JP2002543079A - うつ病治療用のアザインドール誘導体 - Google Patents
うつ病治療用のアザインドール誘導体Info
- Publication number
- JP2002543079A JP2002543079A JP2000614250A JP2000614250A JP2002543079A JP 2002543079 A JP2002543079 A JP 2002543079A JP 2000614250 A JP2000614250 A JP 2000614250A JP 2000614250 A JP2000614250 A JP 2000614250A JP 2002543079 A JP2002543079 A JP 2002543079A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- pharmaceutically acceptable
- acceptable salt
- ring
- atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29673699A | 1999-04-22 | 1999-04-22 | |
US09/296,736 | 1999-04-22 | ||
PCT/US2000/010628 WO2000064898A1 (en) | 1999-04-22 | 2000-04-20 | Azaindole derivatives for the treatment of depression |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2002543079A true JP2002543079A (ja) | 2002-12-17 |
Family
ID=23143341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000614250A Pending JP2002543079A (ja) | 1999-04-22 | 2000-04-20 | うつ病治療用のアザインドール誘導体 |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1171439A1 (es) |
JP (1) | JP2002543079A (es) |
CN (1) | CN1348451A (es) |
AR (1) | AR028475A1 (es) |
AU (1) | AU4364400A (es) |
BR (1) | BR0010693A (es) |
CA (1) | CA2367681A1 (es) |
WO (1) | WO2000064898A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2479205A1 (en) * | 2002-03-28 | 2003-10-09 | Eisai Co., Ltd. | Azaindoles as inhibitors of c-jun n-terminal kinases |
US7635696B2 (en) | 2004-11-26 | 2009-12-22 | Janssen Pharmaceutica N.V. | Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic activity |
WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
US20100190777A1 (en) | 2007-07-17 | 2010-07-29 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
WO2010114928A2 (en) | 2009-04-03 | 2010-10-07 | F.Hoffmann-La Roche Ag | Compositions and uses thereof |
JP5721706B2 (ja) | 2009-06-17 | 2015-05-20 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルス複製の阻害剤 |
ES2633317T3 (es) | 2009-11-06 | 2017-09-20 | Plexxikon, Inc. | Compuestos y métodos para la modulación de quinasas, e indicaciones para ello |
CN103492381A (zh) | 2010-12-16 | 2014-01-01 | 沃泰克斯药物股份有限公司 | 流感病毒复制的抑制剂 |
AU2012214762B2 (en) | 2011-02-07 | 2015-08-13 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
AR085279A1 (es) | 2011-02-21 | 2013-09-18 | Plexxikon Inc | Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico |
UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
SI3421468T1 (sl) | 2013-11-13 | 2021-03-31 | Vertex Pharmaceuticals Incorporated | Postopki za pripravo inhibitorjev replikacije virusov influence |
CN105849100B (zh) | 2013-11-13 | 2019-07-16 | 沃泰克斯药物股份有限公司 | 流感病毒复制抑制剂 |
EP3294717B1 (en) | 2015-05-13 | 2020-07-29 | Vertex Pharmaceuticals Inc. | Methods of preparing inhibitors of influenza viruses replication |
JP6857617B2 (ja) | 2015-05-13 | 2021-04-14 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルスの複製の阻害剤 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5521197A (en) * | 1994-12-01 | 1996-05-28 | Eli Lilly And Company | 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists |
US5627196A (en) * | 1995-01-17 | 1997-05-06 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
US5576321A (en) * | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
-
2000
- 2000-04-19 AR ARP000101879A patent/AR028475A1/es unknown
- 2000-04-20 CA CA002367681A patent/CA2367681A1/en not_active Abandoned
- 2000-04-20 AU AU43644/00A patent/AU4364400A/en not_active Abandoned
- 2000-04-20 BR BR0010693-3A patent/BR0010693A/pt not_active Application Discontinuation
- 2000-04-20 EP EP00923540A patent/EP1171439A1/en not_active Withdrawn
- 2000-04-20 CN CN00806589A patent/CN1348451A/zh active Pending
- 2000-04-20 WO PCT/US2000/010628 patent/WO2000064898A1/en not_active Application Discontinuation
- 2000-04-20 JP JP2000614250A patent/JP2002543079A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AR028475A1 (es) | 2003-05-14 |
BR0010693A (pt) | 2002-02-05 |
WO2000064898A1 (en) | 2000-11-02 |
CA2367681A1 (en) | 2000-11-02 |
AU4364400A (en) | 2000-11-10 |
CN1348451A (zh) | 2002-05-08 |
EP1171439A1 (en) | 2002-01-16 |
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