KR840008319A - 시클로헥산디온 유도체의 제조방법 - Google Patents

시클로헥산디온 유도체의 제조방법 Download PDF

Info

Publication number
KR840008319A
KR840008319A KR1019840002146A KR840002146A KR840008319A KR 840008319 A KR840008319 A KR 840008319A KR 1019840002146 A KR1019840002146 A KR 1019840002146A KR 840002146 A KR840002146 A KR 840002146A KR 840008319 A KR840008319 A KR 840008319A
Authority
KR
South Korea
Prior art keywords
cycloalkyl
alkyl
dialkylmalonate
malonate
unsubstituted
Prior art date
Application number
KR1019840002146A
Other languages
English (en)
Other versions
KR910004134B1 (ko
Inventor
라이센웨베르 게르노트 (외 1)
Original Assignee
군터르 벨젤, 뜨리드리히 뢰미쉬
바스프 악팅겟셀샤후트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6197224&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR840008319(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 군터르 벨젤, 뜨리드리히 뢰미쉬, 바스프 악팅겟셀샤후트 filed Critical 군터르 벨젤, 뜨리드리히 뢰미쉬
Publication of KR840008319A publication Critical patent/KR840008319A/ko
Application granted granted Critical
Publication of KR910004134B1 publication Critical patent/KR910004134B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/20—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hydrogen atoms and substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D309/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
    • C07C2601/20—Systems containing only non-condensed rings with a ring being at least seven-membered the ring being twelve-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

내용 없음.

Description

시클로헥산디온 유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 다음 일반식(Ⅱ)의 α,β-불포화케톤을 염기의 존재하에 디알킬말로네이트와 반응시켜 다음 일반식(Ⅲ)의 알콕시카보닐시클로헥세놀론 또는 그것을 염을 얻고 얻어진(Ⅲ)의 화합물을 아실화, 가수분해 및 탈카복실화시키며, 여기서 1) α,β-불포화케톤(Ⅱ)을 염기의 존재하에 말로네이트를 증류해 낼 수 있는 것으로부터 유리된 알코로부터 선택한 용매중에서 디알킬말로네이트와 반응시키고, 2) 알콜을 공비물이 되기에 적당한 단계에서 증류해내고, 3) R2가 탄소원자이상이 아닌 알킬을 나타내는 R2COHal식의 카복실린산할리드로 알콕시카보닐시클로핵세놀론의 염을 반응시키고, 4) 과량의 아실할리드의 제거후 적당한 단계에서 생성물질을 아실화촉매로 처리하고, 그리고 5) 이 생성물을 가수분해하고 탈탄산화시킴을 특징으로 하는 다음 일반식(Ⅰ)의 시클로헥산디온 유도체의 제조방법.
    상기식에서 R1C2-C8-알킬, C2-C8-알케닐, C3-C12-시클로알킬, 0-4개의 올레핀적으로 불포화 결합을 한 C5-C12-시클로알킬, C2-C8-알킬티오알킬, 0-3계의 올레핀적으로 불포화결합하거나, 치환하지 않은 또는 치환된 또는 헤트아릴로 된 C6-C12-비시클로 또는 포하되거나 올레핀적으로 포화되지 않은 기로 3이상이 아닌 O, S 및 N로부터 선택된 헤테로-원자일 수 있는 4 내지 7원자의 헤테로 고리를 나타내며 R2는 6탄소원자이상이 아닌 알킬기이며 R은 말로네이트의 알콜기이다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840002146A 1983-04-23 1984-04-23 시클로헥산디온 유도체의 제조방법 KR910004134B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833314816 DE3314816A1 (de) 1983-04-23 1983-04-23 Verfahren zur herstellung von cyclohexandionderivaten
DEP3314816.3 1983-04-23

Publications (2)

Publication Number Publication Date
KR840008319A true KR840008319A (ko) 1984-12-14
KR910004134B1 KR910004134B1 (ko) 1991-06-22

Family

ID=6197224

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840002146A KR910004134B1 (ko) 1983-04-23 1984-04-23 시클로헥산디온 유도체의 제조방법

Country Status (13)

