JP2013250218A - 自動分析装置 - Google Patents
自動分析装置 Download PDFInfo
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- JP2013250218A JP2013250218A JP2012126668A JP2012126668A JP2013250218A JP 2013250218 A JP2013250218 A JP 2013250218A JP 2012126668 A JP2012126668 A JP 2012126668A JP 2012126668 A JP2012126668 A JP 2012126668A JP 2013250218 A JP2013250218 A JP 2013250218A
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- 238000001514 detection method Methods 0.000 claims abstract description 12
- 239000003153 chemical reaction reagent Substances 0.000 claims description 25
- 230000007723 transport mechanism Effects 0.000 claims description 24
- 238000009434 installation Methods 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 4
- 230000002159 abnormal effect Effects 0.000 claims description 3
- 230000001678 irradiating effect Effects 0.000 claims description 3
- 230000032258 transport Effects 0.000 claims description 3
- 230000007246 mechanism Effects 0.000 abstract description 12
- 239000000523 sample Substances 0.000 description 24
- 238000005259 measurement Methods 0.000 description 11
- 230000023555 blood coagulation Effects 0.000 description 10
- 230000004520 agglutination Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- 230000005856 abnormality Effects 0.000 description 6
- 238000005070 sampling Methods 0.000 description 6
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 238000012790 confirmation Methods 0.000 description 4
- 230000006866 deterioration Effects 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000004044 response Effects 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
- G01N15/075—Investigating concentration of particle suspensions by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/15—Preventing contamination of the components of the optical system or obstruction of the light path
- G01N2021/155—Monitoring cleanness of window, lens, or other parts
- G01N2021/157—Monitoring by optical means
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
- G01N2021/825—Agglutination
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0439—Rotary sample carriers, i.e. carousels
- G01N2035/0441—Rotary sample carriers, i.e. carousels for samples
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0439—Rotary sample carriers, i.e. carousels
- G01N2035/0443—Rotary sample carriers, i.e. carousels for reagents
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/02—Mechanical
- G01N2201/025—Mechanical control of operations
- G01N2201/0256—Sensor for insertion of sample, cuvette, test strip
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/04—Batch operation; multisample devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/04—Batch operation; multisample devices
- G01N2201/0415—Carrusel, sequential
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/061—Sources
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/12—Circuits of general importance; Signal processing
- G01N2201/127—Calibration; base line adjustment; drift compensation
- G01N2201/12723—Self check capacity; automatic, periodic step of checking
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- Robotics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Plasma & Fusion (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
【解決手段】複数の検出部で共通に用いられる反応容器搬送機構117に、光源光量チェック用検出器130を設け、この検出器130で光源124の光量チェックを行う。
【選択図】 図2
Description
102 サンプリングアーム
103 サンプル分注プローブ
104 サンプルディスク
105 サンプル容器
106 反応容器
107 サンプル用シリンジポンプ
108 試薬分注機構
109 試薬分注アーム
110 試薬分注プローブ
111 試薬ディスク
112 試薬容器
113 試薬昇温機構
114 試薬用シリンジポンプ
115 反応容器供給部
116 反応容器廃棄部
117 反応容器搬送機構
118 反応容器保持部
119 検出部
120 反応容器設置部
121 キーボード
122 CRT
123 コンピュータ(制御部)
124 光源
125 検出器
126 A/D変換器
127 インターフェイス
128 プリンタ
129 メモリ
130 光源光量チェック用検知器
131 補助具
Claims (5)
- 試料と試薬とを反応させる反応容器を載置する反応容器設置部を備えた、複数の検出部と、
前記反応容器設置部の底部に設けられた、光を照射する光源と、
前記反応容器設置部に設けられ、前記光源から照射された光の前記反応容器からの散乱光を検出する第1検出器と、
前記反応容器を把持して、前記反応容器の搬送及び設置を行う、前記複数の検出部に共通の反応容器搬送機構と、
前記反応容器搬送機構に設けられ、前記光源から照射する光を検出する第2検出器と、を備えることを特徴とする自動分析装置。 - 請求項1記載の自動分析装置において、
前記第2検出器の検出光量が予め設定された閾値に満たない場合には、前記光源の光量が不足している旨の、または、前記光源の交換を促すアラームを発信する制御部を備えることを特徴とする自動分析装置。 - 請求項1または2記載の自動分析装置において、
前記光源から照射する光を検出でき、かつ、外部からの光を遮蔽する素材および形状の補助具と、を備え、
前記補助具は、前記反応容器搬送機構に把持され、前記光源の上方に搬送され、外部からの光を遮蔽した状態で、前記光源から照射された光を前記第2検出器により検出することを特徴とする自動分析装置。 - 請求項1〜3のいずれか記載の自動分析装置において、
前記反応容器設置部に、空の反応容器が載置され、
