JP2015101576A - Skin body sterilizing and washing agent composition - Google Patents
Skin body sterilizing and washing agent composition Download PDFInfo
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- JP2015101576A JP2015101576A JP2013245177A JP2013245177A JP2015101576A JP 2015101576 A JP2015101576 A JP 2015101576A JP 2013245177 A JP2013245177 A JP 2013245177A JP 2013245177 A JP2013245177 A JP 2013245177A JP 2015101576 A JP2015101576 A JP 2015101576A
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- 239000000203 mixture Substances 0.000 title claims abstract description 61
- 230000001954 sterilising effect Effects 0.000 title abstract description 27
- 238000005406 washing Methods 0.000 title abstract description 8
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 claims abstract description 65
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 44
- 239000000194 fatty acid Substances 0.000 claims abstract description 44
- 229930195729 fatty acid Natural products 0.000 claims abstract description 44
- 150000004665 fatty acids Chemical class 0.000 claims abstract description 43
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims abstract description 32
- 125000002252 acyl group Chemical group 0.000 claims abstract description 28
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 11
- 238000004140 cleaning Methods 0.000 claims description 34
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims description 32
- 239000000645 desinfectant Substances 0.000 claims description 28
- 229930195712 glutamate Natural products 0.000 claims description 23
- 239000000417 fungicide Substances 0.000 claims description 20
- 230000000855 fungicidal effect Effects 0.000 claims description 14
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 10
- 239000003240 coconut oil Substances 0.000 claims description 8
- IJALWSVNUBBQRA-UHFFFAOYSA-N 4-Isopropyl-3-methylphenol Chemical compound CC(C)C1=CC=C(O)C=C1C IJALWSVNUBBQRA-UHFFFAOYSA-N 0.000 claims description 7
- 235000019864 coconut oil Nutrition 0.000 claims description 7
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims description 6
- NFIDBGJMFKNGGQ-UHFFFAOYSA-N isopropylmethylphenol Natural products CC(C)CC1=CC=CC=C1O NFIDBGJMFKNGGQ-UHFFFAOYSA-N 0.000 claims description 6
- 229960003500 triclosan Drugs 0.000 claims description 6
- QTDJJSNTSBBCKS-UQKRIMTDSA-N (4s)-4-amino-5-dodecanoyloxy-5-oxopentanoic acid;2-[bis(2-hydroxyethyl)amino]ethanol Chemical compound OCCN(CCO)CCO.CCCCCCCCCCCC(=O)OC(=O)[C@@H](N)CCC(O)=O QTDJJSNTSBBCKS-UQKRIMTDSA-N 0.000 claims description 2
- 239000012459 cleaning agent Substances 0.000 claims description 2
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract description 13
- 235000013922 glutamic acid Nutrition 0.000 abstract description 13
- 239000004220 glutamic acid Substances 0.000 abstract description 13
- 239000003795 chemical substances by application Substances 0.000 abstract description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 19
- 229940049906 glutamate Drugs 0.000 description 18
- 238000002156 mixing Methods 0.000 description 14
- 229960002989 glutamic acid Drugs 0.000 description 13
- -1 polyoxyethylene Polymers 0.000 description 11
- 239000003599 detergent Substances 0.000 description 10
- 230000000052 comparative effect Effects 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 239000007788 liquid Substances 0.000 description 7
- 241000894006 Bacteria Species 0.000 description 6
- 239000002253 acid Substances 0.000 description 6
- 239000004094 surface-active agent Substances 0.000 description 6
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 5
- 241000588724 Escherichia coli Species 0.000 description 4
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 4
- 241000607142 Salmonella Species 0.000 description 4
- 241000191967 Staphylococcus aureus Species 0.000 description 4
- 238000013329 compounding Methods 0.000 description 4
- 230000000249 desinfective effect Effects 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000003945 anionic surfactant Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- GPLRAVKSCUXZTP-UHFFFAOYSA-N diglycerol Chemical compound OCC(O)COCC(O)CO GPLRAVKSCUXZTP-UHFFFAOYSA-N 0.000 description 3
- 150000002169 ethanolamines Chemical class 0.000 description 3
- 239000003002 pH adjusting agent Substances 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 239000003206 sterilizing agent Substances 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- AVBJHQDHVYGQLS-AWEZNQCLSA-N (2s)-2-(dodecanoylamino)pentanedioic acid Chemical compound CCCCCCCCCCCC(=O)N[C@H](C(O)=O)CCC(O)=O AVBJHQDHVYGQLS-AWEZNQCLSA-N 0.000 description 2
