JP2016216078A - 紫外線殺菌方法 - Google Patents
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Abstract
Description
(b)紫外線照射装置の紫外線発光面をセルに密着させて、紫外線発光面から、殺菌処理時と同一の発光条件で発光させた紫外線を、セル内に向けて照射する工程S102;
(c)セルを通過した透過紫外線の放射照度(単位:mW/cm2)を測定する工程S15;
(d)上記工程(a)乃至(c)(S101〜S103)を、異なる光路長を有する複数のセルについて行うことにより、透過紫外線の放射照度と光路長との関係を求める工程S104;
上記工程(d)〜(d)(S104〜S104)において、透過紫外線の放射照度と光路長との関係は、Lambert−Beerの法則に従う。すなわち、透過紫外線の放射照度I1は、光路長Lに対して、次の式(1)の関係にある。
log(I1/I0)=−αL …(1)
式(1)中、I0は媒質に入射する前の波長λの紫外線の放射照度であり、αは被殺菌体と波長λpeakに対応して定まる比例定数(吸光係数)である。一般に、発光ダイオードの発光スペクトルのピーク幅は極めて狭いので、透過紫外線の放射照度の光路長依存性を議論するにあたっては、深紫外線発光ダイオードの発光ピーク波長λpeakにおける吸光係数α(λpeak)のみを考えれば十分である。式(1)は次の式(2)のように変形できる。
logI1=−αL+logI0 …(2)
したがって主ピーク波長λpeakにおける透過紫外線の放射照度I1の対数と、セルの光路長Lとの組を複数得ることにより、主ピーク波長λpeakにおける透過紫外線の放射照度I1と光路長Lとを関係付ける回帰直線を求めることができる(上記(d)工程S104)。回帰直線の算出には例えば最小二乗法等の公知の方法を用いることができる。
110・・・紫外線発光モジュール
111・・・円筒状基体
112、442・・・深紫外線発光素子(DUV−LED)
113・・・冷却媒体用流路
114・・・円筒状基体の中心軸
115・・・深紫外線発光素子の光軸
116・・・カバー
117・・・シール部材
118・・・冷却媒体
120・・・長楕円反射ミラーからなる出射側反射ミラー
121・・・出射側反射ミラーの焦点軸
122・・・出射側反射ミラーの集光軸
123・・・長楕円反射ミラーからなる集光側反射ミラー
124・・・集光側反射ミラーの焦点軸
125・・・出射側筐体
126・・・集光側筐体
130・・・集光紫外線出射ユニット(110及び120の組み合わせ)
140・・・コリメート光学系
150・・・本体
200、210・・・被殺菌体
300、310・・・紫外線透過性容器
400a、400b、401、402、403・・・紫外線照射ユニット
420・・・筐体
430・・・紫外線透過窓
431・・・内側面
432・・・外側面
440・・・光源
441・・・紫外線ランプ
443・・・集光モジュール化光源
450・・・電動モーター
460・・・ガイドレール
Claims (9)
- 被殺菌体を紫外線透過性容器に充填する充填工程、
該充填工程によって被殺菌体が充填された前記容器の外部から紫外線を照射する紫外線照射工程及び
被殺菌体が充填された前記容器を気密に封止する封止工程を含んでなる紫外線殺菌方法であって、
前記封止工程を前記充填工程が終了してから前記紫外線照射工程が終了するまでの間に行うか、又は前記紫外線照射工程及び前記封止工程を同一の無菌環境下で行うことを特徴とする紫外線殺菌方法。 - 前記紫外線透過性容器がヒートシール性樹脂からなる紫外線透過性フィルムを製袋してなる可撓性袋又はヒートシール性樹脂層を含んでなる紫外線透過性積層樹脂フィルムを製袋してなる可撓性袋であり、前記封止工程が前記可撓性袋の開口部をヒートシールすることにより行われる請求項1に記載の方法。
- 前記紫外線照射工程において、前記紫外線透過性容器における“照射された紫外線の光軸が容器を横切る最大長”又は“照射する紫外線強度”を制御して、容器内に充填された被殺菌体の任意の位置における紫外線の放射照度が0.01mW/cm2以上となるようにすることを特徴とする、請求項1又は2に記載の方法。
- 前記紫外線照射工程において、所定の幅の間隙を設けて互いに対向するように配置された一対の隔壁の間の空間に、被殺菌体が充填された前記紫外線透過性容器の表面が前記隔壁と近接又は当接するようにして配置し、前記一対の隔壁の向かい合う2面の一方または両方に設けられた1又は2の紫外線発光面から紫外線を照射する、請求項1乃至3の何れかに記載の方法。
- 被殺菌体が充填された前記紫外線透過性容器の表面の50%以上の面積が前記隔壁と近接又は当接するようにして配置し、前記一対の隔壁の向かい合う2面の両方に設けられた2つの紫外線発光面から夫々紫外線を照射する、請求項4に記載の方法。
- 前記紫外線発光面を、被殺菌体が充填された前記紫外線透過性容器の表面の形状に対応する形状とし、前記紫外線透過性容器の表面の80%以上の面積が前記隔壁と近接又は当接するようにして紫外線照射を行う、請求項5に記載の方法。
