JPS5618989A - Imidazole derivative and its preparation - Google Patents

Imidazole derivative and its preparation

Info

Publication number
JPS5618989A
JPS5618989A JP9518179A JP9518179A JPS5618989A JP S5618989 A JPS5618989 A JP S5618989A JP 9518179 A JP9518179 A JP 9518179A JP 9518179 A JP9518179 A JP 9518179A JP S5618989 A JPS5618989 A JP S5618989A
Authority
JP
Japan
Prior art keywords
alkyl
formula
compound
imidazole derivative
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9518179A
Other languages
Japanese (ja)
Other versions
JPS6038396B2 (en
Inventor
Hiromichi Eto
Tadayuki Koda
Yoichiro Ogawa
Susumu Sato
Toshiaki Nakajima
Yoshichika Odaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SSP Co Ltd
Original Assignee
SSP Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SSP Co Ltd filed Critical SSP Co Ltd
Priority to JP54095181A priority Critical patent/JPS6038396B2/en
Publication of JPS5618989A publication Critical patent/JPS5618989A/en
Publication of JPS6038396B2 publication Critical patent/JPS6038396B2/en
Expired legal-status Critical Current

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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:An imidazole derivative of formula I (R1 is H, halogen, 1W6C alkyl, etc.; R2 is H or 1W6C alkyl; R3 is H, 2W6C alkyl, aryl, etc.; R4 is H, 1W6C alkyl or aryl; provided that all of R2WR4 are not H at the same time), and its acid addition salt.
EXAMPLE: 3,4-Dihydro-4-methyl-2H-( 1,3 )-thiazino-[ 3,2-a ]-benzimidazole.hydrochloride.
USE: Peripheral vessel dilator, hypotensor, and coronary vessel dilator, capable of dilating coronary vessel without increasing the oxygen consumption of heart. Effective to remedy for ischemic cardiopathy.
PROCESS: The compound of formula I can be prepared, e.g. by reacting a compound of formula II with a compound of formula III (X, Y are halogen) in an inert solvent in the presence of a base such as NaOH.
COPYRIGHT: (C)1981,JPO&Japio
JP54095181A 1979-07-26 1979-07-26 Imidazole derivatives and their production method Expired JPS6038396B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP54095181A JPS6038396B2 (en) 1979-07-26 1979-07-26 Imidazole derivatives and their production method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54095181A JPS6038396B2 (en) 1979-07-26 1979-07-26 Imidazole derivatives and their production method

Publications (2)

Publication Number Publication Date
JPS5618989A true JPS5618989A (en) 1981-02-23
JPS6038396B2 JPS6038396B2 (en) 1985-08-31

Family

ID=14130572

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54095181A Expired JPS6038396B2 (en) 1979-07-26 1979-07-26 Imidazole derivatives and their production method

Country Status (1)

Country Link
JP (1) JPS6038396B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5818741A (en) * 1981-07-24 1983-02-03 Hitachi Ltd Terminal device
EP0129409A2 (en) * 1983-06-18 1984-12-27 JOHN WYETH & BROTHER LIMITED Thiazolo - and thiazinobenzimidazoles
JPS60103337A (en) * 1983-11-10 1985-06-07 Konishiroku Photo Ind Co Ltd Printing device for additional information
JPS6345685A (en) * 1986-08-13 1988-02-26 Fujitsu Ltd Image processing control system
US4873237A (en) * 1983-06-18 1989-10-10 John Wyeth & Brother Limited 2,3-dihydro- thiazolo- and thiazino- benzimidazoles as atni-hyper secretion agents

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5818741A (en) * 1981-07-24 1983-02-03 Hitachi Ltd Terminal device
JPS6321927B2 (en) * 1981-07-24 1988-05-10 Hitachi Ltd
EP0129409A2 (en) * 1983-06-18 1984-12-27 JOHN WYETH & BROTHER LIMITED Thiazolo - and thiazinobenzimidazoles
JPS6013794A (en) * 1983-06-18 1985-01-24 ジヨン・ワイス・アンド・ブラザ−・リミテツド Thiazolo and thiazinobenzoimidazole
US4873237A (en) * 1983-06-18 1989-10-10 John Wyeth & Brother Limited 2,3-dihydro- thiazolo- and thiazino- benzimidazoles as atni-hyper secretion agents
JPS60103337A (en) * 1983-11-10 1985-06-07 Konishiroku Photo Ind Co Ltd Printing device for additional information
JPS6345685A (en) * 1986-08-13 1988-02-26 Fujitsu Ltd Image processing control system

Also Published As

Publication number Publication date
JPS6038396B2 (en) 1985-08-31

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