JP4740584B2 - 観察装置 - Google Patents
観察装置 Download PDFInfo
- Publication number
- JP4740584B2 JP4740584B2 JP2004361784A JP2004361784A JP4740584B2 JP 4740584 B2 JP4740584 B2 JP 4740584B2 JP 2004361784 A JP2004361784 A JP 2004361784A JP 2004361784 A JP2004361784 A JP 2004361784A JP 4740584 B2 JP4740584 B2 JP 4740584B2
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- Prior art keywords
- tray
- container
- sample tray
- sample
- culture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/50—Means for positioning or orientating the apparatus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/10—Petri dish
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- Microscoopes, Condenser (AREA)
Description
本実施形態は、細胞を培養しながら観察するための培養観察装置に向けられている。培養観察装置は、実質的に、標本を培養するための培養装置(インキュベーター)と、標本を観察するための顕微鏡とを組み合わせて構成されている。図1は、本発明の第一実施形態による培養観察装置を概略的に示す断面図である。
本実施形態は、培養細胞を観察するための観察装置に向けられている。観察装置は倒立型の顕微鏡装置で構成されている。
Claims (2)
- 培養細胞と培地を収容した容器を保持する標本トレーと、
培養細胞の拡大像を観察するための観察手段と、
標本トレーを観察手段の光軸に直交する平面に沿って移動させるための移動手段と、
標本トレーを移動手段に再現性良く保持するトレー保持手段とを備え、
標本トレーは弾性力を利用して容器を保持する容器保持手段を有し、
トレー保持手段は、標本トレーが取り付けられるトレー取り付け部を含んでおり、トレー取り付け部は、標本トレーを受けるトレー受け部と、トレー受け部から上方に突出している凸部とを有し、凸部は、互いに直交する二つの側面にそれぞれ形成された二つのオスアリと、それら二つの側面のいずれにも非平行な押圧面を有しており、
さらにトレー保持手段は、標本トレーに設けられた、トレー受け部に面接触する凹平面と、凸部の一方のオスアリに接触するメスアリと、凸部の他方のオスアリと接触するボールと、凸部の押圧面を押圧する押圧手段とを含んでいる、観察装置。 - 請求項1において、押圧面は、オスアリをそれぞれ有する二つの側面の二等分線にほぼ直交している、観察装置。
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004361784A JP4740584B2 (ja) | 2004-12-14 | 2004-12-14 | 観察装置 |
EP05026873A EP1672405B1 (en) | 2004-12-14 | 2005-12-08 | Observation apparatus |
DE602005015929T DE602005015929D1 (de) | 2004-12-14 | 2005-12-08 | Beobachtungsgerät |
US11/302,591 US7595188B2 (en) | 2004-12-14 | 2005-12-12 | Observation apparatus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004361784A JP4740584B2 (ja) | 2004-12-14 | 2004-12-14 | 観察装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2006171227A JP2006171227A (ja) | 2006-06-29 |
JP4740584B2 true JP4740584B2 (ja) | 2011-08-03 |
Family
ID=35583542
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004361784A Expired - Fee Related JP4740584B2 (ja) | 2004-12-14 | 2004-12-14 | 観察装置 |
Country Status (4)
Country | Link |
---|---|
US (1) | US7595188B2 (ja) |
EP (1) | EP1672405B1 (ja) |
JP (1) | JP4740584B2 (ja) |
DE (1) | DE602005015929D1 (ja) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2007105363A1 (ja) * | 2006-03-14 | 2009-07-30 | 株式会社ニコン | 培養観察装置 |
JP4923716B2 (ja) * | 2006-05-11 | 2012-04-25 | 株式会社日立製作所 | 試料分析装置および試料分析方法 |
WO2007149525A2 (en) * | 2006-06-22 | 2007-12-27 | Manhattan Diagnostics Corp. | Petri dish with filter |
KR100946643B1 (ko) * | 2007-11-30 | 2010-03-09 | 코아스템(주) | 세포배양장치 및 이를 구비한 대용량 자동화 세포배양기 |
KR100932861B1 (ko) * | 2007-11-30 | 2009-12-21 | 코아스템(주) | 세포배양플라스크 |
WO2009111877A1 (en) * | 2008-03-13 | 2009-09-17 | Yu Sun | Method and apparatus for microscopy |
KR101102300B1 (ko) | 2009-06-19 | 2012-01-03 | 전자부품연구원 | 세포 관찰 장치 |
JP2013019919A (ja) * | 2009-10-30 | 2013-01-31 | Hamamatsu Photonics Kk | 撮像ユニット |
JP5495264B2 (ja) * | 2010-03-17 | 2014-05-21 | パナソニックヘルスケア株式会社 | 容器トレー、トレーベース、及び観察ユニット |
KR101505874B1 (ko) * | 2012-12-05 | 2015-03-25 | (주)옵토레인 | 온 칩 세포배양 관찰장치 및 온 칩 세포배양 관찰키트 |
ITTO20121085A1 (it) * | 2012-12-17 | 2014-06-18 | Davide Maselli | Dispositivo e metodo per la selezione cellulare |
JP6277103B2 (ja) * | 2014-09-30 | 2018-02-07 | 富士フイルム株式会社 | 細胞培養観察装置および方法 |
EP3341466A1 (en) * | 2015-08-25 | 2018-07-04 | General Electric Company | Improvements in and relating to biomanufacturing apparatus |