- ACCAIGJKLCJFHP-UQKRIMTDSA-N 2-[bis(2-hydroxyethyl)amino]ethanol;(2s)-2-(dodecanoylamino)pentanedioic acid Chemical compound OCCN(CCO)CCO.CCCCCCCCCCCC(=O)N[C@H](C(O)=O)CCC(O)=O ACCAIGJKLCJFHP-UQKRIMTDSA-N 0.000 description 2
- ISPYQTSUDJAMAB-UHFFFAOYSA-N 2-chlorophenol Chemical compound OC1=CC=CC=C1Cl ISPYQTSUDJAMAB-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 125000004442 acylamino group Chemical group 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000000474 nursing effect Effects 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 239000002453 shampoo Substances 0.000 description 2
- 159000000000 sodium salts Chemical class 0.000 description 2
- 238000005063 solubilization Methods 0.000 description 2
- 230000007928 solubilization Effects 0.000 description 2
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 2
- MTJZWYHTZFVEGI-INIZCTEOSA-N (2s)-2-(tetradecanoylamino)pentanedioic acid Chemical compound CCCCCCCCCCCCCC(=O)N[C@H](C(O)=O)CCC(O)=O MTJZWYHTZFVEGI-INIZCTEOSA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- 229940058015 1,3-butylene glycol Drugs 0.000 description 1
- XZGCKHCHBRLXCW-UHFFFAOYSA-N 2,3-dimethyl-5-propan-2-ylphenol Chemical compound CC(C)C1=CC(C)=C(C)C(O)=C1 XZGCKHCHBRLXCW-UHFFFAOYSA-N 0.000 description 1
- AVBJHQDHVYGQLS-UHFFFAOYSA-N 2-(dodecanoylamino)pentanedioic acid Chemical compound CCCCCCCCCCCC(=O)NC(C(O)=O)CCC(O)=O AVBJHQDHVYGQLS-UHFFFAOYSA-N 0.000 description 1
- KEYCFTSZYAYIEE-UQKRIMTDSA-N 2-aminoethanol;(2s)-2-(dodecanoylamino)pentanedioic acid Chemical compound NCCO.CCCCCCCCCCCC(=O)N[C@H](C(O)=O)CCC(O)=O KEYCFTSZYAYIEE-UQKRIMTDSA-N 0.000 description 1
- AXWIKVJVPDHROL-UHFFFAOYSA-N 3,5-dimethyl-2-propan-2-ylphenol Chemical compound CC(C)C1=C(C)C=C(C)C=C1O AXWIKVJVPDHROL-UHFFFAOYSA-N 0.000 description 1
- OSDLLIBGSJNGJE-UHFFFAOYSA-N 4-chloro-3,5-dimethylphenol Chemical compound CC1=CC(O)=CC(C)=C1Cl OSDLLIBGSJNGJE-UHFFFAOYSA-N 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- ATFFFUXLAJBBDE-FQEVSTJZSA-N N-Stearoyl glutamic acid Chemical compound CCCCCCCCCCCCCCCCCC(=O)N[C@H](C(O)=O)CCC(O)=O ATFFFUXLAJBBDE-FQEVSTJZSA-N 0.000 description 1
- 235000019482 Palm oil Nutrition 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000005844 Thymol Substances 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 229940105990 diglycerin Drugs 0.000 description 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 150000002190 fatty acyls Chemical group 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000000693 micelle Substances 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229960000790 thymol Drugs 0.000 description 1
- ICUTUKXCWQYESQ-UHFFFAOYSA-N triclocarban Chemical compound C1=CC(Cl)=CC=C1NC(=O)NC1=CC=C(Cl)C(Cl)=C1 ICUTUKXCWQYESQ-UHFFFAOYSA-N 0.000 description 1
- 229960001325 triclocarban Drugs 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Detergent Compositions (AREA)
Abstract
Description
本発明は、皮膚身体殺菌洗浄剤組成物に関する。 The present invention relates to a skin body disinfectant cleaning composition.
外食産業の厨房、洗面所、食品加工工場、介護施設、病院等において、食中毒予防のために手指の洗浄及び殺菌が行われている。手指の洗浄及び殺菌は、手指を一度洗浄し、その後に殺菌するという方法もあるが、当該施設等の作業者は多忙などを理由に手洗いにかけられる時間が短いため、一度にかつ短時間で洗浄及び殺菌を行うことができることが望ましい。 In kitchens, washrooms, food processing factories, nursing homes, hospitals, etc. in the restaurant industry, fingers are washed and sterilized to prevent food poisoning. Hands can be washed and sterilized by washing the fingers once and then sterilizing them. However, the workers in the facility, etc. have a short time to wash their hands because of their busyness. It is desirable to be able to perform sterilization.
特許文献１には、アシルアミノ酸型アニオン性界面活性剤と両性界面活性剤と、特定分子量のポリエチレングリコールとを含有し、皮膚へのマイルド性、低温安定性及び泡質の改善を図った液体洗浄剤組成物が開示されている。
また、特許文献２においては、アシルアミノ酸トリエタノールアミン塩とその他界面活性剤を含有するポンプフォーマー容器充填用液状洗浄剤組成物が開示されている。
Patent Document 1 discloses a liquid washing containing an acylamino acid type anionic surfactant, an amphoteric surfactant and a polyethylene glycol having a specific molecular weight, and improving mildness to skin, low temperature stability and foam quality. An agent composition is disclosed.
Further, Patent Document 2 discloses a liquid detergent composition for filling a pump former container containing an acylamino acid triethanolamine salt and other surfactants.
特許文献１および特許文献２に記載の液体洗浄剤組成物やポンプフォーマー容器充填用液状洗浄剤組成物には、殺菌剤が配合されていないため、皮膚に付着した細菌等への殺菌性能は期待できない。 Since the liquid detergent composition described in Patent Document 1 and Patent Document 2 and the liquid detergent composition for filling a pump former container do not contain a bactericidal agent, the bactericidal performance against bacteria attached to the skin is I can't expect it.
