KR0154209B1 - Improved chemilluminescent 1,2-dioxetanes - Google Patents
Improved chemilluminescent 1,2-dioxetanesInfo
- Publication number
- KR0154209B1 KR0154209B1 KR1019950700026A KR19950700026A KR0154209B1 KR 0154209 B1 KR0154209 B1 KR 0154209B1 KR 1019950700026 A KR1019950700026 A KR 1019950700026A KR 19950700026 A KR19950700026 A KR 19950700026A KR 0154209 B1 KR0154209 B1 KR 0154209B1
- Authority
- KR
- South Korea
- Prior art keywords
- ring
- dioxetane
- dioxetanes
- substituent
- group
- Prior art date
Links
- BVTJGGGYKAMDBN-UHFFFAOYSA-N Dioxetane Chemical class C1COO1 BVTJGGGYKAMDBN-UHFFFAOYSA-N 0.000 title abstract 7
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 2
- 125000001624 naphthyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
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- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
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- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- General Engineering & Computer Science (AREA)
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- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Luminescent Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/057,903 US5538847A (en) | 1989-07-17 | 1993-05-07 | Chemiluminescent 1,2-dioxetanes |
US057903 | 1993-05-07 | ||
US08/231,673 US5582980A (en) | 1989-07-17 | 1994-04-25 | Chemiluminescent 1,2-dioxetanes |
US231673 | 1994-04-25 | ||
PCT/US1994/004555 WO1994026726A1 (en) | 1993-05-07 | 1994-05-06 | Improved chemiluminescent 1,2-dioxetanes |
Publications (2)
Publication Number | Publication Date |
---|---|
KR950702546A KR950702546A (ko) | 1995-07-29 |
KR0154209B1 true KR0154209B1 (en) | 1998-11-16 |
Family
ID=26737008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950700026A KR0154209B1 (en) | 1993-05-07 | 1995-01-05 | Improved chemilluminescent 1,2-dioxetanes |
Country Status (11)
Country | Link |
---|---|
US (3) | US5582980A (ko) |
EP (3) | EP0649417B1 (ko) |
JP (1) | JP2837276B2 (ko) |
KR (1) | KR0154209B1 (ko) |
AT (3) | ATE205839T1 (ko) |
AU (2) | AU676327B2 (ko) |
CA (1) | CA2139348C (ko) |
DE (3) | DE69434940T2 (ko) |
FI (1) | FI950075A0 (ko) |
NO (2) | NO309143B1 (ko) |
WO (1) | WO1994026726A1 (ko) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE36536E (en) * | 1986-07-24 | 2000-01-25 | Tropix. Inc. | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes |
WO1988000695A1 (en) | 1986-07-24 | 1988-01-28 | Quest Systems, Inc. | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes |
US6022964A (en) | 1989-07-17 | 2000-02-08 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
US5603868A (en) * | 1992-10-30 | 1997-02-18 | Abbott Laboratories | Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes |
JPH09507571A (ja) * | 1993-12-23 | 1997-07-29 | トロピックス・インコーポレーテッド | 化学発光エネルギー移動検定 |
US5631167A (en) * | 1995-07-31 | 1997-05-20 | Bayer Corporation | Capsule chemistry analytical methods employing dioxetane chemiluminescence |
US5777135A (en) * | 1995-07-31 | 1998-07-07 | Lumigen, Inc. | Di-substituted 1,2-dioxetane compounds having increased water solubility and assay compositions |
US5721370A (en) * | 1995-07-31 | 1998-02-24 | Lumigen Inc. | Water soluble tri-substituted 1,2-dioxetane compounds and assay compositions having increased storage stability |
AU708266B2 (en) * | 1995-10-17 | 1999-07-29 | Applied Biosystems, Llc | 1,2 chemiluminescent dioxetanes of improved performance |
US5783381A (en) * | 1995-10-19 | 1998-07-21 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
