IT1154655B - Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica - Google Patents
Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibattericaInfo
- Publication number
- IT1154655B IT1154655B IT03429/80A IT342980A IT1154655B IT 1154655 B IT1154655 B IT 1154655B IT 03429/80 A IT03429/80 A IT 03429/80A IT 342980 A IT342980 A IT 342980A IT 1154655 B IT1154655 B IT 1154655B
- Authority
- IT
- Italy
- Prior art keywords
- imidazo
- preparation
- antibacterial action
- rifamycin derivatives
- action substance
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT03429/80A IT1154655B (it) | 1980-05-22 | 1980-05-22 | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
NLAANVRAGE8102290,A NL187022C (nl) | 1980-05-22 | 1981-05-11 | Rifamycine derivaten met anti-bacteriele werking, en dergelijke derivaten bevattend farmaceutisch preparaat. |
US06/262,123 US4341785A (en) | 1980-05-22 | 1981-05-11 | Imidazo-rifamycin derivatives with antibacterial utility |
AU70655/81A AU537093B2 (en) | 1980-05-22 | 1981-05-18 | New imidazo-rifamycin derivatives with antibacterial utility |
AT0222781A AT373599B (de) | 1980-05-22 | 1981-05-19 | Verfahren zur herstellung neuer rifamycinderivate |
EG280/81A EG14891A (en) | 1980-05-22 | 1981-05-20 | A process for preparation of derivatives of imiadozo-new rifamicyn have process antibacterial utility |
PH25656A PH17207A (en) | 1980-05-22 | 1981-05-20 | New imidazo-rifamycin derivatives with antibacterial utility |
PT73064A PT73064B (en) | 1980-05-22 | 1981-05-20 | New imidazo-rifamycin derivatives with anti-bacterial utility |
FR8110058A FR2482967A1 (fr) | 1980-05-22 | 1981-05-20 | Nouveaux derives de l'imidazo-rifamycine, leur procede de preparation et leur application en therapeutique |
GR65010A GR75640B (it) | 1980-05-22 | 1981-05-20 | |
LU83376A LU83376A1 (fr) | 1980-05-22 | 1981-05-20 | Nouveaux derives d'imidazo-rifamycine a activite antibacterienne |
CA000378015A CA1142518A (en) | 1980-05-22 | 1981-05-21 | Imidazo-rifamycin derivatives with antibacterial utility |
NO811731A NO155622C (no) | 1980-05-22 | 1981-05-21 | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater. |
FI811565A FI69467C (fi) | 1980-05-22 | 1981-05-21 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara pyrido- och isokinolin(1',2':1,2)imidazo(5,4-c)rifamycin soch sv-derivat |
ES502906A ES8203388A1 (es) | 1980-05-22 | 1981-05-21 | Un procedimiento para la preparacion de nuevos derivados de imidazo-rifamicina |
IE1139/81A IE51204B1 (en) | 1980-05-22 | 1981-05-21 | Imidazo-rifamycin derivatives |
DK224781A DK157876C (da) | 1980-05-22 | 1981-05-21 | Analogifremgangsmaade til fremstilling af imidazo-rifamycin-derivater |
ZA00813430A ZA813430B (en) | 1980-05-22 | 1981-05-21 | New imidazo-rifamycin derivatives with antibacterial utility |
BE2/59169A BE888895A (fr) | 1980-05-22 | 1981-05-21 | Nouveaux derives d'imidazo-rifamycine a activite antibacterienne |
SE8103216A SE453089B (sv) | 1980-05-22 | 1981-05-21 | Imidazo-rifamycinderivat, forfarande for framstellning derav och farmaceutisk komposition |
DE19813120460 DE3120460A1 (de) | 1980-05-22 | 1981-05-22 | Pyridoimidazolorifamycinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
AR285424A AR226212A1 (es) | 1980-05-22 | 1981-05-22 | Procedimiento para preparar nuevos derivados de imidazo rifamicina |
GB8115790A GB2079270B (en) | 1980-05-22 | 1981-05-22 | Imidazo-rifamycin derivatives |
JP7787781A JPS5711987A (en) | 1980-05-22 | 1981-05-22 | Novel imidazo-rifamycin derivative |
CH3381/81A CH648037A5 (de) | 1980-05-22 | 1981-05-22 | Imidazo-rifamycin-derivate mit antibakterieller wirksamkeit. |