特許文献３には、トリクロサン、イソプロピルメチルフェノール及びパラクロロメタキシレノールからなる群から選ばれる少なくとも１種の殺菌剤、グリセリルエーテル並びにアニオン界面活性剤としてのポリオキシエチレンアルキルエーテル硫酸塩を含む皮膚殺菌洗浄剤組成物が開示されている。
従来、界面活性剤を含む組成物にフェノール系殺菌剤を配合すると、高濃度の界面活性剤中では活性剤ミセル中にフェノール系殺菌剤が取り込まれ、不活化してしまい、殺菌効果が低下する傾向にあることが知られていた。そこで、特許文献３では、組成物の殺菌性能及び安定性を保つために殺菌剤に加え、グリセリルエーテル、アニオン界面活性剤のポリオキシエチレンアルキルエーテル硫酸塩を配合している。
しかし、ポリオキシエチレンアルキルエーテル硫酸塩は、殺菌性能に格別寄与する成分ではなく、このような成分を入れずに優れた殺菌性能を発揮し得る皮膚身体殺菌洗浄剤組成物は得られていなかった。
Patent Document 3 discloses skin sterilization washing comprising at least one fungicide selected from the group consisting of triclosan, isopropylmethylphenol and parachlorometaxylenol, glyceryl ether and polyoxyethylene alkyl ether sulfate as an anionic surfactant. An agent composition is disclosed.
Conventionally, when a phenolic fungicide is blended with a composition containing a surfactant, the phenolic fungicide is incorporated into the activator micelles in a high concentration surfactant, and the fungicidal effect is lowered. It was known that there was a tendency. Therefore, in Patent Document 3, glyceryl ether and an anionic surfactant polyoxyethylene alkyl ether sulfate are blended in addition to the bactericidal agent in order to maintain the bactericidal performance and stability of the composition.
However, polyoxyethylene alkyl ether sulfate is not a component that particularly contributes to bactericidal performance, and no skin body bactericidal cleaning composition that can exhibit excellent bactericidal performance without such components has been obtained. .
本発明は、上記のような課題を解決するためになされたものであり、優れた洗浄殺菌性能を発揮し得る皮膚身体殺菌洗浄剤を提供することを目的とする。 The present invention has been made to solve the above-described problems, and an object of the present invention is to provide a skin body sterilizing and cleaning agent capable of exhibiting excellent cleaning and sterilizing performance.
本発明者らは、上記課題を解決するために鋭意検討した結果、界面活性剤として知られている化合物のうち、脂肪酸アシルグルタミン酸エタノールアミンはフェノール系殺菌剤との相溶性に優れており、高濃度の界面活性剤中においても殺菌効果が低下しにくいことを発見した。そして、脂肪酸アシルグルタミン酸エタノールアミンとフェノール系殺菌剤を混合した場合には可溶化のために必要な成分を配合する必要はないことを見出した。
さらに、フェノール系殺菌剤と脂肪酸アシルグルタミン酸エタノールアミンを混合すると、フェノール系殺菌剤を加えた場合に予想される殺菌性能を超えて優れた殺菌性能を有すること、すなわち、脂肪酸アシルグルタミン酸エタノールアミンにはフェノール系殺菌剤の殺菌作用を促進する作用があることを見出した。その結果、本発明に想到した。
As a result of diligent studies to solve the above problems, the present inventors have found that among the compounds known as surfactants, fatty acid acyl glutamate ethanolamine is excellent in compatibility with phenolic fungicides, It has been found that the bactericidal effect is hardly lowered even in a surfactant having a concentration. And when fatty acid acyl glutamate ethanolamine and a phenol type fungicide were mixed, it discovered that it was not necessary to mix | blend the component required for solubilization.
Furthermore, when a phenolic fungicide and fatty acid acylglutamate ethanolamine are mixed, it has superior bactericidal performance beyond that expected when a phenolic fungicide is added. It has been found that there is an action of promoting the bactericidal action of phenolic fungicides. As a result, the present invention has been conceived.
すなわち、本発明の皮膚身体殺菌洗浄剤組成物は、フェノール系殺菌剤を０．２重量％以上と、
脂肪酸アシルグルタミン酸エタノールアミンを０．１重量％以上とを含み、
ｐＨが５．８以下であることを特徴とする。
That is, the skin body disinfectant cleaning composition of the present invention has a phenolic disinfectant of 0.2% by weight or more,
Containing 0.1% by weight or more of fatty acid acyl glutamate ethanolamine,
The pH is 5.8 or less.
本発明の皮膚身体殺菌洗浄剤組成物は、殺菌剤としてのフェノール系殺菌剤に加え、殺菌性能を促進する脂肪酸アシルグルタミン酸エタノールアミンを含んでいるため優れた洗浄殺菌性能を発揮することができる。この配合であると、可溶化のために必要な成分を配合する必要はないため、製造時の手間が少なく及びコスト面でも有利である。
また、ｐＨを５．８以下とすることによって殺菌力を好適に発揮させることができる。
The skin and body sterilizing and cleaning composition of the present invention can exhibit excellent cleaning and sterilizing performance because it contains a fatty acyl acyl glutamate ethanolamine that promotes sterilizing performance in addition to the phenolic sterilizing agent as a sterilizing agent. With this blending, it is not necessary to blend the components necessary for solubilization, so there is less labor during production and the cost is advantageous.
Moreover, bactericidal power can be suitably exhibited by making pH into 5.8 or less.
