JP2007223952A5 - - Google Patents

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Publication number
JP2007223952A5
JP2007223952A5 JP2006047064A JP2006047064A JP2007223952A5 JP 2007223952 A5 JP2007223952 A5 JP 2007223952A5 JP 2006047064 A JP2006047064 A JP 2006047064A JP 2006047064 A JP2006047064 A JP 2006047064A JP 2007223952 A5 JP2007223952 A5 JP 2007223952A5
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JP
Japan
Prior art keywords
diagnostic imaging
dvr
composition
image
lobe
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Pending
Application number
JP2006047064A
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English (en)
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JP2007223952A (ja
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Priority to JP2006047064A priority Critical patent/JP2007223952A/ja
Priority claimed from JP2006047064A external-priority patent/JP2007223952A/ja
Publication of JP2007223952A publication Critical patent/JP2007223952A/ja
Publication of JP2007223952A5 publication Critical patent/JP2007223952A5/ja
Pending legal-status Critical Current

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Claims (3)

  1. 陽電子放出核種にて標識されたBF−227(6−[2−(フルオロ)エトキシ]−2−[2−(2−ジメチルアミノチアゾール−5−イル)エテニル]ベンゾキサゾール)をプローブとして含む、ヒト対象におけるアミロイドβ蛋白が蓄積する疾患の画像診断用組成物であって、対象に静脈内投与され、PET装置および脳MRI装置と併用され、DVR計算値もしくは計算画像およびSUV画像が得られることを特徴とする、画像診断用組成物。
  2. Logan DVR法を用いて脳領域のDVR計算画像が得られ、小脳皮質領域を基準として前頭葉、側頭葉および頭頂葉におけるLogan DVRの閾値を1.1とすることを特徴とする請求項1記載の画像診断用組成物。
  3. 陽電子放出核種が11Cである、請求項1または2のいずれか1項記載の画像診断用組成物。
JP2006047064A 2006-02-23 2006-02-23 アミロイドβ蛋白が蓄積する疾患の画像診断プローブ Pending JP2007223952A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2006047064A JP2007223952A (ja) 2006-02-23 2006-02-23 アミロイドβ蛋白が蓄積する疾患の画像診断プローブ

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006047064A JP2007223952A (ja) 2006-02-23 2006-02-23 アミロイドβ蛋白が蓄積する疾患の画像診断プローブ

Publications (2)

Publication Number Publication Date
JP2007223952A JP2007223952A (ja) 2007-09-06
JP2007223952A5 true JP2007223952A5 (ja) 2008-01-17

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JP2006047064A Pending JP2007223952A (ja) 2006-02-23 2006-02-23 アミロイドβ蛋白が蓄積する疾患の画像診断プローブ

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JP (1) JP2007223952A (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5190893B2 (ja) * 2006-12-25 2013-04-24 国立大学法人東北大学 ベンゾキサゾール誘導体
US8932557B2 (en) 2008-02-14 2015-01-13 Eli Lilly And Company Imaging agents for detecting neurological dysfunction
PL2247558T3 (pl) 2008-02-14 2022-05-02 Eli Lilly And Company Nowe środki obrazujące do wykrywania czynnościowych zaburzeń neurologicznych
JP5565647B2 (ja) * 2008-03-14 2014-08-06 よこはまティーエルオー株式会社 臓器領域特定方法、および臓器領域特定装置
KR20110046503A (ko) 2008-07-24 2011-05-04 지멘스 메디컬 솔루션즈 유에스에이, 인크. Ad 병인을 확인하기에 유용한 영상화제
JP5704533B2 (ja) * 2009-02-13 2015-04-22 国立大学法人大阪大学 アルツハイマー病の診断方法および診断薬
CN103739605B (zh) 2009-03-23 2016-08-17 伊莱利利公司 用于检测神经障碍的显像剂
US8691187B2 (en) 2009-03-23 2014-04-08 Eli Lilly And Company Imaging agents for detecting neurological disorders
JP5286395B2 (ja) * 2011-09-12 2013-09-11 富士フイルムRiファーマ株式会社 受容体結合能画像化プログラム、記録媒体及び方法
CN102936228B (zh) * 2012-11-08 2015-03-11 江苏省原子医学研究所 6-(2-氟乙氧基)-2-甲基苯并噁唑的制备方法

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