IT8403463A0 - Processo per la preparazionedi pirido-imidazo-rifamicine - Google Patents

Processo per la preparazionedi pirido-imidazo-rifamicine

Info

Publication number
IT8403463A0
IT8403463A0 IT8403463A IT346384A IT8403463A0 IT 8403463 A0 IT8403463 A0 IT 8403463A0 IT 8403463 A IT8403463 A IT 8403463A IT 346384 A IT346384 A IT 346384A IT 8403463 A0 IT8403463 A0 IT 8403463A0
Authority
IT
Italy
Prior art keywords
rifamicins
pyrido
imidazo
preparation
Prior art date
Application number
IT8403463A
Other languages
English (en)
Other versions
IT1199374B (it
Inventor
Vincenzo Cannata
G Franco Tomagnonesilva Marchi
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Publication of IT8403463A0 publication Critical patent/IT8403463A0/it
Priority to IT03463/84A priority Critical patent/IT1199374B/it
Priority to DE8585104790T priority patent/DE3573120D1/de
Priority to AT85104790T priority patent/ATE46512T1/de
Priority to ZA852971A priority patent/ZA852971B/xx
Priority to EP85104790A priority patent/EP0161534B1/en
Priority to PH32186A priority patent/PH22007A/en
Priority to US06/727,521 priority patent/US4557866A/en
Priority to CA000480321A priority patent/CA1215708A/en
Priority to GR851144A priority patent/GR851144B/el
Priority to PT80446A priority patent/PT80446B/pt
Priority to ES543115A priority patent/ES543115A0/es
Priority to JP60102528A priority patent/JPS60252483A/ja
Priority to IE119185A priority patent/IE58392B1/en
Priority to NO851921A priority patent/NO164242C/no
Priority to DK214685A priority patent/DK162647C/da
Priority to FI851907A priority patent/FI81101C/fi
Priority to AR85300385A priority patent/AR241913A1/es
Priority to AU42515/85A priority patent/AU568934B2/en
Application granted granted Critical
Publication of IT1199374B publication Critical patent/IT1199374B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT03463/84A 1984-05-15 1984-05-15 Processo per la preparazione di pirido-imidazo-rifamicine IT1199374B (it)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IT03463/84A IT1199374B (it) 1984-05-15 1984-05-15 Processo per la preparazione di pirido-imidazo-rifamicine
DE8585104790T DE3573120D1 (en) 1984-05-15 1985-04-19 New process for the synthesis of pyrido-imidazo-refamycins
AT85104790T ATE46512T1 (de) 1984-05-15 1985-04-19 Verfahren zur synthese von pyridoimidazorifamycin.
ZA852971A ZA852971B (en) 1984-05-15 1985-04-19 New process for the synthesis of pyrido-imidazo rifamycins
EP85104790A EP0161534B1 (en) 1984-05-15 1985-04-19 New process for the synthesis of pyrido-imidazo-refamycins
PH32186A PH22007A (en) 1984-05-15 1985-04-25 A new process for the synthesis of pyridoimidazorifaycins
US06/727,521 US4557866A (en) 1984-05-15 1985-04-26 Process for the synthesis of pyrido-imidazo rifamycins
CA000480321A CA1215708A (en) 1984-05-15 1985-04-29 New process for the synthesis of pyrido-imidazo- rifamycins
GR851144A GR851144B (it) 1984-05-15 1985-05-13
PT80446A PT80446B (pt) 1984-05-15 1985-05-13 Novo processo para a sintese de pirido-imidazo-rifamicinas
ES543115A ES543115A0 (es) 1984-05-15 1985-05-14 Un nuevo procedimiento para la preparacion de pirido-imidazorifamicinas
JP60102528A JPS60252483A (ja) 1984-05-15 1985-05-14 ピリド‐イミダゾリフアマイシンの新規製造法
IE119185A IE58392B1 (en) 1984-05-15 1985-05-14 A new process for the synthesis of pyrido-imidazo-rifamycins
NO851921A NO164242C (no) 1984-05-15 1985-05-14 Fremgangsmaate for fremstilling av pyrido-imidazo-rifamycin-derivater.
DK214685A DK162647C (da) 1984-05-15 1985-05-14 Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner
FI851907A FI81101C (fi) 1984-05-15 1985-05-14 Nytt foerfarande foer syntetisering av pyridoimidazorifamyciner.
AR85300385A AR241913A1 (es) 1984-05-15 1985-05-15 Un nuevo procedimiento para la preparacion de rifamicinas pirido-imidazo.
AU42515/85A AU568934B2 (en) 1984-05-15 1985-05-15 New process for the synthesis of pyrido-imidazo-rifamycins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03463/84A IT1199374B (it) 1984-05-15 1984-05-15 Processo per la preparazione di pirido-imidazo-rifamicine

Publications (2)

Publication Number Publication Date
IT8403463A0 true IT8403463A0 (it) 1984-05-15
IT1199374B IT1199374B (it) 1988-12-30

Family

ID=11107845

Family Applications (1)

Application Number Title Priority Date Filing Date
IT03463/84A IT1199374B (it) 1984-05-15 1984-05-15 Processo per la preparazione di pirido-imidazo-rifamicine

