LV10102B - New non-hygroscopic mono-ammonium salts - Google Patents

New non-hygroscopic mono-ammonium salts Download PDF

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Publication number
LV10102B
LV10102B LVP-92-10A LV920010A LV10102B LV 10102 B LV10102 B LV 10102B LV 920010 A LV920010 A LV 920010A LV 10102 B LV10102 B LV 10102B
Authority
LV
Latvia
Prior art keywords
salt
mono
general formula
hygroscopic
acid
Prior art date
Application number
LVP-92-10A
Other languages
English (en)
Latvian (lv)
Other versions
LV10102A (lv
Inventor
Fulgencio M Powell
Laszlo Litkei
Vilmos Galamb
Imre Gulyas
Janos Repasi
Agota Repasine Veres
Jozsef Vig
Istvanne Koczka
Edit Fehervari
Laszlone Roka
Laszlone Pethe
Jozsef Neu
Original Assignee
Alkaloida Vegyeszeti Gyar Rt A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkaloida Vegyeszeti Gyar Rt A filed Critical Alkaloida Vegyeszeti Gyar Rt A
Publication of LV10102A publication Critical patent/LV10102A/xx
Publication of LV10102B publication Critical patent/LV10102B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
LVP-92-10A 1988-12-20 1992-05-04 New non-hygroscopic mono-ammonium salts LV10102B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU886497A HU201577B (en) 1988-12-20 1988-12-20 Process for producing cyclosporin antibiotics

Publications (2)

Publication Number Publication Date
LV10102A LV10102A (lv) 1994-05-10
LV10102B true LV10102B (en) 1995-02-20

Family

ID=10971727

Family Applications (2)

Application Number Title Priority Date Filing Date
LVP-92-10A LV10102B (en) 1988-12-20 1992-05-04 New non-hygroscopic mono-ammonium salts
LVP-93-708A LV10500B (en) 1988-12-20 1993-06-28 Method for producing of complex antibiotic- cyclosporin and/or it's components and method for producing of tolypocladium varium culture

Family Applications After (1)

Application Number Title Priority Date Filing Date
LVP-93-708A LV10500B (en) 1988-12-20 1993-06-28 Method for producing of complex antibiotic- cyclosporin and/or it's components and method for producing of tolypocladium varium culture

Country Status (23)

