IT8419945A0 - Procedimento per la preparazione di carbapenem derivati. - Google Patents

Procedimento per la preparazione di carbapenem derivati.

Info

Publication number: IT8419945A0
Authority: IT; Italy
Prior art keywords: procedure; preparation; carbapenem derivatives; carbapenem; derivatives
Prior art date: 1983-03-08

Application number

IT8419945A

Other languages

English (en)

Other versions

IT1178465B (it

Inventor

Pierre Dextraze

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-08

Filing date

1984-03-07

Publication date

1984-03-07

1984-03-07 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1984-03-07 Publication of IT8419945A0 publication Critical patent/IT8419945A0/it

1987-09-09 Application granted granted Critical

1987-09-09 Publication of IT1178465B publication Critical patent/IT1178465B/it

Links

YZBQHRLRFGPBSL-RXMQYKEDSA-N carbapenem Chemical class C1C=CN2C(=O)C[C@H]21 YZBQHRLRFGPBSL-RXMQYKEDSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)

IT19945/84A 1983-03-08 1984-03-07 Procedimento per la preparazione di carbapenem derivati IT1178465B (it)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US47137883A	1983-03-08	1983-03-08
US49969183A	1983-06-07	1983-06-07
US55729583A	1983-12-01	1983-12-01

Publications (2)

Publication Number	Publication Date
IT8419945A0 true IT8419945A0 (it)	1984-03-07
IT1178465B IT1178465B (it)	1987-09-09

Family

ID=27413179

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT19945/84A IT1178465B (it)	1983-03-08	1984-03-07	Procedimento per la preparazione di carbapenem derivati

Country Status (31)

Country	Link
JP (1)	JPH05255250A (it)
KR (1)	KR900002247B1 (it)
AR (1)	AR241016A1 (it)
AT (1)	AT387968B (it)
AU (2)	AU572124B2 (it)
CA (1)	CA1284324C (it)
CH (1)	CH658248A5 (it)
CY (1)	CY1546A (it)
DD (1)	DD228258A5 (it)
DE (1)	DE3408347A1 (it)
DK (1)	DK140584A (it)
ES (2)	ES8505205A1 (it)
FI (1)	FI840863A (it)
FR (1)	FR2542316B1 (it)
GB (1)	GB2136802B (it)
GR (1)	GR81871B (it)
HK (1)	HK82990A (it)
HU (1)	HU193895B (it)
IE (1)	IE57098B1 (it)
IL (1)	IL71149A (it)
IT (1)	IT1178465B (it)
LU (1)	LU85241A1 (it)
NL (1)	NL8400702A (it)
NO (1)	NO166038C (it)
NZ (1)	NZ207346A (it)
OA (1)	OA07674A (it)
PT (1)	PT78211B (it)
SE (2)	SE8401278L (it)
SG (1)	SG35490G (it)
YU (2)	YU46147B (it)
ZW (1)	ZW3884A1 (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4683301A (en) *	1982-04-08	1987-07-28	Bristol-Myers Company	Carbapenem antibiotics
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
CA1285940C (en) *	1984-07-02	1991-07-09	Merck & Co., Inc.	Carbapenems having a 2-quaternary heteroarylalkylthio substituent
IE851586L (en) *	1984-07-02	1986-01-02	Interchem Internat S A	I methylcarbapenems having a 2-quaternary¹heteroarylalkylthio substituent
US4665169A (en) *	1985-09-11	1987-05-12	Bristol-Myers Company	Carbapenem antibiotics
US4880922A (en) *	1985-11-22	1989-11-14	Bristol-Myers Company	Carbapenems with quaternized heterothioalkylthio substitution at position 2
NZ219892A (en) *	1986-04-15	1991-02-26	Merck & Co Inc	N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof
IE910606A1 (en) *	1990-02-23	1991-08-28	Sankyo Co	Carbapenem derivatives having antibiotic activity, their¹preparation and their use
US5712267A (en) *	1991-06-04	1998-01-27	Sankyo Company,. Limited	Carbapenem derivatives, their preparation and their use as antibiotics
ATE348818T1 (de)	2003-06-12	2007-01-15	Btg Int Ltd	Cyclische hydroxylamine als psychoactive verbindugen
FR2921258A1 (fr) *	2007-09-24	2009-03-27	Oreal	Composition tinctoriale comprenant au moins un precurseur incolore disulfures/thiol, proced de coloration a partir de la composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55147284A (en) *	1979-04-17	1980-11-17	Sanraku Inc	Novel beta-lactam derivative and its preparation
IE52147B1 (en) *	1980-03-27	1987-07-08	Merck & Co Inc	4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0038869A1 (en) *	1980-04-30	1981-11-04	Merck & Co. Inc.	Process for the preparation of 1-carbapenems, and intermediates for their preparation
EP0060612A1 (en) *	1981-02-04	1982-09-22	Beecham Group Plc	Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
US4552873A (en) *	1981-08-19	1985-11-12	Sankyo Company Limited	Carbapenem compounds, and compositions containing them
EP0074599A1 (en) *	1981-09-09	1983-03-23	Takeda Chemical Industries, Ltd.	5,6-cis-Carbapenem derivatives, their production and use
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
US4536335A (en) *	1982-06-18	1985-08-20	Bristol-Myers Company	Carbapenem antibiotics

