JP2022037217A - 患者熱交換システム用の高分子膜および統合された入口および出口管を有する流体カセット - Google Patents
患者熱交換システム用の高分子膜および統合された入口および出口管を有する流体カセット Download PDFInfo
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Abstract
Description
[項目1]
周辺部および上記周辺部によって完全に囲まれた開口を定めるフレーム(52)であって、上記フレーム(52)は、2つのコールドプレート(30、32)間に密接に受け入れられるように構成され、上記フレーム(52)は、上記フレーム(52)を通って上記開口に入るそれぞれの流体通路を確立する少なくとも流体入口(56)および流体出口(60)を有し、上記流体入口(56)および上記流体出口(60)は、患者に係合可能な熱交換部材(12、18)と関連したそれぞれの流体戻りおよび供給ライン(L3、L4)と流体連通するように構成される、フレーム(52)、および、
上記フレーム(52)に接続されて、上記開口を完全にブロックする膜アセンブリ(64)であって、上記膜アセンブリ(64)は、第2の膜(68)との間に作動流体室を有して上記第2の膜(68)に平行な第1の膜(66)を含み、上記流体入口(56)および上記流体出口(60)は、上記膜(66、68)間の上記作動流体室と連通し、上記作動流体室は、流体の少なくとも一部が上記流体入口と流体出口との間で流体の上記少なくとも一部の流れを妨げるかまたは向け直す直線または曲線の壁を有さずに上記流体入口から上記作動流体室を通って上記流体出口まで流れることができるように構成される、膜アセンブリ(64)、
を備える、デバイス。
[項目2]
上記熱交換部材(12、18)は、血管内熱交換カテーテル(12)を含む、項目1に記載のデバイス。
[項目3]
上記熱交換部材(12、18)は、患者と外部的に係合可能な熱交換パッド(18)を含む、項目1に記載のデバイス。
[項目4]
上記熱交換部材(12、18)から循環する作動流体で満たされるときに、上記作動流体室は、膨張可能である、項目1に記載のデバイス。
[項目5]
各膜(66、68)は、厚さ2ミル(0.002")以下である、項目1に記載のデバイス。
[項目6]
各膜(66、68)は、1ミルと2ミルの間(0.001"~0.002")の厚さである、項目5に記載のデバイス。
[項目7]
上記膜(66、68)は、上記フレーム(52)上に引張状態で取り付けられる、項目1に記載のデバイス。
[項目8]
上記膜(66、68)は、上記フレーム(52)上のポスト(70)を通じて延伸される、項目7に記載のデバイス。
[項目9]
上記開口は、直線で構成される、項目1に記載のデバイス。
[項目10]
上記開口は、上部、上記上部から間隔を置かれて、上記上部に平行な底部エッジ、上記上部と上記底部との間を延びる左側部、および、上記上部と上記底部との間を延びて、上記左側部に平行な右側部、を定め、上記左側部および上記右側部は、第1の長さを定め、上記上部および上記底部は、第2の長さを定め、上記第1の長さは、上記第2の長さ±上記第2の長さの10パーセントに等しい、項目9に記載のデバイス。
[項目11]
上記第1の長さは、上記第2の長さにほぼ等しい、項目10に記載のデバイス。
[項目12]
上記膜アセンブリ(64)は、上記フレーム(52)と並置される直線で構成される境界(74)を定め、上記境界(74)は、第1および第2の膜(66、68)、ならびに、上記第1および第2の膜(66、68)と係合して、上記境界(74)を過ぎて径方向内向きに延びない少なくとも1つの補強層を含む、項目1に記載のデバイス。
[項目13]
上記流体入口(56)および上記流体出口(60)は、それぞれの入口管および出口管(58、62)によって少なくとも部分的に定められ、上記管(58、62)は、上記膜(66、68)に熱溶着される、項目1に記載のデバイス。
[項目14]
上記開口は、上部、上記上部から間隔を置かれて、上記上部に平行な底部エッジ、上記上部と上記底部との間を延びる左側部、および、上記上部と上記底部との間を延びて、上記左側部に平行な右側部、を定め、上記管(58、62)は、上記開口の上記左側部および右側部に沿って上記上部へとそれぞれ延びる、項目13に記載のデバイス。
[項目15]