PH26842A PH18704A (en) | 1980-05-22 | 1982-02-09 | Method of treatment using inidazo-rifamycin derivatives with antibacterial utility |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT03429/80A IT1154655B (it) | 1980-05-22 | 1980-05-22 | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8003429A0 IT8003429A0 (it) | 1980-05-22 |
IT1154655B true IT1154655B (it) | 1987-01-21 |
Family
ID=11107198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT03429/80A IT1154655B (it) | 1980-05-22 | 1980-05-22 | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
Country Status (25)
Country | Link |
---|---|
US (1) | US4341785A (it) |
JP (1) | JPS5711987A (it) |
AR (1) | AR226212A1 (it) |
AT (1) | AT373599B (it) |
AU (1) | AU537093B2 (it) |
BE (1) | BE888895A (it) |
CA (1) | CA1142518A (it) |
CH (1) | CH648037A5 (it) |
DE (1) | DE3120460A1 (it) |
DK (1) | DK157876C (it) |
EG (1) | EG14891A (it) |
ES (1) | ES8203388A1 (it) |
FI (1) | FI69467C (it) |
FR (1) | FR2482967A1 (it) |
GB (1) | GB2079270B (it) |
GR (1) | GR75640B (it) |
IE (1) | IE51204B1 (it) |
IT (1) | IT1154655B (it) |
LU (1) | LU83376A1 (it) |
NL (1) | NL187022C (it) |
NO (1) | NO155622C (it) |
PH (2) | PH17207A (it) |
PT (1) | PT73064B (it) |
SE (1) | SE453089B (it) |
ZA (1) | ZA813430B (it) |
Cited By (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006094737A2 (en) | 2005-03-07 | 2006-09-14 | Alfa Wassermann S.P.A. | Gastroresistant pharmaceutical formulations containing rifaximin |
WO2007103448A2 (en) | 2006-03-09 | 2007-09-13 | Salix Pharmaceuticals, Inc. | Rifaximin anti-rectal dysfunction preparation |
WO2008016708A2 (en) | 2006-08-02 | 2008-02-07 | Salix Pharmaceuticals, Inc. | Methods for treatment of radiation enteritis |
EP2011486A1 (en) | 2007-07-06 | 2009-01-07 | Lupin Ltd. | Pharmaceutical compositions of rifaximin |
WO2009108730A2 (en) | 2008-02-25 | 2009-09-03 | Salix Pharmaceuticals, Ltd. | Forms of rifaximin and uses thereof |
WO2009108814A1 (en) | 2008-02-26 | 2009-09-03 | Salix Pharmaceuticals, Ltd. | Methods for treating bowel diseases |
WO2009137672A1 (en) | 2008-05-07 | 2009-11-12 | Salix Pharmaceuticals, Ltd. | Methods of treating bowel disease by administering a bowel cleanser and an antibiotic |
WO2010040020A1 (en) | 2008-10-02 | 2010-04-08 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
EP2208730A1 (en) | 2003-11-07 | 2010-07-21 | ALFA WASSERMANN S.p.A. | Polymorphic forms of rifaximin, processes for their production and use thereof in medicinal preparations |
WO2011051971A2 (en) | 2009-10-27 | 2011-05-05 | Lupin Limited | Solid dispersion of rifaximin |
WO2011061519A2 (en) | 2009-11-23 | 2011-05-26 | Cipla Limited | Topical foam composition |
WO2011080691A1 (en) | 2009-12-28 | 2011-07-07 | Silvio Massimo Lavagna | Method for the production of amorphous rifaximin |
MD4081G2 (ro) * | 2005-03-03 | 2011-07-31 | Alfa Wassermann S.P.A. | Forme polimorfe de rifaximină, procedee de obţinere şi utilizare a acestora în calitate de preparate medicamentoase cu activitate antibiotică |
WO2011103120A1 (en) | 2010-02-19 | 2011-08-25 | Salix Pharmaceuticals, Ltd. | Forms of rifaximin and uses thereof |
WO2011107970A2 (en) | 2010-03-05 | 2011-09-09 | Alfa Wassermann S.P.A. | Rifaximin powder, process for preparing the same and controlled release compositions containing said rifaximin useful for obtaining a long-lasting effect. |
WO2011110930A2 (en) | 2010-03-10 | 2011-09-15 | Lupin Limited | Rifaximin ready-to-use suspension |
WO2012009388A1 (en) | 2010-07-12 | 2012-01-19 | Salix Pharmaceuticals, Ltd | Formulations of rifaximin and uses thereof |
