JPS5618989A - Imidazole derivative and its preparation - Google Patents
Imidazole derivative and its preparationInfo
- Publication number
- JPS5618989A JPS5618989A JP9518179A JP9518179A JPS5618989A JP S5618989 A JPS5618989 A JP S5618989A JP 9518179 A JP9518179 A JP 9518179A JP 9518179 A JP9518179 A JP 9518179A JP S5618989 A JPS5618989 A JP S5618989A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- compound
- imidazole derivative
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An imidazole derivative of formula I (R1 is H, halogen, 1W6C alkyl, etc.; R2 is H or 1W6C alkyl; R3 is H, 2W6C alkyl, aryl, etc.; R4 is H, 1W6C alkyl or aryl; provided that all of R2WR4 are not H at the same time), and its acid addition salt.
EXAMPLE: 3,4-Dihydro-4-methyl-2H-( 1,3 )-thiazino-[ 3,2-a ]-benzimidazole.hydrochloride.
USE: Peripheral vessel dilator, hypotensor, and coronary vessel dilator, capable of dilating coronary vessel without increasing the oxygen consumption of heart. Effective to remedy for ischemic cardiopathy.
PROCESS: The compound of formula I can be prepared, e.g. by reacting a compound of formula II with a compound of formula III (X, Y are halogen) in an inert solvent in the presence of a base such as NaOH.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54095181A JPS6038396B2 (en) | 1979-07-26 | 1979-07-26 | Imidazole derivatives and their production method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54095181A JPS6038396B2 (en) | 1979-07-26 | 1979-07-26 | Imidazole derivatives and their production method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5618989A true JPS5618989A (en) | 1981-02-23 |
JPS6038396B2 JPS6038396B2 (en) | 1985-08-31 |
Family
ID=14130572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP54095181A Expired JPS6038396B2 (en) | 1979-07-26 | 1979-07-26 | Imidazole derivatives and their production method |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6038396B2 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5818741A (en) * | 1981-07-24 | 1983-02-03 | Hitachi Ltd | Terminal device |
EP0129409A2 (en) * | 1983-06-18 | 1984-12-27 | JOHN WYETH & BROTHER LIMITED | Thiazolo - and thiazinobenzimidazoles |
JPS60103337A (en) * | 1983-11-10 | 1985-06-07 | Konishiroku Photo Ind Co Ltd | Printing device for additional information |
JPS6345685A (en) * | 1986-08-13 | 1988-02-26 | Fujitsu Ltd | Image processing control system |
US4873237A (en) * | 1983-06-18 | 1989-10-10 | John Wyeth & Brother Limited | 2,3-dihydro- thiazolo- and thiazino- benzimidazoles as atni-hyper secretion agents |
-
1979
- 1979-07-26 JP JP54095181A patent/JPS6038396B2/en not_active Expired
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5818741A (en) * | 1981-07-24 | 1983-02-03 | Hitachi Ltd | Terminal device |
JPS6321927B2 (en) * | 1981-07-24 | 1988-05-10 | Hitachi Ltd | |
EP0129409A2 (en) * | 1983-06-18 | 1984-12-27 | JOHN WYETH & BROTHER LIMITED | Thiazolo - and thiazinobenzimidazoles |
JPS6013794A (en) * | 1983-06-18 | 1985-01-24 | ジヨン・ワイス・アンド・ブラザ−・リミテツド | Thiazolo and thiazinobenzoimidazole |
US4873237A (en) * | 1983-06-18 | 1989-10-10 | John Wyeth & Brother Limited | 2,3-dihydro- thiazolo- and thiazino- benzimidazoles as atni-hyper secretion agents |
JPS60103337A (en) * | 1983-11-10 | 1985-06-07 | Konishiroku Photo Ind Co Ltd | Printing device for additional information |
JPS6345685A (en) * | 1986-08-13 | 1988-02-26 | Fujitsu Ltd | Image processing control system |
Also Published As
Publication number | Publication date |
---|---|
JPS6038396B2 (en) | 1985-08-31 |
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