HUT34980A - Process for producing carbapeneme derivatives - Google Patents

Process for producing carbapeneme derivatives

Info

Publication number: HUT34980A
Authority: HU; Hungary
Prior art keywords: producing; carbapeneme derivatives; carbapeneme; derivatives; producing carbapeneme
Prior art date: 1983-03-08

Application number

HU84911A

Other languages

Hungarian (hu)

Other versions

HU193895B (en

Inventor

Pierre Dextraze

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-08

Filing date

1984-03-07

Publication date

1985-05-28

1984-03-07 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1985-05-28 Publication of HUT34980A publication Critical patent/HUT34980A/en

1987-12-28 Publication of HU193895B publication Critical patent/HU193895B/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)

HU84911A 1983-03-08 1984-03-07 Process for preparing carbapenem derivatives HU193895B (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US47137883A	1983-03-08	1983-03-08
US49969183A	1983-06-07	1983-06-07
US55729583A	1983-12-01	1983-12-01

Publications (2)

Publication Number	Publication Date
HUT34980A true HUT34980A (en)	1985-05-28
HU193895B HU193895B (en)	1987-12-28

Family

ID=27413179

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU84911A HU193895B (en)	1983-03-08	1984-03-07	Process for preparing carbapenem derivatives

Country Status (31)

Country	Link
JP (1)	JPH05255250A (en)
KR (1)	KR900002247B1 (en)
AR (1)	AR241016A1 (en)
AT (1)	AT387968B (en)
AU (2)	AU572124B2 (en)
CA (1)	CA1284324C (en)
CH (1)	CH658248A5 (en)
CY (1)	CY1546A (en)
DD (1)	DD228258A5 (en)
DE (1)	DE3408347A1 (en)
DK (1)	DK140584A (en)
ES (2)	ES530337A0 (en)
FI (1)	FI840863A (en)
FR (1)	FR2542316B1 (en)
GB (1)	GB2136802B (en)
GR (1)	GR81871B (en)
HK (1)	HK82990A (en)
HU (1)	HU193895B (en)
IE (1)	IE57098B1 (en)
IL (1)	IL71149A (en)
IT (1)	IT1178465B (en)
LU (1)	LU85241A1 (en)
NL (1)	NL8400702A (en)
NO (1)	NO166038C (en)
NZ (1)	NZ207346A (en)
OA (1)	OA07674A (en)
PT (1)	PT78211B (en)
SE (2)	SE8401278L (en)
SG (1)	SG35490G (en)
YU (2)	YU46147B (en)
ZW (1)	ZW3884A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4683301A (en) *	1982-04-08	1987-07-28	Bristol-Myers Company	Carbapenem antibiotics
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
IE851586L (en) *	1984-07-02	1986-01-02	Interchem Internat S A	I methylcarbapenems having a 2-quaternary¹heteroarylalkylthio substituent
CA1285940C (en) *	1984-07-02	1991-07-09	Merck & Co., Inc.	Carbapenems having a 2-quaternary heteroarylalkylthio substituent
US4665169A (en) *	1985-09-11	1987-05-12	Bristol-Myers Company	Carbapenem antibiotics
US4880922A (en) *	1985-11-22	1989-11-14	Bristol-Myers Company	Carbapenems with quaternized heterothioalkylthio substitution at position 2
NZ219892A (en) *	1986-04-15	1991-02-26	Merck & Co Inc	N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof
CA2036941A1 (en) *	1990-02-23	1991-08-24	Isao Kawamoto	Carbapenem derivatives having antibiotic activity, their preparation and their use
US5712267A (en) *	1991-06-04	1998-01-27	Sankyo Company,. Limited	Carbapenem derivatives, their preparation and their use as antibiotics
ES2278321T3 (en)	2003-06-12	2007-08-01	Btg International Limited	CYCLIC HYDROXYLAMINE AS PSYCHOACTIVE COMPOUNDS.
FR2921258A1 (en) *	2007-09-24	2009-03-27	Oreal	TINCTORIAL COMPOSITION COMPRISING AT LEAST ONE COLOR DISULFIDE / THIOL PRECURSOR, COLORING PROCESS FROM THE COMPOSITION

