JPS5793972A - Preparation of piperazine derivative - Google Patents
Preparation of piperazine derivativeInfo
- Publication number
- JPS5793972A JPS5793972A JP56116541A JP11654181A JPS5793972A JP S5793972 A JPS5793972 A JP S5793972A JP 56116541 A JP56116541 A JP 56116541A JP 11654181 A JP11654181 A JP 11654181A JP S5793972 A JPS5793972 A JP S5793972A
- Authority
- JP
- Japan
- Prior art keywords
- isopropenyl
- trialkoxybenzylpiperazine
- preparation
- piperazine derivative
- coronary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The N-substituted trialkoxybenzylpiperazine derivtive of formulaI(R is CH3 or C2H5; Z is isopropenyl).
EXAMPLE: N-Isopropenyl-N'-2,3,4-trimethoxybenzylpiperazine.
USE: Remedy for iscemic cardiopathy. It has various pharmacological activities to coronary circulatory system such as coronary vessel dilating action, cardiac motion suppressing action, etc.
PROCESS: The compound of formulaIcan be prepared in high yield, by reacting the N-trialkoxybenzylpiperazine of formula II with an isopropenyl halide in an inert solvent such as DMF, etc. at room temp. W100°C for 0.5W6hr, if necessary in the presence of a proper acid acceptor.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56116541A JPS5793972A (en) | 1981-07-24 | 1981-07-24 | Preparation of piperazine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56116541A JPS5793972A (en) | 1981-07-24 | 1981-07-24 | Preparation of piperazine derivative |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2744277A Division JPS53112886A (en) | 1976-04-09 | 1977-03-12 | Production of n-substituted trialkoxybenzylpiperazine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5793972A true JPS5793972A (en) | 1982-06-11 |
Family
ID=14689666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56116541A Pending JPS5793972A (en) | 1981-07-24 | 1981-07-24 | Preparation of piperazine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5793972A (en) |
-
1981
- 1981-07-24 JP JP56116541A patent/JPS5793972A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS56103168A (en) | Thiazole derivative, its preparation, and antihistaminic agent containing the same | |
JPS5793972A (en) | Preparation of piperazine derivative | |
JPS5793971A (en) | Preparation of piperazine derivative | |
JPS5793975A (en) | Preparation of piperazine derivative | |
JPS5618989A (en) | Imidazole derivative and its preparation | |
ES8307236A1 (en) | Process for the preparation of a furan derivative. | |
JPS57131777A (en) | Preparation of piperazine derivative | |
JPS527994A (en) | Process for preparing novel pyrimido (4,5-d) pyrimidine derivatives | |
JPS5655383A (en) | Amizine derivative and its preparation | |
JPS5793967A (en) | Preparation of piperazine derivative | |
JPS51113882A (en) | Method for preparing 1-(alpha -alkoxyalkyl)-uracil derivatives | |
JPS5416466A (en) | Novel 3-hydroxypyrrolldine-3-carboxylic derivative | |
JPS5671081A (en) | Thiazolinedicarboxylic acid derivative | |
JPS55136281A (en) | Xanthine derivative | |
JPS5711975A (en) | Aminophenyltetrazole derivative and salt thereof | |
JPS5547651A (en) | Production of sulfoxyimine | |
JPS54106481A (en) | Novel 2,3-dioxopiperazine derivative and its preparation | |
JPS5673077A (en) | Preparation of 2-oxazolidone-3,5-disubstitution compound | |
JPS5553299A (en) | N2-substituted-phenyl-2,6-diaminonebularine | |
JPS5239672A (en) | Process for preparing indole-2-allyl-3- thioeter compounds | |
JPS5387370A (en) | Preparation of penicillamine derivative | |
JPS5419985A (en) | Production of hydroxycarbostyril derivative | |
JPS5553292A (en) | Xanthine derivative | |
JPS525767A (en) | Preparation of novel organic compounds | |
JPS51128961A (en) | Process for preparing 8-azaprostanoic acid derivatives |