1984
- 1984-02-29 DK DK140584A patent/DK140584A/da not_active Application Discontinuation
- 1984-02-29 AR AR295877A patent/AR241016A1/es active
- 1984-03-01 NZ NZ207346A patent/NZ207346A/en unknown
- 1984-03-05 ZW ZW38/84A patent/ZW3884A1/xx unknown
- 1984-03-05 FI FI840863A patent/FI840863A/fi not_active Application Discontinuation
- 1984-03-05 NL NL8400702A patent/NL8400702A/xx not_active Application Discontinuation
- 1984-03-05 IL IL71149A patent/IL71149A/xx unknown
- 1984-03-06 CH CH1103/84A patent/CH658248A5/de not_active IP Right Cessation
- 1984-03-06 GR GR73999A patent/GR81871B/el unknown
- 1984-03-06 CA CA000448904A patent/CA1284324C/en not_active Expired - Fee Related
- 1984-03-07 DD DD84260663A patent/DD228258A5/de not_active IP Right Cessation
- 1984-03-07 GB GB08405984A patent/GB2136802B/en not_active Expired
- 1984-03-07 AT AT0076984A patent/AT387968B/de not_active IP Right Cessation
- 1984-03-07 IT IT19945/84A patent/IT1178465B/it active
- 1984-03-07 HU HU84911A patent/HU193895B/hu not_active IP Right Cessation
- 1984-03-07 OA OA58247A patent/OA07674A/xx unknown
- 1984-03-07 PT PT78211A patent/PT78211B/pt unknown
- 1984-03-07 FR FR8403553A patent/FR2542316B1/fr not_active Expired
- 1984-03-07 ES ES530337A patent/ES8505205A1/es not_active Expired
- 1984-03-07 LU LU85241A patent/LU85241A1/fr unknown
- 1984-03-07 NO NO840865A patent/NO166038C/no unknown
- 1984-03-07 AU AU25360/84A patent/AU572124B2/en not_active Ceased
- 1984-03-07 DE DE19843408347 patent/DE3408347A1/de not_active Withdrawn
- 1984-03-07 SE SE8401278A patent/SE8401278L/xx not_active Application Discontinuation
- 1984-03-07 IE IE549/84A patent/IE57098B1/en not_active IP Right Cessation
- 1984-03-08 YU YU42084A patent/YU46147B/sh unknown
- 1984-03-08 KR KR1019840001243A patent/KR900002247B1/ko not_active IP Right Cessation
- 1984-11-02 ES ES537349A patent/ES8507145A1/es not_active Expired
1986
- 1986-03-28 YU YU49486A patent/YU46305B/sh unknown
1987
- 1987-07-20 AU AU75924/87A patent/AU605491B2/en not_active Ceased
1989
- 1989-04-03 SE SE8901162A patent/SE8901162L/xx not_active Application Discontinuation
1990
- 1990-05-19 SG SG35490A patent/SG35490G/en unknown
- 1990-10-11 HK HK829/90A patent/HK82990A/xx unknown
1991
- 1991-03-22 CY CY1546A patent/CY1546A/xx unknown
- 1991-09-27 JP JP3274949A patent/JPH05255250A/ja active Pending