本発明の皮膚身体殺菌洗浄剤組成物では、上記脂肪酸アシルグルタミン酸エタノールアミンを２．０重量％以上含むことが望ましい。
脂肪酸アシルグルタミン酸エタノールアミンの配合量が２．０重量％以上であると、組成物が透明液状となるので組成物の均一性の観点及び外観の観点から好ましい。
In the skin body disinfectant cleaning composition of the present invention, it is desirable to contain 2.0% by weight or more of the fatty acid acyl glutamate ethanolamine.
When the blending amount of the fatty acid acylglutamate ethanolamine is 2.0% by weight or more, the composition becomes a transparent liquid, which is preferable from the viewpoint of the uniformity of the composition and the appearance.
本発明の皮膚身体殺菌洗浄剤組成物では、上記脂肪酸アシルグルタミン酸エタノールアミンを２５．０重量％以下含むことが望ましい。
脂肪酸アシルグルタミン酸エタノールアミンは、殺菌促進作用があるものの、多く配合しすぎると殺菌力が低下する傾向があるため、配合量が２５．０重量％以下であることが好ましい。
In the skin body disinfectant cleaning composition of the present invention, it is desirable to contain 25.0% by weight or less of the fatty acid acyl glutamate ethanolamine.
Although fatty acid acylglutamate ethanolamine has a sterilization promoting effect, if it is added too much, the sterilizing power tends to be reduced, so that the blending amount is preferably 25.0% by weight or less.
本発明の皮膚身体殺菌洗浄剤組成物では、上記フェノール系殺菌剤は、トリクロサン及びイソプロピルメチルフェノールからなる群から選択された少なくとも１種であることが望ましい。
また、本発明の皮膚身体殺菌洗浄剤組成物では、上記脂肪酸アシルグルタミン酸エタノールアミンは、ヤシ油脂肪酸アシルグルタミン酸トリエタノールアミン及びラウロイルグルタミン酸トリエタノールアミンからなる群から選択された少なくとも１種であることが望ましい。
In the skin body disinfectant cleaning composition of the present invention, the phenolic disinfectant is preferably at least one selected from the group consisting of triclosan and isopropylmethylphenol.
In the skin body disinfecting and cleaning composition of the present invention, the fatty acid acyl glutamate ethanolamine is at least one selected from the group consisting of coconut oil fatty acid acyl glutamate triethanolamine and lauroyl glutamate triethanolamine. desirable.
本発明の皮膚身体殺菌洗浄剤組成物は、優れた洗浄殺菌性能を発揮することができる。 The skin body sterilizing detergent composition of the present invention can exhibit excellent cleaning and sterilizing performance.
本発明の皮膚身体殺菌洗浄剤組成物は、フェノール系殺菌剤を０．２重量％以上と、
脂肪酸アシルグルタミン酸エタノールアミンを０．１重量％以上とを含み、
ｐＨが５．８以下であることを特徴とする。
なお、本明細書中における各成分の配合比（重量％）は純分基準である。
The skin body disinfectant cleaning composition of the present invention comprises 0.2% by weight or more of phenolic disinfectant,
Containing 0.1% by weight or more of fatty acid acyl glutamate ethanolamine,
The pH is 5.8 or less.
In addition, the compounding ratio (weight%) of each component in this specification is a pure part basis.
フェノール系殺菌剤としては、イソプロピルメチルフェノール（３−メチル−４−イソプロピルフェノール、５−メチル−２−イソプロピルメチルフェノール（チモール）、２−メチル−５−イソプロピルメチルフェノール（カルバクロール）等）、トリクロサン、トリクロロカルバニリド、トリクロロヒドロキシジフェニルエーテル、パラクロロキシレノール、オルトクロロフェノール（２−クロロフェノール）等が挙げられる。
フェノール系殺菌剤は、これらのうち１種を単独で用いてもよく、２種以上を組み合わせて用いてもよい。
これらのフェノール系殺菌剤の中では、イソプロピルメチルフェノール又はトリクロサンが望ましい。
Examples of phenolic fungicides include isopropylmethylphenol (3-methyl-4-isopropylphenol, 5-methyl-2-isopropylmethylphenol (thymol), 2-methyl-5-isopropylmethylphenol (carbachlor), etc.), triclosan , Trichlorocarbanilide, trichlorohydroxydiphenyl ether, parachloroxylenol, orthochlorophenol (2-chlorophenol) and the like.
One of these phenolic fungicides may be used alone, or two or more may be used in combination.
Of these phenolic fungicides, isopropylmethylphenol or triclosan is desirable.
フェノール系殺菌剤の配合量は０．２重量％以上である。フェノール系殺菌剤を０．２重量％以上含むことによって、洗浄殺菌性能が好適に発揮される。
フェノール系殺菌剤の配合量は０．３重量％以上であることが望ましく、０．４重量％以上であることがより望ましい。
また、フェノール系殺菌剤の配合量は２．０重量％以下であることが望ましく、１．０重量％以下であることがより望ましい。
フェノール系殺菌剤の配合量を２．０重量％を超えて配合しても、殺菌力がそれ以上向上しないため望ましくない。また、フェノール系殺菌剤の配合量を２．０重量％を超えて配合すると溶液が白濁化することがある。
なお、フェノール系殺菌剤を２種以上組み合わせて用いる場合のフェノール系殺菌剤の配合量は２種以上のフェノール系殺菌剤の合計量として定める。
The compounding quantity of a phenol type fungicide is 0.2 weight% or more. By including 0.2% by weight or more of the phenol-based disinfectant, the cleaning and disinfecting performance is suitably exhibited.