US5834456A (en) * | 1996-02-23 | 1998-11-10 | The Dow Chemical Company | Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents |
DE69834077T2 (de) * | 1997-01-14 | 2006-08-24 | Daicel Chemical Industries, Ltd., Sakai | Nitrierungs- oder carboxylierungskatalysatoren |
US6660529B2 (en) | 1998-07-28 | 2003-12-09 | Pe Corporation | Heteroaryl substituted benzothiazole dioxetanes |
CA2338883A1 (en) | 1998-07-28 | 2000-02-10 | Tropix, Inc. | Benzothiazole dioxetanes |
US6555698B1 (en) * | 1998-11-17 | 2003-04-29 | Tropix, Inc. | Chemiluminescent substrates for neuraminidase, assays for detection of neuraminidase and kits therefor |
EP1151090B1 (en) * | 1998-12-15 | 2009-09-02 | Applera Corporation | Multiple enzyme assays |
CA2370520A1 (en) * | 1999-04-16 | 2000-10-26 | Komandoor Elayavalli Achyuthan | Viral detection method using viral encoded enzymes and chemiluminescent substrates |
US6893827B1 (en) * | 2000-02-07 | 2005-05-17 | Applera Corporation | Receptor function assay for G-protein coupled receptors and orphan receptors by reporter enzyme mutant complementation |
JP3975167B2 (ja) * | 2001-01-08 | 2007-09-12 | アプレーラ コーポレイション | 樹状化学発光基質 |
US7368296B2 (en) * | 2002-01-17 | 2008-05-06 | Applied Biosystems | Solid phases optimized for chemiluminescent detection |
WO2004072299A1 (en) * | 2003-02-12 | 2004-08-26 | Promega Corporation | Methods and kits for dual enzymatic assays whereby light is quenched from luminescent reactions |
US7390670B2 (en) * | 2003-02-20 | 2008-06-24 | Lumigen, Inc. | Signalling compounds and methods for detecting hydrogen peroxide |
US20060079699A1 (en) * | 2004-08-27 | 2006-04-13 | Brooks Edwards | Intermediate compounds and methods for synthesizing chemiluminescent dioxetane substrates |
WO2006029302A2 (en) * | 2004-09-09 | 2006-03-16 | Applera Corporation | Dioxetane-nanoparticle assemblies for energy transfer detection systems, methods of making the assemblies, and methods of using the assemblies in bioassays |
US7451802B2 (en) * | 2006-01-25 | 2008-11-18 | Nabco Entrances, Inc. | Slidable door assemblies with automatic pivot latching |
JP2007225547A (ja) * | 2006-02-27 | 2007-09-06 | Fujifilm Corp | 標的物質の疎水部位の検出方法 |
US20080248511A1 (en) * | 2007-03-26 | 2008-10-09 | Promega Corporation | Methods to quench light from optical reactions |
CN101462316A (zh) * | 2007-12-19 | 2009-06-24 | 维斯塔斯风力***有限公司 | 预成型件的制备方法 |
WO2010101839A2 (en) | 2009-03-02 | 2010-09-10 | Life Technologies Corporation | Chemiluminescent compositions, methods, assays and kits for oxidative enzymes |
EP2590958B1 (en) | 2010-07-08 | 2015-08-26 | Life Technologies Corporation | In situ chemiluminescent substrates and assays |
EP2705031B1 (en) * | 2011-05-03 | 2018-04-11 | Life Technologies Corporation | Flash and glow 1,2-dioxetanes |
CN103772433A (zh) * | 2012-10-18 | 2014-05-07 | 深圳市美凯特科技有限公司 | 一种用于免疫分析的化学发光试剂amppd的合成方法 |
CN103073589A (zh) * | 2012-12-30 | 2013-05-01 | 杭州师范大学 | 一种1,2-二氧环乙烷类化合物的合成方法 |
CN104557890A (zh) * | 2015-01-12 | 2015-04-29 | 王国平 | 一种碳碳氧氧四元环化合物及其在质谱检测中的应用 |
DE102016119810A1 (de) | 2016-10-18 | 2018-04-19 | Hamilton Bonaduz Ag | Schichten zum Nachweis von Sauerstoff |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1521089A (en) * | 1975-11-12 | 1978-08-09 | Valeas Srl | Aminoethanol derivatives |
WO1984000750A1 (en) * | 1982-08-23 | 1984-03-01 | Univ Australian | Process for the preparation of 3-amino-5-hydroxybenzoic acids and derivatives and analogues thereof |
US4983779A (en) * | 1986-07-17 | 1991-01-08 | The Board Of Governors Of Wayne State University | Process for the preparation of vinyl ethers |
