JPH0569113B2 - - Google Patents

Info

Publication number: JPH0569113B2
Authority: JP; Japan
Prior art keywords: tumor; platinum; aminomethylaziridine; water; dichloro
Prior art date: 1985-01-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP1146186A

Other languages

English (en)

Japanese (ja)

Other versions

JPS61267595A (ja

Inventor

Kazumi Morikawa

Narimitsu Pponda

Koichi Endo

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Chugai Pharmaceutical Co Ltd

Original Assignee

Chugai Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-22

Filing date

1986-01-22

Publication date

1993-09-30

1986-01-22 Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd

1986-11-27 Publication of JPS61267595A publication Critical patent/JPS61267595A/ja

1993-09-30 Publication of JPH0569113B2 publication Critical patent/JPH0569113B2/ja

Status Granted legal-status Critical Current

Links

BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 17
229910052697 platinum Inorganic materials 0.000 claims description 8
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
206010028980 Neoplasm Diseases 0.000 description 6
230000000259 anti-tumor effect Effects 0.000 description 6
AEXCVBXGIHNPIK-UHFFFAOYSA-N aziridin-2-ylmethanamine Chemical compound NCC1CN1 AEXCVBXGIHNPIK-UHFFFAOYSA-N 0.000 description 6
WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 4
DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 description 4
150000001875 compounds Chemical class 0.000 description 4
239000003814 drug Substances 0.000 description 3
238000001914 filtration Methods 0.000 description 3
201000009030 Carcinoma Diseases 0.000 description 2
241000699670 Mus sp. Species 0.000 description 2
239000002246 antineoplastic agent Substances 0.000 description 2
229960004316 cisplatin Drugs 0.000 description 2
210000001072 colon Anatomy 0.000 description 2
238000000354 decomposition reaction Methods 0.000 description 2
229940079593 drug Drugs 0.000 description 2
230000000694 effects Effects 0.000 description 2
231100000053 low toxicity Toxicity 0.000 description 2
238000002844 melting Methods 0.000 description 2
230000008018 melting Effects 0.000 description 2
150000003057 platinum Chemical class 0.000 description 2
235000011164 potassium chloride Nutrition 0.000 description 2
239000001103 potassium chloride Substances 0.000 description 2
239000007787 solid Substances 0.000 description 2
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 1
241000699666 Mus <mouse, genus> Species 0.000 description 1
206010029155 Nephropathy toxic Diseases 0.000 description 1
238000001816 cooling Methods 0.000 description 1
238000001647 drug administration Methods 0.000 description 1
238000000921 elemental analysis Methods 0.000 description 1
230000009036 growth inhibition Effects 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
238000002513 implantation Methods 0.000 description 1
230000005917 in vivo anti-tumor Effects 0.000 description 1
230000007694 nephrotoxicity Effects 0.000 description 1
231100000417 nephrotoxicity Toxicity 0.000 description 1
238000001228 spectrum Methods 0.000 description 1
238000003756 stirring Methods 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1
230000001988 toxicity Effects 0.000 description 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP61011461A 1985-01-22 1986-01-22 新規白金錯体 Granted JPS61267595A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP838385		1985-01-22
JP60-8383		1985-01-22

Publications (2)

Publication Number	Publication Date
JPS61267595A JPS61267595A (ja)	1986-11-27
JPH0569113B2 true JPH0569113B2 (ko)	1993-09-30

Family

ID=11691693

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP61011461A Granted JPS61267595A (ja)	1985-01-22	1986-01-22	新規白金錯体

Country Status (1)

Country	Link
JP (1)	JPS61267595A (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH093711A (ja) *	1995-06-16	1997-01-07	Nagai Emiko	長袖部肩部襟部開閉衣類

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6310724A (ja) *	1986-03-11	1988-01-18	Chugai Pharmaceut Co Ltd	新規白金錯体を有効成分として含有する制癌剤
JPS6310725A (ja) *	1986-03-11	1988-01-18	Chugai Pharmaceut Co Ltd	新規白金錯体化合物を有効成分として含有する制癌剤

1986
- 1986-01-22 JP JP61011461A patent/JPS61267595A/ja active Granted

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH093711A (ja) *	1995-06-16	1997-01-07	Nagai Emiko	長袖部肩部襟部開閉衣類

Also Published As

Publication number	Publication date
JPS61267595A (ja)	1986-11-27

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