JP6672441B2 - 新規なバチルス・ベレゼンシスcjbv及びそれを含む抗菌組成物 - Google Patents
新規なバチルス・ベレゼンシスcjbv及びそれを含む抗菌組成物 Download PDFInfo
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Description
(1)菌株の分離及び選別
抗菌活性のある菌株を選別するために、在来式味噌玉麹から分離したバチルス菌株を用いた。菌株は大豆発酵液体培地に37℃で36時間前培養した。病原性カビ及び食中毒誘発細菌がローン細胞(lawn cell)となっている寒天固体培地に直径8mmのペーパーディスクを載せ、前培養した菌株を接種した。12時間培養し、その後培地に接種した菌株の周囲に真菌類及び細菌に対して同時に透明な円を形成する菌株を選別した。
当業界で公知の通常の方法により、前記選別した菌株の16S rDNAとgyrAの塩基配列を分析した。塩基配列は、NCBIのBLASTを用いて、GenBankデータベースと、選別した菌株の16S rDNAの塩基配列(配列番号1)及びgyrAの塩基配列(配列番号2)とを比較した。その結果、本菌株の16S rDNA塩基配列はバチルス・ベレゼンシスと99%の相同性を示し、gyrA塩基配列はバチルス・ベレゼンシスと100%の相同性を示した。
配列番号1:
配列番号2:
新たに分離したバチルス・ベレゼンシスCJBVが産生する抗菌物質を分離するための実験を行った。その過程を図1に示す。
新たに分離したバチルス・ベレゼンシスCJBVが真菌類及び食中毒誘発細菌に対して抑制する効果があるか否かを確認するために、次の抗菌活性実験を行った。
まず、カビであるコレトトリカム・オルビクラレ、フザリウム・オキシスポラムf.sp.ライコペルシシJCM12575(Fusarium oxysporum f.sp. lycopersici JCM12575)、カンジダ・アルビカンス、病原性酵母であるジゴサッカロマイセス・バイリに対して新たに分離したバチルス・ベレゼンシスCJBVが抗菌活性を示すか実験した。
また、新たに分離したバチルス・ベレゼンシスCJBVが発酵食品において食中毒誘発細菌にのみ特異的に抗菌活性を有するか調べるために、次の実験を行った。
受託番号:KCCM11528P
受託日:20140417
Claims (2)
- 前記抗菌組成物は、バチルス・セレウス(Bacillus cereus)、リステリア・モノサイトゲネス(Listeria monocytogenes)又はそれらの組み合わせの生育を制御する、請求項1に記載の抗菌組成物。
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KR10-2014-0058846 | 2014-05-16 | ||
KR1020140058846A KR101629551B1 (ko) | 2014-05-16 | 2014-05-16 | 신규한 바실러스 벨레젠시스 cjbv 및 이를 포함하는 항균 조성물 |
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JP2015099658A Active JP6116615B2 (ja) | 2014-05-16 | 2015-05-15 | 新規なバチルス・ベレゼンシスcjbv及びそれを含む抗菌組成物 |
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JP2018229921A Active JP6672441B2 (ja) | 2014-05-16 | 2018-12-07 | 新規なバチルス・ベレゼンシスcjbv及びそれを含む抗菌組成物 |
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JP2015099658A Active JP6116615B2 (ja) | 2014-05-16 | 2015-05-15 | 新規なバチルス・ベレゼンシスcjbv及びそれを含む抗菌組成物 |
JP2017022327A Active JP6480486B2 (ja) | 2014-05-16 | 2017-02-09 | 新規なバチルス・ベレゼンシスcjbv及びそれを含む抗菌組成物 |
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KR102606636B1 (ko) * | 2021-01-29 | 2023-11-29 | 주식회사 농협사료 | 근감소증 예방 또는 개선 효과를 갖는 바실러스 벨레젠시스 및 이의 용도 |
KR102634045B1 (ko) * | 2021-08-31 | 2024-02-05 | 순천향대학교 산학협력단 | 다환 방향족 탄화수소 분해능을 가지는 신규한 바실러스 벨레젠시스, 이의 배양액 및 이들의 용도 |
KR102546973B1 (ko) * | 2021-10-20 | 2023-06-26 | 주식회사 리빙진 | 바실러스 밸레젠시스 Kh2-2 균주를 포함하는 면역증강용 조성물 |
CN114107124B (zh) * | 2021-12-01 | 2023-06-23 | 江西农业大学 | 一株贝莱斯芽孢杆菌d-1及其制剂和应用 |
CN114395509B (zh) * | 2022-01-26 | 2023-06-30 | 杭州师范大学 | 一种从温郁金中分离的芽孢杆菌wyj-e14及其在制备抗肿瘤药物中的应用 |
CN114890552A (zh) * | 2022-04-22 | 2022-08-12 | 天津科技大学 | 一株多功能贝莱斯芽孢杆菌ap3菌株在盐碱水凡纳滨对虾养殖中的应用 |
CN114836351B (zh) * | 2022-05-19 | 2023-04-07 | 河北省科学院生物研究所 | 杀虫防病复合微生物菌剂及包含该菌剂的生物肥料 |
CN115161234B (zh) * | 2022-07-07 | 2023-09-05 | 安徽农业大学 | 一株贝莱斯芽孢杆菌及其在青贮防腐的应用 |
KR20240055598A (ko) * | 2022-10-18 | 2024-04-29 | 케이디바이오 주식회사 | 신규 바실러스 벨레젠시스 균주 및 이의 용도 |
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DE19641213B4 (de) * | 1996-09-26 | 2006-02-16 | Peter Dr. Bendzko | Cyclische Peptide, Verfahren zu ihrer Herstellung und ihre Verwendung |
JPH11285378A (ja) * | 1997-12-01 | 1999-10-19 | Eisai Co Ltd | 抗菌作用を有する新規枯草菌 |
US20100008893A1 (en) * | 2008-07-11 | 2010-01-14 | Novozymes A/S | Bacillus velezensis strain |
KR101163986B1 (ko) * | 2009-04-22 | 2012-07-09 | 한국화학연구원 | 바실러스 벨레젠시스 g341 균주 및 이를 이용한 식물병 방제방법 |
PT2796044T (pt) * | 2011-12-22 | 2016-08-29 | Sds Biotech Corp | Agente de controlo de doenças de plantas |
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KR101629551B1 (ko) | 2016-06-13 |
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JP2016000031A (ja) | 2016-01-07 |
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