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55147284A (en) *	1979-04-17	1980-11-17	Sanraku Inc	Novel beta-lactam derivative and its preparation
IE52147B1 (en) *	1980-03-27	1987-07-08	Merck & Co Inc	4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0038869A1 (en) *	1980-04-30	1981-11-04	Merck & Co. Inc.	Process for the preparation of 1-carbapenems, and intermediates for their preparation
EP0060612A1 (en) *	1981-02-04	1982-09-22	Beecham Group Plc	Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
US4552873A (en) *	1981-08-19	1985-11-12	Sankyo Company Limited	Carbapenem compounds, and compositions containing them
EP0074599A1 (en) *	1981-09-09	1983-03-23	Takeda Chemical Industries, Ltd.	5,6-cis-Carbapenem derivatives, their production and use
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
US4536335A (en) *	1982-06-18	1985-08-20	Bristol-Myers Company	Carbapenem antibiotics

1984
- 1984-02-29 AR AR295877A patent/AR241016A1/en active
- 1984-02-29 DK DK140584A patent/DK140584A/en not_active Application Discontinuation
- 1984-03-01 NZ NZ207346A patent/NZ207346A/en unknown
- 1984-03-05 FI FI840863A patent/FI840863A/en not_active Application Discontinuation
- 1984-03-05 ZW ZW38/84A patent/ZW3884A1/en unknown
- 1984-03-05 NL NL8400702A patent/NL8400702A/en not_active Application Discontinuation
- 1984-03-05 IL IL71149A patent/IL71149A/en unknown
- 1984-03-06 CA CA000448904A patent/CA1284324C/en not_active Expired - Fee Related
- 1984-03-06 GR GR73999A patent/GR81871B/el unknown
- 1984-03-06 CH CH1103/84A patent/CH658248A5/en not_active IP Right Cessation
- 1984-03-07 DE DE19843408347 patent/DE3408347A1/en not_active Withdrawn
- 1984-03-07 IE IE549/84A patent/IE57098B1/en not_active IP Right Cessation
- 1984-03-07 DD DD84260663A patent/DD228258A5/en not_active IP Right Cessation
- 1984-03-07 FR FR8403553A patent/FR2542316B1/en not_active Expired
- 1984-03-07 AT AT0076984A patent/AT387968B/en not_active IP Right Cessation
- 1984-03-07 IT IT19945/84A patent/IT1178465B/en active
- 1984-03-07 ES ES530337A patent/ES530337A0/en active Granted
- 1984-03-07 GB GB08405984A patent/GB2136802B/en not_active Expired
- 1984-03-07 SE SE8401278A patent/SE8401278L/en not_active Application Discontinuation
- 1984-03-07 OA OA58247A patent/OA07674A/en unknown
- 1984-03-07 AU AU25360/84A patent/AU572124B2/en not_active Ceased
- 1984-03-07 HU HU84911A patent/HU193895B/en not_active IP Right Cessation
- 1984-03-07 NO NO840865A patent/NO166038C/en unknown
- 1984-03-07 LU LU85241A patent/LU85241A1/en unknown
- 1984-03-07 PT PT78211A patent/PT78211B/en unknown
- 1984-03-08 YU YU42084A patent/YU46147B/en unknown
- 1984-03-08 KR KR1019840001243A patent/KR900002247B1/en not_active IP Right Cessation
- 1984-11-02 ES ES537349A patent/ES537349A0/en active Granted
1986
- 1986-03-28 YU YU49486A patent/YU46305B/en unknown
1987
- 1987-07-20 AU AU75924/87A patent/AU605491B2/en not_active Ceased
1989
- 1989-04-03 SE SE8901162A patent/SE8901162D0/en not_active Application Discontinuation
1990
- 1990-05-19 SG SG35490A patent/SG35490G/en unknown
- 1990-10-11 HK HK829/90A patent/HK82990A/en unknown
1991
- 1991-03-22 CY CY1546A patent/CY1546A/en unknown
- 1991-09-27 JP JP3274949A patent/JPH05255250A/en active Pending