WO2012109605A2 (en) | 2011-02-11 | 2012-08-16 | Salix Pharmaceuticals, Ltd. | Forms of rifaximin and uses thereof |
WO2013017928A1 (en) | 2011-07-29 | 2013-02-07 | Alfa Wassermann S.P.A. | Pharmaceutical compositions comprising rifaximin, processes for their preparation and their use in the treatment of vaginal infections |
US8383151B2 (en) | 2007-07-06 | 2013-02-26 | Lupin Limited | Pharmaceutical compositions of rifaximin |
WO2013067394A1 (en) | 2011-11-02 | 2013-05-10 | Salix Pharmaceuticals, Ltd | Methods for treating irritable bowel syndrome (ibs) and infections |
WO2014006576A1 (en) | 2012-07-06 | 2014-01-09 | Alfa Wassermann S.P.A. | Pharmaceutical compositions comprising rifaximin and amino acids, preparation method and use thereof |
WO2014140995A2 (en) | 2013-03-15 | 2014-09-18 | Alfa Wassermann S.P.A. | Method for diagnosing vaginal infections |
WO2014140988A1 (en) | 2013-03-15 | 2014-09-18 | Alfa Wassermann S.P.A. | Rifaximin for use in the treating of vaginal infections. |
WO2014167533A1 (en) | 2013-04-12 | 2014-10-16 | Alfa Wassermann S.P.A. | Nsaid administration and related compositions, methods and systems. |
WO2015171493A1 (en) | 2014-05-04 | 2015-11-12 | Salix Pharmaceuticals, Inc. | Ibs microbiota and uses thereof |
WO2015173697A1 (en) | 2014-05-12 | 2015-11-19 | Alfa Wassermann S.P.A. | New solvated crystal form of rifaximin, production, compositions and uses thereof |
EP2982764A1 (en) | 2014-08-05 | 2016-02-10 | ALFA WASSERMANN S.p.A. | Identification of vaginal bacteria |
US9988398B2 (en) | 2016-06-07 | 2018-06-05 | Cadila Healthcare Limited | Crystalline form of rifaximin and process for its preparation |
EP3650022A1 (en) | 2010-02-18 | 2020-05-13 | Salix Pharmaceuticals, Ltd. | Methods for treating rifampin resistant clostridium difficilis infections |
EP3964066A1 (en) | 2009-06-02 | 2022-03-09 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1199374B (it) | 1984-05-15 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
IT1264494B1 (it) * | 1993-03-23 | 1996-09-24 | Alfa Wassermann Spa | Uso di rifaximin e di formulazioni che la contengono nel trattamento delle dispepsie gastriche originate da helicobacter |
US6861053B1 (en) * | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US5981522A (en) * | 1995-09-01 | 1999-11-09 | Kaneka Corporation | Treatment of disease caused by infection of Helicobacter |
DE69829905T2 (de) * | 1997-02-28 | 2006-03-09 | Kaneka Corp. | Heilmittel für durch Helicobacter verursachte Krankheit |
CA2465846A1 (en) * | 2001-11-21 | 2003-06-05 | Activbiotics, Inc. | Targeted therapeutics and uses thereof |
WO2003051299A2 (en) * | 2001-12-13 | 2003-06-26 | Activbiotics, Inc. | Sulfhydryl rifamycins and uses thereof |
ES2385477T3 (es) * | 2002-11-05 | 2012-07-25 | Fadim S.R.L. | Liberación continua y controlada de rifaximina |
US7820652B2 (en) * | 2003-09-24 | 2010-10-26 | Activbiotics Pharma, Llc | Regimen for the administration of rifamycin-class antibiotics |
US7906542B2 (en) * | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
US7923553B2 (en) * | 2003-11-07 | 2011-04-12 | Alfa Wassermann, S.P.A. | Processes for the production of polymorphic forms of rifaximin |
US20080262024A1 (en) * | 2003-11-07 | 2008-10-23 | Giuseppe Claudio Viscomi | Rifaximin compositions and method of use |
US7902206B2 (en) * | 2003-11-07 | 2011-03-08 | Alfa Wassermann, S.P.A. | Polymorphic forms α, β and γ of rifaximin |
US7265107B2 (en) * | 2004-03-10 | 2007-09-04 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes |
