KR900000335A - 히드록시알킬시스테인 유도체 및 이를 함유하는 거담제 - Google Patents

히드록시알킬시스테인 유도체 및 이를 함유하는 거담제 Download PDF

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Publication number
KR900000335A
KR900000335A KR1019890008194A KR890008194A KR900000335A KR 900000335 A KR900000335 A KR 900000335A KR 1019890008194 A KR1019890008194 A KR 1019890008194A KR 890008194 A KR890008194 A KR 890008194A KR 900000335 A KR900000335 A KR 900000335A
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KR
South Korea
Prior art keywords
hydroxyalkylcysteine
expectorants
derivatives
same
formula
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Application number
KR1019890008194A
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English (en)
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KR950004676B1 (ko
Inventor
요시꾸니 이또오
히로유끼 미즈노
치까꼬 기요하라
스스무 사또
다쯔히꼬 가또리
Original Assignee
다이도 나오가따
에스에스 세이야꾸 가부시끼 가이샤
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Publication of KR900000335A publication Critical patent/KR900000335A/ko
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Publication of KR950004676B1 publication Critical patent/KR950004676B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

히드록시알킬시스테인 유도체 및 이를 함유하는 거담제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 다음 일반식(1)의 히드록시알킬시스테인 유도체.
    상기식에서, n은 5 내지 24의 정수를 나타낸다.
  2. 다음 일반식(Ⅰ)의 히드록시알킬시스테인 유도체를 함유하는 거담제.
    상기식에서, n은 5 내지 24의 정수를 나타낸다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890008194A 1988-06-16 1989-06-14 히드록시알킬시스테인 유도체 및 이를 함유하는 거담제 KR950004676B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP63148653A JPH0788352B2 (ja) 1988-06-16 1988-06-16 ヒドロキシアルキルシステイン誘導体およびこれを含有する去痰剤
JP63-148653 1988-06-16
JP148653/1988 1988-06-16

Publications (2)

Publication Number Publication Date
KR900000335A true KR900000335A (ko) 1990-01-30
KR950004676B1 KR950004676B1 (ko) 1995-05-04

Family

ID=15457618

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019890008195A KR950004677B1 (ko) 1988-06-16 1989-06-14 히드록시알킬시스테인 유도체 및 이를 함유하는 거담제
KR1019890008194A KR950004676B1 (ko) 1988-06-16 1989-06-14 히드록시알킬시스테인 유도체 및 이를 함유하는 거담제

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1019890008195A KR950004677B1 (ko) 1988-06-16 1989-06-14 히드록시알킬시스테인 유도체 및 이를 함유하는 거담제

Country Status (8)

Country Link
US (2) US5047428A (ko)
EP (2) EP0346883B1 (ko)
JP (1) JPH0788352B2 (ko)
KR (2) KR950004677B1 (ko)
CA (2) CA1312090C (ko)
DE (2) DE68909501T2 (ko)
ES (2) ES2056153T3 (ko)
HK (1) HK125096A (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0788352B2 (ja) * 1988-06-16 1995-09-27 エスエス製薬株式会社 ヒドロキシアルキルシステイン誘導体およびこれを含有する去痰剤
JP4098850B2 (ja) * 1997-07-16 2008-06-11 久光製薬株式会社 Ｓ−（３−ヒドロキシプロピル）−ｌ−システインを含有する経口用製剤
JP2000133368A (ja) 1998-10-20 2000-05-12 Yazaki Corp 防水コネクタとダミー栓の係止構造
JP3805646B2 (ja) * 2001-05-25 2006-08-02 久光メディカル株式会社 医薬液剤
KR20040004638A (ko) * 2001-05-25 2004-01-13 에스에스 세야쿠 가부시키 가이샤 의약 조성물
CN1293867C (zh) * 2001-05-25 2007-01-10 爱诗爱诗制药株式会社 药物复合制剂
JP4490668B2 (ja) * 2003-10-23 2010-06-30 田辺三菱製薬株式会社 下痢治療薬
WO2007040188A1 (ja) * 2005-10-03 2007-04-12 Sankyo Company, Limited 杯細胞過形成抑制のための医薬組成物
GB2460915B (en) * 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor
CN102180820B (zh) * 2011-03-16 2014-03-12 四川科伦药物研究有限公司 一种制备高纯度福多司坦的纯化方法
CN103768011A (zh) * 2012-10-23 2014-05-07 天津药物研究院 福多司坦注射剂及其制备方法
CN103113273B (zh) * 2013-02-01 2014-09-10 浙江国邦药业有限公司 一种福多司坦的合成方法
CN104418779B (zh) * 2013-08-26 2017-08-08 天方药业有限公司 高纯度福多司坦的制备方法
CN104326954B (zh) * 2014-10-17 2016-03-30 宜昌东阳光长江药业股份有限公司 一种福多司坦的合成方法
CN106432021B (zh) * 2016-09-23 2018-03-27 威海迪素制药有限公司 一种福多司坦结晶的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3111M (fr) * 1963-12-02 1965-02-08 Rech S Pharma Et Scient Médicament a base de dérivé de cystéine.
US4085217A (en) * 1964-01-29 1978-04-18 L'oreal Process and cosmetic compositions for the treatment of skin and scalp
US3891749A (en) * 1969-10-07 1975-06-24 Rech Pharm Scientifiques Digestive pharmaceutical composition comprising S-carboxymethyl cysteine for reducing viscosity of respiratory tract secretions, and method of treating therewith
FR2187326B1 (ko) * 1972-06-15 1975-10-17 Rech Pharm Scientifiques
US4005222A (en) * 1975-05-21 1977-01-25 Mead Johnson & Company Mucolytic mercaptoacylamidobenzoic and benzenesulfonic acid compounds and process
ES469060A1 (es) * 1978-04-22 1979-04-01 Invest Tecnica Aplicada Procedimiento para la preparacion de nuevos derivados tio- prenilicos con actividad farmacologica
ES524820A0 (es) * 1983-08-08 1985-02-01 Vinas Lab Procedimiento para la obtencion de un nuevo derivado de carbocisteina
JPH0788352B2 (ja) * 1988-06-16 1995-09-27 エスエス製薬株式会社 ヒドロキシアルキルシステイン誘導体およびこれを含有する去痰剤

Also Published As

Publication number Publication date
EP0346882A2 (en) 1989-12-20
EP0346883A3 (en) 1990-10-10
KR950004677B1 (ko) 1995-05-04
ES2059625T3 (es) 1994-11-16
US5047428A (en) 1991-09-10
EP0346882B1 (en) 1993-09-29
JPH0788352B2 (ja) 1995-09-27
KR900000336A (ko) 1990-01-30
EP0346883A2 (en) 1989-12-20
ES2056153T3 (es) 1994-10-01
DE68909501T2 (de) 1994-05-05
US4906665A (en) 1990-03-06
CA1312090C (en) 1992-12-29
EP0346883B1 (en) 1994-05-18
KR950004676B1 (ko) 1995-05-04
HK125096A (en) 1996-07-19
DE68915341T2 (de) 1995-02-16
JPH023674A (ja) 1990-01-09
DE68915341D1 (de) 1994-06-23
DE68909501D1 (de) 1993-11-04
CA1325597C (en) 1993-12-28
EP0346882A3 (en) 1990-12-12

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