Also Published As

Publication number	Publication date
KR840008157A (en)	1984-12-13
HU193895B (en)	1987-12-28
AU7592487A (en)	1987-10-22
SE8901162L (en)	1989-04-03
NO166038C (en)	1991-05-22
CY1546A (en)	1991-03-22
IL71149A0 (en)	1984-06-29
SE8901162D0 (en)	1989-04-03
DK140584D0 (en)	1984-02-29
IL71149A (en)	1990-03-19
GB2136802B (en)	1987-05-20
LU85241A1 (en)	1984-11-14
ATA76984A (en)	1988-09-15
AU605491B2 (en)	1991-01-17
JPH05255250A (en)	1993-10-05
YU49486A (en)	1987-12-31
KR900002247B1 (en)	1990-04-07
SE8401278D0 (en)	1984-03-07
PT78211A (en)	1984-04-01
FI840863A0 (en)	1984-03-05
NO840865L (en)	1984-09-10
GB2136802A (en)	1984-09-26
ZW3884A1 (en)	1984-10-10
GR81871B (en)	1984-12-12
IT1178465B (en)	1987-09-09
NZ207346A (en)	1987-01-23
YU46147B (en)	1993-05-28
IE57098B1 (en)	1992-04-22
YU42084A (en)	1986-08-31
CH658248A5 (en)	1986-10-31
SG35490G (en)	1990-07-13
AR241016A2 (en)	1991-04-30
ES8505205A1 (en)	1985-05-16
SE8401278L (en)	1984-09-09
FR2542316A1 (en)	1984-09-14
AU572124B2 (en)	1988-05-05
ES8507145A1 (en)	1985-08-16
NL8400702A (en)	1984-10-01
HK82990A (en)	1990-10-19
OA07674A (en)	1985-05-23
ES530337A0 (en)	1985-05-16
YU46305B (en)	1993-05-28
IT8419945A0 (en)	1984-03-07
GB8405984D0 (en)	1984-04-11
AR241016A1 (en)	1991-04-30
AU2536084A (en)	1984-09-13
DD228258A5 (en)	1985-10-09
PT78211B (en)	1986-08-12
FI840863A (en)	1984-09-09
IE840549L (en)	1984-09-08
ES537349A0 (en)	1985-08-16
DK140584A (en)	1984-09-09
NO166038B (en)	1991-02-11
FR2542316B1 (en)	1988-10-07
AT387968B (en)	1989-04-10
DE3408347A1 (en)	1984-09-13
CA1284324C (en)	1991-05-21

Legal Events

Date	Code	Title	Description
1990-06-28	HU90	Patent valid on 900628
1994-12-28	HMM4	Cancellation of final prot. due to non-payment of fee

Publication	Publication Date	Title
DE3473604D1 (en)	1988-09-29	Process for producing polyetherglycol
YU202784A (en)	1987-02-28	Process for making sfingozine derivatives
HUT35696A (en)	1985-07-29	Process for producing grf-analoques
HUT36841A (en)	1985-10-28	Process for producing 2-fluoro-17-beta-estradiol
HUT34004A (en)	1985-01-28	Process for preparing n-aryl-alpha-amino-carboxamide derivatives
HUT35697A (en)	1985-07-29	Process for preparing n-acyl-glucopeptide derivatives
YU43357B (en)	1989-06-30	Process for making ergolinic derivatives
HUT34980A (en)	1985-05-28	Process for producing carbapeneme derivatives
GB2151613B (en)	1987-03-18	Process for producing 4-alkoxyanilines
HUT36459A (en)	1985-09-30	Process for preparing difluoro-pyridine derivatives
HUT37434A (en)	1985-12-28	Process for producing acylamino-mitosanes
HUT35679A (en)	1985-07-29	Process for preparing pyrazolo-pyridine-cycloalkanone derivatives
HUT35264A (en)	1985-06-28	Process for producing 2-azacyclo-alkyil-thio-peneme derivatives
PL248114A1 (en)	1985-04-09	Process for preparing penemic derivatives
HUT35251A (en)	1985-06-28	Process for preparing fluorenyl-alkyl-imidazole derivatives
HUT34977A (en)	1985-05-28	Process for preparing naphthyl-imidazo-pyridine derivatives
HUT34197A (en)	1985-02-28	Process for producing spiro-chroman-imidazolidine derivatives
HUT34195A (en)	1985-02-28	Process for producing spiro-imidazolidin-indoline derivatives
HUT34496A (en)	1985-03-28	Process for producing indolyl-glycyl-cepheme derivatives
HUT37930A (en)	1986-03-28	Process for producing tricyclie thiadiazinon derivatives
HUT36091A (en)	1985-08-28	Process for producing new aryloxy-cyclosalkanol-amino-alkylene-arylketone derivatives
DE3460771D1 (en)	1986-10-23	Process for producing arginyl-p-nitroanilide
YU44984B (en)	1991-06-30	Process for making new derivatives
HUT35244A (en)	1985-06-28	Process for preparing phenyl-ethyl-amine derivatives
GB2140420B (en)	1986-11-19	Process for producing 2-quinoxalinols