Country Link
US (1) US5156960A (fi)
EP (1) EP0379708B1 (fi)
JP (1) JPH0763356B2 (fi)
AT (1) AT393135B (fi)
BG (1) BG60274B2 (fi)
CA (1) CA2006144C (fi)
CZ (1) CZ283557B6 (fi)
DD (1) DD290356A5 (fi)
DE (1) DE58908740D1 (fi)
DK (1) DK174719B1 (fi)
FI (1) FI92603C (fi)
FR (1) FR2640641B1 (fi)
GB (1) GB2227489B (fi)
HU (1) HU201577B (fi)
IT (1) IT1237799B (fi)
LV (2) LV10102B (fi)
NO (1) NO175873C (fi)
PL (1) PL162959B1 (fi)
RU (1) RU1836425C (fi)
SE (1) SE505442C2 (fi)
SK (1) SK279768B6 (fi)
UA (1) UA13320A (fi)
YU (1) YU47100B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013094A1 (fr) * 1991-01-25 1992-08-06 Fujisawa Pharmaceutical Co., Ltd. Procede pour produire de la cyclosporine a et/ou c
DE59106428D1 (de) * 1991-04-06 1995-10-12 Dresden Arzneimittel Verfahren zur fermentativen Herstellung und Isolierung von Cyclosporin A sowie neue Cyclosporin- bildende Stämme.
FI92334C (fi) * 1992-12-30 1994-10-25 Leiras Oy Menetelmä syklosporiinien tuottamiseksi ja menetelmässä käytettävä uusi Tolypocladium-kanta
SI9300303A (en) * 1993-06-08 1994-12-31 Krka Tovarna Zdravil Process for isolation of hypolipemic effective substance
KR100304324B1 (ko) * 1994-10-13 2001-11-22 김용규 사이클로스포린a의제조방법
KR100341355B1 (ko) * 1994-10-14 2002-10-25 주식회사종근당 사이클로스포린a의제조방법
KR0126610B1 (ko) * 1994-10-18 1997-12-29 김충환 고생산 세포융합변이균주에 의한 사이클로스포린 a의 제조방법
EP0725076B1 (en) * 1995-02-01 2001-06-06 National Research Development Corporation of India A process for the preparation of cyclosporin A from tolypocladium species
US5854276A (en) * 1995-06-29 1998-12-29 Fujisawa Pharmaceutical Co., Ltd. Substance WF16616, process for production thereof, and use thereof
DE19611094C2 (de) 1996-03-21 1999-06-17 Dresden Arzneimittel Verfahren zur Reinigung von Cyclosporin A und/oder verwandten Cyclosporinen aus einem Cyclosporin-haltigen Rohextrakt unter Anwendung chromatographischer Verfahren mit Kieselgel als Adsorbens
US5709797A (en) * 1996-06-05 1998-01-20 Poli Industria Chimica S.P.A. Method of isolating cyclosporins
US5747330A (en) * 1996-06-05 1998-05-05 Poli Industria Chimica Antibiotic producing microbe
PT1154759E (pt) 1998-12-30 2008-11-20 Dexcel Ltd Concentrado dispersível para administração de ciclosporina
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
CA2401700A1 (en) 2000-02-29 2001-09-07 Biocon India Limited Manufacture and purification of cyclosporin a
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
EP2151450A1 (de) 2008-07-29 2010-02-10 Sandoz AG Verfahren zur Aufarbeitung von mikrobiologisch hergestellten zyklischen Oligopeptiden
CN103635188B (zh) * 2011-04-28 2017-03-22 细胞基因公司 使用pde4抑制剂用于治疗和控制自身免疫性疾病和炎性疾病的方法和组合物
GB201319791D0 (en) * 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
CN117025407B (zh) * 2023-06-28 2024-06-18 中国人民解放军海军特色医学中心 一株弯颈霉属真菌及其在制备抗辐损伤药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
US4215199A (en) * 1978-06-05 1980-07-29 Sandoz Ltd. Antibiotic production
SE448386B (sv) * 1978-10-18 1987-02-16 Sandoz Ag Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem
US4764503A (en) * 1986-11-19 1988-08-16 Sandoz Ltd. Novel cyclosporins

Also Published As

Publication number Publication date
SE8904262L (sv) 1990-06-21
RU1836425C (ru) 1993-08-23
AT393135B (de) 1991-08-26
FI92603C (fi) 1994-12-12
FR2640641B1 (fr) 1991-05-10
CZ283557B6 (cs) 1998-05-13
DK174719B1 (da) 2003-10-06
JPH02231071A (ja) 1990-09-13
YU241589A (en) 1991-02-28
FR2640641A1 (fr) 1990-06-22
BG60274B1 (bg) 1994-03-31
NO895160D0 (no) 1989-12-20
PL162959B1 (en) 1994-01-31
UA13320A (uk) 1997-02-28
EP0379708A1 (de) 1990-08-01
LV10500A (lv) 1995-02-20
SK722589A3 (en) 1999-03-10
HU201577B (en) 1990-11-28
NO175873B (fi) 1994-09-12
BG60274B2 (en) 1994-03-31
CZ722589A3 (cs) 1998-01-14
FI896157A0 (fi) 1989-12-20
CA2006144C (en) 1995-02-21
SK279768B6 (sk) 1999-03-12
US5156960A (en) 1992-10-20
NO175873C (no) 1994-12-21
CA2006144A1 (en) 1990-06-20
SE505442C2 (sv) 1997-08-25
IT1237799B (it) 1993-08-31
GB2227489B (en) 1992-09-16
YU47100B (sh) 1994-12-28
ATA289189A (de) 1991-01-15
DK640989A (da) 1990-06-21
LV10102A (lv) 1994-05-10
GB8928715D0 (en) 1990-02-28
HUT52164A (en) 1990-06-28
IT8922765A0 (it) 1989-12-20
FI92603B (fi) 1994-08-31
DE58908740D1 (de) 1995-01-19
SE8904262D0 (sv) 1989-12-19
EP0379708B1 (de) 1994-12-07
DD290356A5 (de) 1991-05-29
DK640989D0 (da) 1989-12-18
JPH0763356B2 (ja) 1995-07-12
NO895160L (no) 1990-06-21
GB2227489A (en) 1990-08-01
LV10500B (en) 1995-08-20

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