JPS5799584A - (omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts - Google Patents
(omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition saltsInfo
- Publication number
- JPS5799584A JPS5799584A JP17691080A JP17691080A JPS5799584A JP S5799584 A JPS5799584 A JP S5799584A JP 17691080 A JP17691080 A JP 17691080A JP 17691080 A JP17691080 A JP 17691080A JP S5799584 A JPS5799584 A JP S5799584A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- acid addition
- compound shown
- alkylenedioxybenzenes
- aminoalkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound shown by the formulaI(m is 1W3; R is H or lower alkyl; X is O or methylene) and its acid addition salt.
EXAMPLE: 5-{3-[( 1, 4-benzodioxane-2-ylmethyl )amino]-2-hydroxypropoxy}-1,3- benzodioxole.
USE: A hypotensor. Medicinal effect appears quickly, medicinal action continues prolongably, and acute toxicity is low. A dose per day of effective ingredient is 1W30mg/kg weight generally.
PROCESS: An epoxide shown by the formula II is reacted with an amine shown by the formula III to give a compound shown by the formulaI. The epoxide shown by the formula II is obtained by reacting a compound shown by the formula IV (M is alkali metal) with epichlorohydrin in a nonproton solvent.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17691080A JPS5799584A (en) | 1980-12-15 | 1980-12-15 | (omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts |
US06/326,417 US4684739A (en) | 1980-12-15 | 1981-12-01 | Alkylenedioxybenzene derivatives and acid addition salts thereof |
HU813738A HU188723B (en) | 1980-12-15 | 1981-12-11 | Process for preparing aljylene-dioxy-benzene derivatives and acid addition salts thereof |
CA000392241A CA1183546A (en) | 1980-12-15 | 1981-12-14 | Alkylenedioxybenzene derivatives and acid addition salts thereof |
DK554581A DK151256C (en) | 1980-12-15 | 1981-12-14 | METHOD OF ANALOGY FOR THE PREPARATION OF ALKYLENDIOXYBENZENE DERIVATIVES |
DE8181110465T DE3165592D1 (en) | 1980-12-15 | 1981-12-15 | Alkylenedioxybenzene derivatives, acid addition salts thereof and a method for their preparation |
EP81110465A EP0054304B1 (en) | 1980-12-15 | 1981-12-15 | Alkylenedioxybenzene derivatives, acid addition salts thereof and a method for their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17691080A JPS5799584A (en) | 1980-12-15 | 1980-12-15 | (omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5799584A true JPS5799584A (en) | 1982-06-21 |
JPH0128029B2 JPH0128029B2 (en) | 1989-05-31 |
Family
ID=16021886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17691080A Granted JPS5799584A (en) | 1980-12-15 | 1980-12-15 | (omega-aminoalkoxy)alkylenedioxybenzenes and their acid addition salts |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5799584A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS509781A (en) * | 1973-06-01 | 1975-01-31 |
-
1980
- 1980-12-15 JP JP17691080A patent/JPS5799584A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS509781A (en) * | 1973-06-01 | 1975-01-31 |
Also Published As
Publication number | Publication date |
---|---|
JPH0128029B2 (en) | 1989-05-31 |
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