The blending amount of the phenolic fungicide is preferably 0.3% by weight or more, and more preferably 0.4% by weight or more.
The blending amount of the phenolic fungicide is desirably 2.0% by weight or less, and more desirably 1.0% by weight or less.
Even if the blending amount of the phenolic disinfectant exceeds 2.0% by weight, the disinfecting power is not further improved, which is not desirable. Moreover, when the compounding quantity of a phenol type disinfectant exceeds 2.0 weight%, a solution may become cloudy.
In addition, the blending amount of the phenolic fungicide when two or more phenolic fungicides are used in combination is determined as the total amount of the two or more phenolic fungicides.
脂肪酸アシルグルタミン酸エタノールアミンは、脂肪酸アシルグルタミン酸とエタノールアミンの塩である。
塩がエタノールアミン塩であることが、本願発明の効果を発揮するためには必要であり、ナトリウム塩やカリウム塩では本願発明の効果が好適に発揮されない。
脂肪酸アシルグルタミン酸としては、ヤシ油脂肪酸アシルグルタミン酸（Ｎ−ヤシ油脂肪酸アシル−Ｌ−グルタミン酸）、ラウロイルグルタミン酸（Ｎ−ラウロイル−Ｌ−グルタミン酸）、Ｎ−ミリストイル−Ｌ−グルタミン酸、Ｎ−ステアロイル−Ｌ−グルタミン酸、パーム脂肪酸グルタミン酸が挙げられる。これらの中では、ヤシ油脂肪酸アシルグルタミン酸又はラウロイルグルタミン酸が望ましい。
エタノールアミンとしては、モノエタノールアミン、ジエタノールアミン、及び、トリエタノールアミンが挙げられるが、これらの中ではトリエタノールアミンが望ましい。
上記脂肪酸アシルグルタミン酸とエタノールアミンからなる、脂肪酸アシルグルタミン酸エタノールアミンとしては、ヤシ油脂肪酸アシルグルタミン酸モノエタノールアミン、ヤシ油脂肪酸アシルグルタミン酸ジエタノールアミン、ヤシ油脂肪酸アシルグルタミン酸トリエタノールアミン、ラウロイルグルタミン酸モノエタノールアミン、ラウロイルグルタミン酸ジエタノールアミン、ラウロイルグルタミン酸トリエタノールアミン、Ｎ−ミリストイル−Ｌ−グルタミン酸モノエタノールアミン、Ｎ−ミリストイル−Ｌ−グルタミン酸ジエタノールアミン、Ｎ−ミリストイル−Ｌ−グルタミン酸トリエタノールアミン、Ｎ−ステアロイル−Ｌ−グルタミン酸モノエタノールアミン、Ｎ−ステアロイル−Ｌ−グルタミン酸ジエタノールアミン、Ｎ−ステアロイル−Ｌ−グルタミン酸トリエタノールアミン、パーム脂肪酸グルタミン酸モノエタノールアミン、パーム脂肪酸グルタミン酸ジエタノールアミン、パーム脂肪酸グルタミン酸トリエタノールアミンが挙げられ、これらの中ではヤシ油脂肪酸アシルグルタミン酸トリエタノールアミン又はラウロイルグルタミン酸トリエタノールアミンであることが望ましい。
脂肪酸アシルグルタミン酸エタノールアミンは、これらのうち１種を単独で用いてもよく、２種以上を組み合わせて用いてもよい。
Fatty acid acyl glutamate ethanolamine is a salt of fatty acyl glutamate and ethanolamine.
It is necessary for the salt to be an ethanolamine salt in order to exhibit the effects of the present invention, and sodium salts and potassium salts do not exhibit the effects of the present invention suitably.
Examples of fatty acid acylglutamic acid include coconut oil fatty acid acylglutamic acid (N-coconut oil fatty acid acyl-L-glutamic acid), lauroylglutamic acid (N-lauroyl-L-glutamic acid), N-myristoyl-L-glutamic acid, N-stearoyl-L- Examples include glutamic acid and palm fatty acid glutamic acid. Among these, palm oil fatty acid acyl glutamic acid or lauroyl glutamic acid is desirable.
Examples of ethanolamine include monoethanolamine, diethanolamine, and triethanolamine, among which triethanolamine is desirable.
The fatty acid acyl glutamic acid ethanolamine consisting of the above fatty acid acyl glutamic acid and ethanolamine includes coconut oil fatty acid acyl glutamic acid monoethanolamine, coconut oil fatty acid acyl glutamic acid diethanolamine, coconut oil fatty acid acyl glutamic acid triethanolamine, lauroyl glutamic acid monoethanolamine, lauroyl Glutamate diethanolamine, lauroylglutamate triethanolamine, N-myristoyl-L-glutamate monoethanolamine, N-myristoyl-L-glutamate diethanolamine, N-myristoyl-L-glutamate triethanolamine, N-stearoyl-L-glutamate monoethanolamine N-stearoyl-L-glutamic acid diethanolamine, -Stearoyl-L-glutamic acid triethanolamine, palm fatty acid glutamic acid monoethanolamine, palm fatty acid glutamic acid diethanolamine, palm fatty acid glutamic acid triethanolamine, among them coconut oil fatty acid acyl glutamic acid triethanolamine or lauroyl glutamic acid triethanolamine It is desirable that
One of these fatty acid acylglutamate ethanolamines may be used alone, or two or more thereof may be used in combination.