CN106483312B (zh) * | 2015-08-26 | 2018-03-13 | 广明光电股份有限公司 | 生物检测的转动装置 |
JP2017090576A (ja) * | 2015-11-05 | 2017-05-25 | オリンパス株式会社 | 観察装置、及び、観察方法 |
JP6514832B2 (ja) * | 2016-09-29 | 2019-05-15 | オリンパス株式会社 | 観察装置 |
CN106916738B (zh) * | 2017-04-10 | 2019-04-12 | 新昌县博衍智能科技有限公司 | 一种超净工作台用辅助实验装置 |
CN110567874A (zh) * | 2019-09-29 | 2019-12-13 | 深圳赛动生物自动化有限公司 | 细胞培养结果自动观察机构及其工作方法 |
CN113049592B (zh) * | 2021-03-26 | 2022-04-15 | 湖南师范大学 | 一种胆管癌细胞增殖观察设备 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5756812A (en) * | 1980-07-25 | 1982-04-05 | Zeiss Stiftung | Object holder for inversion type microscope |
JP2000098254A (ja) * | 1998-09-21 | 2000-04-07 | Olympus Optical Co Ltd | 光路切替え装置 |
JP2003107364A (ja) * | 2001-09-27 | 2003-04-09 | Tokai Hit:Kk | 顕微鏡観察用培養器 |
JP2003248176A (ja) * | 2001-12-19 | 2003-09-05 | Olympus Optical Co Ltd | 顕微鏡画像撮影装置 |
JP2004021006A (ja) * | 2002-06-18 | 2004-01-22 | Nikon Corp | 顕微鏡 |
JP2004141143A (ja) * | 2002-08-28 | 2004-05-20 | Tokai Hit:Kk | 顕微鏡観察用培養器 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2120404A (en) * | 1937-05-17 | 1938-06-14 | Paper Chemistry Inst | Sample holder |
GB699059A (en) * | 1950-11-25 | 1953-10-28 | Tno | Devices for the determination of the mobility of small particles |
US3997404A (en) * | 1974-06-07 | 1976-12-14 | Johnston Laboratories, Inc. | Method and apparatus for characterizing biologically active agents |
DD209295A1 (de) * | 1982-08-02 | 1984-04-25 | Joachim Bergner | Objekttisch fuer reflexions-mikroskopphotometer |
JPS6192561A (ja) * | 1984-10-09 | 1986-05-10 | Kobayashi Seiyaku Kk | 細菌培養用シヤ−レ |
US5134070A (en) * | 1990-06-04 | 1992-07-28 | Casnig Dael R | Method and device for cell cultivation on electrodes |
JPH09318506A (ja) * | 1996-05-27 | 1997-12-12 | Olympus Optical Co Ltd | ペトリ皿載置装置 |
DE19733990A1 (de) * | 1997-08-06 | 1999-02-11 | Zeiss Carl Jena Gmbh | Stereomikroskop mit einem Probenwechsler |
JPH11202213A (ja) | 1998-01-08 | 1999-07-30 | Nikon Corp | 顕微鏡の標本ホルダ |
US6219180B1 (en) * | 1999-04-13 | 2001-04-17 | Olympus America, Inc. | Optical unit switching apparatus |
US20020131167A1 (en) * | 2000-11-09 | 2002-09-19 | Nguyen Francis T. | Sample holder for an imaging system |
US7799559B2 (en) * | 2003-10-24 | 2010-09-21 | Olympus Corporation | Culture microscope apparatus |
-
2004
- 2004-12-14 JP JP2004361784A patent/JP4740584B2/ja not_active Expired - Fee Related
-
2005
- 2005-12-08 DE DE602005015929T patent/DE602005015929D1/de active Active
- 2005-12-08 EP EP05026873A patent/EP1672405B1/en not_active Expired - Fee Related
- 2005-12-12 US US11/302,591 patent/US7595188B2/en not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5756812A (en) * | 1980-07-25 | 1982-04-05 | Zeiss Stiftung | Object holder for inversion type microscope |
JP2000098254A (ja) * | 1998-09-21 | 2000-04-07 | Olympus Optical Co Ltd | 光路切替え装置 |
JP2003107364A (ja) * | 2001-09-27 | 2003-04-09 | Tokai Hit:Kk | 顕微鏡観察用培養器 |
JP2003248176A (ja) * | 2001-12-19 | 2003-09-05 | Olympus Optical Co Ltd | 顕微鏡画像撮影装置 |
JP2004021006A (ja) * | 2002-06-18 | 2004-01-22 | Nikon Corp | 顕微鏡 |
JP2004141143A (ja) * | 2002-08-28 | 2004-05-20 | Tokai Hit:Kk | 顕微鏡観察用培養器 |
Also Published As
Publication number | Publication date |
---|---|
EP1672405B1 (en) | 2009-08-12 |
DE602005015929D1 (de) | 2009-09-24 |
JP2006171227A (ja) | 2006-06-29 |
EP1672405A1 (en) | 2006-06-21 |
US20060128005A1 (en) | 2006-06-15 |
US7595188B2 (en) | 2009-09-29 |
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