KR20210143254A - 마취 조성물 및 안구의 마취 방법 - Google Patents

마취 조성물 및 안구의 마취 방법 Download PDF

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Publication number
KR20210143254A
KR20210143254A KR1020217034148A KR20217034148A KR20210143254A KR 20210143254 A KR20210143254 A KR 20210143254A KR 1020217034148 A KR1020217034148 A KR 1020217034148A KR 20217034148 A KR20217034148 A KR 20217034148A KR 20210143254 A KR20210143254 A KR 20210143254A
Authority
KR
South Korea
Prior art keywords
composition
articaine
mannitol
borate
complex
Prior art date
Application number
KR1020217034148A
Other languages
English (en)
Korean (ko)
Inventor
마틴 우람
Original Assignee
마틴 우람
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2019/024239 external-priority patent/WO2019191200A1/en
Application filed by 마틴 우람 filed Critical 마틴 우람
Publication of KR20210143254A publication Critical patent/KR20210143254A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020217034148A 2019-03-26 2020-03-16 마취 조성물 및 안구의 마취 방법 KR20210143254A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962824207P 2019-03-26 2019-03-26
US62/824,207 2019-03-26
USPCT/US2019/024239 2019-03-27
PCT/US2019/024239 WO2019191200A1 (en) 2018-03-27 2019-03-27 Method and formulation for producing anesthesia of internal aspect of eye wall by topical application
US16/811,798 US11096922B2 (en) 2018-03-27 2020-03-06 Anesthetic composition and method of anesthetizing the eye
US16/811,798 2020-03-06
PCT/US2020/022915 WO2020197816A1 (en) 2019-03-26 2020-03-16 Anesthetic composition and method of anesthetizing the eye

Publications (1)

Publication Number Publication Date
KR20210143254A true KR20210143254A (ko) 2021-11-26

Family

ID=72609654

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217034148A KR20210143254A (ko) 2019-03-26 2020-03-16 마취 조성물 및 안구의 마취 방법

Country Status (11)

Country Link
EP (1) EP3946311A4 (zh)
JP (1) JP2022527621A (zh)
KR (1) KR20210143254A (zh)
CN (1) CN114072139A (zh)
AU (1) AU2020245203A1 (zh)
BR (1) BR112021019039A2 (zh)
CA (1) CA3134531A1 (zh)
IL (1) IL286624A (zh)
MX (1) MX2021011589A (zh)
SG (1) SG11202110423UA (zh)
WO (1) WO2020197816A1 (zh)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69333850T3 (de) * 1992-05-06 2011-03-17 Alcon Laboratories, Inc., Fort Worth Anwendung von boral-polyol-komplexen für ophthalmische arzneizusammensetzungen
ES2383003T3 (es) * 2001-11-21 2012-06-15 Carl Zeiss Meditec Sas Composición para estabilizar ácido hialurónico
CN101695488B (zh) * 2009-11-05 2012-05-02 蚌埠丰原涂山制药有限公司 复方阿替卡因注射用冻干制剂及其制备方法
CN101721407B (zh) * 2009-11-23 2013-04-10 蚌埠丰原涂山制药有限公司 复方盐酸阿替卡因注射液及其制备方法
FR2968996B1 (fr) * 2010-12-17 2013-04-12 Anteis Sa Formulation aqueuse injectable sterile utilisee en ophtalmologie
FR3036035B1 (fr) * 2015-05-11 2018-10-05 Laboratoires Vivacy Compositions comprenant au moins un polyol et au moins un anesthesique
JP2018526423A (ja) * 2015-09-08 2018-09-13 ビューポイント セラピューティクス， インコーポレイテッド 眼科疾患を処置するための化合物および製剤
WO2018220283A1 (fr) * 2017-05-29 2018-12-06 Kh Medtech Sarl Composition injectable sterile contenant de l'acide hyaluronique reticule et de l'articaine

Also Published As

Publication number Publication date
CA3134531A1 (en) 2020-10-01
IL286624A (en) 2021-10-31
WO2020197816A1 (en) 2020-10-01
MX2021011589A (es) 2021-12-15
EP3946311A4 (en) 2022-12-28
SG11202110423UA (en) 2021-10-28
AU2020245203A1 (en) 2021-11-11
BR112021019039A2 (pt) 2021-11-30
JP2022527621A (ja) 2022-06-02
EP3946311A1 (en) 2022-02-09
CN114072139A (zh) 2022-02-18

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