IT8548210A0 - SOLID DISPERSION OF A PHARMACEUTICALLY ACTIVE AGENT, PARTICULARLY DIHYDROPYRIDINE, IN A WATER SOLUBLE CRYSTALLINE MATRIX, PHARMACEUTICAL COMPOSITION THAT CONTAINS IT AND PROCESS FOR THEIR PREPARATION - Google Patents

SOLID DISPERSION OF A PHARMACEUTICALLY ACTIVE AGENT, PARTICULARLY DIHYDROPYRIDINE, IN A WATER SOLUBLE CRYSTALLINE MATRIX, PHARMACEUTICAL COMPOSITION THAT CONTAINS IT AND PROCESS FOR THEIR PREPARATION

Info

Publication number
IT8548210A0
IT8548210A0 IT8548210A IT4821085A IT8548210A0 IT 8548210 A0 IT8548210 A0 IT 8548210A0 IT 8548210 A IT8548210 A IT 8548210A IT 4821085 A IT4821085 A IT 4821085A IT 8548210 A0 IT8548210 A0 IT 8548210A0
Authority
IT
Italy
Prior art keywords
preparation
pharmaceutical composition
active agent
water soluble
pharmaceutically active
Prior art date
Application number
IT8548210A
Other languages
Italian (it)
Other versions
IT1200080B (en
Inventor
Czarnecki Wolfgang
Gfeller Jean Claude
Bier Hans Peter
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8548210A0 publication Critical patent/IT8548210A0/en
Application granted granted Critical
Publication of IT1200080B publication Critical patent/IT1200080B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
IT8548210A 1984-06-14 1985-06-13 SOLID DISPERSION OF A PHARMACEUTICALLY ACTIVE AGENT, PARTICULARLY DIHYDROPYRIDINE, IN A WATER SOLUBLE CRYSTALLINE MATRIX, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PROCESS FOR THEIR PREPARATION IT1200080B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3422083 1984-06-14
DE3442566 1984-11-22

Publications (2)

Publication Number Publication Date
IT8548210A0 true IT8548210A0 (en) 1985-06-13
IT1200080B IT1200080B (en) 1989-01-05

Family

ID=25822108

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8548210A IT1200080B (en) 1984-06-14 1985-06-13 SOLID DISPERSION OF A PHARMACEUTICALLY ACTIVE AGENT, PARTICULARLY DIHYDROPYRIDINE, IN A WATER SOLUBLE CRYSTALLINE MATRIX, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PROCESS FOR THEIR PREPARATION

Country Status (21)

Country Link
AT (1) AT391806B (en)
AU (2) AU587190B2 (en)
BE (1) BE902626A (en)
CA (1) CA1264441A (en)
CY (1) CY1635A (en)
DE (1) DE3520184C2 (en)
DK (1) DK167649B1 (en)
ES (1) ES8702141A1 (en)
FR (1) FR2565822B1 (en)
GB (3) GB2160100B (en)
GR (1) GR851430B (en)
HK (1) HK25192A (en)
HU (1) HU198844B (en)
IE (1) IE58834B1 (en)
IL (1) IL75490A0 (en)
IT (1) IT1200080B (en)
LU (1) LU85946A1 (en)
NL (1) NL194389C (en)
NZ (1) NZ212390A (en)
PT (1) PT80635B (en)
SE (1) SE504583C2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1187751B (en) * 1985-10-15 1987-12-23 Eurand Spa PROCEDURE FOR THE PREPARATION OF SOLID FORMULATIONS OF NIFEDIPINE WITH HIGH BIO AVAILABILITY AND WITH PROLONGED EFFECT AND FORMULATIONS SO OBTAINED
US4816263A (en) * 1987-10-02 1989-03-28 Alza Corporation Dosage form for treating cardiovascular diseases comprising isradipine
WO1989009066A1 (en) * 1988-03-24 1989-10-05 Bukh Meditec A/S Controlled release composition
GR1000270B (en) * 1988-09-30 1992-05-12 Alza Corp Dose for cardiovascular troubles therapy
DK469989D0 (en) * 1989-09-22 1989-09-22 Bukh Meditec PHARMACEUTICAL PREPARATION
MX9300110A (en) * 1992-01-13 1994-07-29 Gerhard Gergely PHARMACEUTICAL PREPARATION IN THE FORM OF AN EFFERVESCENCE OR DISINTEGRATION TABLET OR OF AN INSTANT-TYPE GRANULATE AND PROCEDURE FOR ITS PREPARATION.
DE4201179A1 (en) * 1992-01-17 1993-07-22 Alfatec Pharma Gmbh Granulates or pellets comprising dispersion of active agent in hydrophilic macromolecules - are e.g. for treatment of depression, hypertension, rheumatism, etc.
US6726930B1 (en) 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
KR100321489B1 (en) 1996-07-08 2002-10-09 에드워드 멘델 컴파니 인코포레이티드 Sustained release matrix for high-dose insoluble drugs
DE19710009A1 (en) * 1997-03-12 1998-09-24 Knoll Ag Multi-phase preparation forms containing active ingredients
US6056977A (en) * 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US6787157B1 (en) 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
US7001892B1 (en) 1999-06-11 2006-02-21 Purdue Research Foundation Pharmaceutical materials and methods for their preparation and use
EP1189599A2 (en) * 1999-06-11 2002-03-27 Eli Lilly And Company Pharmaceutical materials and methods for their preparation and use
JP3462490B2 (en) * 1999-08-04 2003-11-05 山之内製薬株式会社 Stable oral pharmaceutical composition
IL143375A0 (en) 1999-09-30 2002-04-21 Penwest Pharmaceuticals Co Sustained release matrix systems for highly soluble drugs
EP1368006B1 (en) * 2001-02-13 2006-05-03 AstraZeneca AB Novel modified released formulation
US7135436B2 (en) 2003-05-05 2006-11-14 J.F. Daley International, Ltd. Solid algicide, preparation and usage in recirculating water
EP1690528A1 (en) 2005-02-11 2006-08-16 Abbott GmbH & Co. KG Process for the preparation of dosage forms comprising a solid dispersion of a microcrystalline active agent
US8399007B2 (en) 2006-12-05 2013-03-19 Landec Corporation Method for formulating a controlled-release pharmaceutical formulation
WO2008070118A1 (en) 2006-12-05 2008-06-12 Landec Corporation Drug delivery
US8114883B2 (en) 2007-12-04 2012-02-14 Landec Corporation Polymer formulations for delivery of bioactive materials
RU2483713C2 (en) 2008-08-20 2013-06-10 Борд Оф Риджентс, Зе Юниверсити Оф Техас Систем Extrusion of hot liquid of multiple particles with modified release

