KR950007868A - 항궤양제 및 헬리코박터·피롤리의 정착저해제 - Google Patents

항궤양제 및 헬리코박터·피롤리의 정착저해제 Download PDF

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KR950007868A
KR950007868A KR1019940024098A KR19940024098A KR950007868A KR 950007868 A KR950007868 A KR 950007868A KR 1019940024098 A KR1019940024098 A KR 1019940024098A KR 19940024098 A KR19940024098 A KR 19940024098A KR 950007868 A KR950007868 A KR 950007868A
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fucoidan
active ingredient
fixation
pyrroli
algae extract
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KR1019940024098A
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KR100296089B1 (ko
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이쭈코. 키무라
히데유키 시바타
마사토 나가오카
슈우수케 하시모토
하루지 사와다
테루오 요코쿠라
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쿠와하라 쥰
카부시키가이샤 야쿠루트혼샤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/04—Rhodophycota or rhodophyta (red algae), e.g. Porphyra
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/11—Preparation or pretreatment of starting material involving culturing conditions, e.g. cultivation in the dark or under defined water stress
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

위점막에 있어서 궤양의 치료 및 예방과, 위점막에 대한 헬리코박터·피롤리의 정착을 저해하는 것에 유효하고, 안전성이 우수한 신규한 약제를 제공한다. 홍조류 또는 갈조류의 추출물중에 함유되어 있는 다당류 즉, 푸코이단을 유효성분으로 하는 항궤양제 및 헬리코박터·피롤리의 정착저해제.

Description

항궤양제 및 헬리코박터·피롤리의 정착저해제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (14)

  1. 푸코이단을 유효성분으로 하는 항궤양제.
  2. 푸코이단을 함유하는 홍조류추출물 또는 갈조류추출물을 유효성분으로 하는 항궤양제.
  3. 푸코이단을 함유하는 파에오파이세아 코다리아레스·네마시스투스(Phaeophyceae Chordariales nemacystus)추출물을 유효성분으로 하는 항궤양제.
  4. 제1항 내지 제3항중 어느 한항에 있어서, 상기 푸코이단이 저분화처리된 항궤양제.
  5. 푸코이단을 유효성분으로 하는 헬로코박터·피롤리의 정착저해제.
  6. 푸코이단을 함유하는 홍조류추출물 또는 갈조류추출물을 유효성분으로 하는 헬로코박터·피롤리의 정착저해제.
  7. 푸코이단을 함유하는 파에오파이세아 코다리아레스·네마시스투스추출을 유효성분으로 하는 헬리코박터·피롤리의 정착저해제.
  8. 저분자화처리된 푸코이단을 유효성분으로 하는 헬리코박터·피롤리의 정착저해제.
  9. 저분자화처리된 푸코이단을 함유하는 홍조류추출물 또는 갈조류추출물을 유효성분으로 하는 헬리코박터·피롤리의 정착저해제.
  10. 저분자화처리된 푸코이단을 함유하는 파에오파이세아 코다리아레스·네마시스투스추출을 유효성분으로 하는 헬리코박터·피롤리의 정착저해제.
  11. 치료유효량의 푸코이단을 유효성분으로 하는 항궤양 조성물.
  12. 치료유효량의 푸코이단을 유효성분으로 하는 헬리코박터·피롤리의 정착저해 조성물.
  13. 위점막상의 궤양 및 종양을 예방하고 치료하는 약제의 제조용으로서 제1항의 항궤양제의 용도.
  14. 위점막상에 헬리코박터·피롤리의 정착을 저해하는 약제의 제조용으로서 제5항의 정착저해제의 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940024098A 1993-09-24 1994-09-24 항궤양제및헬리코박터.파일로리의정착저해제 KR100296089B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP25888393 1993-09-24
JP93-258883 1993-09-24
JP94-111946 1994-04-28
JP11194694A JP3403496B2 (ja) 1993-09-24 1994-04-28 抗潰瘍剤およびヘリコバクター・ピロリの定着阻害剤

Publications (2)

Publication Number Publication Date
KR950007868A true KR950007868A (ko) 1995-04-15
KR100296089B1 KR100296089B1 (ko) 2001-10-24

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Country Status (10)

Country Link
EP (1) EP0645143B1 (ko)
JP (1) JP3403496B2 (ko)
KR (1) KR100296089B1 (ko)
CN (1) CN1096867C (ko)
AT (1) ATE193449T1 (ko)
AU (1) AU7418794A (ko)
CA (1) CA2132150C (ko)
DE (1) DE69424731T2 (ko)
NZ (1) NZ264517A (ko)
TW (1) TW438593B (ko)

