JPS5283393A - Synthesis of novel penicillin derivatives - Google Patents

Synthesis of novel penicillin derivatives

Info

Publication number
JPS5283393A
JPS5283393A JP15787475A JP15787475A JPS5283393A JP S5283393 A JPS5283393 A JP S5283393A JP 15787475 A JP15787475 A JP 15787475A JP 15787475 A JP15787475 A JP 15787475A JP S5283393 A JPS5283393 A JP S5283393A
Authority
JP
Japan
Prior art keywords
synthesis
penicillin derivatives
novel penicillin
novel
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15787475A
Other languages
Japanese (ja)
Other versions
JPS5653302B2 (en
Inventor
Mitsutaka Kawazu
Kokichi Azuma
Masahiko Seto
Riichi Miyagishima
Totaro Yamaguchi
Satoshi Oshima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP15787475A priority Critical patent/JPS5283393A/en
Priority to US05/711,858 priority patent/US4053609A/en
Priority to DE2638067A priority patent/DE2638067C2/en
Priority to FI762576A priority patent/FI63413C/en
Priority to SE7609909A priority patent/SE430337B/en
Priority to BE170545A priority patent/BE846094A/en
Priority to FR7627393A priority patent/FR2323384A1/en
Priority to CA260,920A priority patent/CA1081211A/en
Priority to DK411076A priority patent/DK144301C/en
Priority to NLAANVRAGE7610151,A priority patent/NL176677C/en
Priority to AU17697/76A priority patent/AU493313B2/en
Priority to MX765180U priority patent/MX4004E/en
Priority to GB5045476A priority patent/GB1533414A/en
Priority to ES454104A priority patent/ES454104A1/en
Priority to HU76TA1421A priority patent/HU173398B/en
Priority to CS768400A priority patent/CS192469B2/en
Priority to AT942476A priority patent/AT347584B/en
Priority to PH19281A priority patent/PH16100A/en
Priority to PL1976194671A priority patent/PL102737B1/en
Priority to SU762431353A priority patent/SU622407A3/en
Priority to AR266007A priority patent/AR219063A1/en
Priority to CH1635976A priority patent/CH605982A5/en
Publication of JPS5283393A publication Critical patent/JPS5283393A/en
Publication of JPS5653302B2 publication Critical patent/JPS5653302B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom

Abstract

PURPOSE: Penicillin derivatives of formula I (R1 is H, 1-5 C alkyl); for example, 6-D-2-(D-2-amini-3-carbamoylpropionamido)-2-p-hydroxyphenylacetamido) penicillanic acid K salt.
COPYRIGHT: (C)1977,JPO&Japio
JP15787475A 1975-09-12 1975-12-27 Synthesis of novel penicillin derivatives Granted JPS5283393A (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
JP15787475A JPS5283393A (en) 1975-12-27 1975-12-27 Synthesis of novel penicillin derivatives
US05/711,858 US4053609A (en) 1975-09-12 1976-08-05 Penicillins and processes for preparing the same
DE2638067A DE2638067C2 (en) 1975-09-12 1976-08-24 Penicillins and processes for their manufacture
FI762576A FI63413C (en) 1975-09-12 1976-09-08 FOERFARANDE FOER FRAMSTAELLNING AV ANTIMIKROBA 6- (D-2-AMINO-2-PHENYLACETAMIDO) PENICILLANSYRADERIVAT
SE7609909A SE430337B (en) 1975-09-12 1976-09-08 PROCEDURE FOR PREPARING 6- (D-2-AMINO-2-PHENYL-ACETAMIDO) -PENICILLANIC ACID DERIVATIVES
BE170545A BE846094A (en) 1975-09-12 1976-09-10 NEW PENICILLINS AND THEIR PREPARATION METHODS
FR7627393A FR2323384A1 (en) 1975-09-12 1976-09-10 NEW PENICILLINS AND METHODS FOR THEIR PREPARATION
CA260,920A CA1081211A (en) 1975-09-12 1976-09-10 Penicillins and processes for preparing the same
DK411076A DK144301C (en) 1975-09-12 1976-09-10 ANALOGY PROCEDURE FOR PENICILLIN OR SALT PREPARATION
NLAANVRAGE7610151,A NL176677C (en) 1975-09-12 1976-09-13 METHOD FOR PREPARING OR MANUFACTURING A MEDICINAL PRODUCT WITH ANTIBACTERIAL ACTION AND METHOD FOR PREPARING AN ALPHA-AMINOBENZYL-PENICILLIN DERIVATIVE FURGED BY AN AMINOIC ACID
AU17697/76A AU493313B2 (en) 1976-09-13 6-(d-2-acylamido-2-phenylacetamido) penicillanic acids and their preparation
MX765180U MX4004E (en) 1975-12-27 1976-11-30 PROCEDURE FOR PREPARING ACID 6- (D-2-ACILAMIDO-2-FENILACETAMIDO) PENICILANICO
GB5045476A GB1533414A (en) 1975-09-12 1976-12-03 Process for preparing penicillins
ES454104A ES454104A1 (en) 1975-12-27 1976-12-09 Synthesis of novel penicillin derivatives
HU76TA1421A HU173398B (en) 1975-12-27 1976-12-13 Process for preparing 6-/d-2-acylamino-2-phenylacetamino/-penam-3-carboxylic acid derivatives
CS768400A CS192469B2 (en) 1975-12-27 1976-12-20 Process for preparing 6-/d-2-acylamido-2-phenylacetamido/penicilanic acid
AT942476A AT347584B (en) 1975-12-27 1976-12-20 PROCESS FOR THE PRODUCTION OF NEW PENICILLINS AND THEIR PHARMACEUTICAL SALT
PH19281A PH16100A (en) 1975-12-27 1976-12-22 Process for preparing new penicillin
PL1976194671A PL102737B1 (en) 1975-12-27 1976-12-23 METHOD OF MAKING 6- / D-2-ACYLOAMIDO-2-PHENYLACETAMIDO / PENICYLATIC ACID
SU762431353A SU622407A3 (en) 1975-12-27 1976-12-24 Method of producing derivatives of 61-(d-2-acylamido-2-phenylacetamido)-penicillanic acids or their salts
AR266007A AR219063A1 (en) 1975-12-27 1976-12-27 PROCEDURE FOR THE PREPARATION OF COMPOUNDS OF ACID 6- (D-2-ACILAMIDO-2-FENILACETAMIDO) PENICILANICO
CH1635976A CH605982A5 (en) 1975-12-27 1976-12-27 (2)-Acylamino-(2)-phenylacetamido penicillins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15787475A JPS5283393A (en) 1975-12-27 1975-12-27 Synthesis of novel penicillin derivatives

Publications (2)

Publication Number Publication Date
JPS5283393A true JPS5283393A (en) 1977-07-12
JPS5653302B2 JPS5653302B2 (en) 1981-12-17

Family

ID=15659284

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15787475A Granted JPS5283393A (en) 1975-09-12 1975-12-27 Synthesis of novel penicillin derivatives

Country Status (11)

Country Link
JP (1) JPS5283393A (en)
AR (1) AR219063A1 (en)
AT (1) AT347584B (en)
CH (1) CH605982A5 (en)
CS (1) CS192469B2 (en)
ES (1) ES454104A1 (en)
HU (1) HU173398B (en)
MX (1) MX4004E (en)
PH (1) PH16100A (en)
PL (1) PL102737B1 (en)
SU (1) SU622407A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5640686A (en) * 1979-09-11 1981-04-16 Tanabe Seiyaku Co Ltd Purification of penicillin derivative

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5640686A (en) * 1979-09-11 1981-04-16 Tanabe Seiyaku Co Ltd Purification of penicillin derivative
JPS6210511B2 (en) * 1979-09-11 1987-03-06 Tanabe Seiyaku Co

Also Published As

Publication number Publication date
JPS5653302B2 (en) 1981-12-17
SU622407A3 (en) 1978-08-30
AR219063A1 (en) 1980-07-31
PL102737B1 (en) 1979-04-30
HU173398B (en) 1979-05-28
AT347584B (en) 1979-01-10
ES454104A1 (en) 1978-03-01
CH605982A5 (en) 1978-10-13
ATA942476A (en) 1978-05-15
PH16100A (en) 1983-06-24
MX4004E (en) 1981-10-29
CS192469B2 (en) 1979-08-31

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