Country Status (18)

Country Link
US (1) US4557866A (it)
EP (1) EP0161534B1 (it)
JP (1) JPS60252483A (it)
AR (1) AR241913A1 (it)
AT (1) ATE46512T1 (it)
AU (1) AU568934B2 (it)
CA (1) CA1215708A (it)
DE (1) DE3573120D1 (it)
DK (1) DK162647C (it)
ES (1) ES543115A0 (it)
FI (1) FI81101C (it)
GR (1) GR851144B (it)
IE (1) IE58392B1 (it)
IT (1) IT1199374B (it)
NO (1) NO164242C (it)
PH (1) PH22007A (it)
PT (1) PT80446B (it)
ZA (1) ZA852971B (it)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
WO2003051299A2 (en) * 2001-12-13 2003-06-26 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
US7906542B2 (en) 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US7902206B2 (en) 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US7923553B2 (en) 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US8003118B2 (en) * 2005-03-02 2011-08-23 Kodsi Robert E Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis
US20060210483A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
US20060210492A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Use of rifaximin for treatment and prevention of periodontal conditions
PT1698630E (pt) * 2005-03-03 2014-09-15 Alfa Wassermann Spa Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais
ITBO20050123A1 (it) 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
PT1996710T (pt) 2006-03-09 2019-10-25 Salix Pharmaceuticals Inc Preparação da disfunção anti-rectal de rifaximina.
BRPI0714724A8 (pt) 2006-08-02 2018-04-10 Salix Pharmaceuticals Inc métodos para tratar enterite, para proteger contra a enterite, contra a lesão à mucosa do cólon e contra a inflamação colorretal induzidas pela radiação, para tratar enterite em um indivíduo ou monitorar o progresso de um indivíduo que é tratado de enterite, para selecionar um indivíduo para o tratamento de enterite, e, para tratar diarréia profilaticamente.
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
NZ575550A (en) * 2006-09-22 2011-12-22 Cipla Ltd Rifaximin
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
US7709634B2 (en) 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
EA021176B1 (ru) 2008-02-25 2015-04-30 Сэликс Фармасьютиклз, Лтд. Полиморфная форма рифаксимина и её применение
US8486956B2 (en) 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
RU2519649C2 (ru) 2008-02-26 2014-06-20 Саликс Фармасьютикалз, Лтд. Способы лечения заболеваний кишечника
SI2294012T1 (sl) 2008-05-07 2014-11-28 Salix Pharmaceuticals, Ltd. Dajanje ÄŤistila za ÄŤrevo in antibiotika za zdravljenje ÄŤrevesne bolezni
CN101585843B (zh) * 2008-05-21 2011-07-06 重庆赛诺生物药业股份有限公司 一种利福昔明的制备工艺
WO2010040020A1 (en) 2008-10-02 2010-04-08 Salix Pharmaceuticals, Ltd. Methods of treating hepatic encephalopathy
US7928115B2 (en) 2008-10-02 2011-04-19 Salix Pharmaceuticals, Ltd. Methods of treating travelers diarrhea and hepatic encephalopathy
US20110035232A1 (en) * 2008-10-02 2011-02-10 Salix Pharmaceuticals, Ltd. Methods of treating hepatic encephalopathy
KR20110107806A (ko) 2008-12-10 2011-10-04 시플라 리미티드 리팍시민 복합체
IT1397617B1 (it) * 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
BRPI1010028A2 (pt) 2009-06-02 2019-02-12 Salix Pharmaceuticals, Ltd. métodos de tratamento de encefalopatia hepática
JP2013504597A (ja) 2009-09-13 2013-02-07 サリックス ファーマスーティカルズ，リミテッド 過敏性腸症候群（ｉｂｓ）の治療方法
CA2781580A1 (en) 2009-11-23 2011-05-26 Cipla Limited Topical foam composition
US8952159B2 (en) 2009-12-28 2015-02-10 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
AU2011218129A1 (en) 2010-02-18 2012-08-23 Board Of Regents Of The University Of Texas System Methods for treating infection
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
EP2582707A4 (en) * 2010-06-16 2014-01-08 Apotex Pharmachem Inc POLYMORPHIC FORMS OF RIFAXIMINE
MY165086A (en) 2010-07-12 2018-02-28 Salix Pharmaceuticals Ltd Formulations of rifaximin and uses thereof
WO2012035544A2 (en) 2010-09-13 2012-03-22 Sequent Scientific Ltd. A novel polymorphic form of rifaximin and process for its preparation
CN103827122B (zh) 2011-02-11 2016-08-31 萨利克斯药品有限公司 利福昔明的形式及其用途
AU2012251385A1 (en) 2011-05-02 2013-11-21 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
WO2012155981A1 (en) 2011-05-19 2012-11-22 Friulchem Spa New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
CA2854380A1 (en) 2011-11-02 2013-05-10 Salix Pharmaceuticals, Ltd. Methods for treating irritable bowel syndrome (ibs) and infections
CA2876737A1 (en) 2012-06-13 2013-12-19 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
EP2971062A2 (en) 2013-03-15 2016-01-20 ALFA WASSERMANN S.p.A. Method for diagnosing vaginal infections
AU2014229467A1 (en) 2013-03-15 2015-08-06 Alfa Wassermann S.P.A. Rifaximin for use in the treating of vaginal infections.
EP2983647B1 (en) 2013-04-12 2020-09-09 Alfasigma S.p.A. Nsaid administration and related compositions, methods and systems
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
ITMI20131307A1 (it) 2013-08-02 2015-02-02 A M S A Anonima Materie Sint & Affini S P A Processo per la preparazione di refaximina k
CN103509038B (zh) * 2013-09-30 2016-01-20 浙江思贤制药有限公司 一种新晶型利福昔明ζ及其制备方法
ES2621557T3 (es) 2014-03-31 2017-07-04 Euticals S.P.A. Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
WO2015171493A1 (en) 2014-05-04 2015-11-12 Salix Pharmaceuticals, Inc. Ibs microbiota and uses thereof
JP6576953B2 (ja) 2014-05-12 2019-09-18 アルファシグマ ソシエタ ペル アチオニ リファキシミンの新規溶媒和物結晶形、生成物、組成物及びそれらの使用
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
US9988398B2 (en) 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
PT3518924T (pt) 2016-09-30 2022-10-27 Salix Pharmaceuticals Inc Formas de dispersão sólidas de rifaximina
DK3645539T3 (da) * 2017-06-26 2021-05-10 Biofer Spa Pyrido-imidazo-rifamycin-derivater som antibakterielt middel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1154655B (it) 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Also Published As