脂肪酸アシルグルタミン酸エタノールアミンの配合量は０．１重量％以上である。脂肪酸アシルグルタミン酸エタノールアミンを０．１重量％以上含むことによって、脂肪酸アシルグルタミン酸エタノールアミンによる殺菌促進性能が好適に発揮される。
脂肪酸アシルグルタミン酸エタノールアミンの配合量は１．０重量％以上であることが望ましく、２．０重量％以上であることがより望ましい。
脂肪酸アシルグルタミン酸エタノールアミンの配合量が１．０重量％以上であると、組成物中に沈殿が発生することが防止されるため好ましく、２．０重量％以上であると、組成物が透明液状となるので組成物の均一性の観点及び外観の観点からより好ましい。
また、脂肪酸アシルグルタミン酸エタノールアミンの配合量は２５．０重量％以下であることが望ましく、２０．０重量％以下であることがより望ましい。
なお、脂肪酸アシルグルタミン酸エタノールアミンを２種以上組み合わせて用いる場合の脂肪酸アシルグルタミン酸エタノールアミンの配合量は２種以上の脂肪酸アシルグルタミン酸エタノールアミンの合計量として定める。
The amount of fatty acid acyl glutamate ethanolamine is 0.1% by weight or more. By containing 0.1% by weight or more of fatty acid acyl glutamate ethanolamine, the sterilization promoting performance by fatty acid acyl glutamate ethanolamine is suitably exhibited.
The amount of fatty acid acylglutamate ethanolamine is desirably 1.0% by weight or more, and more desirably 2.0% by weight or more.
When the amount of fatty acid acylglutamate ethanolamine is 1.0% by weight or more, precipitation is prevented from occurring in the composition, and when it is 2.0% by weight or more, the composition is a transparent liquid. Therefore, it is more preferable from the viewpoint of the uniformity of the composition and the viewpoint of the appearance.
The blending amount of fatty acid acyl glutamate ethanolamine is preferably 25.0% by weight or less, and more preferably 20.0% by weight or less.
In addition, the blending amount of the fatty acid acyl glutamate ethanolamine when two or more fatty acid acyl glutamate ethanolamines are used in combination is determined as the total amount of the two or more fatty acyl acyl glutamate ethanolamines.
本発明の皮膚身体殺菌洗浄剤組成物は、ｐＨが５．８以下となっている。ｐＨが５．８以下であると殺菌力が好適に発揮される。ｐＨは５．５以下であることがより好ましく、５．０以下であることがさらに好ましい。
ｐＨの下限値は特に限定されるものではないが、皮膚身体殺菌洗浄剤組成物が身体に付着した際の安全性を考慮すると、ｐＨが３．０以上であることが好ましく、４．０以上であることがより好ましい。
The skin body disinfectant cleaning composition of the present invention has a pH of 5.8 or less. When the pH is 5.8 or less, the bactericidal power is suitably exhibited. The pH is more preferably 5.5 or less, and further preferably 5.0 or less.
The lower limit of the pH is not particularly limited, but considering the safety when the skin body disinfectant cleaning composition adheres to the body, the pH is preferably 3.0 or more, and 4.0 or more. It is more preferable that
本発明の皮膚身体殺菌洗浄剤組成物には、ｐＨを好適な範囲に調整するためにｐＨ調整剤が含まれていてもよい。ｐＨ調整剤の例としては、酢酸、クエン酸、リンゴ酸、乳酸、水酸化ナトリウム、水酸化カリウム、有機アミン類等が挙げられる。
これらは、単独で用いても、２種以上を組み合わせて用いてもよい。
The skin body disinfectant cleaning composition of the present invention may contain a pH adjuster in order to adjust the pH to a suitable range. Examples of pH adjusters include acetic acid, citric acid, malic acid, lactic acid, sodium hydroxide, potassium hydroxide, organic amines and the like.
These may be used alone or in combination of two or more.
また、本発明の皮膚身体殺菌洗浄剤組成物には、溶剤が含まれていてもよい。溶剤としては、エタノール、イソプロパノール、ｎ−プロパノールなどの低級アルコール類、プロピレングリコール、グリセリン、ジグリセリン、１，３−ブチレングリコール、ジプロピレングリコール、などの多価アルコール類を用いることができる。
これらは、単独で用いても、２種以上を組み合わせて用いてもよい。
溶剤が含まれる場合、その配合量は１〜１０重量％であることが望ましく、３〜７重量％であることがより望ましい。
Moreover, the skin body disinfection cleaning composition of this invention may contain the solvent. As the solvent, polyhydric alcohols such as lower alcohols such as ethanol, isopropanol, and n-propanol, propylene glycol, glycerin, diglycerin, 1,3-butylene glycol, and dipropylene glycol can be used.
These may be used alone or in combination of two or more.
When a solvent is included, the blending amount is desirably 1 to 10% by weight, and more desirably 3 to 7% by weight.
本発明の皮膚身体殺菌洗浄剤組成物には、残部としての水が含まれる。水としては水道水、蒸留水、精製水又はイオン交換水等が挙げられる。これらは、単独で用いても、２種以上を組み合わせて用いてもよい。特に、不純物の少なさ及び経済性の点から精製水であることが望ましい。 The skin body disinfectant cleaning composition of the present invention contains water as the balance. Examples of water include tap water, distilled water, purified water, and ion exchange water. These may be used alone or in combination of two or more. In particular, purified water is desirable from the viewpoint of few impurities and economical efficiency.
