|
US4117118A
(en)
|
1976-04-09 |
1978-09-26 |
Sandoz Ltd. |
Organic compounds
|
|
FI65914C
(fi)
|
1978-03-07 |
1984-08-10 |
Sandoz Ag |
Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
|
|
US4215199A
(en)
|
1978-06-05 |
1980-07-29 |
Sandoz Ltd. |
Antibiotic production
|
|
IE54936B1
(en)
|
1980-02-14 |
1990-03-28 |
Sandoz Ltd |
A method for the total synthesis of cyclosporins, novel cyclosporins and novel intermediates and methods for their production
|
|
US5639724A
(en)
|
1984-07-24 |
1997-06-17 |
Sandoz Ltd. |
Cyclosporin galenic forms
|
|
US4861580A
(en)
|
1985-10-15 |
1989-08-29 |
The Liposome Company, Inc. |
Composition using salt form of organic acid derivative of alpha-tocopheral
|
|
US5154930A
(en)
|
1987-03-05 |
1992-10-13 |
The Liposome Company, Inc. |
Pharmacological agent-lipid solution preparation
|
|
KR880012221A
(ko)
|
1987-04-13 |
1988-11-26 |
사노 가즈오 |
에스테르 또는 아미드를 활성성분으로 함유하는 약제 조성물
|
|
ATE95193T1
(de)
|
1987-06-17 |
1993-10-15 |
Sandoz Ag |
Cyclosporine und deren benutzung als arzneimittel.
|
|
US5756450A
(en)
|
1987-09-15 |
1998-05-26 |
Novartis Corporation |
Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
|
|
US4814168A
(en)
|
1988-03-04 |
1989-03-21 |
Noven Pharmaceuticals, Inc. |
Transdermal multipolymer drug delivery system
|
|
US4994267A
(en)
|
1988-03-04 |
1991-02-19 |
Noven Pharmaceuticals, Inc. |
Transdermal acrylic multipolymer drug delivery system
|
|
GB8809616D0
(en)
|
1988-04-22 |
1988-05-25 |
Cancer Res Campaign Tech |
Further improvements relating to drug delivery systems
|
|
US5342625A
(en)
|
1988-09-16 |
1994-08-30 |
Sandoz Ltd. |
Pharmaceutical compositions comprising cyclosporins
|
|
KR0148748B1
(ko)
|
1988-09-16 |
1998-08-17 |
장 크라메르, 한스 루돌프 하우스 |
사이클로스포린을 함유하는 약학조성물
|
|
SE8804164A0
(sv)
|
1988-11-17 |
1990-05-18 |
Per Prisell |
Farmaceutisk beredning
|
|
HU201577B
(en)
|
1988-12-20 |
1990-11-28 |
Gyogyszerkutato Intezet |
Process for producing cyclosporin antibiotics
|
|
EP0388152B1
(en)
|
1989-03-15 |
1994-10-12 |
Merck & Co. Inc. |
Process for producing an immunosuppressant agent (demethimmunomycin) using a mutant strain of a microorganism
|
|
US5272068A
(en)
|
1989-03-15 |
1993-12-21 |
Merck & Co., Inc. |
Process for producing immunosuppressant agent L-683942 by fermentation
|
|
US5227165A
(en)
|
1989-11-13 |
1993-07-13 |
Nova Pharmaceutical Corporation |
Liposphere delivery systems for local anesthetics
|
|
IE904098A1
(en)
|
1989-11-13 |
1991-05-22 |
Nova Pharm Corp |
Lipospheres for controlled delivery of substances
|
|
US5188837A
(en)
|
1989-11-13 |
1993-02-23 |
Nova Pharmaceutical Corporation |
Lipsopheres for controlled delivery of substances
|
|
US5178866A
(en)
|
1990-03-23 |
1993-01-12 |
Alza Corporation |
Dosage form for delivering drug to the intestine
|
|
EP0484281B2
(en)
|
1990-11-02 |
2000-11-22 |
Novartis AG |
Cyclosporins
|
|
HU208491B
(en)
|
1990-11-27 |
1993-11-29 |
Gyogyszerkutato Intezet |
Process for producing oral pharmaceutical composition containing cyclosporin
|
|
WO1992013094A1
(fr)
|
1991-01-25 |
1992-08-06 |
Fujisawa Pharmaceutical Co., Ltd. |
Procede pour produire de la cyclosporine a et/ou c
|
|
US5378475A
(en)
|
1991-02-21 |
1995-01-03 |
University Of Kentucky Research Foundation |
Sustained release drug delivery devices
|
|
US5683714A
(en)
|
1991-04-19 |
1997-11-04 |
Nexstar Pharmaceuticals, Inc. |
Liposomal cyclosporin pharmaceutical formulation
|
|
DE69211691T2
(de)
|
1991-04-19 |
1997-01-16 |
Nexstar Pharmaceuticals Inc |
Pharmazeutische formulierung und pharmazeutisches verfahren
|
|
IL101007A
(en)
|
1992-02-18 |
1997-08-14 |
Pharmos Ltd |
Dry stable compositions prepared by lyophilization
|
|
US5637317A
(en)
|
1992-05-18 |
1997-06-10 |
Dietl; Hans |
