DK140986B - Analogous process for the preparation of 8-substituted D-2-halogen-6-methyl-ergolines and their salts. - Google Patents

Analogous process for the preparation of 8-substituted D-2-halogen-6-methyl-ergolines and their salts.

Info

Publication number
DK140986B
DK140986B DK399873AA DK399873A DK140986B DK 140986 B DK140986 B DK 140986B DK 399873A A DK399873A A DK 399873AA DK 399873 A DK399873 A DK 399873A DK 140986 B DK140986 B DK 140986B
Authority
DK
Denmark
Prior art keywords
ergolines
halogen
salts
substituted
methyl
Prior art date
Application number
DK399873AA
Other languages
Danish (da)
Other versions
DK140986C (en
Inventor
James Allen Clemens
Edmund Carl Kornfeld
Nicholas James Bach
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to DK71775A priority Critical patent/DK139154B/en
Priority to DK71875A priority patent/DK71875A/da
Publication of DK140986B publication Critical patent/DK140986B/en
Application granted granted Critical
Publication of DK140986C publication Critical patent/DK140986C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK399873AA 1972-07-21 1973-07-19 Analogous process for the preparation of 8-substituted D-2-halogen-6-methyl-ergolines and their salts. DK140986B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK71775A DK139154B (en) 1972-07-21 1975-02-25 Ergoline derivative for use as an intermediate in the preparation of 2,8-substituted 6-methyl-ergolines.
DK71875A DK71875A (en) 1972-07-21 1975-02-25

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27390272A 1972-07-21 1972-07-21

Publications (2)

Publication Number Publication Date
DK140986B true DK140986B (en) 1979-12-17
DK140986C DK140986C (en) 1980-07-21

Family

ID=23045910

Family Applications (1)

Application Number Title Priority Date Filing Date
DK399873AA DK140986B (en) 1972-07-21 1973-07-19 Analogous process for the preparation of 8-substituted D-2-halogen-6-methyl-ergolines and their salts.

Country Status (24)

Country Link
JP (2) JPS576431B2 (en)
AR (3) AR206772A1 (en)
AT (1) AT331425B (en)
BE (1) BE802531A (en)
BG (3) BG22400A3 (en)
CA (1) CA1006159A (en)
CH (5) CH578564A5 (en)
CS (1) CS208164B2 (en)
DD (1) DD107690A5 (en)
DE (2) DE2335750C3 (en)
DK (1) DK140986B (en)
ES (5) ES417078A1 (en)
FR (1) FR2193606B1 (en)
GB (1) GB1423065A (en)
HU (1) HU167274B (en)
IE (1) IE37936B1 (en)
IL (3) IL48288A (en)
NL (1) NL7309969A (en)
PH (1) PH11229A (en)
RO (2) RO63792A (en)
SE (3) SE393111B (en)
SU (3) SU645581A3 (en)
YU (1) YU36953B (en)
ZA (1) ZA734627B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517973A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
ATE107647T1 (en) * 1984-04-09 1994-07-15 Schering Ag 2-SUBSTITUTED ERGOLINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS.
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
DE3620293A1 (en) * 1986-06-16 1987-12-17 Schering Ag 1 AND / OR 2 SUBSTITUTED ERGOL DERIVATIVES
JPH0596382U (en) * 1992-05-28 1993-12-27 イビデン株式会社 Door unit

