MA26957A1 - SPIRO-PYRIMIDINE-2,4,6-TRIONES INHIBITORS OF METALLOPROTEINASES. - Google Patents
SPIRO-PYRIMIDINE-2,4,6-TRIONES INHIBITORS OF METALLOPROTEINASES.Info
- Publication number
- MA26957A1 MA26957A1 MA27117A MA27117A MA26957A1 MA 26957 A1 MA26957 A1 MA 26957A1 MA 27117 A MA27117 A MA 27117A MA 27117 A MA27117 A MA 27117A MA 26957 A1 MA26957 A1 MA 26957A1
- Authority
- MA
- Morocco
- Prior art keywords
- triones
- spiro
- pyrimidine
- inhibitors
- metalloproteinases
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Abstract
DEPOSANT Société dite : PFIZER PRODUCTS INC. REVENDICATION DE PRIORITES US 26 Octobre 2000 60/243,389 Voir en annexe le titre de l'invention et le texte de l'abrégé "Spiro-pyrimidine-2,4,6-triones inhibitrices de métalloproteinases" La présente invention concerne des 5-spiro-pyrimidine-2,4,6-triones, servant d'inhibiteurs de métalloproteinases, répondant a la formule dans laquelle ledit noyau "A" est un noyau hétérocyclique penta à heptagonal tel que défini dans le présent mémoire, et des compositions pharmaceutiques et méthodes de traitement de l'inflammation, du cancer et d'autres affections.DEPOSITOR Company known as: PFIZER PRODUCTS INC. CLAIM OF PRIORITIES US October 26, 2000 60 / 243,389 See appendix the title of the invention and the text of the abstract "Spiro-pyrimidine-2,4,6-triones inhibitors of metalloproteinases" The present invention relates to 5-spiro -pyrimidine-2,4,6-triones, serving as metalloproteinase inhibitors, corresponding to the formula in which said nucleus "A" is a penta to heptagonal heterocyclic nucleus as defined herein, and pharmaceutical compositions and methods for treating inflammation, cancer and other conditions.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24338900P | 2000-10-26 | 2000-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA26957A1 true MA26957A1 (en) | 2004-12-20 |
Family
ID=22918584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA27117A MA26957A1 (en) | 2000-10-26 | 2003-04-22 | SPIRO-PYRIMIDINE-2,4,6-TRIONES INHIBITORS OF METALLOPROTEINASES. |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP1332146A2 (en) |
| JP (1) | JP2004518635A (en) |
| KR (1) | KR20040004412A (en) |
| CN (1) | CN1501937A (en) |
| AP (1) | AP2001002318A0 (en) |
| AR (1) | AR035069A1 (en) |
| AU (1) | AU2002210813A1 (en) |
| BG (1) | BG107653A (en) |
| BR (1) | BR0114913A (en) |
| CA (1) | CA2425283A1 (en) |
| CZ (1) | CZ20031083A3 (en) |
| EA (1) | EA005762B1 (en) |
| EC (1) | ECSP034567A (en) |
| EE (1) | EE200300196A (en) |
| GT (1) | GT200100213A (en) |
| HN (1) | HN2001000244A (en) |
| HR (1) | HRP20030332A2 (en) |
| HU (1) | HUP0301577A3 (en) |
| IL (1) | IL154948A0 (en) |
| IS (1) | IS6762A (en) |
| MA (1) | MA26957A1 (en) |
| MX (1) | MXPA03003735A (en) |
| NO (1) | NO20031853L (en) |
| OA (1) | OA12529A (en) |
| PA (1) | PA8531401A1 (en) |
| PE (1) | PE20020589A1 (en) |
| PL (1) | PL366201A1 (en) |
| SK (1) | SK4972003A3 (en) |
| SV (1) | SV2003000705A (en) |
| TN (1) | TNSN01149A1 (en) |
| WO (1) | WO2002034753A2 (en) |
| ZA (1) | ZA200302190B (en) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2433772C (en) | 2001-02-14 | 2008-10-07 | Warner-Lambert Company Llc | Pyrimidine matrix metalloproteinase inhibitors |
| DOP2002000333A (en) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | DERIVATIVES OF ISOFTALIC ACID AS INHIBITORS OF METALOPROTEINASES OF THE MATRIX |
| ATE280164T1 (en) | 2001-02-14 | 2004-11-15 | Warner Lambert Co | BENZOTHIADIAZINE AS MATRIX METALPROTEINASE INHIBITORS |
| PA8539501A1 (en) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | TRIAZOLO COMPOUNDS AS MMP INHIBITORS |
| DOP2002000332A (en) | 2001-02-14 | 2002-08-30 | Warner Lambert Co | MATRIX METALOPROTEINAS PYRIDINE INHIBITORS |
| US6924276B2 (en) | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
| BR0213233A (en) | 2001-10-12 | 2005-01-04 | Warner Lambert Co | Matrix metalloproteinase inhibitor alkynes |
| US6962922B2 (en) | 2001-10-12 | 2005-11-08 | Warner-Lambert Company Llc | Alkynylated quinazoline compounds |
| US6894057B2 (en) | 2002-03-08 | 2005-05-17 | Warner-Lambert Company | Oxo-azabicyclic compounds |
| AU2003228701A1 (en) * | 2002-04-25 | 2003-11-10 | Bristol-Myers Squibb Company | Spirobarbituric acid derivatives useful as inhibitors of matrix metalloproteases |
| ES2247527T3 (en) * | 2002-04-26 | 2006-03-01 | Pfizer Prod Inc | METALOPROTEINASE TRIARIL-OXI-ARIL-ESPIRO-PYRIMIDINE-2,4,6-TRIONA INHIBITORS. |
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| US3714093A (en) * | 1970-05-19 | 1973-01-30 | American Home Prod | Spiro [heterocycloalkyl-2'(1'h)-quinazoline]-4'(3'h)-ones |
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| PA8498701A1 (en) * | 1999-08-12 | 2002-08-26 | Pfizer Prod Inc | PYRIMIDINE-2,4,6-METALOPROTEINASE INHIBITING TRIONES |
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2001
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- 2001-10-23 MX MXPA03003735A patent/MXPA03003735A/en unknown
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- 2001-10-23 EP EP01978721A patent/EP1332146A2/en not_active Withdrawn
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- 2001-10-23 KR KR10-2003-7005753A patent/KR20040004412A/en not_active Application Discontinuation
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