Pharmaceutical preparation containing cyclosporin(s) for oral administration and process for producing same
|
|
US5529785A
(en)
|
1993-05-12 |
1996-06-25 |
Dietl; Hans |
Pharmaceutical preparation containing cyclosporin(s) for oral administration and process for producing same
|
|
HU213553B
(en)
|
1992-05-25 |
1997-07-28 |
Biogal Gyogyszergyar |
Process for isolating of cyclosporin-a
|
|
US5759566A
(en)
|
1992-07-28 |
1998-06-02 |
Poli Industria Chimica Spa |
Microemulsion pharmaceutical compositions for the delivery of pharmaceutically active agents
|
|
CZ278863B6
(en)
|
1992-09-07 |
1994-07-13 |
Galena |
Medicinal preparations with n-methylated cyclic undecapeptides
|
|
FI92334C
(fi)
|
1992-12-30 |
1994-10-25 |
Leiras Oy |
Menetelmä syklosporiinien tuottamiseksi ja menetelmässä käytettävä uusi Tolypocladium-kanta
|
|
JP3489831B2
(ja)
|
1993-04-20 |
2004-01-26 |
ヘクサル・アクチエンゲゼルシャフト |
活性成分パッチ
|
|
US5576016A
(en)
|
1993-05-18 |
1996-11-19 |
Pharmos Corporation |
Solid fat nanoemulsions as drug delivery vehicles
|
|
CH686761A5
(de)
|
1993-05-27 |
1996-06-28 |
Sandoz Ag |
Galenische Formulierungen.
|
|
US5639474A
(en)
|
1993-07-01 |
1997-06-17 |
Hanmi Pharm. Ind., Ltd. |
Cyclosporin soft capsule composition
|
|
SI0649651T1
(en)
|
1993-09-28 |
2001-02-28 |
Scherer Gmbh R P |
Soft gelatin capsule manufacture
|
|
DE4340781C3
(de)
|
1993-11-30 |
2000-01-27 |
Novartis Ag |
Cyclosporin enthaltende flüssige Zubereitungen und Verfahren zu ihrer Herstellung
|
|
PL178397B1
(pl)
*
|
1994-02-04 |
2000-04-28 |
Scotia Lipidteknik Ab |
Emulsja typu olej w wodzie i środek farmaceutyczny zawierający emulsję typu olej w wodzie
|
|
US5891846A
(en)
|
1994-02-17 |
1999-04-06 |
Shiseido Company, Ltd. |
Cyclosporin-containing emulsion composition
|
|
KR0146671B1
(ko)
|
1994-02-25 |
1998-08-17 |
김충환 |
사이클로스포린-함유 분말 조성물
|
|
GB9405304D0
(en)
|
1994-03-16 |
1994-04-27 |
Scherer Ltd R P |
Delivery systems for hydrophobic drugs
|
|
US5430021A
(en)
|
1994-03-18 |
1995-07-04 |
Pharmavene, Inc. |
Hydrophobic drug delivery systems
|
|
US5651980A
(en)
|
1994-04-15 |
1997-07-29 |
Biohybrid Technologies, Inc. |
Methods of use of uncoated gel particles
|
|
WO1995032726A1
(en)
|
1994-06-01 |
1995-12-07 |
Yuhan Corporation |
Cyclosporin containing composition and process for the preparation thereof
|
|
US5958458A
(en)
|
1994-06-15 |
1999-09-28 |
Dumex-Alpharma A/S |
Pharmaceutical multiple unit particulate formulation in the form of coated cores
|
|
KR100304324B1
(ko)
|
1994-10-13 |
2001-11-22 |
김용규 |
사이클로스포린a의제조방법
|
|
KR0126610B1
(ko)
|
1994-10-18 |
1997-12-29 |
김충환 |
고생산 세포융합변이균주에 의한 사이클로스포린 a의 제조방법
|
|
US5603951A
(en)
|
1994-11-09 |
1997-02-18 |
Hanmi Pharm. Ind. Co., Ltd. |
Cyclosporin-containing soft capsule compositions
|
|
DE4440337A1
(de)
|
1994-11-11 |
1996-05-15 |
Dds Drug Delivery Services Ges |
Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
|
|
HU215966B
(hu)
|
1994-11-21 |
1999-07-28 |
BIOGAL Gyógyszergyár Rt. |
Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
|
|
KR0167613B1
(ko)
|
1994-12-28 |
1999-01-15 |
한스 루돌프 하우스, 니콜 케르커 |
사이클로스포린-함유 연질캅셀제 조성물
|
|
EP0725076B1
(en)
|
1995-02-01 |
2001-06-06 |
National Research Development Corporation of India |
A process for the preparation of cyclosporin A from tolypocladium species
|
|
US5573783A
(en)
|
1995-02-13 |
1996-11-12 |
Nano Systems L.L.C. |
Redispersible nanoparticulate film matrices with protective overcoats
|
|
FI102758B
(fi)
|
1995-03-03 |
1999-02-15 |
Santen Pharmaceutical Co Ltd |
Menetelmä puhtaan syklosporiinimuodon valmistamiseksi
|
|
IE75744B1
(en)
|
1995-04-03 |
1997-09-24 |
Elan Corp Plc |
Controlled release biodegradable micro- and nanospheres containing cyclosporin
|
|
WO1996033697A1