Country Link
US (1) US5118856A (ko)
EP (1) EP0124041B2 (ko)
JP (1) JPH064556B2 (ko)
KR (1) KR910004134B1 (ko)
AT (1) ATE16587T1 (ko)
BR (1) BR8401860A (ko)
CA (1) CA1280756C (ko)
DD (1) DD215529A5 (ko)
DE (2) DE3314816A1 (ko)
ES (1) ES531835A0 (ko)
IL (1) IL71585A0 (ko)
SU (1) SU1450733A3 (ko)
UA (1) UA7020A1 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3543447A1 (de) * 1985-12-09 1987-06-11 Basf Ag Cyclohexenonderivate, verfahren zu ihrer herstellung und ihre verwendung als herbizide und das pflanzenwachstum regulierende mittel
DE3600642A1 (de) * 1986-01-11 1987-07-16 Basf Ag Cyclohexenonderivate, verfahren zu ihrer herstellung und ihre verwendung als herbizide mittel
US4945178A (en) * 1986-02-03 1990-07-31 Eastman Kodak Company Preparation of 4-carboalkoxy-1,3-cyclohexanedione type compounds
EP0233117B1 (en) * 1986-02-03 1992-01-29 EASTMAN KODAK COMPANY (a New Jersey corporation) Preparation of 4-carboalkoxy-1,3-cyclohexanedione type compounds
CN101205207B (zh) * 2006-12-18 2010-12-15 中国石油天然气集团公司 [6-（2-乙硫基丙基）-2，4-二氧代-3-丙酰基]环己基甲酸乙酯的合成方法
WO2011062964A1 (en) * 2009-11-17 2011-05-26 University Of Rochester Compounds and methods for altering lifespan of eukaryotic organisms
CN111233720A (zh) * 2018-11-28 2020-06-05 沈阳科创化学品有限公司 一种丙三酮的提纯方法以及烯草酮的制备方法
CN112679330B (zh) * 2020-12-24 2022-07-05 西安向阳航天材料股份有限公司 一种丁二酰丁二酸二甲酯的水解工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950420A (en) * 1973-08-15 1976-04-13 Nippon Soda Company, Ltd. Cyclohexane derivatives
JPS51125738A (en) * 1974-08-30 1976-11-02 Nippon Soda Co Ltd Cyclohexene insecticides and tickicides
US4115204A (en) * 1977-07-21 1978-09-19 Phillips Petroleum Company Separation of phenol-, cyclohexanone-, and cyclohexylbenzene-containing mixtures employing an N,N-disubstituted amide
US4281204A (en) * 1979-10-05 1981-07-28 Fritzsche Dodge & Olcott Inc. Substituted spirocyclic derivatives
US5006158A (en) * 1984-12-20 1991-04-09 Ici Americas Inc. Certain 2-(2-substituted benzoyl)-1,3-cyclohexanediones

Also Published As

Publication number Publication date
KR910004134B1 (ko) 1991-06-22
ATE16587T1 (de) 1985-12-15
SU1450733A3 (ru) 1989-01-07
DD215529A5 (de) 1984-11-14
JPH064556B2 (ja) 1994-01-19
EP0124041B1 (de) 1985-11-21
JPS601150A (ja) 1985-01-07
IL71585A0 (en) 1984-07-31
DE3460015D1 (en) 1986-01-02
EP0124041A1 (de) 1984-11-07
BR8401860A (pt) 1984-11-27
ES8502966A1 (es) 1985-02-01
CA1280756C (en) 1991-02-26
DE3314816A1 (de) 1984-10-25
EP0124041B2 (de) 1991-11-06
ES531835A0 (es) 1985-02-01
UA7020A1 (uk) 1995-03-31
US5118856A (en) 1992-06-02

Similar Documents

Publication Publication Date Title
KR850006939A (ko) 아실트리펩타이드의 제조방법
KR870007872A (ko) 올레핀 형으로 불포화된 화합물을 팔라듐 촉매로 카르보닐화시키는 방법
KR850700133A (ko) 유기산의 제조방법
KR840008319A (ko) 시클로헥산디온 유도체의 제조방법
ATE107271T1 (de) Verfahren zur herstellung von carbonsäuren.
KR830005092A (ko) 시클로프로판 카르복실산의 새로운 유도체
DE69006045D1 (de) Verfahren zur Herstellung von Carbonsäuren.
GB1411396A (en) Method of preparing esters of carboxylic acids
ATE73753T1 (de) Verfahren zur herstellung von alpha, beta unges|ttigten ketonen.
KR870006084A (ko) N-포르밀-α-L-아스파틸-L-페닐알라닌 메틸 에스테르의 제조방법
KR940011422A (ko) 방향족 알데하이드의 제조방법
KR830007492A (ko) 프로필렌의 선택성 하이드로 카복실화로 이소부티르산을 제조하는 방법
KR840007556A (ko) 방향족 히드록시카르복시산 벤질 에스테르의 제조방법
ATE224349T1 (de) Verfahren zur herstellung von höheren ungesättigten ketonen
KR830008489A (ko) N-아실 아미노산 유도체의 제조방법
KR870009978A (ko) 알파, 베타-불포화 카보닐 화합물의 촉매적 가수분해 방법
ATE4118T1 (de) Verfahren zur herstellung von 17 alpha-hydroxyund 17a alpha-hydroxy-d-homo-etiocarbonsaeuren.
KR890014428A (ko) 이성질 알데히드의 혼합물로부터 2-메틸알칸알을 회수하는 방법
KR900001706A (ko) 테이코플라닌 화합물의 n15,n15-디알킬 유도체의 제조방법
KR830007668A (ko) 6-아미노페니실란산 유도체의 제조방법
ATE3969T1 (de) Verfahren zur herstellung von essigsaeure durch carbonylierung.
KR940003950A (ko) 다가 페놀 화합물의 제조방법
ATE3850T1 (de) Verfahren zur herstellung von essigsaeure durch carbonylierung.
ATE46497T1 (de) Verfahren zur herstellung von wasserfreien carbonsaeuren aus alkoholen.
KR950700246A (ko) E형 프로스타글라딘류의 제조방법

Legal Events

Date Code Title Description
A201 Request for examination
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20030520

Year of fee payment: 13

EXPY Expiration of term