Also Published As

Publication number	Publication date
ATA76984A (de)	1988-09-15
AU605491B2 (en)	1991-01-17
ES530337A0 (es)	1985-05-16
DD228258A5 (de)	1985-10-09
FR2542316B1 (fr)	1988-10-07
ZW3884A1 (en)	1984-10-10
SE8901162D0 (sv)	1989-04-03
FI840863A (fi)	1984-09-09
IT1178465B (it)	1987-09-09
HUT34980A (en)	1985-05-28
IE57098B1 (en)	1992-04-22
YU46147B (sh)	1993-05-28
ES537349A0 (es)	1985-08-16
DK140584A (da)	1984-09-09
CH658248A5 (de)	1986-10-31
NO840865L (no)	1984-09-10
NO166038B (no)	1991-02-11
SG35490G (en)	1990-07-13
GB2136802A (en)	1984-09-26
LU85241A1 (fr)	1984-11-14
CA1284324C (en)	1991-05-21
FR2542316A1 (fr)	1984-09-14
SE8401278D0 (sv)	1984-03-07
PT78211A (en)	1984-04-01
ES8505205A1 (es)	1985-05-16
SE8901162L (sv)	1989-04-03
ES8507145A1 (es)	1985-08-16
FI840863A0 (fi)	1984-03-05
NZ207346A (en)	1987-01-23
GB2136802B (en)	1987-05-20
AR241016A1 (es)	1991-04-30
AU7592487A (en)	1987-10-22
YU42084A (en)	1986-08-31
AU2536084A (en)	1984-09-13
GR81871B (it)	1984-12-12
PT78211B (en)	1986-08-12
AU572124B2 (en)	1988-05-05
AT387968B (de)	1989-04-10
HK82990A (en)	1990-10-19
IL71149A0 (en)	1984-06-29
AR241016A2 (es)	1991-04-30
JPH05255250A (ja)	1993-10-05
DE3408347A1 (de)	1984-09-13
KR900002247B1 (ko)	1990-04-07
NO166038C (no)	1991-05-22
HU193895B (en)	1987-12-28
DK140584D0 (da)	1984-02-29
IL71149A (en)	1990-03-19
IE840549L (en)	1984-09-08
GB8405984D0 (en)	1984-04-11
NL8400702A (nl)	1984-10-01
YU46305B (sh)	1993-05-28
SE8401278L (sv)	1984-09-09
OA07674A (fr)	1985-05-23
YU49486A (en)	1987-12-31
KR840008157A (ko)	1984-12-13
CY1546A (en)	1991-03-22

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NO842273L (no)	1984-12-10	Fremgangsmaate ved fremstilling av aminomethyloxooxazolidinylbenzenderivater.
IT8422234A0 (it)	1984-08-06	Procedimento per la preparazione di penem.
IT8125755A0 (it)	1981-12-22	Metodo per la preparazione di gem-diammino derivati n-monoacilati.
ES537393A0 (es)	1985-11-16	Procedimiento para la preparacion de derivados succilinados de la heparina n-desulfatada.
ES538464A0 (es)	1985-11-01	Procedimiento para la preparacion de derivados de acilamida.
IT8224053A0 (it)	1982-11-03	Procedimento per la preparazione di derivati di eburnamonina.
IT8419945A0 (it)	1984-03-07	Procedimento per la preparazione di carbapenem derivati.
ES541705A0 (es)	1985-12-01	Procedimiento para la preparacion de derivados de tiazolidina.
ES546506A0 (es)	1986-02-16	Procedimiento para la preparacion de nuevos derivados de 3-fenil-4-cianopirrol.
AR240460A1 (es)	1990-04-30	Procedimeitno para la preparacion de derivados de antraciclina.
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