US7256187B2 (en) * | 2004-03-10 | 2007-08-14 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime derivatives effective against drug-resistant microbes |
US7202246B2 (en) * | 2004-06-09 | 2007-04-10 | Cumbre Pharmaceuticals Inc. | Spiro-rifamycin derivatives targeting RNA polymerase |
US20060210492A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Use of rifaximin for treatment and prevention of periodontal conditions |
US20060210483A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections |
US8003118B2 (en) * | 2005-03-02 | 2011-08-23 | Kodsi Robert E | Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis |
JP5368092B2 (ja) | 2005-08-11 | 2013-12-18 | ターガンタ セラピュティクス,インコーポレイティド | ホスホン化リファマイシン類および骨と関節感染の予防と治療のためのその投与法 |
ITMI20061692A1 (it) | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
US8633234B2 (en) * | 2006-09-22 | 2014-01-21 | Cipla Limited | Rifaximin |
US20080161337A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Chronic Prostatitis |
US20080159987A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Restless Legs Syndrome |
ITMI20071241A1 (it) * | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
US11779571B2 (en) | 2008-02-26 | 2023-10-10 | Salix Pharmaceuticals, Inc. | Methods for treating irritable bowel syndrome (IBS) |
EP2324041A4 (en) | 2008-08-13 | 2012-06-13 | Targanta Therapeutics Corp | PHOSPHONIZED RIFAMYCINS AND ITS APPLICATION FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS |
KR20110071096A (ko) | 2008-09-26 | 2011-06-28 | 아스카 세이야쿠 가부시키가이샤 | 기능성 소화관 장해의 예방 및/또는 치료제 |
WO2010067072A1 (en) | 2008-12-10 | 2010-06-17 | Cipla Limited | Rifaximin complexes |
IT1397617B1 (it) * | 2009-04-20 | 2013-01-18 | Alfa Wassermann Spa | Nuovi derivati della rifamicina |
JP2013504597A (ja) | 2009-09-13 | 2013-02-07 | サリックス ファーマスーティカルズ,リミテッド | 過敏性腸症候群(ibs)の治療方法 |
US8759513B2 (en) | 2010-09-13 | 2014-06-24 | Sequent Scientific Limited | Polymorphic form of rifaximin and process for its preparation |
CA2834829A1 (en) | 2011-05-02 | 2012-11-08 | Ranbaxy Laboratories Limited | Rifaximin dimethylformamide solvate |
ITMI20110890A1 (it) * | 2011-05-19 | 2012-11-20 | A M S A Anonima Materie Sint & Affini S P A | Polimorfo di rifaximina e processo per la sua preparazione |
RU2496475C2 (ru) | 2011-10-26 | 2013-10-27 | Александр Васильевич Иващенко | Фармацевтическая композиция и набор для лечения бактериальных инфекций |
JP2015509105A (ja) * | 2012-01-25 | 2015-03-26 | サリックス ファーマスーティカルズ,リミテッド | リファキシミン誘導体及びその使用 |
US9849090B2 (en) | 2012-12-12 | 2017-12-26 | Sun Pharmaceutical Industries Limited | Pharmaceutical compositions of rifaximin |
US9018225B1 (en) | 2013-07-26 | 2015-04-28 | Novel Laboratories | Rifaximin crystalline forms and methods of preparation thereof |
ES2621557T3 (es) | 2014-03-31 | 2017-07-04 | Euticals S.P.A. | Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas |
EP4137132A1 (en) | 2016-09-30 | 2023-02-22 | Salix Pharmaceuticals, Inc. | Solid dispersion forms of rifaximin |
PL3645539T3 (pl) * | 2017-06-26 | 2021-10-25 | Biofer S.P.A. | Pochodne pirydoimidazoryfamycyny jako środek przeciwbakteryjny |
IT201700091912A1 (it) * | 2017-08-08 | 2019-02-08 | Biofer Spa | Nuove pirido-imidazo rifamicine |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE273377C (it) * | ||||
AT273377B (de) * | 1967-03-01 | 1969-08-11 | Lepetit Spa | Verfahren zur Herstellung von neuen Rifamycinen |
AT344898B (de) * | 1975-06-13 | 1978-08-10 | Archifar Ind Chim Trentino | Verfahren zur herstellung neuer rifamycin-verbindungen |
