JPWO2005018693A1 - コンタクトレンズ用液剤 - Google Patents
コンタクトレンズ用液剤 Download PDFInfo
- Publication number
- JPWO2005018693A1 JPWO2005018693A1 JP2005513242A JP2005513242A JPWO2005018693A1 JP WO2005018693 A1 JPWO2005018693 A1 JP WO2005018693A1 JP 2005513242 A JP2005513242 A JP 2005513242A JP 2005513242 A JP2005513242 A JP 2005513242A JP WO2005018693 A1 JPWO2005018693 A1 JP WO2005018693A1
- Authority
- JP
- Japan
- Prior art keywords
- contact lens
- component
- lens
- agent
- contained
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/141—Biguanides, e.g. chlorhexidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/143—Quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/26—Organic compounds containing oxygen
- C11D7/265—Carboxylic acids or salts thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/32—Organic compounds containing nitrogen
- C11D7/3218—Alkanolamines or alkanolimines
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/32—Organic compounds containing nitrogen
- C11D7/3245—Aminoacids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S134/00—Cleaning and liquid contact with solids
- Y10S134/901—Contact lens
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Animal Behavior & Ethology (AREA)
- Environmental Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pest Control & Pesticides (AREA)
- Public Health (AREA)
- Dentistry (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Eyeglasses (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
Abstract
Description
メニコン製のソフトコンタクトレンズ「メニコンソフトMA」を、上記で得られた各液剤に、4時間浸漬する操作を、30回行なった後、コンタクトレンズ表面を目視で観察し、以下の評価基準で、評価を行なった。なお、各液剤は、1回の浸漬操作毎に、新しいものに取り替えた。
◎:処理前と殆んど変化無し。
○:部分的に結晶や粉状物等の析出物が観測されたが、使用に問題はない程度である。
×:レンズの大部分に析出物が観察された。或いは大きい析出物が観測された。
各液剤の各9.9mLを試験管に入れ、これに、カンジダ・アルビカンス(Candida albicans IFO 1594)を107〜108cfu/mL含む菌液の0.1mLを加えて攪拌し、最終的に105〜106cfu/mLの菌数を含む菌懸濁液を、それぞれ調製した。その後、それらを23℃で、4時間放置した後に、かかる菌懸濁液の1mLを取り出し、ブドウ糖ペプトン寒天培地の20mLを用いて、平板希釈法によりサンプル1mL中の生菌数を測定した。そして、この生菌数から、処理液1mL中の生菌数を算出した後、下記の計算式に従って、対数に換算した菌減少数(log reduction)を求めた。
菌減少数=log(調製直後の菌懸濁液1mL中の生菌数)
−log(処理後の菌懸濁液1mL中の生菌数)
◎:菌減少数が2以上(殺菌効力がかなりある)
○:菌減少数が1以上2未満(殺菌効力がある)
×:菌減少数が1未満(殺菌効力が弱い)
Claims (11)
- ビグアニド系殺菌剤及び4級アンモニウム塩系殺菌剤からなる群より選ばれた少なくとも1種の殺菌剤(A)と、グリコール酸及び/又はアスパラギン酸(B)と、2−アミノ−2−メチル−1,3−プロパンジオール又はその塩(C)とを含有すると共に、該B成分と該C成分が、1:20〜1.3:1のモル比となるように含有せしめられていることを特徴とするコンタクトレンズ用液剤。
- 塩化ナトリウム濃度が、0〜0.2w/w%となるように調整されている請求項1に記載のコンタクトレンズ用液剤。
- 前記A成分が、0.1〜500ppmの濃度となるように含有せしめられている請求項1又は請求項2に記載のコンタクトレンズ用液剤。
- 前記B成分が、0.01〜5w/w%の濃度となるように含有せしめられている請求項1乃至請求項3の何れかに記載のコンタクトレンズ用液剤。
- 中性アミノ酸が、更に含有せしめられている請求項1乃至請求項4の何れかに記載のコンタクトレンズ用液剤。
- 前記中性アミノ酸が、0.1〜4w/w%の濃度となるように含有せしめられている請求項5に記載のコンタクトレンズ用液剤。
- 前記中性アミノ酸が、グリシンである請求項5又は請求項6に記載のコンタクトレンズ用液剤。
- プロピレングリコールが、更に含有せしめられている請求項1乃至請求項7の何れかに記載のコンタクトレンズ用液剤。
- 前記プロピレングリコールが、0.1〜1w/w%の濃度となるように含有せしめられている請求項8に記載のコンタクトレンズ用液剤。
- 界面活性剤及びキレート化剤のうちの少なくとも何れか一方が、更に含有せしめられている請求項1乃至請求項9の何れかに記載のコンタクトレンズ用液剤。
- 対象とするコンタクトレンズが、ソフトコンタクトレンズである請求項1乃至請求項10の何れかに記載のコンタクトレンズ用液剤。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003295863 | 2003-08-20 | ||
