JP4046379B2 - ジヒドロピリジン化合物 - Google Patents

ジヒドロピリジン化合物 Download PDF

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Publication number
JP4046379B2
JP4046379B2 JP26379996A JP26379996A JP4046379B2 JP 4046379 B2 JP4046379 B2 JP 4046379B2 JP 26379996 A JP26379996 A JP 26379996A JP 26379996 A JP26379996 A JP 26379996A JP 4046379 B2 JP4046379 B2 JP 4046379B2
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JP
Japan
Prior art keywords
group
ester
compound
propyl
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP26379996A
Other languages
English (en)
Japanese (ja)
Other versions
JPH09268177A (ja
Inventor
昭 木上
輝久 三浦
成之 田坂
Original Assignee
興和創薬株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 興和創薬株式会社 filed Critical 興和創薬株式会社
Priority to JP26379996A priority Critical patent/JP4046379B2/ja
Priority to PCT/JP1997/000084 priority patent/WO1997028125A1/fr
Publication of JPH09268177A publication Critical patent/JPH09268177A/ja
Application granted granted Critical
Publication of JP4046379B2 publication Critical patent/JP4046379B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
JP26379996A 1996-01-29 1996-09-13 ジヒドロピリジン化合物 Expired - Fee Related JP4046379B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP26379996A JP4046379B2 (ja) 1996-01-29 1996-09-13 ジヒドロピリジン化合物
PCT/JP1997/000084 WO1997028125A1 (fr) 1996-01-29 1997-01-17 Derives de dihydropyridine et compositions medicinales les contenant

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3308896 1996-01-29
JP8-33088 1996-01-29
JP26379996A JP4046379B2 (ja) 1996-01-29 1996-09-13 ジヒドロピリジン化合物

Publications (2)

Publication Number Publication Date
JPH09268177A JPH09268177A (ja) 1997-10-14
JP4046379B2 true JP4046379B2 (ja) 2008-02-13

Family

ID=26371729

Family Applications (1)

Application Number Title Priority Date Filing Date
JP26379996A Expired - Fee Related JP4046379B2 (ja) 1996-01-29 1996-09-13 ジヒドロピリジン化合物

Country Status (2)

Country Link
JP (1) JP4046379B2 (fr)
WO (1) WO1997028125A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306853B1 (en) 1998-02-10 2001-10-23 Nikken Chemicals Co., Ltd. 1,4-Dihydropyridine derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0692391B2 (ja) * 1987-07-17 1994-11-16 インステイテユト オルガニチエスコゴ シンテザ，アカデミヤ ナウク ラトビイスコイ エスエスエ−ル １，４−ジヒドロピリジン誘導体
JPH0692401B2 (ja) * 1987-07-17 1994-11-16 インステイテユト オルガニチエスコゴ シンテザ，アカデミヤ ナウク ラトビイスコイ エスエスエ−ル １，４−ジヒドロピリジン誘導体
JP2640245B2 (ja) * 1988-07-28 1997-08-13 日研化学株式会社 １，４−ジヒドロピリジン誘導体
JP2678786B2 (ja) * 1989-03-14 1997-11-17 日研化学株式会社 １，４―ジヒドロピリジン誘導体
JP2850376B2 (ja) * 1988-08-02 1999-01-27 日産化学工業株式会社 抗癌剤薬効増強剤
JPH05117235A (ja) * 1991-04-26 1993-05-14 Ajinomoto Co Inc 新規１，４−ジヒドロピリジン誘導体及びそれを含有する癌耐性克服剤
WO1996004268A1 (fr) * 1994-07-29 1996-02-15 Nikken Chemicals Co., Ltd. Compose de 1,4-dihydropyridine et composition medicinale contenant ledit compose

Also Published As

Publication number Publication date
WO1997028125A1 (fr) 1997-08-07
JPH09268177A (ja) 1997-10-14

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