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JP3916394B2 (ja) * 1996-01-26 2007-05-16 タカラバイオ株式会社 フコース硫酸含有多糖
CA2243543A1 (en) * 1996-01-26 1997-07-31 Research Institute For Glycotechnology Apoptosis inducers
US6573250B2 (en) 1996-06-12 2003-06-03 Takara Shuzo Co., Ltd. Food or beverage additive containing fucoidan and food and beverage containing fucoidan
CA2253573C (en) * 1996-06-12 2005-12-06 Takara Shuzo Co., Ltd. Fucoidan-containing foods or beverages
DE69718645T2 (de) * 1996-07-01 2003-08-21 Otsuka Pharma Co Ltd Verwendung des heisswasser-extrakts von ''nemacystus decipiens''
JPH1070970A (ja) * 1996-07-01 1998-03-17 Nisshinbo Ind Inc モズク熱水抽出物及びその用途
JPH10191940A (ja) * 1997-01-16 1998-07-28 Yakult Honsha Co Ltd モズク抽出物の品質改良法およびモズク抽出物
JPH1135591A (ja) * 1997-07-18 1999-02-09 Masakuni Tako オキナワモズクから分離したフコイダンからのｌ−フコ ースの製造とそれの製造法
JPH1160590A (ja) 1997-08-22 1999-03-02 Yakult Honsha Co Ltd オリゴフコース誘導体又はオリゴラムノース誘導体及びその製造法
JPH11228602A (ja) * 1998-02-09 1999-08-24 Yakult Honsha Co Ltd 免疫力強化剤及び免疫力強化食品
CN1263772C (zh) * 1998-02-17 2006-07-12 宝生物工程株式会社 硫酸糖
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JP3982916B2 (ja) * 1998-07-31 2007-09-26 タカラバイオ株式会社 抗ヘリコバクター・ピロリ剤
AU2007200916B2 (en) * 1998-10-05 2009-09-17 Kabushiki Kaisha Yakult Honsha Antibacterial agents and process for producing the same
CA2346132C (en) * 1998-10-05 2008-02-12 Kabushiki Kaisha Yakult Honsha Antibacterial agents and process for producing the same
CN1098707C (zh) * 1999-07-19 2003-01-15 齐清 含藻蛋白多糖提取物的药物组合物以及藻蛋白多糖的提取
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JP2003155244A (ja) * 2002-09-13 2003-05-27 Kyodo Milk Industry Co Ltd モズク由来のフコイダンを含む食品
JP2006143817A (ja) * 2004-11-17 2006-06-08 South Product:Kk 脱色フコイダンの製造方法
JP2006143816A (ja) * 2004-11-17 2006-06-08 South Product:Kk 脱色フコイダンの製造方法
CN100375755C (zh) * 2005-01-25 2008-03-19 上海中医药大学 一种长叶蜈蚣藻多糖提取物、其制备方法及用途
EP1930012B1 (en) 2005-09-27 2018-05-23 Asahi Kasei Kabushiki Kaisha Cellooligosaccharide-containing composition
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CN101991598A (zh) * 2010-12-06 2011-03-30 吉林省辉南长龙生化药业股份有限公司 褐藻多糖硫酸酯在制备治疗胃肠疾病药物中的用途
JP2011241216A (ja) * 2011-05-23 2011-12-01 Kyodo Milk Industry Co Ltd モズク由来のフコイダンを含む食品
EP2692740A1 (en) * 2012-07-30 2014-02-05 Le Centre National De La Recherche Scientifique Glycan compositions, processes for preparing the same and their uses as a drug
JP6859017B2 (ja) * 2014-10-31 2021-04-14 第一産業株式会社 外用クリーム及びその製造方法
JP6913266B2 (ja) * 2016-03-25 2021-08-04 株式会社クレイ沖縄 フコイダンともろみ酢とを混合した抗腫瘍方法又は物質
CN110731432A (zh) * 2019-11-18 2020-01-31 青岛锦慧盛源生物科技发展有限公司 一种海藻益生元护胃饮料及其制备方法

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Publication number Publication date
ATE193449T1 (de) 2000-06-15
JPH07138166A (ja) 1995-05-30
KR100296089B1 (ko) 2001-10-24
EP0645143B1 (en) 2000-05-31
CN1108572A (zh) 1995-09-20
CA2132150C (en) 2004-05-04
DE69424731D1 (de) 2000-07-06
EP0645143A1 (en) 1995-03-29
DE69424731T2 (de) 2000-09-28
TW438593B (en) 2001-06-07
JP3403496B2 (ja) 2003-05-06
NZ264517A (en) 1995-12-21
AU7418794A (en) 1995-04-06
CA2132150A1 (en) 1995-03-25
CN1096867C (zh) 2002-12-25

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