JPS5781487A - D-6-methyl 2,8-disubstituted ergoline - Google Patents

D-6-methyl 2,8-disubstituted ergoline

Info

Publication number: JPS5781487A
Authority: JP; Japan
Prior art keywords: ergoline; disubstituted; methyl; disubstituted ergoline
Prior art date: 1972-07-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP56123937A

Other languages

Japanese (ja)

Other versions

JPS5813541B2 (en

Inventor

Aren Kuremensu Jieemuzu

Kaaru Koonfuerudo Edomundo

Jieemuzu Batsuchi Nikorasu

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-07-21

Filing date

1981-08-07

Publication date

1982-05-21

1981-08-07 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1982-05-21 Publication of JPS5781487A publication Critical patent/JPS5781487A/en

1983-03-14 Publication of JPS5813541B2 publication Critical patent/JPS5813541B2/en

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP56123937A 1972-07-21 1981-08-07 D-6-methyl 2,8-disubstituted ergoline Expired JPS5813541B2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US27390272A	1972-07-21	1972-07-21

Publications (2)

Publication Number	Publication Date
JPS5781487A true JPS5781487A (en)	1982-05-21
JPS5813541B2 JPS5813541B2 (en)	1983-03-14

Family

ID=23045910

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
JP8074973A Expired JPS576431B2 (en)	1972-07-21	1973-07-20
JP56123937A Expired JPS5813541B2 (en)	1972-07-21	1981-08-07	D-6-methyl 2,8-disubstituted ergoline

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
JP8074973A Expired JPS576431B2 (en)	1972-07-21	1973-07-20

Country Status (24)

Country	Link
JP (2)	JPS576431B2 (en)
AR (3)	AR206772A1 (en)
AT (1)	AT331425B (en)
BE (1)	BE802531A (en)
BG (3)	BG22400A3 (en)
CA (1)	CA1006159A (en)
CH (5)	CH578564A5 (en)
CS (1)	CS208164B2 (en)
DD (1)	DD107690A5 (en)
DE (2)	DE2335750C3 (en)
DK (1)	DK140986B (en)
ES (5)	ES417078A1 (en)
FR (1)	FR2193606B1 (en)
GB (1)	GB1423065A (en)
HU (1)	HU167274B (en)
IE (1)	IE37936B1 (en)
IL (3)	IL42730A (en)
NL (1)	NL7309969A (en)
PH (1)	PH11229A (en)
RO (2)	RO63792A (en)
SE (3)	SE393111B (en)
SU (3)	SU645581A3 (en)
YU (1)	YU36953B (en)
ZA (1)	ZA734627B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1517973A (en) *	1974-07-19	1978-07-19	Sandoz Ltd	6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
US3968111A (en) *	1974-12-06	1976-07-06	Eli Lilly And Company	8,8-Disubstituted-6-methylergolines and related compounds
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) *	1978-09-08	1983-01-27	Farmitalia Carlo Erba S.P.A.	Ergoline derivatives
EP0160842B1 (en) *	1984-04-09	1994-06-22	Schering Aktiengesellschaft	2-Substituted ergoline derivatives, processes for their preparation, and their use as medicaments
HU196598B (en) *	1986-04-25	1988-12-28	Richter Gedeon Vegyeszet	Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
DE3620293A1 (en) *	1986-06-16	1987-12-17	Schering Ag	1 AND / OR 2 SUBSTITUTED ERGOL DERIVATIVES
JPH0596382U (en) *	1992-05-28	1993-12-27	イビデン株式会社	Door unit

