KR101857694B1 - 항미생물성 화합물 및 이의 제조 방법 및 사용 방법 - Google Patents

항미생물성 화합물 및 이의 제조 방법 및 사용 방법 Download PDF

Info

Publication number: KR101857694B1
Authority: KR; South Korea
Prior art keywords: alkyl; group; infection; infections; tautomer
Prior art date: 2009-10-16

Application number

KR1020127012702A

Other languages

English (en)

Korean (ko)

Other versions

KR20120099436A (ko

Inventor

에린 엠. 더피

아소케 바타카르지

하드윈 오다우드

실리 첸

마르코 데비보

롱리앙 로우

브라이언 티. 윔벌리

Original Assignee

멜린타 테라퓨틱스, 인크.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-10-16

Filing date

2010-10-15

Publication date

2018-06-19

2010-10-15 Application filed by 멜린타 테라퓨틱스, 인크. filed Critical 멜린타 테라퓨틱스, 인크.

2010-10-15 Priority claimed from PCT/US2010/052924 external-priority patent/WO2011047320A2/en

2012-09-10 Publication of KR20120099436A publication Critical patent/KR20120099436A/ko

2018-06-19 Application granted granted Critical

2018-06-19 Publication of KR101857694B1 publication Critical patent/KR101857694B1/ko

Links

0 CB*C1=*N2[U]C(**F)=C(*NI)**2=*C1=NCC Chemical compound CB*C1=*N2[U]C(**F)=C(*NI)**2=*C1=NCC 0.000 description 12
FROBXVZUJSFYRM-UHFFFAOYSA-N CC(CC1)CCC1C(NCCNC(N)=N)=O Chemical compound CC(CC1)CCC1C(NCCNC(N)=N)=O FROBXVZUJSFYRM-UHFFFAOYSA-N 0.000 description 1
YGCUYAYNBTVVIR-UHFFFAOYSA-N CCCC1CCN(CCCCCNC(N)=N)CCC1 Chemical compound CCCC1CCN(CCCCCNC(N)=N)CCC1 YGCUYAYNBTVVIR-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pathology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Medical Informatics (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Engineering & Computer Science (AREA)
Surgery (AREA)
Physics & Mathematics (AREA)
Ophthalmology & Optometry (AREA)
Otolaryngology (AREA)
Vascular Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Materials For Medical Uses (AREA)
Plural Heterocyclic Compounds (AREA)

KR1020127012702A 2009-10-16 2010-10-15 항미생물성 화합물 및 이의 제조 방법 및 사용 방법 KR101857694B1 (ko)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US25247809P	2009-10-16	2009-10-16
US61/252,478		2009-10-16
US31428710P	2010-03-16	2010-03-16
US61/314,287		2010-03-16
US35820110P	2010-06-24	2010-06-24
US61/358,201		2010-06-24
PCT/US2010/052924 WO2011047320A2 (en)	2009-10-16	2010-10-15	Antimicrobial compounds and methods of making and using the same

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1020187013069A Division KR20180051676A (ko)	2009-10-16	2010-10-15	항미생물성 화합물 및 이의 제조 방법 및 사용 방법

Publications (2)

Publication Number	Publication Date
KR20120099436A KR20120099436A (ko)	2012-09-10
KR101857694B1 true KR101857694B1 (ko)	2018-06-19

Family

ID=43876906

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
KR1020127012676A KR20120101392A (ko)	2009-10-16	2010-10-15	항미생물성 화합물 및 이의 제조 방법 및 사용 방법
KR1020127012702A KR101857694B1 (ko)	2009-10-16	2010-10-15	항미생물성 화합물 및 이의 제조 방법 및 사용 방법
KR1020127012700A KR20120099435A (ko)	2009-10-16	2010-10-15	항미생물성 화합물 및 이의 제조 방법 및 사용 방법

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
KR1020127012676A KR20120101392A (ko)	2009-10-16	2010-10-15	항미생물성 화합물 및 이의 제조 방법 및 사용 방법

