LU88750I2 - VENLAFAXINE et ses dérivés pharmaceutiquement acceptables - Google Patents

VENLAFAXINE et ses dérivés pharmaceutiquement acceptables

Info

Publication number
LU88750I2
LU88750I2 LU88750C LU88750C LU88750I2 LU 88750 I2 LU88750 I2 LU 88750I2 LU 88750 C LU88750 C LU 88750C LU 88750 C LU88750 C LU 88750C LU 88750 I2 LU88750 I2 LU 88750I2
Authority
LU
Luxembourg
Prior art keywords
venlafaxine
pharmaceutically acceptable
acceptable derivatives
derivatives
pharmaceutically
Prior art date
Application number
LU88750C
Other languages
English (en)
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838316646A external-priority patent/GB8316646D0/en
Priority claimed from US06/545,701 external-priority patent/US4535186A/en
Application filed by American Home Prod filed Critical American Home Prod
Publication of LU88750I2 publication Critical patent/LU88750I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/68—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/70—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/36—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/37—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by etherified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
LU88750C 1982-12-13 1983-12-07 VENLAFAXINE et ses dérivés pharmaceutiquement acceptables LU88750I2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US44903282A 1982-12-13 1982-12-13
US48659483A 1983-04-19 1983-04-19
GB838316646A GB8316646D0 (en) 1983-06-18 1983-06-18 Phenethylamine derivatives
US06/545,701 US4535186A (en) 1983-04-19 1983-10-26 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives

Publications (1)

Publication Number Publication Date
LU88750I2 true LU88750I2 (fr) 1996-08-23

Family

ID=27449489

Family Applications (1)

Application Number Title Priority Date Filing Date
LU88750C LU88750I2 (fr) 1982-12-13 1983-12-07 VENLAFAXINE et ses dérivés pharmaceutiquement acceptables

Country Status (7)