(fr)
|
1995-04-24 |
1996-10-31 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Formulation auto-emulsionnable formant une emulsion huile dans l'eau
|
|
US5716928A
(en)
|
1995-06-07 |
1998-02-10 |
Avmax, Inc. |
Use of essential oils to increase bioavailability of oral pharmaceutical compounds
|
|
US5616595A
(en)
|
1995-06-07 |
1997-04-01 |
Abbott Laboratories |
Process for recovering water insoluble compounds from a fermentation broth
|
|
US5665386A
(en)
|
1995-06-07 |
1997-09-09 |
Avmax, Inc. |
Use of essential oils to increase bioavailability of oral pharmaceutical compounds
|
|
US5656287A
(en)
|
1995-06-07 |
1997-08-12 |
Nexstar Pharmaceuticals, Inc. |
Liposomal cyclosporin formulations as agents for immunosuppression and multiple drug resistant indications
|
|
US5827822A
(en)
|
1996-03-25 |
1998-10-27 |
Sangstat Medical Corporation |
Cyclosporin a formulations as nanoparticles
|
|
US5962019A
(en)
|
1995-08-25 |
1999-10-05 |
Sangstat Medical Corporation |
Oral cyclosporin formulations
|
|
EP0760237A1
(en)
|
1995-08-30 |
1997-03-05 |
Cipla Limited |
Oil-in-water microemulsions
|
|
US5968972A
(en)
|
1995-10-26 |
1999-10-19 |
Baker Norton Pharmaceuticals, Inc. |
Method for increasing the oral bioactivity of pharmaceutical agents
|
|
NZ280689A
(en)
|
1995-12-15 |
1997-08-22 |
Bernard Charles Sherma Sherman |
Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol
|
|
KR970064620A
(ko)
*
|
1996-03-05 |
1997-10-13 |
임성기 |
사이클로스포린-함유 외용약제 조성물
|
|
DE19611094C2
(de)
|
1996-03-21 |
1999-06-17 |
Dresden Arzneimittel |
Verfahren zur Reinigung von Cyclosporin A und/oder verwandten Cyclosporinen aus einem Cyclosporin-haltigen Rohextrakt unter Anwendung chromatographischer Verfahren mit Kieselgel als Adsorbens
|
|
IL117773A
(en)
|
1996-04-02 |
2000-10-31 |
Pharmos Ltd |
Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability
|
|
US5660858A
(en)
|
1996-04-03 |
1997-08-26 |
Research Triangle Pharmaceuticals |
Cyclosporin emulsions
|
|
US5747330A
(en)
|
1996-06-05 |
1998-05-05 |
Poli Industria Chimica |
Antibiotic producing microbe
|
|
US5709797A
(en)
|
1996-06-05 |
1998-01-20 |
Poli Industria Chimica S.P.A. |
Method of isolating cyclosporins
|
|
US5958876A
(en)
|
1996-06-19 |
1999-09-28 |
Novartis Ag |
Cyclosporin-containing pharmaceutical compositions
|
|
US5958378A
(en)
|
1996-07-03 |
1999-09-28 |
Research Development Foundation |
High dose liposomal aerosol formulations containing cyclosporin A or budesonide
|
|
KR980008239A
(ko)
|
1996-07-26 |
1998-04-30 |
김충환 |
사이클로스포린-함유 약학적 조성물
|
|
US5798333A
(en)
|
1996-09-17 |
1998-08-25 |
Sherman; Bernard C. |
Water-soluble concentrates containing cyclosporins
|
|
CA2284000C
(en)
|
1997-03-12 |
2012-01-03 |
Abbott Laboratories |
Hydrophilic binary systems for the administration of cyclosporine
|
|
US5891845A
(en)
|
1997-11-21 |
1999-04-06 |
Fuisz Technologies Ltd. |
Drug delivery systems utilizing liquid crystal structures
|
|
US6028067A
(en)
*
|
1997-12-05 |
2000-02-22 |
Chong Kun Dang Corp. |
Cyclosporin-containing microemulsion preconcentrate composition
|
|
ID25908A
(id)
*
|
1998-03-06 |
2000-11-09 |
Novartis Ag |
Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
|
|
FR2780061B1
(fr)
|
1998-06-22 |
2001-09-07 |
Rhone Poulenc Rorer Sa |
Nouveau procede de preparation de derives de cyclosporine
|
|
US6267985B1
(en)
|
1999-06-30 |
2001-07-31 |
Lipocine Inc. |
Clear oil-containing pharmaceutical compositions
|
|
US6057289A
(en)
|
1999-04-30 |
2000-05-02 |
Pharmasolutions, Inc. |
Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system
|
|
HUP0400263A2
(hu)
*
|
2001-06-21 |
2005-03-29 |
Pfizer Products Inc. |
Koleszteril-észter transzfer protein inhibitort tartalmazó önemulgeáló készítmény
|