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617362A1 (en) * 1967-11-17 1971-03-25 Beiersdorf Ag Process for the production of medicaments with delayed release of active substances in the form of capsules
DE2400819C2 (en) * 1974-01-09 1982-04-22 Bayer Ag, 5090 Leverkusen Process for the production of solid preparations of poorly soluble active pharmaceutical ingredients in extremely fine distribution
DE2546577B2 (en) * 1975-10-17 1981-04-02 Sandoz-Patent-GmbH, 7850 Lörrach Solid substances made from polyvinylpyrrolidone and ergot alkaloids
DE2549740A1 (en) * 1975-11-17 1977-05-18 Sandoz Ag NEW GALENIC FORMS AND METHODS FOR THEIR PRODUCTION
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
FI64938C (en) * 1977-06-20 1984-02-10 Sandoz Ag PROCEDURE FOR THE FRAMEWORK OF THERAPEUTIC THERAPEUTIC BENSOX A- AND OX BENZOTIADIAZOLYL-1,4-DIHYDROPYRID DERIVATIVES
CH639659A5 (en) * 1978-12-18 1983-11-30 Sandoz Ag NEW 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE.
EP0001247A1 (en) * 1977-09-14 1979-04-04 Kanebo, Ltd. Pharmaceutical preparation containing nifedipine and a method for producing the same.
DK154607C (en) * 1978-12-21 1989-06-05 Sandoz Ag PROCEDURE FOR PREPARING A PHARMACEUTICAL FORM FOR ORAL ADMINISTRATION OF ERGOTAL KALOIDS
DE2904310A1 (en) * 1979-02-05 1980-08-07 Boehringer Mannheim Gmbh MOLDINGS WITH RETARDED ACTIVE SUBSTANCE RELEASE AND METHOD FOR THE PRODUCTION THEREOF
JPS56115726A (en) * 1980-02-20 1981-09-11 Kaken Pharmaceut Co Ltd Pharmaceutical containing nifedipine
DE3033919A1 (en) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen SOLID PHARMACEUTICAL PREPARATIONS CONTAINING NIFEDIPINE AND METHOD FOR THE PRODUCTION THEREOF
US4442112A (en) * 1981-09-02 1984-04-10 Sandoz Ltd. Dihydropyridine derivatives useful in treating vascular headaches
DE3270785D1 (en) * 1981-10-29 1986-05-28 Bayer Ag Process for preparing solid fast-releasing drug formulations of dihydropyridines
CA1208558A (en) * 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
DE3318649A1 (en) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen TWO-PHASE FORMULATION

Also Published As

Publication number Publication date
GB2196852A (en) 1988-05-11
HK25192A (en) 1992-04-10
FR2565822A1 (en) 1985-12-20
DK167649B1 (en) 1993-12-06
IE851460L (en) 1985-12-14
PT80635A (en) 1985-07-01
DK264785D0 (en) 1985-06-12
GB8727056D0 (en) 1987-12-23
SE8502950D0 (en) 1985-06-13
AT391806B (en) 1990-12-10
GB8514855D0 (en) 1985-07-17
AU587190B2 (en) 1989-08-10
NL194389C (en) 2002-03-04
CA1264441A (en) 1990-01-16
DE3520184A1 (en) 1985-12-19
CY1635A (en) 1992-11-06
BE902626A (en) 1985-12-10
LU85946A1 (en) 1986-01-24
ATA174885A (en) 1990-06-15
GB2160100B (en) 1989-06-01
GR851430B (en) 1985-11-25
IT1200080B (en) 1989-01-05
SE8502950L (en) 1985-12-15
DK264785A (en) 1985-12-15
GB2196851A (en) 1988-05-11
GB2160100A (en) 1985-12-18
GB8727055D0 (en) 1987-12-23
HU198844B (en) 1989-12-28
AU4454389A (en) 1990-03-22
GB2196852B (en) 1989-05-17
SE504583C2 (en) 1997-03-10
NZ212390A (en) 1992-02-25
NL194389B (en) 2001-11-01
NL8501578A (en) 1986-01-02
HUT40918A (en) 1987-03-30
IE58834B1 (en) 1993-11-17
DE3520184C2 (en) 1997-03-13
ES544075A0 (en) 1987-01-01
IL75490A0 (en) 1985-10-31
GB2196851B (en) 1989-06-07
ES8702141A1 (en) 1987-01-01
AU4348685A (en) 1985-12-19
PT80635B (en) 1987-10-20
FR2565822B1 (en) 1989-02-17

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970623