本発明の皮膚身体殺菌洗浄剤組成物には、皮膚身体用の殺菌洗浄剤組成物に含まれてもよい他の成分として、脂肪酸アシルグルタミン酸エタノールアミン以外の界面活性剤、保湿剤、増粘剤、キレート剤、薬効成分、防腐剤、色素、顔料、紫外線吸収剤、抗酸化剤、香料、染料などを適宜配合することができる。 In the skin body sterilizing and cleaning composition of the present invention, as other components that may be included in the skin and body sterilizing and cleaning composition, surfactants other than fatty acid acylglutamic acid ethanolamine, moisturizing agents, thickeners Chelating agents, medicinal ingredients, preservatives, pigments, pigments, ultraviolet absorbers, antioxidants, fragrances, dyes, and the like can be appropriately blended.
本発明の皮膚身体殺菌洗浄剤組成物は、常法に従って製造することができる。例えば、皮膚身体殺菌洗浄剤組成物を構成する各成分を適宜混合し、ミキサーを用いて攪拌することにより製造することができる。 The skin body disinfectant cleaning composition of the present invention can be produced according to a conventional method. For example, it can manufacture by mixing each component which comprises a skin body disinfection cleaning composition suitably, and stirring using a mixer.
本発明の皮膚身体殺菌洗浄剤組成物は、皮膚身体用の殺菌洗浄剤組成物として用いられるものであり、ハンドソープ等の手指用の殺菌洗浄剤として用いられることが望ましい。その他、ボディシャンプー、ヘアーシャンプー、洗顔料等として用いることもできる。 The skin body sterilizing detergent composition of the present invention is used as a sterilizing detergent composition for skin body, and is desirably used as a sterilizing detergent for fingers such as hand soap. In addition, it can also be used as a body shampoo, hair shampoo, face wash, and the like.
本発明の皮膚身体殺菌洗浄剤組成物は、例えば、ポンプフォーマー容器に充填されて手指洗浄に用いることができる。
例えば、ポンプフォーマーから皮膚身体殺菌洗浄剤組成物を発泡させて吐出させ、手指に皮膚身体殺菌洗浄剤組成物をすり込むようにして３０〜６０秒ほど手指洗浄を行ったのちに水で洗い流すことで、手指の殺菌を好適に行うことができる。
特に、外食産業の厨房、洗面所、食品加工工場、介護施設、病院等において用いられることが望ましい。
The skin / body disinfectant cleaning composition of the present invention can be used, for example, for hand washing after being filled in a pump former container.
For example, the skin body sterilizing detergent composition is foamed and discharged from a pump former, and the skin body sterilizing detergent composition is rubbed into the fingers and washed for 30 to 60 seconds, and then rinsed with water. Thus, sterilization of fingers can be suitably performed.
In particular, it is preferably used in kitchens, washrooms, food processing factories, nursing homes, hospitals, etc. in the restaurant industry.
本発明の皮膚身体殺菌洗浄剤組成物を使用して殺菌可能な菌としては、例えば、大腸菌（Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ）、黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）、緑膿菌、サルモネラ菌等が挙げられ、本発明の皮膚身体殺菌洗浄剤組成物はこれらの菌の殺菌用途に好適に用いることができる。 Examples of the bacteria that can be sterilized using the skin body disinfectant cleaning composition of the present invention include Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella, and the like. The skin body disinfectant cleaning composition can be suitably used for disinfecting these bacteria.
以下に本発明をより具体的に説明する実施例を示すが、本発明はこれらの実施例に限定されるものではない。以下、特に明記のない限り％は重量％を意味する。
（実施例１〜１０、比較例１〜７）
表１、２に示す成分を水に順次加え、撹拌することによって、表１及び表２に示す組成からなる皮膚身体殺菌洗浄剤組成物を調製した。
各成分の配合量は、ｐＨ調整剤以外の成分の配合量の合計を１００％として示した。
また、各成分の配合量は純分表示である。
ｐＨ調整剤は、各実施例及び比較例に示すｐＨになるような量を加えた。その量を「適量」と示している。
Examples for more specifically explaining the present invention are shown below, but the present invention is not limited to these examples. Hereinafter, “%” means “wt%” unless otherwise specified.
(Examples 1-10, Comparative Examples 1-7)
The components shown in Tables 1 and 2 were sequentially added to water and stirred to prepare skin body disinfectant cleaning compositions having the compositions shown in Tables 1 and 2.
The blending amount of each component is shown as 100% of the total blending amount of components other than the pH adjuster.
Moreover, the compounding quantity of each component is a pure part display.
The pH adjusting agent was added in such an amount that the pH shown in each example and comparative example was obtained. The amount is indicated as “appropriate amount”.
（組成物外観）
調製した皮膚身体殺菌洗浄剤組成物の外観を目視観察した。実施例３の組成物では組成物が白濁しており、実施例４の組成物では白濁に加え沈殿の発生が見られた。
これらの組成物は脂肪酸アシルグルタミン酸エタノールアミンの配合量がそれぞれ１．００％、０．１０％と低いため、組成物が透明液状にはならなかったものと推測される。
また、実施例６の組成物でも白濁が見られた。これは、トリクロサン、イソプロピルメチルフェノールの配合量が合計で２．０％と多かったためと推測される。
(Composition appearance)
The appearance of the prepared skin body disinfectant cleaning composition was visually observed. In the composition of Example 3, the composition was cloudy, and in the composition of Example 4, precipitation was observed in addition to cloudiness.
