JP6516829B2 - 第viii因子製剤 - Google Patents
第viii因子製剤 Download PDFInfo
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- JP6516829B2 JP6516829B2 JP2017506297A JP2017506297A JP6516829B2 JP 6516829 B2 JP6516829 B2 JP 6516829B2 JP 2017506297 A JP2017506297 A JP 2017506297A JP 2017506297 A JP2017506297 A JP 2017506297A JP 6516829 B2 JP6516829 B2 JP 6516829B2
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
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EP14179732 | 2014-08-04 | ||
EP14179732.4 | 2014-08-04 | ||
PCT/EP2015/066999 WO2016020210A1 (en) | 2014-08-04 | 2015-07-24 | Csl behring gmbh |
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JP2017528440A JP2017528440A (ja) | 2017-09-28 |
JP6516829B2 true JP6516829B2 (ja) | 2019-05-22 |
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JP2017506297A Active JP6516829B2 (ja) | 2014-08-04 | 2015-07-24 | 第viii因子製剤 |
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US (1) | US10238718B2 (es) |
EP (1) | EP3177317B1 (es) |
JP (1) | JP6516829B2 (es) |
KR (1) | KR102192494B1 (es) |
CN (1) | CN106687126B (es) |
AU (1) | AU2015299224B2 (es) |
BR (1) | BR112017002090B1 (es) |
CA (1) | CA2956412A1 (es) |
DK (1) | DK3177317T3 (es) |
ES (1) | ES2788870T3 (es) |
IL (1) | IL250343B (es) |
MX (1) | MX2017000862A (es) |
NZ (1) | NZ729629A (es) |
PL (1) | PL3177317T3 (es) |
RU (1) | RU2689338C2 (es) |
SG (2) | SG11201700550YA (es) |
WO (1) | WO2016020210A1 (es) |
Families Citing this family (7)
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CN106279437B (zh) * | 2016-08-19 | 2017-10-31 | 安源医药科技(上海)有限公司 | 高糖基化人凝血因子viii融合蛋白及其制备方法与用途 |
US11142553B2 (en) | 2016-11-29 | 2021-10-12 | Spiber Inc. | Protein composition, method for producing same and method for improving heat stability |
WO2018132874A1 (en) * | 2017-01-19 | 2018-07-26 | Csl Limited | Method of preventing an immune response with alpha- 1 anti-trypsin |
WO2019094521A1 (en) | 2017-11-07 | 2019-05-16 | Rani Therapeutics, Llc | Clotting factor preparations for delivery into tissue of the intestinal tract using a swallowable drug delivery device |
CN110950964B (zh) * | 2018-09-26 | 2021-06-18 | 安源医药科技(上海)有限公司 | 突变型单链人凝血因子viii融合蛋白及其制备方法与用途 |
CN112138149A (zh) * | 2019-06-28 | 2020-12-29 | 北京基科晟斯医药科技有限公司 | 重组凝血因子viii制剂 |
US20220380439A1 (en) | 2020-11-09 | 2022-12-01 | Takeda Pharmaceutical Company Limited | Purification of fviii from plasma using silicon oxide adsorption |
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BRPI0921429B1 (pt) | 2008-11-07 | 2022-07-12 | Takeda Pharmaceutical Company Limited | Formulação farmacêutica liofilizada estável, e, método para preparar um fator liofilizado estável |
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2015
- 2015-07-24 PL PL15741220T patent/PL3177317T3/pl unknown
- 2015-07-24 RU RU2017106159A patent/RU2689338C2/ru active
- 2015-07-24 NZ NZ729629A patent/NZ729629A/en unknown
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- 2015-07-24 BR BR112017002090-4A patent/BR112017002090B1/pt active IP Right Grant
- 2015-07-24 SG SG11201700550YA patent/SG11201700550YA/en unknown
- 2015-07-24 WO PCT/EP2015/066999 patent/WO2016020210A1/en active Application Filing
- 2015-07-24 CA CA2956412A patent/CA2956412A1/en active Pending
- 2015-07-24 KR KR1020177006119A patent/KR102192494B1/ko active IP Right Grant
- 2015-07-24 SG SG10201900598TA patent/SG10201900598TA/en unknown
- 2015-07-24 AU AU2015299224A patent/AU2015299224B2/en active Active
- 2015-07-24 JP JP2017506297A patent/JP6516829B2/ja active Active
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KR102192494B1 (ko) | 2020-12-18 |
JP2017528440A (ja) | 2017-09-28 |
AU2015299224A1 (en) | 2017-03-23 |
CN106687126A (zh) | 2017-05-17 |
MX2017000862A (es) | 2017-05-01 |
DK3177317T3 (en) | 2020-06-15 |
EP3177317A1 (en) | 2017-06-14 |
WO2016020210A1 (en) | 2016-02-11 |
EP3177317B1 (en) | 2020-03-18 |
SG10201900598TA (en) | 2019-02-27 |
SG11201700550YA (en) | 2017-02-27 |
CN106687126B (zh) | 2020-07-28 |
AU2015299224B2 (en) | 2019-06-20 |
BR112017002090B1 (pt) | 2021-06-01 |
PL3177317T3 (pl) | 2020-07-27 |
KR20170040327A (ko) | 2017-04-12 |
RU2017106159A (ru) | 2018-09-06 |
WO2016020210A8 (en) | 2016-04-28 |
BR112017002090A2 (pt) | 2018-01-30 |
RU2017106159A3 (es) | 2018-11-28 |
IL250343B (en) | 2020-10-29 |
IL250343A0 (en) | 2017-03-30 |
RU2689338C2 (ru) | 2019-05-27 |
CA2956412A1 (en) | 2016-02-11 |
US10238718B2 (en) | 2019-03-26 |
NZ729629A (en) | 2021-12-24 |
ES2788870T3 (es) | 2020-10-23 |
US20170252412A1 (en) | 2017-09-07 |
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