JPS5799584A - (omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts - Google Patents

(omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts

Info

Publication number
JPS5799584A
JPS5799584A JP17691080A JP17691080A JPS5799584A JP S5799584 A JPS5799584 A JP S5799584A JP 17691080 A JP17691080 A JP 17691080A JP 17691080 A JP17691080 A JP 17691080A JP S5799584 A JPS5799584 A JP S5799584A
Authority
JP
Japan
Prior art keywords
formula
acid addition
compound shown
alkylenedioxybenzenes
aminoalkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP17691080A
Other languages
Japanese (ja)
Other versions
JPH0128029B2 (en
Inventor
Ryoji Kikumoto
Jiichi Fukami
Kenichiro Nakao
Mamoru Kanno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP17691080A priority Critical patent/JPS5799584A/en
Priority to US06/326,417 priority patent/US4684739A/en
Priority to HU813738A priority patent/HU188723B/en
Priority to CA000392241A priority patent/CA1183546A/en
Priority to DK554581A priority patent/DK151256C/en
Priority to DE8181110465T priority patent/DE3165592D1/en
Priority to EP81110465A priority patent/EP0054304B1/en
Publication of JPS5799584A publication Critical patent/JPS5799584A/en
Publication of JPH0128029B2 publication Critical patent/JPH0128029B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI(m is 1W3; R is H or lower alkyl; X is O or methylene) and its acid addition salt.
EXAMPLE: 5-{3-[( 1, 4-benzodioxane-2-ylmethyl )amino]-2-hydroxypropoxy}-1,3- benzodioxole.
USE: A hypotensor. Medicinal effect appears quickly, medicinal action continues prolongably, and acute toxicity is low. A dose per day of effective ingredient is 1W30mg/kg weight generally.
PROCESS: An epoxide shown by the formula II is reacted with an amine shown by the formula III to give a compound shown by the formulaI. The epoxide shown by the formula II is obtained by reacting a compound shown by the formula IV (M is alkali metal) with epichlorohydrin in a nonproton solvent.
COPYRIGHT: (C)1982,JPO&Japio
JP17691080A 1980-12-15 1980-12-15 (omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts Granted JPS5799584A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP17691080A JPS5799584A (en) 1980-12-15 1980-12-15 (omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts
US06/326,417 US4684739A (en) 1980-12-15 1981-12-01 Alkylenedioxybenzene derivatives and acid addition salts thereof
HU813738A HU188723B (en) 1980-12-15 1981-12-11 Process for preparing aljylene-dioxy-benzene derivatives and acid addition salts thereof
CA000392241A CA1183546A (en) 1980-12-15 1981-12-14 Alkylenedioxybenzene derivatives and acid addition salts thereof
DK554581A DK151256C (en) 1980-12-15 1981-12-14 METHOD OF ANALOGY FOR THE PREPARATION OF ALKYLENDIOXYBENZENE DERIVATIVES
DE8181110465T DE3165592D1 (en) 1980-12-15 1981-12-15 Alkylenedioxybenzene derivatives, acid addition salts thereof and a method for their preparation
EP81110465A EP0054304B1 (en) 1980-12-15 1981-12-15 Alkylenedioxybenzene derivatives, acid addition salts thereof and a method for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17691080A JPS5799584A (en) 1980-12-15 1980-12-15 (omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts

Publications (2)

Publication Number Publication Date
JPS5799584A true JPS5799584A (en) 1982-06-21
JPH0128029B2 JPH0128029B2 (en) 1989-05-31

Family

ID=16021886

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17691080A Granted JPS5799584A (en) 1980-12-15 1980-12-15 (omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts

Country Status (1)

Country Link
JP (1) JPS5799584A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS509781A (en) * 1973-06-01 1975-01-31

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS509781A (en) * 1973-06-01 1975-01-31

Also Published As

Publication number Publication date
JPH0128029B2 (en) 1989-05-31

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