Country Link
EP (1) EP0112669B1 (fr)
AU (1) AU567524B2 (fr)
DE (2) DE19675025I2 (fr)
GB (2) GB2133788B (fr)
IE (1) IE56324B1 (fr)
LU (1) LU88750I2 (fr)
NL (1) NL940020I2 (fr)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU566673B2 (en) * 1983-09-15 1987-10-29 F. Hoffmann-La Roche Ag Phenethylamine derivatives
GB8501192D0 (en) * 1985-01-17 1985-02-20 Boots Co Plc Therapeutic agents
US4609758A (en) 1985-05-09 1986-09-02 American Home Products Corporation Phenoxyethylamine derivatives
GB8902209D0 (en) * 1989-02-01 1989-03-22 Wyeth John And Brother Limited Preparation of cyclohexanol derivatives and novel thioamide intermediates
US6440457B1 (en) 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
PT1153603E (pt) * 1993-06-28 2007-01-31 Wyeth Corp Novos tratamentos utilizando derivados de fenetilamina
TW344661B (en) * 1993-11-24 1998-11-11 Lilly Co Eli Pharmaceutical composition for treatment of incontinence
EP1331003B1 (fr) * 1996-03-25 2015-08-26 Wyeth LLC Composition de venlafaxine à libération prolongée
PE57198A1 (es) * 1996-03-25 1998-10-10 American Home Prod Formula de liberacion prolongada
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
DK1466889T3 (da) * 1999-04-06 2008-09-08 Sepracor Inc O-Desmethylvenlafaxin-succinat
TWI228118B (en) * 2000-08-30 2005-02-21 Ciba Sc Holding Ag Process for the preparation of substituted phenylacetonitriles
JP4180368B2 (ja) * 2000-10-31 2008-11-12 サンド・アクチエンゲゼルシヤフト 塩酸ベンラファキシンの結晶形
WO2002046140A1 (fr) * 2000-12-07 2002-06-13 Dr. Reddy's Laboratories Ltd. Nouvelles formes polymorphes cristallines d'hydrochlorure de venlafaxine et procede permettant leur fabrication
ATE369330T1 (de) 2001-02-12 2007-08-15 Wyeth Corp O-desmethyl-venlafaxine succinat salz
US6350912B1 (en) 2001-02-28 2002-02-26 Council Of Scientific And Industrial Research One pot process for the preparation of 1-[2-dimethylamino-(4-methoxyphenyl)-ethyl]cyclohexanol
ATE297373T1 (de) * 2001-02-28 2005-06-15 Council Scient Ind Res Verfahren zur herstellung von 1-(2-dimethylamino- (4-methoxyphenyl)-ethyl)cyclohexanol
DE60136263D1 (de) 2001-04-10 2008-12-04 Alembic Ltd Zwischenprodukt zur Herstellung von 1-Ä2-Dimethylamino-1-(4-methoxyphenyl)-ethylÜ-cyclohexanol
GB0126036D0 (en) * 2001-10-30 2001-12-19 Amedis Pharm Ltd Silicon compounds
DE10161818A1 (de) 2001-12-14 2003-06-26 Gruenenthal Gmbh Substituierte 1,5-Diaminopentan-3-ol-Verbindungen
JP4445853B2 (ja) 2002-06-10 2010-04-07 ワイス エルエルシー 新規ｏ−デスメチルベンラファクシンギ酸塩
WO2004094436A1 (fr) * 2003-04-24 2004-11-04 Amedis Pharmaceuticals Ltd. Derives de 1-(2-amino-1-phenyl-ethyl)-silacyclohexan-1-ol et utilisation desdits derives pour preparer un medicament
WO2005049560A2 (fr) * 2003-09-29 2005-06-02 Sun Pharmaceutical Industries Limited Procede de preparation d'un compose antidepresseur
PE20050954A1 (es) * 2003-10-02 2005-12-20 Wyeth Corp Proceso para la preparacion de compuestos de 1-[ciano(fenil)metil]-ciclohexanol
DE10359154A1 (de) 2003-12-16 2005-07-28 Krka Tovarna Zdravil, D.D. Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I
EP1902015A1 (fr) * 2005-06-29 2008-03-26 Wyeth Procede de preparation de composes de 1-[cyano (4-hydroxyphenyl)methyl]cyclohexanol
EP1954669B1 (fr) 2005-12-01 2015-07-08 Auspex Pharmaceuticals, Inc. Phénétylamines substituées à l activité sérotoninergique et/ou norépinephrinergique
CN101336226B (zh) * 2005-12-01 2012-05-23 奥斯拜客斯制药有限公司 具有5-羟色胺能活性和/或去甲肾上腺素能活性的取代的苯乙胺
EP1973866A1 (fr) 2005-12-20 2008-10-01 Synthon B.V. Procede de fabrication de la desvenlafaxine
WO2007094008A2 (fr) * 2006-02-16 2007-08-23 Unichem Laboratories Limited Nouveau procédé pour la préparation de chlorhydrate de venlafaxine et de ses intermédiaires
MX2007016179A (es) 2006-04-17 2008-03-11 Teva Pharma Formas cristalinas de o-desmetilvenlafaxina.
JP4763788B2 (ja) * 2006-07-26 2011-08-31 テバ ファーマシューティカル インダストリーズ リミティド Ｏ−デスメチルベンラファキシンの合成方法
KR101019454B1 (ko) 2006-07-26 2011-03-07 테바 파마슈티컬 인더스트리즈 리미티드 Ｏ-데스메틸벤라팍신의 합성 방법
FR2909089B1 (fr) 2006-11-23 2009-02-27 Ppg Sipsy Soc Par Actions Simp Procede in situ ou "one pot" d'hydrogenation et d'amination reductrice
WO2008090465A2 (fr) * 2007-01-22 2008-07-31 Medichem, S.A. Procédé amélioré de synthèse d'une base libre de la desvenlafaxine et de sels ou de solvates de celle-ci
AU2008211711A1 (en) * 2007-01-31 2008-08-07 Generics [Uk] Limited Process for the preparation of O-desmethyl venlafaxine
AR065728A1 (es) 2007-03-15 2009-06-24 Auspex Pharmaceuticals Inc Fenetilaminas sustituidas con actividad de serotoninergico y/o norepinefrinergico
WO2009017813A1 (fr) * 2007-08-02 2009-02-05 Teva Pharmaceutical Industries Ltd. Saccharinate d'o-desméthyl-venlafaxine
US20110046231A1 (en) * 2007-10-22 2011-02-24 Actavis Group Ptc Ehf Solid forms of (±)-o-desmethylvenlafaxine salts
WO2009070311A2 (fr) 2007-11-26 2009-06-04 Teva Pharmaceutical Industries Ltd. Formes cristallines de fumarate de o-desméthylvenlafaxine
EP2085377A1 (fr) 2008-01-29 2009-08-05 LEK Pharmaceuticals D.D. Nouveaux sels d'O-desméthyl-venlafaxine
EP2252573A2 (fr) * 2008-02-14 2010-11-24 Egis Gyógyszergyár Nyilvánosan Müködö Nouvelles formes polymorphes et amorphes du fumarate de desvenlafaxine
US8461389B2 (en) 2008-04-18 2013-06-11 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals
EP2119696A1 (fr) 2008-05-16 2009-11-18 Krka Préparation de sels de O-desméthylvenlafaxine
EP2119695A1 (fr) 2008-05-16 2009-11-18 Krka Préparation de sels de O-desméthylvenlafaxine
CZ2008756A3 (cs) * 2008-11-27 2010-03-24 Zentiva, A. S. Zpusob prípravy desvenlafaxinu a jeho solí
CZ2009454A3 (cs) * 2009-07-15 2010-11-10 Zentiva, K. S. Zpusob prípravy desvenlafaxinu a jeho solí
AU2009356897A1 (en) 2009-12-16 2012-08-09 Pharmathen S.A. Process for the preparation of O-desmethyl-venlafaxine and salts thereof
US8569371B2 (en) 2010-03-29 2013-10-29 Pliva Hrvatska D.O.O. Crystal forms of O-desmethylvenlafaxine fumarate
EP2746264A1 (fr) 2012-12-19 2014-06-25 Basf Se [1,2,4]triazole substitué et composés d'imidazole
EP2746255A1 (fr) 2012-12-19 2014-06-25 Basf Se Composés de [1,2,4]triazole et d'imidazole substitués
IN2013DE03197A (fr) 2013-10-29 2015-05-01 Council Scient Ind Res
CN104529797A (zh) * 2014-12-05 2015-04-22 南昌市博泽康医药科技有限公司 盐酸文拉法辛手性晶型的制备