US5616729A (en) * | 1986-07-17 | 1997-04-01 | Board Of Governors Of Wayne State University | Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers |
US5112960A (en) * | 1989-07-17 | 1992-05-12 | Bronstein Irena Y | Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes |
CA1340590C (en) * | 1986-07-24 | 1999-06-08 | John C. Voyta | Chemiluminescence enhancement |
US4931223A (en) * | 1986-07-24 | 1990-06-05 | Tropix, Inc. | Methods of using chemiluminescent 1,2-dioxetanes |
US4978614A (en) * | 1988-10-26 | 1990-12-18 | Tropix, Inc. | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes |
US4956477A (en) * | 1987-12-31 | 1990-09-11 | Tropix, Inc. | Synthesis of 1,2-dioxetanes |
US5220005A (en) * | 1986-07-24 | 1993-06-15 | Tropix, Inc. | Substituted adamantyl dioxetanes |
US5089630A (en) * | 1987-12-31 | 1992-02-18 | Bronstein Irena Y | Dioxetanes for use in assays |
US5538847A (en) * | 1989-07-17 | 1996-07-23 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
US5330900A (en) * | 1987-12-31 | 1994-07-19 | Tropix, Inc. | Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes |
US4952707A (en) * | 1988-06-30 | 1990-08-28 | Tropix, Inc. | Enzymatically-cleavable chemiluminescent fused polycyclic ring-containing 1,2-dioxetanes |
US5132204A (en) * | 1989-05-31 | 1992-07-21 | Chiron Corporation | Chemiluminescent double-triggered 1, 2-dioxetanes |
US5326882A (en) * | 1989-07-17 | 1994-07-05 | Tropix, Inc. | Chemiluminescent 3-(substituted Adamant-2'-Ylidene) 1,2-dioxetanes |
AU656927B2 (en) * | 1990-08-30 | 1995-02-23 | Applied Biosystems, Llc | Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes |
US5336596A (en) * | 1991-12-23 | 1994-08-09 | Tropix, Inc. | Membrane for chemiluminescent blotting applications |
US5603868A (en) * | 1992-10-30 | 1997-02-18 | Abbott Laboratories | Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes |
-
1994
- 1994-04-25 US US08/231,673 patent/US5582980A/en not_active Expired - Lifetime
- 1994-05-06 DE DE69434940T patent/DE69434940T2/de not_active Expired - Lifetime
- 1994-05-06 AT AT94915887T patent/ATE205839T1/de not_active IP Right Cessation
- 1994-05-06 AT AT01104599T patent/ATE334996T1/de not_active IP Right Cessation
- 1994-05-06 JP JP6525458A patent/JP2837276B2/ja not_active Expired - Lifetime
- 1994-05-06 DE DE69434814T patent/DE69434814T2/de not_active Expired - Lifetime
- 1994-05-06 AU AU67741/94A patent/AU676327B2/en not_active Expired
- 1994-05-06 EP EP94915887A patent/EP0649417B1/en not_active Expired - Lifetime
- 1994-05-06 EP EP01104600A patent/EP1120423B1/en not_active Expired - Lifetime
- 1994-05-06 EP EP01104599A patent/EP1120422B1/en not_active Expired - Lifetime
- 1994-05-06 WO PCT/US1994/004555 patent/WO1994026726A1/en active IP Right Grant
- 1994-05-06 CA CA002139348A patent/CA2139348C/en not_active Expired - Lifetime
- 1994-05-06 DE DE69428321T patent/DE69428321T2/de not_active Expired - Lifetime
- 1994-05-06 AT AT01104600T patent/ATE356822T1/de not_active IP Right Cessation
-
1995
- 1995-01-05 KR KR1019950700026A patent/KR0154209B1/ko not_active IP Right Cessation
- 1995-01-05 FI FI950075A patent/FI950075A0/fi unknown
- 1995-01-06 NO NO950065A patent/NO309143B1/no not_active IP Right Cessation
- 1995-10-17 US US08/544,172 patent/US5840919A/en not_active Expired - Lifetime
-
1996
- 1996-01-19 US US08/588,810 patent/US5851771A/en not_active Expired - Fee Related
-
1997
- 1997-06-06 AU AU24749/97A patent/AU695229B2/en not_active Expired
-
2000
- 2000-07-06 NO NO20003485A patent/NO20003485D0/no not_active Application Discontinuation
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