前記空の反応容器を透過した光における前記第2検出器の検出光量が、予め設定された第2閾値に満たない場合には、前記空の反応容器に異常がある旨のアラームを発信することを特徴とする自動分析装置。 - 請求項1〜4のいずれか記載の自動分析装置において、
前記第2検出器の検出光量に基づき、前記反応容器搬送機構の水平方向の駆動を停止させることを特徴とする自動分析装置。
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012126668A JP5953129B2 (ja) | 2012-06-04 | 2012-06-04 | 自動分析装置 |
CN201380027466.4A CN104335051B (zh) | 2012-06-04 | 2013-05-24 | 自动分析装置 |
US14/402,416 US9506940B2 (en) | 2012-06-04 | 2013-05-24 | Automatic analysis apparatus |
EP13800133.4A EP2857845B1 (en) | 2012-06-04 | 2013-05-24 | Automatic analysis device |
PCT/JP2013/064427 WO2013183459A1 (ja) | 2012-06-04 | 2013-05-24 | 自動分析装置 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012126668A JP5953129B2 (ja) | 2012-06-04 | 2012-06-04 | 自動分析装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013250218A true JP2013250218A (ja) | 2013-12-12 |
JP5953129B2 JP5953129B2 (ja) | 2016-07-20 |
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Application Number | Title | Priority Date | Filing Date |
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JP2012126668A Active JP5953129B2 (ja) | 2012-06-04 | 2012-06-04 | 自動分析装置 |
Country Status (5)
Country | Link |
---|---|
US (1) | US9506940B2 (ja) |
EP (1) | EP2857845B1 (ja) |
JP (1) | JP5953129B2 (ja) |
CN (1) | CN104335051B (ja) |
WO (1) | WO2013183459A1 (ja) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016017289A1 (ja) * | 2014-07-29 | 2016-02-04 | 株式会社 日立ハイテクノロジーズ | 自動分析装置 |
WO2017047240A1 (ja) * | 2015-09-17 | 2017-03-23 | 株式会社 日立ハイテクノロジーズ | 自動分析装置 |
CN111175240A (zh) * | 2014-05-30 | 2020-05-19 | 株式会社日立高新技术 | 自动分析装置 |
US10753870B2 (en) | 2016-09-14 | 2020-08-25 | Hitachi High-Tech Corporation | Automatic analysis apparatus including a reaction container holding part having a surface that reflects light emitted from a light source |
US11971295B2 (en) | 2020-09-30 | 2024-04-30 | Canon Medical Systems Corporation | Automatic analyzing apparatus and jig |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6208356B2 (ja) * | 2014-07-07 | 2017-10-04 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
WO2016136377A1 (ja) * | 2015-02-25 | 2016-09-01 | 株式会社 日立ハイテクノロジーズ | 自動分析装置 |
JP1574656S (ja) | 2016-09-29 | 2018-10-09 | ||
JP1574655S (ja) | 2016-09-29 | 2018-10-09 | ||
CN111201440B (zh) * | 2017-10-10 | 2021-04-20 | 株式会社日立高新技术 | 自动分析装置 |
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2012
- 2012-06-04 JP JP2012126668A patent/JP5953129B2/ja active Active
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2013
- 2013-05-24 EP EP13800133.4A patent/EP2857845B1/en active Active
- 2013-05-24 US US14/402,416 patent/US9506940B2/en active Active
- 2013-05-24 CN CN201380027466.4A patent/CN104335051B/zh active Active
- 2013-05-24 WO PCT/JP2013/064427 patent/WO2013183459A1/ja active Application Filing
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Cited By (9)
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CN111175240A (zh) * | 2014-05-30 | 2020-05-19 | 株式会社日立高新技术 | 自动分析装置 |
WO2016017289A1 (ja) * | 2014-07-29 | 2016-02-04 | 株式会社 日立ハイテクノロジーズ | 自動分析装置 |
JPWO2016017289A1 (ja) * | 2014-07-29 | 2017-04-27 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
CN106662593A (zh) * | 2014-07-29 | 2017-05-10 | 株式会社日立高新技术 | 自动分析装置 |
US10267817B2 (en) | 2014-07-29 | 2019-04-23 | Hitachi High-Technologies Corporation | Automatic analysis apparatus |
WO2017047240A1 (ja) * | 2015-09-17 | 2017-03-23 | 株式会社 日立ハイテクノロジーズ | 自動分析装置 |
JPWO2017047240A1 (ja) * | 2015-09-17 | 2018-07-05 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
US10753870B2 (en) | 2016-09-14 | 2020-08-25 | Hitachi High-Tech Corporation | Automatic analysis apparatus including a reaction container holding part having a surface that reflects light emitted from a light source |
US11971295B2 (en) | 2020-09-30 | 2024-04-30 | Canon Medical Systems Corporation | Automatic analyzing apparatus and jig |
Also Published As
Publication number | Publication date |
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US20150147230A1 (en) | 2015-05-28 |
CN104335051A (zh) | 2015-02-04 |
EP2857845B1 (en) | 2019-08-14 |
EP2857845A4 (en) | 2016-02-10 |
WO2013183459A1 (ja) | 2013-12-12 |
JP5953129B2 (ja) | 2016-07-20 |
EP2857845A1 (en) | 2015-04-08 |
US9506940B2 (en) | 2016-11-29 |
CN104335051B (zh) | 2016-03-02 |
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