Also Published As

Publication number Publication date
RO63792A (en) 1978-12-15
SU645581A3 (en) 1979-01-30
SE7611467L (en) 1976-10-15
CH578563A5 (en) 1976-08-13
RO71305A (en) 1982-03-24
NL7309969A (en) 1974-01-23
IE37936B1 (en) 1977-11-23
IE37936L (en) 1974-01-21
CH581135A5 (en) 1976-10-29
SE410459B (en) 1979-10-15
PH11229A (en) 1977-10-28
BG22400A3 (en) 1977-02-20
ES446789A1 (en) 1977-06-01
AU5792673A (en) 1975-01-16
SU584780A3 (en) 1977-12-15
ES442887A1 (en) 1977-05-16
HU167274B (en) 1975-09-27
ES442885A1 (en) 1977-04-16
SE7611466L (en) 1976-10-15
IL48288A (en) 1976-06-30
DK140986C (en) 1980-07-21
FR2193606A1 (en) 1974-02-22
JPS5781487A (en) 1982-05-21
BG21410A3 (en) 1976-05-20
DE2335750A1 (en) 1974-02-14
CA1006159A (en) 1977-03-01
CH580626A5 (en) 1976-10-15
SE393111B (en) 1977-05-02
BE802531A (en) 1974-01-21
CS208164B2 (en) 1981-08-31
ATA643473A (en) 1975-11-15
JPS5813541B2 (en) 1983-03-14
GB1423065A (en) 1976-01-28
ES417078A1 (en) 1976-05-01
CH578564A5 (en) 1976-08-13
SU575029A3 (en) 1977-09-30
AT331425B (en) 1976-08-25
DE2365974A1 (en) 1977-03-24
FR2193606B1 (en) 1977-07-15
AR206887A1 (en) 1976-08-31
JPS576431B2 (en) 1982-02-04
ES442886A1 (en) 1977-04-16
ZA734627B (en) 1974-06-26
JPS4985099A (en) 1974-08-15
CH580625A5 (en) 1976-10-15
BG21411A3 (en) 1976-05-20
DE2335750C3 (en) 1978-10-19
DD107690A5 (en) 1974-08-12
IL42730A0 (en) 1973-10-25
YU36953B (en) 1984-08-31
YU194573A (en) 1982-06-18
AR206772A1 (en) 1976-08-23
SE410603B (en) 1979-10-22
AR210072A1 (en) 1977-06-30
IL42730A (en) 1976-06-30
IL48288A0 (en) 1975-12-31
DE2335750B2 (en) 1978-02-23

Similar Documents

Publication Publication Date Title
DK137329B (en) Analogous process for the preparation of 2-carbalkoxyaminobenzimidazole derivatives.
DK134607B (en) Process for the preparation of rapamycin.
DK131868B (en) Analogous process for the preparation of the tri-p-toluenesulfonate of S-adenosyl-L-methionine.
DK135505B (en) Analogous process for the preparation of morpholine derivatives.
DK138020B (en) Analogous process for the preparation of pyrazolodiazepine compounds or salts thereof.
DK134599B (en) Analogous process for the preparation of pyrroleacetic acid derivatives and their salts.
DK140986B (en) Analogous process for the preparation of 8-substituted D-2-halogen-6-methyl-ergolines and their salts.
DK134604B (en) Process for the preparation of indenyl-3-acetoglucuronides.
DK138230B (en) Analogous process for the preparation of vincanol salts.
DK138796B (en) Analogous process for the preparation of 2-carboxypyrazine-4-oxide derivatives.
DK131864B (en) Process for the preparation of pregnan-21-acid derivatives.
DK140669B (en) Process for the preparation of alpha-aminobenzylpenicillins and their salts.
DK132233B (en) Process for the preparation of antibiotic A-2315.
DK138645B (en) Analogous process for the preparation of sulfamoylphenyl-imidazolidines.
DK131575B (en) Analogous process for the preparation of 2beta-hydroxy-3alpha-aminosteroids.
DK135122B (en) Analogous process for the preparation of 4-aryl-5-aminoalkyl-4-oxazolin-2-one derivatives.
DK138745B (en) Process for the preparation of cephalexin or salts thereof.
DK133667B (en) Process for the preparation of 5-cyclohexyl-6-haloindane-1-carboxylic acid derivatives.
DK132430B (en) Process for the preparation of quinazolinone derivatives.
DK136361B (en) Process for the preparation of quinoline derivatives.
DK135166B (en) Analogous process for the preparation of 2-methyl-5-nitro-imidazoles.
DK129657B (en) Analogous process for the preparation of 3-methylpyrazole-5-carboxamides.
DK134183B (en) Process for the preparation of cellulose-enzyme complexes.
DK139677B (en) Process for the preparation of 7-benzoylindolin-2-ones.
DK132410B (en) Analogous process for the preparation of 2-amino-4H-pyranes.