JP2003295863 | 2003-08-20 | ||
PCT/JP2004/007923 WO2005018693A1 (ja) | 2003-08-20 | 2004-06-07 | コンタクトレンズ用液剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP3894945B2 JP3894945B2 (ja) | 2007-03-22 |
JPWO2005018693A1 true JPWO2005018693A1 (ja) | 2007-10-04 |
Family
ID=34213571
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005513242A Expired - Lifetime JP3894945B2 (ja) | 2003-08-20 | 2004-06-07 | コンタクトレンズ用液剤 |
Country Status (13)
Country | Link |
---|---|
US (1) | US7199089B2 (ja) |
EP (1) | EP1656955B1 (ja) |
JP (1) | JP3894945B2 (ja) |
CN (1) | CN100457194C (ja) |
AT (1) | ATE371464T1 (ja) |
CY (1) | CY1107020T1 (ja) |
DE (1) | DE602004008651T2 (ja) |
DK (1) | DK1656955T3 (ja) |
ES (1) | ES2293298T3 (ja) |
HK (1) | HK1090855A1 (ja) |
PL (1) | PL1656955T3 (ja) |
PT (1) | PT1656955E (ja) |
WO (1) | WO2005018693A1 (ja) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5135526B2 (ja) * | 2005-06-27 | 2013-02-06 | 株式会社メニコンネクト | コンタクトレンズ用液剤 |
US20070149428A1 (en) | 2005-12-14 | 2007-06-28 | Bausch & Lomb Incorporated | Method of Packaging a Lens |
JPWO2008041439A1 (ja) * | 2006-09-29 | 2010-02-04 | 株式会社メニコン | コンタクトレンズ用液剤 |
US8138156B2 (en) * | 2006-10-18 | 2012-03-20 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
US20080214421A1 (en) * | 2007-02-19 | 2008-09-04 | Fang Zhao | Contact lens care composition |
US8629099B2 (en) * | 2008-03-25 | 2014-01-14 | Bausch & Lomb Incorporated | Ophthalmic compositions comprising a dipeptide |
US8431751B1 (en) | 2008-12-24 | 2013-04-30 | Alcon Research, Ltd. | Polymeric quaternary ammonium compounds with vicinal hydroxy groups |
US9164296B2 (en) * | 2010-11-17 | 2015-10-20 | Menicon Co., Ltd. | Soft contact lens application method, liquid for contact lenses and soft contact lens package |
US8664180B2 (en) | 2012-02-06 | 2014-03-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
US8324171B1 (en) | 2012-02-06 | 2012-12-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
WO2014091574A1 (ja) | 2012-12-12 | 2014-06-19 | 株式会社メニコン | 非イオン性ソフトコンタクトレンズ用消毒液 |
JP6106516B2 (ja) * | 2013-05-08 | 2017-04-05 | 株式会社シード | アカントアメーバ角膜炎の予防剤及び治療剤 |
WO2017094508A1 (ja) * | 2015-11-30 | 2017-06-08 | ロート製薬株式会社 | 眼科組成物 |
CN108697820B (zh) * | 2016-02-17 | 2020-12-22 | 株式会社实瞳 | 抗棘阿米巴接触镜用溶剂 |
CN109381480B (zh) * | 2018-11-15 | 2021-02-09 | 江苏聚锦生物医疗科技有限责任公司 | 复配聚六亚甲基双胍消毒液及其制备方法 |
CN113088411A (zh) * | 2021-04-08 | 2021-07-09 | 山西利普达医药科技有限公司 | 一种含聚季铵盐-1的眼用清洗灭活病毒组合物及其应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0055515B1 (en) | 1980-12-18 | 1985-02-20 | Smith and Nephew Associated Companies p.l.c. | Lens sterilising solutions and their use |
GB2090013B (en) | 1980-12-18 | 1984-04-11 | Smith & Nephew Ass | Soft contact lens sterilising solution |
JP3142245B2 (ja) * | 1996-06-28 | 2001-03-07 | 株式会社資生堂 | 皮膚外用剤 |
JP3698832B2 (ja) | 1996-10-08 | 2005-09-21 | 株式会社メニコン | コンタクトレンズ用液剤 |
JP3745471B2 (ja) * | 1996-11-13 | 2006-02-15 | 株式会社トーメー | コンタクトレンズ用汚れ付着防止組成物及びそれを用いたコンタクトレンズの汚れ付着防止方法 |