上記管(58、62)は、上記開口の上記上部に隣接して配置されるそれぞれの管の端部で終端する、項目14に記載のデバイス。
[項目16]
上記管(58、62)は、上記開口の上記底部に隣接して配置されるそれぞれの管の端部で終端する、項目14に記載のデバイス。
[項目17]
上記管(58、62)のうちの第1のものは、それぞれの第1の管の端部で終端し、上記管(58、62)のうちの第2のものは、それぞれの第2の管の端部で終端し、上記第2の管の端部は、上記第1の管の端部よりも上記開口の上記底部の近くに配置される、項目14に記載のデバイス。
[項目18]
フレーム(52)締結具穴が形成される少なくとも1つの溶接継ぎ目を確立するために、上記膜(66、68)を補強する高分子フィルムの少なくとも1つの層を備える、項目1に記載のデバイス。
[項目19]
互いに密接に間隔を置いて配置される2つのそして2つだけの膜(66、68)によって定められる、直線で囲まれる、正方形のまたは正方形に近い作動流体室、および、
上記作動流体室の少なくとも部分に接して、上記膜(66、68)を保持する中空フレーム(52)であって、上記中空フレーム(52)は、流体が作動流体室内へとおよび/またはそれから外へと通過することができる少なくとも1つの流体通路を定める、中空フレーム(52)、および、上記流体通路を通って上記作動流体室に作動流体を運ぶために上記膜(66、68)に結合される入口管、を備え、
装置が熱交換器の熱交換面(30、32)の間に配置されて、作動流体が上記作動流体室を満たすときに、上記作動流体室は、上記作動流体との熱交換を容易にするために上記熱交換面(30、32)に対して膨張する、装置。
[項目20]
上記作動流体室から作動流体を運び出すために、上記作動流体室と連通して、上記膜(66、68)に結合される出口管(62)をさらに備え、上記出口管は上記作動流体室の上記流体出口を定める、項目19に記載の装置。
[項目21]
正方形の膜アセンブリ(64)の3つの側部をフレーム(52)と係合するステップであって、上記膜アセンブリは作動流体室を定める、ステップ、
作動流体を上記膜アセンブリ(64)に運び入れるために入口管(58)を上記フレーム(52)と係合するステップ、
作動流体を上記膜アセンブリ(64)から運び出すために出口管(62)を上記フレーム(52)と係合するステップ、を含み、
上記入口管または出口管(58、62)のうちの第1の1つは、それぞれの第1の管の端部で終端し、上記入口管または出口管(58、62)のうちの第2の1つは、それぞれの第2の管の端部で終端し、上記第2の管の端部は、上記第1の管の端部に比べて上記作動流体室の底部により近い位置に配置される、方法。
Claims (21)
- 周辺部および前記周辺部によって完全に囲まれた開口を定めるフレーム(52)であって、前記フレーム(52)は、2つのコールドプレート(30、32)間に密接に受け入れられるように構成され、前記フレーム(52)は、前記フレーム(52)を通って前記開口に入るそれぞれの流体通路を確立する少なくとも流体入口(56)および流体出口(60)を有し、前記流体入口(56)および前記流体出口(60)は、患者に係合可能な熱交換部材(12、18)と関連したそれぞれの流体戻りおよび供給ライン(L3、L4)と流体連通するように構成される、フレーム(52)、および、
前記フレーム(52)に接続されて、前記開口を完全にブロックする膜アセンブリ(64)であって、前記膜アセンブリ(64)は、第2の膜(68)との間に作動流体室を有して前記第2の膜(68)に平行な第1の膜(66)を含み、前記流体入口(56)および前記流体出口(60)は、前記膜(66、68)間の前記作動流体室と連通し、前記作動流体室は、流体の少なくとも一部が前記流体入口と流体出口との間で流体の前記少なくとも一部の流れを妨げるかまたは向け直す直線または曲線の壁を有さずに前記流体入口から前記作動流体室を通って前記流体出口まで流れることができるように構成される、膜アセンブリ(64)、
を備える、デバイス。 - 前記熱交換部材(12、18)は、血管内熱交換カテーテル(12)を含む、請求項1に記載のデバイス。
- 前記熱交換部材(12、18)は、患者と外部的に係合可能な熱交換パッド(18)を含む、請求項1に記載のデバイス。
- 前記熱交換部材(12、18)から循環する作動流体で満たされるときに、前記作動流体室は、膨張可能である、請求項1に記載のデバイス。