- 前記被殺菌体が液状、ペースト状、ゼリー状又はムース状であり、前記紫外線透過性容器がヒートシール性樹脂からなる紫外線透過性フィルムを製袋してなる可撓性袋又はヒートシール性樹脂層を含んでなる紫外線透過性積層樹脂フィルムを製袋してなる可撓性袋であり、前記被殺菌体が充填された前記可撓性袋を、その正面側及び/又は裏面側から前記紫外線発光面により挟圧して当該可撓性袋の厚さが薄くなるように変形させて紫外線照射を行う、請求項4乃至6の何れかに記載の方法。
- 前記封止工程によって封止された前記紫外線透過性容器の外表面に紫外線遮蔽処理を施す紫外線遮蔽工程を更に含んでなることを特徴とする請求項1乃至7の何れかに記載の方法。
- 紫外線殺菌された食品、化粧品、医薬部外品又は医薬品が容器内に封入された容器包装詰物品を製造する方法であって、流動性を有する食品、化粧品、医薬部外品又は医薬品からなる被殺菌体を、請求項1乃至8の何れかの方法により被殺菌体の容器への充填、紫外線殺菌及び容器の封止を行う工程を含んでなることを特徴とする容器包装詰物品の製造方法。
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EP16796461.8A EP3299305A4 (en) | 2015-05-19 | 2016-05-16 | Ultraviolet sterilization method, method for manufacturing container-packaged product, and ultraviolet sterilization device |
PCT/JP2016/064437 WO2016186068A1 (ja) | 2015-05-19 | 2016-05-16 | 紫外線殺菌方法、容器包装詰物品の製造方法及び紫外線殺菌装置 |
US15/575,262 US20180132508A1 (en) | 2015-05-19 | 2016-05-16 | Ultraviolet Sterilization Method, Method of Manufacturing Container-Packaged Product, and Ultraviolet Sterilization Apparatus |
TW105115346A TW201705991A (zh) | 2015-05-19 | 2016-05-18 | 紫外線殺菌方法、容器包裝內容物品的製造方法及紫外線殺菌裝置 |
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Cited By (5)
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DE102017123110A1 (de) * | 2017-10-05 | 2019-04-11 | Lar Process Analysers Ag | Analysevorrichtung |
JP2019098291A (ja) * | 2017-12-07 | 2019-06-24 | スタンレー電気株式会社 | 流体殺菌装置 |
JP2020010830A (ja) * | 2018-07-18 | 2020-01-23 | 旭化成株式会社 | 流体殺菌モジュール |
JP6896919B1 (ja) * | 2020-08-03 | 2021-06-30 | 株式会社クォークテクノロジー | 殺菌ランプ |
WO2023058376A1 (ja) * | 2021-10-05 | 2023-04-13 | 株式会社Reiz | 流体清浄化サーキュレータ |
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WO2018026008A1 (ja) * | 2016-08-05 | 2018-02-08 | 株式会社トクヤマ | 紫外線殺菌方法及び紫外線殺菌装置 |
JP6892788B2 (ja) * | 2017-05-26 | 2021-06-23 | ウシオ電機株式会社 | 殺菌方法、殺菌装置 |
JP6948605B1 (ja) * | 2020-08-05 | 2021-10-13 | ウシオ電機株式会社 | 菌又はウイルスの不活化方法、菌又はウイルスの不活化装置 |
CN116888047A (zh) * | 2021-02-15 | 2023-10-13 | 吉地股份公司 | 用于封装烟草工业制品的机器和方法 |
US20220413310A1 (en) * | 2021-06-29 | 2022-12-29 | Ronald Scott Frazier | Method and Technique for the Focusing of UVC Light Energy to a Focused Energy Beam |
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TW201705991A (zh) | 2017-02-16 |
EP3299305A4 (en) | 2019-01-02 |
US20180132508A1 (en) | 2018-05-17 |
JP6055513B2 (ja) | 2016-12-27 |
WO2016186068A1 (ja) | 2016-11-24 |
EP3299305A1 (en) | 2018-03-28 |
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