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
KR1020127012700A KR20120099435A (ko)	2009-10-16	2010-10-15	항미생물성 화합물 및 이의 제조 방법 및 사용 방법

Country Status (9)

Country	Link
JP (6)	JP2016121171A (zh)
KR (3)	KR20120101392A (zh)
CN (5)	CN108456211A (zh)
AR (3)	AR080559A1 (zh)
EA (1)	EA201500913A1 (zh)
MY (2)	MY161870A (zh)
NZ (2)	NZ713357A (zh)
SG (3)	SG10201406635QA (zh)
TW (8)	TWI618707B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG10201406635QA (en) *	2009-10-16	2014-11-27	Melinta Therapeutics Inc	Antimicrobial compounds and methods of making and using the same
WO2011047323A2 (en)	2009-10-16	2011-04-21	Rib-X Pharmaceuticals, Inc.	Antimicrobial compounds and methods of making and using the same
KR20180051676A (ko)	2009-10-16	2018-05-16	멜린타 테라퓨틱스, 인크.	항미생물성 화합물 및 이의 제조 방법 및 사용 방법
CN109053695A (zh) *	2011-04-15	2018-12-21	梅琳塔治疗公司	抗微生物化合物及制备和使用所述化合物的方法
CA2923214A1 (en)	2013-09-09	2015-03-12	Melinta Therapeutics, Inc.	Antimicrobial compounds and methods of making and using the same
US9937183B2 (en)	2013-09-09	2018-04-10	Melinta Therapeutics, Inc.	Antimicrobial compounds and methods of making and using the same
EA201792006A1 (ru)	2015-03-11	2018-04-30	Мелинта Терапьютикс, Инк.	Антимикробные соединения и способы их получения и их применение

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2010
- 2010-10-15 SG SG10201406635QA patent/SG10201406635QA/en unknown
- 2010-10-15 SG SG10201406631TA patent/SG10201406631TA/en unknown
- 2010-10-15 EA EA201500913A patent/EA201500913A1/ru unknown
- 2010-10-15 SG SG10201406634VA patent/SG10201406634VA/en unknown
- 2010-10-15 NZ NZ713357A patent/NZ713357A/en not_active IP Right Cessation
- 2010-10-15 TW TW104135849A patent/TWI618707B/zh not_active IP Right Cessation
- 2010-10-15 TW TW099135283A patent/TWI589294B/zh not_active IP Right Cessation
- 2010-10-15 KR KR1020127012676A patent/KR20120101392A/ko active Application Filing
- 2010-10-15 MY MYPI2012001696A patent/MY161870A/en unknown
- 2010-10-15 TW TW106101234A patent/TW201726630A/zh unknown
- 2010-10-15 CN CN201810372366.XA patent/CN108456211A/zh active Pending
- 2010-10-15 KR KR1020127012702A patent/KR101857694B1/ko active IP Right Grant
- 2010-10-15 TW TW99135286A patent/TW201125566A/zh unknown
- 2010-10-15 TW TW104131806A patent/TWI621439B/zh not_active IP Right Cessation
- 2010-10-15 NZ NZ623384A patent/NZ623384A/en not_active IP Right Cessation
- 2010-10-15 TW TW099135287A patent/TWI612048B/zh not_active IP Right Cessation
- 2010-10-15 CN CN201710499962.XA patent/CN107266470A/zh active Pending
- 2010-10-15 MY MYPI2012001651A patent/MY165011A/en unknown
- 2010-10-15 KR KR1020127012700A patent/KR20120099435A/ko not_active Application Discontinuation
- 2010-10-15 TW TW106102658A patent/TWI629277B/zh not_active IP Right Cessation
- 2010-10-15 CN CN201610065325.7A patent/CN105646370A/zh active Pending
- 2010-10-15 CN CN201710499688.6A patent/CN107445976A/zh active Pending
- 2010-10-15 TW TW106131448A patent/TW201825495A/zh unknown
- 2010-10-15 CN CN201510018490.2A patent/CN104628729B/zh not_active Expired - Fee Related
- 2010-10-18 AR ARP100103805 patent/AR080559A1/es unknown
- 2010-10-18 AR ARP100103804 patent/AR080558A1/es unknown
- 2010-10-18 AR ARP100103803 patent/AR080617A1/es unknown
2016
- 2016-01-29 JP JP2016015912A patent/JP2016121171A/ja active Pending
- 2016-02-29 JP JP2016037911A patent/JP2016153405A/ja not_active Withdrawn
- 2016-03-17 JP JP2016054375A patent/JP2016172733A/ja not_active Withdrawn
2017
- 2017-07-31 JP JP2017148530A patent/JP2018024653A/ja active Pending
- 2017-07-31 JP JP2017148521A patent/JP2018039784A/ja active Pending
2018
- 2018-09-27 JP JP2018182217A patent/JP2019038808A/ja active Pending

