2473587T3/es active Active
- 2005-08-03 AU AU2005271452A patent/AU2005271452B2/en not_active Ceased
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- 2007-01-23 ZA ZA200700643A patent/ZA200700643B/xx unknown
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