DK345977A (da) * | 1976-09-30 | 1978-03-31 | Archifar Ind Chim Trentino | G rifamycinforbindelser og fremgangsmaade til deres fremstillin |
CH629212A5 (it) * | 1976-10-18 | 1982-04-15 | Erba Farmitalia | Procedimento per la preparazione di composti di rifamicina. |
CH633014A5 (en) * | 1978-06-09 | 1982-11-15 | Erba Farmitalia | Rifamycin compounds |
-
1980
- 1980-05-22 IT IT03429/80A patent/IT1154655B/it active Protection Beyond IP Right Term
-
1981
- 1981-05-11 NL NLAANVRAGE8102290,A patent/NL187022C/xx not_active IP Right Cessation
- 1981-05-11 US US06/262,123 patent/US4341785A/en not_active Expired - Lifetime
- 1981-05-18 AU AU70655/81A patent/AU537093B2/en not_active Expired
- 1981-05-19 AT AT0222781A patent/AT373599B/de not_active IP Right Cessation
- 1981-05-20 GR GR65010A patent/GR75640B/el unknown
- 1981-05-20 FR FR8110058A patent/FR2482967A1/fr active Granted
- 1981-05-20 PH PH25656A patent/PH17207A/en unknown
- 1981-05-20 PT PT73064A patent/PT73064B/pt unknown
- 1981-05-20 LU LU83376A patent/LU83376A1/fr unknown
- 1981-05-20 EG EG280/81A patent/EG14891A/xx active
- 1981-05-21 ZA ZA00813430A patent/ZA813430B/xx unknown
- 1981-05-21 CA CA000378015A patent/CA1142518A/en not_active Expired
- 1981-05-21 NO NO811731A patent/NO155622C/no unknown
- 1981-05-21 DK DK224781A patent/DK157876C/da active
- 1981-05-21 IE IE1139/81A patent/IE51204B1/en not_active IP Right Cessation
- 1981-05-21 BE BE2/59169A patent/BE888895A/fr not_active IP Right Cessation
- 1981-05-21 ES ES502906A patent/ES8203388A1/es not_active Expired
- 1981-05-21 SE SE8103216A patent/SE453089B/sv not_active IP Right Cessation
- 1981-05-21 FI FI811565A patent/FI69467C/fi not_active IP Right Cessation
- 1981-05-22 JP JP7787781A patent/JPS5711987A/ja active Granted
- 1981-05-22 CH CH3381/81A patent/CH648037A5/de not_active IP Right Cessation
- 1981-05-22 GB GB8115790A patent/GB2079270B/en not_active Expired
- 1981-05-22 DE DE19813120460 patent/DE3120460A1/de active Granted
- 1981-05-22 AR AR285424A patent/AR226212A1/es active
-
1982
- 1982-02-09 PH PH26842A patent/PH18704A/en unknown
Cited By (52)
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EP2210893A1 (en) | 2003-11-07 | 2010-07-28 | ALFA WASSERMANN S.p.A. | Polymorphous forms of rifaximin as antibiotics |
EP2208730A1 (en) | 2003-11-07 | 2010-07-21 | ALFA WASSERMANN S.p.A. | Polymorphic forms of rifaximin, processes for their production and use thereof in medicinal preparations |
US9271968B2 (en) | 2005-03-03 | 2016-03-01 | Alfa Wassermann S.P.A. | Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations |
US8518949B2 (en) | 2005-03-03 | 2013-08-27 | Alfa Wassermann S.P.A. | Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations |
MD4081G2 (ro) * | 2005-03-03 | 2011-07-31 | Alfa Wassermann S.P.A. | Forme polimorfe de rifaximină, procedee de obţinere şi utilizare a acestora în calitate de preparate medicamentoase cu activitate antibiotică |
WO2006094737A2 (en) | 2005-03-07 | 2006-09-14 | Alfa Wassermann S.P.A. | Gastroresistant pharmaceutical formulations containing rifaximin |
MD4180C1 (ro) * | 2005-03-07 | 2013-03-31 | Alfa Wassermann S.P.A. | Procedeu de fabricare a compoziţiilor farmaceutice cu conţinut de rifaximină sub formă de microgranule gastrorezistente, compoziţii şi utilizarea lor în tratamentul afecţiunilor inflamatoare ale intestinelor |
WO2007103448A2 (en) | 2006-03-09 | 2007-09-13 | Salix Pharmaceuticals, Inc. | Rifaximin anti-rectal dysfunction preparation |
WO2008016708A2 (en) | 2006-08-02 | 2008-02-07 | Salix Pharmaceuticals, Inc. | Methods for treatment of radiation enteritis |
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