1973
- 1973-01-01 AR AR249167A patent/AR206772A1/en active
- 1973-07-10 GB GB3289073A patent/GB1423065A/en not_active Expired
- 1973-07-10 ZA ZA734627A patent/ZA734627B/en unknown
- 1973-07-12 SE SE7309781A patent/SE393111B/en unknown
- 1973-07-12 IL IL42730A patent/IL42730A/en unknown
- 1973-07-12 IL IL48288A patent/IL48288A/en unknown
- 1973-07-13 DE DE2335750A patent/DE2335750C3/en not_active Expired
- 1973-07-13 DE DE2365974A patent/DE2365974A1/en not_active Withdrawn
- 1973-07-17 NL NL7309969A patent/NL7309969A/xx not_active Application Discontinuation
- 1973-07-17 YU YU1945/73A patent/YU36953B/en unknown
- 1973-07-18 PH PH14835A patent/PH11229A/en unknown
- 1973-07-19 DK DK399873AA patent/DK140986B/en unknown
- 1973-07-19 BE BE1005246A patent/BE802531A/en not_active IP Right Cessation
- 1973-07-19 HU HUEI485A patent/HU167274B/hu unknown
- 1973-07-20 RO RO7300083213A patent/RO63792A/en unknown
- 1973-07-20 RO RO7375548A patent/RO71305A/en unknown
- 1973-07-20 BG BG28443A patent/BG22400A3/xx unknown
- 1973-07-20 DD DD172402A patent/DD107690A5/xx unknown
- 1973-07-20 CS CS735239A patent/CS208164B2/en unknown
- 1973-07-20 AT AT643473A patent/AT331425B/en not_active IP Right Cessation
- 1973-07-20 SU SU731948966A patent/SU645581A3/en active
- 1973-07-20 BG BG24148A patent/BG21410A3/xx unknown
- 1973-07-20 IE IE1238/73A patent/IE37936B1/en unknown
- 1973-07-20 CH CH391376A patent/CH578564A5/xx not_active IP Right Cessation
- 1973-07-20 CH CH391276A patent/CH580626A5/xx not_active IP Right Cessation
- 1973-07-20 CH CH391176A patent/CH578563A5/xx not_active IP Right Cessation
- 1973-07-20 CH CH391076A patent/CH580625A5/xx not_active IP Right Cessation
- 1973-07-20 JP JP8074973A patent/JPS576431B2/ja not_active Expired
- 1973-07-20 BG BG26855A patent/BG21411A3/xx not_active Expired
- 1973-07-20 ES ES417078A patent/ES417078A1/en not_active Expired
- 1973-07-20 CA CA177,021A patent/CA1006159A/en not_active Expired
- 1973-07-20 CH CH1067873A patent/CH581135A5/xx not_active IP Right Cessation
- 1973-07-20 FR FR7326708A patent/FR2193606B1/fr not_active Expired
1974
- 1974-01-01 AR AR252738A patent/AR206887A1/en active
- 1974-12-04 SU SU7402080295A patent/SU584780A3/en active
1975
- 1975-01-14 SU SU7502098198A patent/SU575029A3/en active
- 1975-01-30 AR AR257473A patent/AR210072A1/en active
- 1975-10-13 IL IL48288A patent/IL48288A0/en unknown
- 1975-11-21 ES ES442885A patent/ES442885A1/en not_active Expired
- 1975-11-21 ES ES442886A patent/ES442886A1/en not_active Expired
- 1975-11-21 ES ES442887A patent/ES442887A1/en not_active Expired
1976
- 1976-04-07 ES ES446789A patent/ES446789A1/en not_active Expired
- 1976-10-15 SE SE7611466A patent/SE410459B/en unknown
- 1976-10-15 SE SE7611467A patent/SE410603B/en unknown
1981
- 1981-08-07 JP JP56123937A patent/JPS5813541B2/en not_active Expired