Since these compositions have low amounts of fatty acid acylglutamate ethanolamine of 1.00% and 0.10%, respectively, it is presumed that the composition did not become a transparent liquid.
Further, white turbidity was also observed in the composition of Example 6. This is presumably because the total amount of triclosan and isopropylmethylphenol was 2.0%.
（殺菌力試験）
菌株として、大腸菌（Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ）ＮＢＲＣ３９７２、黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）ＮＢＲＣ１２７３２、緑膿菌（Ｐｓｅｕｄｏｍｏｎａｓ ａｅｒｕｇｉｎｏｓａ）ＮＢＲＣ１３２７５、サルモネラ菌（Ｓａｌｍｏｎｅｌｌａ ｅｎｔｅｒｉｔｉｄｉｓ）ＮＢＲＣ３３１３を準備した。
各菌株を普通ブイヨン培地で３５℃、２４時間振とう培養して、１０８〜１０９ｃｆｕ／ｍＬの試験菌液をそれぞれ調製した。
各実施例及び比較例で調製した皮膚身体殺菌洗浄剤組成物１０ｍＬに、試験菌液０．１ｍＬを加え、混合後、室温で３０秒又は６０秒作用させた。
その後、混合液をＳＣＤＬＰ培地に１白金耳移植し、３５℃、４８時間培養後、菌の有無を判定した。
表１及び２には、菌ありの場合を「＋」、菌なしの場合を「−」と示した。
(Bactericidal test)
As strains, Escherichia coli NBRC 3972, Staphylococcus aureus NBRC12732, Pseudomonas aeruginosa NBRC13275, and Salmonella enteriti33 BRC were prepared.
Each strain was cultured with shaking in a normal broth medium at 35 ° C. for 24 hours to prepare 10 8 to 10 9 cfu / mL test bacterial solutions, respectively.
0.1 mL of the test bacterial solution was added to 10 mL of the skin / body disinfectant cleaning composition prepared in each Example and Comparative Example, and after mixing, the mixture was allowed to act at room temperature for 30 seconds or 60 seconds.
Thereafter, one platinum loop of the mixed solution was transplanted into the SCDLP medium, and after culturing at 35 ° C. for 48 hours, the presence or absence of bacteria was determined.
In Tables 1 and 2, “+” indicates the presence of bacteria and “−” indicates the absence of bacteria.
殺菌力試験の結果、各実施例に係る皮膚身体殺菌洗浄剤組成物を用いた場合、大腸菌、黄色ブドウ球菌、緑膿菌及びサルモネラ菌に対し、６０秒の作用時間で殺菌作用があることがわかった。また、多くの実施例において３０秒の作用時間でも殺菌作用が発揮されていることも分かった。
実施例１〜１０のうち、ｐＨが５．５とやや高い実施例８は殺菌作用が弱めであり、ｐＨが５．０付近又はそれ以下であると殺菌作用がより強く発揮されることもわかった。
一方、各比較例に係る皮膚身体殺菌洗浄剤組成物を用いた場合、殺菌作用が発揮されておらず、とくに大腸菌、緑膿菌及びサルモネラ菌に対しての殺菌作用は観察されなかった。黄色ブドウ球菌についても３０秒で殺菌作用が発揮されている例はなかった。
これは、フェノール系殺菌剤が含まれていない（比較例１）、脂肪酸アシルグルタミン酸の塩がエタノールアミン塩でなくナトリウム塩又はカリウム塩（比較例２、３）、フェノール系殺菌剤の量が少ない（比較例４、５）、ｐＨが高い（比較例６、７）といったように、各比較例に係る皮膚身体殺菌洗浄剤組成物が本願発明の構成の一部を満たさないことに起因していると考えられる。
As a result of the bactericidal activity test, it was found that when the skin body disinfectant cleaning composition according to each example was used, it had bactericidal action against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella in 60 seconds. It was. Moreover, it turned out that the bactericidal action is exhibited in the working time of 30 second in many Examples.
Among Examples 1 to 10, Example 8 having a slightly high pH of 5.5 is weak in bactericidal action, and it is also found that bactericidal action is more strongly exhibited when pH is around 5.0 or lower. It was.
On the other hand, when the skin / body sterilizing detergent composition according to each comparative example was used, the bactericidal action was not exhibited, and particularly the bactericidal action against Escherichia coli, Pseudomonas aeruginosa and Salmonella was not observed. As for Staphylococcus aureus, there was no example in which the bactericidal action was exhibited in 30 seconds.
This does not contain a phenolic fungicide (Comparative Example 1), the fatty acid acylglutamic acid salt is not an ethanolamine salt but a sodium salt or potassium salt (Comparative Examples 2 and 3), and the amount of the phenolic fungicide is small (Comparative Examples 4 and 5), such as high pH (Comparative Examples 6 and 7), because the skin body disinfectant cleaning composition according to each Comparative Example does not satisfy a part of the configuration of the present invention. It is thought that there is.
Claims (5)
脂肪酸アシルグルタミン酸エタノールアミンを０．１重量％以上とを含み、
ｐＨが５．８以下であることを特徴とする皮膚身体殺菌洗浄剤組成物。 0.2% by weight or more of phenolic fungicide,
Containing 0.1% by weight or more of fatty acid acyl glutamate ethanolamine,
A skin body disinfectant cleaning composition having a pH of 5.8 or less.
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