Patent Citations (1)

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Publication number	Priority date	Publication date	Assignee	Title
WO2000012484A1 (de) *	1998-08-27	2000-03-09	Bayer Aktiengesellschaft	Tan-1057 derivate

Also Published As

Publication number	Publication date
TW201726630A (zh)	2017-08-01
CN104628729A (zh)	2015-05-20
CN107445976A (zh)	2017-12-08
JP2016121171A (ja)	2016-07-07
JP2018039784A (ja)	2018-03-15
AR080617A1 (es)	2012-04-25
TW201125564A (en)	2011-08-01
TW201825495A (zh)	2018-07-16
TWI589294B (zh)	2017-07-01
AR080558A1 (es)	2012-04-18
TW201622725A (zh)	2016-07-01
TW201630914A (zh)	2016-09-01
TW201125566A (en)	2011-08-01
AR080559A1 (es)	2012-04-18
EA201500913A1 (ru)	2015-12-30
NZ713357A (en)	2017-05-26
CN107266470A (zh)	2017-10-20
JP2016153405A (ja)	2016-08-25
TW201124417A (en)	2011-07-16
MY161870A (en)	2017-05-15
TWI629277B (zh)	2018-07-11
SG10201406635QA (en)	2014-11-27
CN108456211A (zh)	2018-08-28
TWI618707B (zh)	2018-03-21
NZ623384A (en)	2016-06-24
TW201731849A (zh)	2017-09-16
CN104628729B (zh)	2018-11-06
MY165011A (en)	2018-02-28
KR20120099436A (ko)	2012-09-10
TWI612048B (zh)	2018-01-21
JP2018024653A (ja)	2018-02-15
JP2019038808A (ja)	2019-03-14
JP2016172733A (ja)	2016-09-29
KR20120101392A (ko)	2012-09-13
CN105646370A (zh)	2016-06-08
KR20120099435A (ko)	2012-09-10
SG10201406634VA (en)	2014-11-27
SG10201406631TA (en)	2014-11-27
TWI621439B (zh)	2018-04-21

Legal Events

Date	Code	Title
2012-06-29	AMND	Amendment
2015-10-13	A201	Request for examination
2015-10-13	AMND	Amendment
2016-11-07	E902	Notification of reason for refusal
2017-05-08	AMND	Amendment
2017-09-28	E601	Decision to refuse application
2018-01-08	AMND	Amendment
2018-02-07	X701	Decision to grant (after re-examination)
2018-05-08	A107	Divisional application of patent
2018-05-08	GRNT	Written decision to grant

Publication	Publication Date	Title
KR101972992B1 (ko)	2019-04-29	항미생물성 화합물 및 이의 제조 방법 및 사용 방법
US9845297B2 (en)	2017-12-19	Antimicrobial compounds and methods of making and using the same
US10259825B2 (en)	2019-04-16	Antimicrobial compounds and methods of making and using the same
KR101857694B1 (ko)	2018-06-19	항미생물성 화합물 및 이의 제조 방법 및 사용 방법
US11098047B2 (en)	2021-08-24	Antimicrobials and methods of making and using same