- 各膜(66、68)は、厚さ2ミル(0.002")以下である、請求項1に記載のデバイス。
- 各膜(66、68)は、1ミルと2ミルの間(0.001"~0.002")の厚さである、請求項5に記載のデバイス。
- 前記膜(66、68)は、前記フレーム(52)上に引張状態で取り付けられる、請求項1に記載のデバイス。
- 前記膜(66、68)は、前記フレーム(52)上のポスト(70)を通じて延伸される、請求項7に記載のデバイス。
- 前記開口は、直線で構成される、請求項1に記載のデバイス。
- 前記開口は、上部、前記上部から間隔を置かれて、前記上部に平行な底部エッジ、前記上部と前記底部との間を延びる左側部、および、前記上部と前記底部との間を延びて、前記左側部に平行な右側部、を定め、前記左側部および前記右側部は、第1の長さを定め、前記上部および前記底部は、第2の長さを定め、前記第1の長さは、前記第2の長さ±前記第2の長さの10パーセントに等しい、請求項9に記載のデバイス。
- 前記第1の長さは、前記第2の長さにほぼ等しい、請求項10に記載のデバイス。
- 前記膜アセンブリ(64)は、前記フレーム(52)と並置される直線で構成される境界(74)を定め、前記境界(74)は、第1および第2の膜(66、68)、ならびに、前記第1および第2の膜(66、68)と係合して、前記境界(74)を過ぎて径方向内向きに延びない少なくとも1つの補強層を含む、請求項1に記載のデバイス。
- 前記流体入口(56)および前記流体出口(60)は、それぞれの入口管および出口管(58、62)によって少なくとも部分的に定められ、前記管(58、62)は、前記膜(66、68)に熱溶着される、請求項1に記載のデバイス。
- 前記開口は、上部、前記上部から間隔を置かれて、前記上部に平行な底部エッジ、前記上部と前記底部との間を延びる左側部、および、前記上部と前記底部との間を延びて、前記左側部に平行な右側部、を定め、前記管(58、62)は、前記開口の前記左側部および右側部に沿って前記上部へとそれぞれ延びる、請求項13に記載のデバイス。
- 前記管(58、62)は、前記開口の前記上部に隣接して配置されるそれぞれの管の端部で終端する、請求項14に記載のデバイス。
- 前記管(58、62)は、前記開口の前記底部に隣接して配置されるそれぞれの管の端部で終端する、請求項14に記載のデバイス。
- 前記管(58、62)のうちの第1のものは、それぞれの第1の管の端部で終端し、前記管(58、62)のうちの第2のものは、それぞれの第2の管の端部で終端し、前記第2の管の端部は、前記第1の管の端部よりも前記開口の前記底部の近くに配置される、請求項14に記載のデバイス。
- フレーム(52)締結具穴が形成される少なくとも1つの溶接継ぎ目を確立するために、前記膜(66、68)を補強する高分子フィルムの少なくとも1つの層を備える、請求項1に記載のデバイス。
- 互いに密接に間隔を置いて配置される2つのそして2つだけの膜(66、68)によって定められる、直線で囲まれる、正方形のまたは正方形に近い作動流体室、および、
前記作動流体室の少なくとも部分に接して、前記膜(66、68)を保持する中空フレーム(52)であって、前記中空フレーム(52)は、流体が作動流体室内へとおよび/またはそれから外へと通過することができる少なくとも1つの流体通路を定める、中空フレーム(52)、および、前記流体通路を通って前記作動流体室に作動流体を運ぶために前記膜(66、68)に結合される入口管、を備え、
装置が熱交換器の熱交換面(30、32)の間に配置されて、作動流体が前記作動流体室を満たすときに、前記作動流体室は、前記作動流体との熱交換を容易にするために前記熱交換面(30、32)に対して膨張する、装置。 - 前記作動流体室から作動流体を運び出すために、前記作動流体室と連通して、前記膜(66、68)に結合される出口管(62)をさらに備え、前記出口管は前記作動流体室の前記流体出口を定める、請求項19に記載の装置。
- 正方形の膜アセンブリ(64)の3つの側部をフレーム(52)と係合するステップであって、前記膜アセンブリは作動流体室を定める、ステップ、
作動流体を前記膜アセンブリ(64)に運び入れるために入口管(58)を前記フレーム(52)と係合するステップ、
作動流体を前記膜アセンブリ(64)から運び出すために出口管(62)を前記フレーム(52)と係合するステップ、を含み、
