KR920019933A - 소의 성장 호르몬 유리 인자의 전구체 형태 및 관련 dna화합물 - Google Patents

소의 성장 호르몬 유리 인자의 전구체 형태 및 관련 dna화합물 Download PDF

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Publication number
KR920019933A
KR920019933A KR1019920006371A KR920006371A KR920019933A KR 920019933 A KR920019933 A KR 920019933A KR 1019920006371 A KR1019920006371 A KR 1019920006371A KR 920006371 A KR920006371 A KR 920006371A KR 920019933 A KR920019933 A KR 920019933A
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KR
South Korea
Prior art keywords
seq
growth hormone
bovine growth
related dna
precursor forms
Prior art date
Application number
KR1019920006371A
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English (en)
Inventor
라인 비어만 크리스틴
창 깅
루이스 하이만 마크
맥스웰 시엉 한센
Original Assignee
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 일라이 릴리 앤드 캄파니 filed Critical 일라이 릴리 앤드 캄파니
Publication of KR920019933A publication Critical patent/KR920019933A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

내용 없음

Description

소의 성장 호르몬 유리 인자의 전구체 형태 및 관련 DNA 화합물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1도는 플라스미드 pHS 507의 제한부위 및 작용지도를 도시한 것이다.

Claims (6)

  1. 서열 동정 번호 4를 암호화하는 단리된 DNA서열을 포함하는 DNA 화합물.
  2. 서열 동정 번호 3인 제 1항의 단리된 DNA서열.
  3. 서열 동정 번호 1인 단리된 DNA서열을 포함하는 DNA 화합물.
  4. 서열 동정 번호 4의 폴리펩티드 화합물.
  5. 서열 동정 번호 6의 폴리펩티드 화합물.
  6. 활성화제로서 서열 동정 번호 4를 갖는 폴리펩티드 화합물 또는 그의 약학적으로 허용 가능한 산 또는 카복실산 부가염과 약학적으로 허용 가능한 고상 또는 액상 담체를 포함하는 약학 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개되는 것임.
KR1019920006371A 1991-04-19 1992-04-16 소의 성장 호르몬 유리 인자의 전구체 형태 및 관련 dna화합물 KR920019933A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68835491A 1991-04-19 1991-04-19
US688,354 1991-04-19

Publications (1)

Publication Number Publication Date
KR920019933A true KR920019933A (ko) 1992-11-20

Family

ID=24764090

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920006371A KR920019933A (ko) 1991-04-19 1992-04-16 소의 성장 호르몬 유리 인자의 전구체 형태 및 관련 dna화합물

Country Status (17)

Country Link
EP (1) EP0509831A1 (ko)
JP (1) JPH05227969A (ko)
KR (1) KR920019933A (ko)
CN (1) CN1066193A (ko)
AU (1) AU660665B2 (ko)
BR (1) BR9201408A (ko)
CA (1) CA2066335A1 (ko)
CS (1) CS111292A3 (ko)
FI (1) FI921724A (ko)
HU (1) HUT64594A (ko)
IE (1) IE921248A1 (ko)
IL (1) IL101580A0 (ko)
MX (1) MX9201776A (ko)
NO (1) NO921489L (ko)
NZ (1) NZ242344A (ko)
YU (1) YU40492A (ko)
ZA (1) ZA922695B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2297375A1 (en) * 1997-07-24 1999-02-04 Valentis, Inc. Ghrh expression system and methods of use
CN107253991B (zh) * 2017-05-25 2020-07-28 中山大学 一种基于时间分辨荧光免疫分析技术的斜带石斑鱼生长激素特异性定量检测试剂盒

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844380B (en) * 1983-07-05 1985-01-30 Salk Inst For Biological Studi Dna encoding a grf precursor
EP0213472A1 (en) * 1985-08-12 1987-03-11 Syntex (U.S.A.) Inc. Method for producing fusion proteins
ZA866026B (en) * 1985-08-12 1988-04-27 Syntex Inc Bovine growth hormone releasing factor derivative
FR2622455B1 (fr) * 1987-11-04 1991-07-12 Agronomique Inst Nat Rech Application du facteur de stimulation de la secretion de l'hormone de croissance humaine, de ses fragments actifs et des analogues correspondants, pour augmenter la production laitiere et le poids des nouveau-nes chez les mammiferes
NZ238233A (en) * 1990-05-29 1992-12-23 Lilly Co Eli Dna coding for precursor forms of porcine growth hormone releasing factor (pghrf) and related polypeptides

Also Published As

Publication number Publication date
YU40492A (sh) 1994-06-10
CN1066193A (zh) 1992-11-18
AU1497792A (en) 1992-10-22
NO921489L (no) 1992-10-20
FI921724A (fi) 1992-10-20
HU9201321D0 (en) 1992-07-28
AU660665B2 (en) 1995-07-06
FI921724A0 (fi) 1992-04-16
NO921489D0 (no) 1992-04-14
HUT64594A (en) 1994-01-28
ZA922695B (en) 1993-10-13
JPH05227969A (ja) 1993-09-07
MX9201776A (es) 1992-10-01
NZ242344A (en) 1993-11-25
BR9201408A (pt) 1992-12-01
IL101580A0 (en) 1992-12-30
CA2066335A1 (en) 1992-10-20
CS111292A3 (en) 1992-11-18
IE921248A1 (en) 1992-10-21
EP0509831A1 (en) 1992-10-21

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