WO1998020912A1 (fr) | 1996-11-13 | 1998-05-22 | Tomey Technology Corporation | Composition de traitement pour lentilles de contact et procede de traitement de lentilles de contact au moyen de ladite composition |
JP3745508B2 (ja) | 1997-08-04 | 2006-02-15 | 株式会社トーメー | コンタクトレンズ用液体洗浄組成物及び洗浄方法 |
KR100366676B1 (ko) * | 1996-12-13 | 2003-01-14 | 알콘 래보레이토리스, 인코퍼레이티드 | 안과용 조성물에 저분자량 아미노 알코올을 사용하는 방법 |
US5858346A (en) * | 1997-05-09 | 1999-01-12 | Allergan | Compositions and methods for enhancing contact lens wearability |
JPH11249087A (ja) | 1997-12-18 | 1999-09-17 | Tome:Kk | コンタクトレンズ用液剤 |
AU1180300A (en) * | 1998-11-16 | 2000-06-05 | Rohto Pharmaceutical Co., Ltd. | Liquid ophthalmic preparations |
US7678836B2 (en) * | 1999-11-04 | 2010-03-16 | Fxs Ventures, Llc | Method for rendering a contact lens wettable |
JP2001242428A (ja) * | 1999-12-20 | 2001-09-07 | Tomey Corp | コンタクトレンズ用液剤およびソフトコンタクトレンズの洗浄、消毒、保存方法 |
JP4532720B2 (ja) * | 2000-11-01 | 2010-08-25 | 株式会社メニコンネクト | ソフトコンタクトレンズ用液剤およびソフトコンタクトレンズの洗浄、消毒、保存方法 |
JP4255656B2 (ja) * | 2001-09-17 | 2009-04-15 | 株式会社メニコン | 眼科用液剤及びコンタクトレンズ用液剤 |
JP2003116972A (ja) * | 2001-10-10 | 2003-04-22 | Tomey Corp | 眼科用液剤およびそれを用いた眼用製品の洗浄、消毒、保存方法 |
US20040185028A1 (en) * | 2003-03-19 | 2004-09-23 | Zhenze Hu | Antimicrobial compositions containing ethanolamine buffer and biguanide disinfectant |
-
2004
- 2004-06-07 DE DE602004008651T patent/DE602004008651T2/de not_active Expired - Lifetime
- 2004-06-07 PT PT04745633T patent/PT1656955E/pt unknown
- 2004-06-07 AT AT04745633T patent/ATE371464T1/de active
- 2004-06-07 EP EP04745633A patent/EP1656955B1/en not_active Expired - Lifetime
- 2004-06-07 DK DK04745633T patent/DK1656955T3/da active
- 2004-06-07 PL PL04745633T patent/PL1656955T3/pl unknown
- 2004-06-07 WO PCT/JP2004/007923 patent/WO2005018693A1/ja active IP Right Grant
- 2004-06-07 JP JP2005513242A patent/JP3894945B2/ja not_active Expired - Lifetime
- 2004-06-07 CN CNB2004800236502A patent/CN100457194C/zh not_active Expired - Lifetime
- 2004-06-07 ES ES04745633T patent/ES2293298T3/es not_active Expired - Lifetime
-
2006
- 2006-01-18 US US11/334,080 patent/US7199089B2/en not_active Expired - Lifetime
- 2006-09-20 HK HK06110448A patent/HK1090855A1/xx not_active IP Right Cessation
-
2007
- 2007-11-23 CY CY20071101501T patent/CY1107020T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE602004008651T2 (de) | 2008-06-05 |
ATE371464T1 (de) | 2007-09-15 |
JP3894945B2 (ja) | 2007-03-22 |
DE602004008651D1 (de) | 2007-10-11 |
PT1656955E (pt) | 2007-12-10 |
WO2005018693A1 (ja) | 2005-03-03 |
US7199089B2 (en) | 2007-04-03 |
CN100457194C (zh) | 2009-02-04 |
ES2293298T3 (es) | 2008-03-16 |
EP1656955A4 (en) | 2006-11-02 |
HK1090855A1 (en) | 2007-01-05 |
EP1656955A1 (en) | 2006-05-17 |
CY1107020T1 (el) | 2012-09-26 |
CN1835771A (zh) | 2006-09-20 |
PL1656955T3 (pl) | 2008-01-31 |
DK1656955T3 (da) | 2007-12-27 |
US20060122080A1 (en) | 2006-06-08 |
EP1656955B1 (en) | 2007-08-29 |
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