前記入口管または出口管(58、62)のうちの第1の1つは、それぞれの第1の管の端部で終端し、前記入口管または出口管(58、62)のうちの第2の1つは、それぞれの第2の管の端部で終端し、前記第2の管の端部は、前記第1の管の端部に比べて前記作動流体室の底部により近い位置に配置される、方法。
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2014
- 2014-02-14 US US14/180,655 patent/US10792185B2/en active Active
- 2014-10-03 JP JP2016551136A patent/JP6397038B2/ja active Active
- 2014-10-03 EP EP19164951.6A patent/EP3520748B1/en active Active
- 2014-10-03 WO PCT/US2014/059006 patent/WO2015122937A1/en active Application Filing
- 2014-10-03 CA CA2939446A patent/CA2939446A1/en not_active Abandoned
- 2014-10-03 AU AU2014382612A patent/AU2014382612A1/en not_active Abandoned
- 2014-10-03 CN CN201480077206.2A patent/CN106068112A/zh active Pending
- 2014-10-03 CN CN202110929816.2A patent/CN113599057A/zh active Pending
- 2014-10-03 EP EP14882721.5A patent/EP3094290B1/en active Active
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2018
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2020
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US5344436A (en) * | 1990-01-08 | 1994-09-06 | Lake Shore Medical Development Partners, Ltd. | Localized heat transfer device |
JP2003524507A (ja) * | 2000-02-28 | 2003-08-19 | レイディアント メディカル インコーポレイテッド | 血管内熱交換カテーテルの使い捨てカセット |
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EP3094290A4 (en) | 2017-10-04 |
CN113599057A (zh) | 2021-11-05 |
EP3520748B1 (en) | 2023-08-30 |
JP2019010526A (ja) | 2019-01-24 |
WO2015122937A8 (en) | 2015-12-03 |
WO2015122937A1 (en) | 2015-08-20 |
AU2014382612A1 (en) | 2016-08-25 |
US10792185B2 (en) | 2020-10-06 |
EP3094290A1 (en) | 2016-11-23 |
JP7005103B2 (ja) | 2022-01-21 |
US20150230974A1 (en) | 2015-08-20 |
EP3094290B1 (en) | 2019-05-08 |
CN106068112A (zh) | 2016-11-02 |
EP3520748A1 (en) | 2019-08-07 |
CA2939446A1 (en) | 2015-08-20 |
JP2017511716A (ja) | 2017-04-27 |
JP6397038B2 (ja) | 2018-09-26 |
US20210030586A1 (en) | 2021-02-04 |
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