Publication number Publication date
NO851921L (no) 1985-11-18
ES8603489A1 (es) 1986-01-01
DK214685D0 (da) 1985-05-14
PT80446B (pt) 1987-11-11
NO164242C (no) 1990-09-12
DK162647C (da) 1992-04-13
DE3573120D1 (en) 1989-10-26
DK214685A (da) 1985-11-16
AU568934B2 (en) 1988-01-14
ES543115A0 (es) 1986-01-01
PT80446A (en) 1985-06-01
EP0161534A3 (en) 1987-03-04
CA1215708A (en) 1986-12-23
JPH0469634B2 (it) 1992-11-06
FI81101B (fi) 1990-05-31
NO164242B (no) 1990-06-05
IE851191L (en) 1985-11-15
ZA852971B (en) 1985-12-24
EP0161534A2 (en) 1985-11-21
AR241913A1 (es) 1993-01-29
JPS60252483A (ja) 1985-12-13
PH22007A (en) 1988-05-02
FI851907L (fi) 1985-11-16
IT1199374B (it) 1988-12-30
ATE46512T1 (de) 1989-10-15
FI851907A0 (fi) 1985-05-14
EP0161534B1 (en) 1989-09-20
GR851144B (it) 1985-11-25
DK162647B (da) 1991-11-25
IE58392B1 (en) 1993-09-08
AU4251585A (en) 1985-11-21
FI81101C (fi) 1990-09-10
US4557866A (en) 1985-12-10

Similar Documents

Publication Publication Date Title
IT8403463A0 (it) Processo per la preparazionedi pirido-imidazo-rifamicine
IT8519847A0 (it) Processo per la preparazione di fluorossi-alo-composti.
IT1191632B (it) Processo per la preparazione di (2,2)-paraciolofano
IT1136945B (it) Processo per la preparazione di l-carnitina
IT8423280A1 (it) Processo per la sintesi di 2-metossi-6-bromo-naftalene
PT81433B (pt) Processo de preparacao de comestico anti-rugas
IT1177104B (it) Processo per la preparazione di (2,2)-paraciclofano
IT1199413B (it) Processo per la preparazione di pirido-imidazo-rifamicine
IT1186782B (it) Processo per la preparazione di fenilpropanoni
IT1186708B (it) Processo per la preparazione di 2-perfluoropropossi-perfluoropropio nilfluoruro
IT8421520A0 (it) Processo per la preparazione dicomposti carbonilici.
BR8705543A (pt) Processo para preparacao de minooxazolidinas
BR8506175A (pt) Processo de preparacao de galoborossilicato
BR8601349A (pt) Processo de preparar w-lactamas
BR8502718A (pt) Processo para preparacao de 3-cloro-2-fluor-5-(trifluorometil)piridina
PT81209B (pt) Processo para preparacao de novos compostos diarilicos
BR8504396A (pt) Processo direto para a preparacao de siloxanos
IT1182751B (it) Procedimento per la produzione di orto- e para-nitrobenzaldeide
IT1175989B (it) Procedimento per la preparazione di polifenileteri
IT1173204B (it) Processo per la preparazione di novolacche
IT8403465A0 (it) Processo per la preparazione di imidazo-rifamicine
IT8420174A0 (it) Processo per la preparazione di tiocarbammati.
IT1164177B (it) Processo per la preparazione di alfa-cheto-acidi
IT1170000B (it) Processo per la preparazione di alchil-naftileteri
IT1199375B (it) Processo per la preparazione di imidazo rifamicine

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940505