Also Published As

Publication number	Publication date
IL42730A (en)	1976-06-30
PH11229A (en)	1977-10-28
ES446789A1 (en)	1977-06-01
SU645581A3 (en)	1979-01-30
AT331425B (en)	1976-08-25
IL42730A0 (en)	1973-10-25
CH581135A5 (en)	1976-10-29
SE410459B (en)	1979-10-15
SE7611466L (en)	1976-10-15
DK140986C (en)	1980-07-21
BG21410A3 (en)	1976-05-20
YU194573A (en)	1982-06-18
AR206772A1 (en)	1976-08-23
DE2335750C3 (en)	1978-10-19
CH578563A5 (en)	1976-08-13
RO71305A (en)	1982-03-24
IE37936L (en)	1974-01-21
CA1006159A (en)	1977-03-01
ATA643473A (en)	1975-11-15
CH578564A5 (en)	1976-08-13
RO63792A (en)	1978-12-15
ES442885A1 (en)	1977-04-16
FR2193606A1 (en)	1974-02-22
AR210072A1 (en)	1977-06-30
IL48288A0 (en)	1975-12-31
HU167274B (en)	1975-09-27
ZA734627B (en)	1974-06-26
IE37936B1 (en)	1977-11-23
JPS4985099A (en)	1974-08-15
BG21411A3 (en)	1976-05-20
DE2335750A1 (en)	1974-02-14
ES417078A1 (en)	1976-05-01
DE2365974A1 (en)	1977-03-24
FR2193606B1 (en)	1977-07-15
DK140986B (en)	1979-12-17
IL48288A (en)	1976-06-30
DE2335750B2 (en)	1978-02-23
BE802531A (en)	1974-01-21
SU575029A3 (en)	1977-09-30
ES442886A1 (en)	1977-04-16
ES442887A1 (en)	1977-05-16
CH580626A5 (en)	1976-10-15
BG22400A3 (en)	1977-02-20
CH580625A5 (en)	1976-10-15
CS208164B2 (en)	1981-08-31
SU584780A3 (en)	1977-12-15
GB1423065A (en)	1976-01-28
SE410603B (en)	1979-10-22
DD107690A5 (en)	1974-08-12
NL7309969A (en)	1974-01-23
YU36953B (en)	1984-08-31
SE393111B (en)	1977-05-02
SE7611467L (en)	1976-10-15
AU5792673A (en)	1975-01-16
JPS576431B2 (en)	1982-02-04
JPS5813541B2 (en)	1983-03-14
AR206887A1 (en)	1976-08-31

Publication	Publication Date	Title
IL43795A (en)	1978-03-10	3-aminoalkylamino-1-phenoxy-2-propanol derivatives
HK27979A (en)	1979-05-11	Substituted 16,17,18,19,20-pentanorprostaglandins
KE2670A (en)	1976-11-12	1,2,3,-thiadiazole derivatives
IL41060A0 (en)	1973-02-28	Alpha-aryl-4-substituted piperidinoalkanol derivatives
CY992A (en)	1979-08-02	Benzocycloheptathiophene derivatives
JPS5781487A (en)	1982-05-21	D-6-methyl 2,8-disubstituted ergoline
GB1402219A (en)	1975-08-06	Berbine derivatives
GB1406961A (en)	1975-09-17	2,4,7-trioxopteridine derivatives
IL42943A (en)	1978-04-30	16-methyl-prednisolone derivatives
IL43280A0 (en)	1973-11-28	Amidinourea derivatives
IL41789A0 (en)	1973-05-31	Diphenylalkyllactamimide derivatives
PH10465A (en)	1977-04-25	Debenzazecine derivatives
JPS5745162A (en)	1982-03-13	Substituted 1,2,4,5-tetrahydro-3h,3-benzoazepines
GB1402046A (en)	1975-08-06	11,12-epoxyerythromycins
HK15179A (en)	1979-03-30	2,6-diaminoneburlarine derivatives
IL43666A0 (en)	1974-03-14	Substituted 9,10-dihydro-anthracenes
AU5916873A (en)	1975-02-13	Cyclohexanepentol derivative
GB1404277A (en)	1975-08-28	16,17-seco-d-homosteroids
PH12035A (en)	1978-10-16	Oxaprostaglandin intermediate
AU5423773A (en)	1974-10-10	Alpha-pyrone derivatives
PH10653A (en)	1977-07-27	Indolylimidoylquinoline derivatives
PH10601A (en)	1977-07-15	Diaza-oxa-bicyclodecane derivatives
HK380A (en)	1980-01-11	Benzoisoindoline derivatives
AU5872373A (en)	1975-02-06	Isoxolidine derivatives
AU481948B2 (en)	1975-01-16	D-6-methyl 2, 8-disubstituted ergolines