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1124485B (de) * 1960-02-12 1962-03-01 Hoechst Ag Verfahren zur Herstellung von analeptisch wirksamen Phenylcycloalkylmethylaminen
GB1098835A (en) * 1965-07-13 1968-01-10 Jacques Logeais Sa Lab Spiro-oxazolidinones, spiro-oxazines, their process of preparation and therapeutic compositions containing said derivatives
JPS56113748A (en) * 1980-02-13 1981-09-07 Kowa Co Aminoethanol derivative and its preparation

Also Published As

Publication number Publication date
GB8332598D0 (en) 1984-01-11
GB8603901D0 (en) 1986-03-26
IE832818L (en) 1984-06-13
DE19675025I2 (de) 2003-05-22
EP0112669B1 (fr) 1987-07-29
GB2173787B (en) 1987-07-15
AU2212383A (en) 1984-06-21
IE56324B1 (en) 1991-06-19
AU567524B2 (en) 1987-11-26
NL940020I2 (nl) 1999-07-01
EP0112669A3 (en) 1984-11-28
EP0112669A2 (fr) 1984-07-04
DE3372753D1 (en) 1987-09-03
GB2133788A (en) 1984-08-01
GB2173787A (en) 1986-10-22
NL940020I1 (nl) 1994-12-16
GB2133788B (en) 1987-07-15

Similar Documents

Publication Publication Date Title
LU88750I2 (fr) VENLAFAXINE et ses dérivés pharmaceutiquement acceptables
LU88736I2 (fr) Cefquinome et ses dérivés pharmaceutiquement acceptables (COBACTAN)
LU90951I2 (fr) Eurifel rcp felv et ses dérivés pharmaceutiquement acceptables
LU90037I2 (fr) Konakion et ses dérivés pharmaceutiquement acceptables
LU90829I2 (fr) Tepoxalin-zubrin et ses d-riv-s pharmaceutiquement acceptables
LU91205I2 (fr) Ciclesonide et ses dérivés pharmaceutiquement acceptables (alvesco)
LU90069I2 (fr) Lercanidipine et ses sels et dérivés pharmaceutiquement acceptables (Zanidip)
DK32982A (da) Terapeutisk nyttige tetralinderivater
LU90736I2 (fr) Agenerase-amprenavir et ses d-riv-s pharmaceutiquement acceptables
BR1100036A (pt) Composto e composição farmacêutica
LU91072I2 (fr) Eplerenone et ses sels pharmaceutiquement acceptables - INSPRA
FI833728A0 (fi) Oral doseringsform
DE3368057D1 (en) Pharmaceutically active aminobenzopyrans
DE3275540D1 (en) Pharmaceutically active (3-aminopropoxy)-bibenzyl derivatives
LU88790I2 (fr) Moxidectin et ses dérivés pharmaceutiquement acceptables
LU88843I2 (fr) Ropivacaine et ses dérivés pharmaceutiquement acceptables (Naropine R)
DE3371906D1 (de) Deazapurine derivatives
BR8502442A (pt) Metodos e composicoes para a deteccao da doenca do legionario
IT1148169B (it) Composti carcinostatici e procedimento per la loro sintesi
FI831687L (fi) Farmaceutiska blandningar vilka innehaoller flere aktiva bestaondsdelar
LU90110I2 (fr) Penciclovir et ses dérivés pharmaceutiquement acceptables
FI834429A0 (fi) Framstaellning och terapeutisk tillaempning av 3',5'-diarabinosider
ZA794581B (en) N 2-arylsulfonyl-l-argininamides and the pharmaceutically acceptable salts thereof
LU88603I2 (fr) Trimetrexate glucuronate et ses dérivés pharmaceutiquement acceptables (NEUTREXIN R)
DK224583A (da) Herbicidt aktive phenoxybenzoyliminderivater